SK281413B6 - Purifikovaná a izolovaná polynukleotidová sekvencia kódujúca humánny protokaderín pc3, vektor, hostiteľská bunka, humánny protokaderín pc3, spôsob jeho produkcie a spôsob modulácie jeho väzbovej aktivity, protilátka a bunková línia - Google Patents

Purifikovaná a izolovaná polynukleotidová sekvencia kódujúca humánny protokaderín pc3, vektor, hostiteľská bunka, humánny protokaderín pc3, spôsob jeho produkcie a spôsob modulácie jeho väzbovej aktivity, protilátka a bunková línia Download PDF

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Publication number
SK281413B6
SK281413B6 SK252-96A SK25296A SK281413B6 SK 281413 B6 SK281413 B6 SK 281413B6 SK 25296 A SK25296 A SK 25296A SK 281413 B6 SK281413 B6 SK 281413B6
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SK
Slovakia
Prior art keywords
seq
leu
ala
thr
protocadherin
Prior art date
Application number
SK252-96A
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English (en)
Slovak (sk)
Other versions
SK25296A3 (en
Inventor
Shinatro Suzuki
Original Assignee
Doheny Eye Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Doheny Eye Institute filed Critical Doheny Eye Institute
Publication of SK25296A3 publication Critical patent/SK25296A3/sk
Publication of SK281413B6 publication Critical patent/SK281413B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SK252-96A 1994-06-27 1995-06-26 Purifikovaná a izolovaná polynukleotidová sekvencia kódujúca humánny protokaderín pc3, vektor, hostiteľská bunka, humánny protokaderín pc3, spôsob jeho produkcie a spôsob modulácie jeho väzbovej aktivity, protilátka a bunková línia SK281413B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/268,161 US5798224A (en) 1992-12-29 1994-06-27 Nucleic acids encoding protocadherin
PCT/US1995/008071 WO1996000289A1 (fr) 1994-06-27 1995-06-26 Proteines protocadherines et leurs utilisations

Publications (2)

Publication Number Publication Date
SK25296A3 SK25296A3 (en) 1997-02-05
SK281413B6 true SK281413B6 (sk) 2001-03-12

Family

ID=23021746

Family Applications (1)

Application Number Title Priority Date Filing Date
SK252-96A SK281413B6 (sk) 1994-06-27 1995-06-26 Purifikovaná a izolovaná polynukleotidová sekvencia kódujúca humánny protokaderín pc3, vektor, hostiteľská bunka, humánny protokaderín pc3, spôsob jeho produkcie a spôsob modulácie jeho väzbovej aktivity, protilátka a bunková línia

Country Status (18)

Country Link
US (5) US5798224A (fr)
EP (1) EP0719330B1 (fr)
JP (1) JP3560344B2 (fr)
CN (1) CN1105187C (fr)
AT (1) ATE309347T1 (fr)
AU (1) AU699135B2 (fr)
BR (1) BR9506058A (fr)
CA (1) CA2170156A1 (fr)
CZ (1) CZ288789B6 (fr)
DE (1) DE69534588D1 (fr)
FI (1) FI960888A (fr)
HU (1) HU221637B1 (fr)
MX (1) MX9600666A (fr)
NO (1) NO319686B1 (fr)
PL (1) PL182324B1 (fr)
RU (1) RU2197525C2 (fr)
SK (1) SK281413B6 (fr)
WO (1) WO1996000289A1 (fr)

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AU2582897A (en) * 1996-03-15 1997-10-01 Millennium Pharmaceuticals, Inc. Compositions and methods for the diagnosis, prevention, and treatment of neoplastic cell growth and proliferation
EP0970108A2 (fr) * 1997-01-09 2000-01-12 Genetics Institute, Inc. Proteines secretees et polynucleotides les codant
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO1999029860A1 (fr) * 1997-12-08 1999-06-17 Ontogeny, Inc. Polypeptides de type cadherine, procedes et compositions associes
JP2001526035A (ja) * 1997-12-10 2001-12-18 シーエスエル、リミテッド Ｐｏｒｐｈｏｒｙｍｏｎａｓｇｉｎｇｉｖａｌｉｓポリペプチドおよびヌクレオチド
ATE286508T1 (de) * 1998-03-26 2005-01-15 Genentech Inc Nukleinsäure die in menschliche tumoren vervielfältigt sind, und damit zusammenhängende materiale und verfahren
US6472367B1 (en) 1998-05-05 2002-10-29 Adherex Technologies, Inc. Compounds and methods for modulating OB-cadherin mediated cell adhesion
US6680175B2 (en) * 1998-05-05 2004-01-20 Adherex Technologies, Inc. Methods for diagnosing and evaluating cancer
US7481999B2 (en) * 1998-05-05 2009-01-27 Adherex Technologies, Inc. Compounds and methods for modulating OB-cadherin-mediated function
US6638911B1 (en) 1998-05-05 2003-10-28 Adherex Technologies Inc. Compounds and methods for modulating desmosomal cadherin-mediated functions
US20050203025A1 (en) * 1998-05-05 2005-09-15 Adherex Technologies, Inc. Compounds and methods for modulating nonclassical cadherin-mediated functions
US6277824B1 (en) * 1998-07-10 2001-08-21 Adherex Technologies Compounds and methods for modulating adhesion molecule function
US20030096951A1 (en) * 1998-08-14 2003-05-22 Kenneth Jacobs Secreted proteins and polynucleotides encoding them
US7041807B1 (en) 1999-06-23 2006-05-09 Caprion Pharmaceuticals, Inc. Antibodies to a YYX epitope of a mammalian prion protein
US6787136B1 (en) * 1999-09-03 2004-09-07 The Brigham And Women's Hospital, Inc. Methods and compositions for treatment of inflammatory disease using cadherin-11 modulating agents
US7193050B2 (en) 2000-02-18 2007-03-20 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CN1313328A (zh) * 2000-03-15 2001-09-19 上海博德基因开发有限公司 一种新的多肽——人原钙粘素14和编码这种多肽的多核苷酸
AU2001275306A1 (en) * 2000-06-06 2001-12-17 Genaissance Pharmaceuticals, Inc. Haplotypes of the pcdh2 gene
US6790636B1 (en) * 2000-06-14 2004-09-14 The United States Of America As Represented By The Department Of Health And Human Services Rapid fluorescent labeling of tissue for microdissection using fluorescent specific binding agents
IL153943A0 (en) * 2000-07-19 2003-07-31 Upjohn Co SUBSTRATES AND ASSAYS FOR beta-SECRETASE ACTIVITY
US7122311B2 (en) * 2001-07-16 2006-10-17 Novartis Ag Methods for determining the risk of developing asthma characterized by bronchial hyperresponsiveness
US20040072236A1 (en) * 2002-09-27 2004-04-15 Neil Cashman PrPSc -interacting molecules and uses thereof
AU2003298475A1 (en) * 2002-11-14 2004-06-18 Adherex Technologies, Inc. Compounds and methods for modulating desmosomal and atypical cadherin-mediated cell adhesion
CN101492673B (zh) * 2008-01-25 2012-01-11 中国科学院上海生命科学研究院 非洲爪蟾xpapc基因启动子及其组织特异性增强子
CN102274501A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 一种治疗或预防癌症的药物
CN102274507A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 一种用于治疗或预防癌症的药物
CN102274506A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 治疗或预防癌症的药物
CN102274509A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 治疗或预防癌症的药物
CN102274490A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 一种用于治疗或预防癌症的药物
CN102274503A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 治疗或预防癌症的药物
CN102274499A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 用于治疗或预防癌症的药物
CN102274489A (zh) * 2008-09-07 2011-12-14 苏州爱生基因有限公司 治疗或预防癌症的药物
CA2759538C (fr) * 2009-04-20 2018-07-24 Oxford Biotherapeutics Ltd Anticorps specifiques a la cadherine-17
WO2011115268A1 (fr) * 2010-03-18 2011-09-22 大日本住友製薬株式会社 Inhibiteur d'angiogenèse de tumeur
US8877188B2 (en) 2010-05-04 2014-11-04 The Brigham And Women's Hospital, Inc. Detection and treatment of non-dermal fibrosis
US9534058B2 (en) 2012-02-08 2017-01-03 Abbvie Stemcentrx Llc Anti-CD324 monoclonal antibodies and uses thereof
CN103194476A (zh) * 2013-04-07 2013-07-10 新乡医学院 鸡pcdh1基因部分片段的克隆、表达及多克隆抗体的制备
WO2016024195A1 (fr) * 2014-08-12 2016-02-18 Novartis Ag Conjugués médicament-anticorps anti-cdh6
US11097005B2 (en) 2014-12-15 2021-08-24 The Brigham And Women's Hospital, Inc. Use of cadherin-11 antagonists to treat metabolic disorders and/or increase insulin sensitivity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2067183A1 (fr) * 1989-09-27 1991-03-28 Lee L. Rubin Composition pour l'inhibition de l'adhesion cellulaire et methode d'utilisation
JPH06505962A (ja) * 1990-10-30 1994-07-07 ラ　ホヤ　キャンサー　リサーチ　ファウンデーション Ｔ−カドヘリン接着分子

Also Published As

Publication number Publication date
CN1105187C (zh) 2003-04-09
FI960888A0 (fi) 1996-02-26
RU2197525C2 (ru) 2003-01-27
BR9506058A (pt) 1997-08-05
US6262237B1 (en) 2001-07-17
HUT75825A (en) 1997-05-28
ATE309347T1 (de) 2005-11-15
AU699135B2 (en) 1998-11-26
NO319686B1 (no) 2005-09-05
HU9600449D0 (en) 1996-04-29
PL313256A1 (en) 1996-06-24
DE69534588D1 (de) 2005-12-15
AU2872495A (en) 1996-01-19
WO1996000289A1 (fr) 1996-01-04
HU221637B1 (hu) 2002-12-28
US20030139581A1 (en) 2003-07-24
MX9600666A (es) 1997-06-28
PL182324B1 (pl) 2001-12-31
CZ288789B6 (cs) 2001-09-12
JPH09505740A (ja) 1997-06-10
NO960767D0 (no) 1996-02-26
NO960767L (no) 1996-04-26
EP0719330B1 (fr) 2005-11-09
EP0719330A1 (fr) 1996-07-03
CZ48296A3 (en) 1996-11-13
US5891706A (en) 1999-04-06
FI960888A (fi) 1996-02-26
JP3560344B2 (ja) 2004-09-02
CA2170156A1 (fr) 1996-01-04
US5708143A (en) 1998-01-13
CN1134172A (zh) 1996-10-23
SK25296A3 (en) 1997-02-05
US5798224A (en) 1998-08-25

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