SK279610B6 - Spôsob izolácie kryštalickej alfa, alfa-trehalózy - Google Patents
Spôsob izolácie kryštalickej alfa, alfa-trehalózy Download PDFInfo
- Publication number
- SK279610B6 SK279610B6 SK697-95A SK69795A SK279610B6 SK 279610 B6 SK279610 B6 SK 279610B6 SK 69795 A SK69795 A SK 69795A SK 279610 B6 SK279610 B6 SK 279610B6
- Authority
- SK
- Slovakia
- Prior art keywords
- trehalose
- alpha
- ethanol
- concentration
- membrane
- Prior art date
Links
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 title claims abstract description 34
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 title claims abstract description 34
- 238000000034 method Methods 0.000 title claims abstract description 26
- 238000002955 isolation Methods 0.000 title claims abstract description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 44
- 239000012528 membrane Substances 0.000 claims abstract description 20
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 14
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims abstract description 14
- 238000001471 micro-filtration Methods 0.000 claims abstract description 12
- 239000011148 porous material Substances 0.000 claims abstract description 8
- 229920001577 copolymer Polymers 0.000 claims abstract description 6
- 150000001450 anions Chemical class 0.000 claims abstract description 4
- UEEJHVSXFDXPFK-UHFFFAOYSA-N N-dimethylaminoethanol Chemical group CN(C)CCO UEEJHVSXFDXPFK-UHFFFAOYSA-N 0.000 claims abstract description 3
- 230000002378 acidificating effect Effects 0.000 claims abstract description 3
- 238000005115 demineralization Methods 0.000 claims abstract description 3
- 239000000469 ethanolic extract Substances 0.000 claims abstract description 3
- 150000001768 cations Chemical class 0.000 claims abstract 2
- 238000000108 ultra-filtration Methods 0.000 claims description 15
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 10
- 238000000605 extraction Methods 0.000 claims description 3
- 150000002500 ions Chemical class 0.000 claims description 3
- 238000004042 decolorization Methods 0.000 claims description 2
- 238000005374 membrane filtration Methods 0.000 claims description 2
- 239000007787 solid Substances 0.000 claims description 2
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 claims description 2
- 238000002425 crystallisation Methods 0.000 abstract description 5
- 230000008025 crystallization Effects 0.000 abstract description 5
- 150000002016 disaccharides Chemical class 0.000 abstract description 4
- 238000001953 recrystallisation Methods 0.000 abstract description 2
- 230000002328 demineralizing effect Effects 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 10
- 239000000243 solution Substances 0.000 description 10
- 238000001914 filtration Methods 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 239000012065 filter cake Substances 0.000 description 5
- 238000005406 washing Methods 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 239000000706 filtrate Substances 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 239000002994 raw material Substances 0.000 description 4
- 239000006188 syrup Substances 0.000 description 4
- 235000020357 syrup Nutrition 0.000 description 4
- 239000007864 aqueous solution Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 230000003544 deproteinization Effects 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- -1 α, α-trehalose disaccharide Chemical class 0.000 description 2
- 241000611223 Selaginella lepidophylla Species 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 238000005349 anion exchange Methods 0.000 description 1
- RQPZNWPYLFFXCP-UHFFFAOYSA-L barium dihydroxide Chemical compound [OH-].[OH-].[Ba+2] RQPZNWPYLFFXCP-UHFFFAOYSA-L 0.000 description 1
- 229910001863 barium hydroxide Inorganic materials 0.000 description 1
- 229940041514 candida albicans extract Drugs 0.000 description 1
- 238000005341 cation exchange Methods 0.000 description 1
- 239000003610 charcoal Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000002242 deionisation method Methods 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000005445 natural material Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000010815 organic waste Substances 0.000 description 1
- 229920002492 poly(sulfone) Polymers 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 238000003828 vacuum filtration Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 1
- 229960001763 zinc sulfate Drugs 0.000 description 1
- 229910000368 zinc sulfate Inorganic materials 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/12—Disaccharides
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CZ932025A CZ281723B6 (cs) | 1993-09-28 | 1993-09-28 | Způsob izolace krystalické alfa, alfa-trehalosy |
| PCT/CZ1994/000022 WO1995009243A1 (en) | 1993-09-28 | 1994-09-23 | METHOD OF PRODUCING α,α-TREHALOSE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK69795A3 SK69795A3 (en) | 1996-05-08 |
| SK279610B6 true SK279610B6 (sk) | 1999-01-11 |
Family
ID=5464225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK697-95A SK279610B6 (sk) | 1993-09-28 | 1994-09-23 | Spôsob izolácie kryštalickej alfa, alfa-trehalózy |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0674717A1 (cs) |
| JP (1) | JPH08506248A (cs) |
| CA (1) | CA2150256A1 (cs) |
| CZ (1) | CZ281723B6 (cs) |
| SK (1) | SK279610B6 (cs) |
| WO (1) | WO1995009243A1 (cs) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1053670C (zh) * | 1997-09-18 | 2000-06-21 | 大连理工大学 | 海藻糖的生产方法 |
| WO2013042587A1 (ja) | 2011-09-21 | 2013-03-28 | 株式会社林原 | α，α－トレハロース二含水結晶含有粉末の製造方法 |
| CN102504040A (zh) * | 2011-11-16 | 2012-06-20 | 华南理工大学 | 一种从生产甾醇后的废弃酵母中提取海藻糖的方法 |
| EP3744853A1 (en) * | 2019-05-29 | 2020-12-02 | Ohly GmbH | Trehalose-rich yeast hydrolysate |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04360692A (ja) * | 1991-06-07 | 1992-12-14 | Kanegafuchi Chem Ind Co Ltd | トレハロースの製造方法 |
| JPH0591890A (ja) * | 1991-08-27 | 1993-04-16 | Kanji Matsumoto | トレハロースの製造方法 |
| JPH05292986A (ja) * | 1992-02-21 | 1993-11-09 | Takeda Chem Ind Ltd | トレハロースの製造法 |
| JPH06145186A (ja) * | 1992-11-05 | 1994-05-24 | Nippon Shokuhin Kako Co Ltd | α，α−トレハロースの製造法 |
| BR9400368A (pt) * | 1993-02-02 | 1994-08-23 | Ajinomoto Kk | Processo para isolamento e purificação de trehalose |
-
1993
- 1993-09-28 CZ CZ932025A patent/CZ281723B6/cs not_active IP Right Cessation
-
1994
- 1994-09-23 EP EP94926769A patent/EP0674717A1/en not_active Withdrawn
- 1994-09-23 WO PCT/CZ1994/000022 patent/WO1995009243A1/en not_active Application Discontinuation
- 1994-09-23 CA CA 2150256 patent/CA2150256A1/en not_active Abandoned
- 1994-09-23 SK SK697-95A patent/SK279610B6/sk unknown
- 1994-09-23 JP JP7510039A patent/JPH08506248A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPH08506248A (ja) | 1996-07-09 |
| EP0674717A1 (en) | 1995-10-04 |
| CZ281723B6 (cs) | 1996-12-11 |
| CA2150256A1 (en) | 1995-04-06 |
| SK69795A3 (en) | 1996-05-08 |
| CZ202593A3 (en) | 1996-10-16 |
| WO1995009243A1 (en) | 1995-04-06 |
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