SK280873B6 - Taxán s protinádorovou aktivitou, spôsob jeho prípravy a farmaceutický prípravok - Google Patents

Taxán s protinádorovou aktivitou, spôsob jeho prípravy a farmaceutický prípravok Download PDF

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Publication number
SK280873B6
SK280873B6 SK60-95A SK6095A SK280873B6 SK 280873 B6 SK280873 B6 SK 280873B6 SK 6095 A SK6095 A SK 6095A SK 280873 B6 SK280873 B6 SK 280873B6
Authority
SK
Slovakia
Prior art keywords
formula
compound
taxane
preparation
antitumor activity
Prior art date
Application number
SK60-95A
Other languages
English (en)
Slovak (sk)
Other versions
SK6095A3 (en
Inventor
Bruno Gabetta
Ezio Bombardelli
Original Assignee
Indena S. P. A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena S. P. A. filed Critical Indena S. P. A.
Publication of SK6095A3 publication Critical patent/SK6095A3/sk
Publication of SK280873B6 publication Critical patent/SK280873B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SK60-95A 1993-05-20 1994-05-03 Taxán s protinádorovou aktivitou, spôsob jeho prípravy a farmaceutický prípravok SK280873B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM930334A IT1261667B (it) 1993-05-20 1993-05-20 Tassano ad attivita' antitumorale.
PCT/EP1994/001405 WO1994027984A1 (en) 1993-05-20 1994-05-03 Taxane having antitumor activity

Publications (2)

Publication Number Publication Date
SK6095A3 SK6095A3 (en) 1995-07-11
SK280873B6 true SK280873B6 (sk) 2000-08-14

Family

ID=11401772

Family Applications (1)

Application Number Title Priority Date Filing Date
SK60-95A SK280873B6 (sk) 1993-05-20 1994-05-03 Taxán s protinádorovou aktivitou, spôsob jeho prípravy a farmaceutický prípravok

Country Status (22)

Country Link
US (1) US5407674A (de)
EP (1) EP0625517B1 (de)
JP (1) JPH07509259A (de)
KR (1) KR100315495B1 (de)
CN (1) CN1054381C (de)
AT (1) ATE174595T1 (de)
AU (1) AU6795194A (de)
CA (1) CA2140519A1 (de)
CZ (1) CZ286959B6 (de)
DE (2) DE69322619T2 (de)
DK (1) DK0625517T3 (de)
ES (1) ES2068166T3 (de)
FI (1) FI950207A0 (de)
GR (1) GR950300009T1 (de)
HK (1) HK1012628A1 (de)
HU (1) HU221503B (de)
IT (1) IT1261667B (de)
NO (1) NO310510B1 (de)
PL (1) PL178363B1 (de)
RU (1) RU2129551C1 (de)
SK (1) SK280873B6 (de)
WO (1) WO1994027984A1 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4139993A1 (de) * 1991-12-04 1993-06-09 Merck Patent Gmbh, 6100 Darmstadt, De Pigmentzubereitung
IT1275936B1 (it) * 1995-03-17 1997-10-24 Indena Spa Derivati della 10-deacetilbaccatina iii e della 10-deacetil-14b- idrossibaccatina iii loro metodo di preparazione e formulazioni
US5756536A (en) * 1995-11-03 1998-05-26 Purdue Research Foundation Microbial transformation of taxol and cephalomannine
US5965752A (en) * 1996-08-23 1999-10-12 Institut National De La Recherche Scientifique Preparative scale isolation and purification of taxanes
CA2188190A1 (en) 1996-10-18 1998-04-18 Sarala Balachandran The semi-synthesis of a protected bacatin iii compound
WO1998017656A1 (en) * 1996-10-24 1998-04-30 Institute Armand-Frappier A family of canadensol taxanes, the semi-synthetic preparation and therapeutic use thereof
EP2289549A3 (de) 1999-10-01 2011-06-15 Immunogen, Inc. Immunokonjugate für Krebsbehandlung
JP2003522171A (ja) 2000-02-02 2003-07-22 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド 抗腫瘍剤としてのc10カーボネート置換タキサン
US6649632B2 (en) * 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
US7064980B2 (en) * 2003-09-17 2006-06-20 Sandisk Corporation Non-volatile memory and method with bit line coupled compensation
PE20050693A1 (es) * 2004-02-13 2005-09-27 Univ Florida State Res Found Taxanos sustituidos con esteres de ciclopentilo en c10
US7169307B2 (en) * 2004-09-02 2007-01-30 Jian Liu Process for the extraction of paclitaxel and 9-dihydro-13-acetylbaccatin III from Taxus
TW200640447A (en) * 2005-02-14 2006-12-01 Univ Florida State Res Found C10 cyclopropyl ester substituted taxane compositions
EP1883627B1 (de) 2005-05-18 2018-04-18 Pharmascience Inc. An die bir-domäne bindende verbindungen
US9127208B2 (en) * 2006-04-03 2015-09-08 Pharmatherm Chemicals, Inc. Thermal extraction method and product
AU2007250443B2 (en) 2006-05-16 2013-06-13 Pharmascience Inc. IAP BIR domain binding compounds
US7905990B2 (en) * 2007-11-20 2011-03-15 Ensyn Renewables, Inc. Rapid thermal conversion of biomass
EP2080764B1 (de) 2008-01-18 2012-08-22 INDENA S.p.A. Feste Formen von Ortataxel
WO2009145981A1 (en) * 2008-03-31 2009-12-03 Florida State University Research Foundation, Inc. C(10) ethyl ester and c(10) cyclopropyl ester substituted taxanes
ES2625637T3 (es) 2010-02-12 2017-07-20 Pharmascience Inc. Compuestos de unión al dominio BIR IAP
US20110284359A1 (en) 2010-05-20 2011-11-24 Uop Llc Processes for controlling afterburn in a reheater and for controlling loss of entrained solid particles in combustion product flue gas
US8499702B2 (en) 2010-07-15 2013-08-06 Ensyn Renewables, Inc. Char-handling processes in a pyrolysis system
US9441887B2 (en) 2011-02-22 2016-09-13 Ensyn Renewables, Inc. Heat removal and recovery in biomass pyrolysis
US9347005B2 (en) 2011-09-13 2016-05-24 Ensyn Renewables, Inc. Methods and apparatuses for rapid thermal processing of carbonaceous material
US10400175B2 (en) 2011-09-22 2019-09-03 Ensyn Renewables, Inc. Apparatuses and methods for controlling heat for rapid thermal processing of carbonaceous material
US9044727B2 (en) 2011-09-22 2015-06-02 Ensyn Renewables, Inc. Apparatuses and methods for controlling heat for rapid thermal processing of carbonaceous material
US10041667B2 (en) 2011-09-22 2018-08-07 Ensyn Renewables, Inc. Apparatuses for controlling heat for rapid thermal processing of carbonaceous material and methods for the same
US9109177B2 (en) 2011-12-12 2015-08-18 Ensyn Renewables, Inc. Systems and methods for renewable fuel
US9670413B2 (en) 2012-06-28 2017-06-06 Ensyn Renewables, Inc. Methods and apparatuses for thermally converting biomass
TWI645026B (zh) 2013-06-26 2018-12-21 安信再生公司 可再生燃料之系統及方法
CA2995845A1 (en) 2015-08-21 2017-03-02 Ensyn Renewables, Inc. Liquid biomass heating system
CA3048681A1 (en) 2016-12-29 2018-07-05 Ensyn Renewables, Inc. Demetallization of liquid biomass

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206221A (en) * 1979-01-03 1980-06-03 The United States Of America As Represented By The Secretary Of Agriculture Cephalomannine and its use in treating leukemic tumors
US4942184A (en) * 1988-03-07 1990-07-17 The United States Of America As Represented By The Department Of Health And Human Services Water soluble, antineoplastic derivatives of taxol
US5157049A (en) * 1988-03-07 1992-10-20 The United States Of America As Represented By The Department Of Health & Human Services Method of treating cancers sensitive to treatment with water soluble derivatives of taxol
FR2662441B1 (fr) * 1990-05-22 1992-10-23 Rhone Poulenc Sante Procede de preparation enantioselective de derives de la phenylisoserine.
US5250683A (en) * 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides
US5243045A (en) * 1991-09-23 1993-09-07 Florida State University Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
US5227400A (en) * 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
IT1254515B (it) * 1992-03-06 1995-09-25 Indena Spa Tassani di interesse oncologico, loro metodo di preparazione ed uso
US5200534A (en) * 1992-03-13 1993-04-06 University Of Florida Process for the preparation of taxol and 10-deacetyltaxol

Also Published As

Publication number Publication date
SK6095A3 (en) 1995-07-11
CN1110055A (zh) 1995-10-11
CZ286959B6 (en) 2000-08-16
PL178363B1 (pl) 2000-04-28
DK0625517T3 (da) 1999-08-23
ES2068166T3 (es) 1999-03-01
GR950300009T1 (en) 1995-03-31
KR100315495B1 (ko) 2002-06-20
FI950207A (fi) 1995-01-18
US5407674A (en) 1995-04-18
ES2068166T1 (es) 1995-04-16
HU9500152D0 (en) 1995-03-28
ITRM930334A1 (it) 1994-11-20
EP0625517A1 (de) 1994-11-23
NO310510B1 (no) 2001-07-16
ITRM930334A0 (it) 1993-05-20
ATE174595T1 (de) 1999-01-15
AU6795194A (en) 1994-12-20
RU2129551C1 (ru) 1999-04-27
CZ12295A3 (en) 1995-09-13
JPH07509259A (ja) 1995-10-12
FI950207A0 (fi) 1995-01-18
RU95105981A (ru) 1996-10-27
CA2140519A1 (en) 1994-12-08
CN1054381C (zh) 2000-07-12
HU221503B (en) 2002-10-28
DE625517T1 (de) 1995-07-13
NO950184D0 (no) 1995-01-18
NO950184L (no) 1995-01-18
DE69322619T2 (de) 1999-06-24
WO1994027984A1 (en) 1994-12-08
PL307089A1 (en) 1995-05-02
DE69322619D1 (de) 1999-01-28
IT1261667B (it) 1996-05-29
EP0625517B1 (de) 1998-12-16
HK1012628A1 (en) 1999-08-06
HUT72607A (en) 1996-05-28

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