SK106595A3 - Substituted derivatives of 4-phenyl-6-amino-nicotinic acid, mnufacturing process thereof, drugs containing these substances and their use - Google Patents
Substituted derivatives of 4-phenyl-6-amino-nicotinic acid, mnufacturing process thereof, drugs containing these substances and their use Download PDFInfo
- Publication number
- SK106595A3 SK106595A3 SK1065-95A SK106595A SK106595A3 SK 106595 A3 SK106595 A3 SK 106595A3 SK 106595 A SK106595 A SK 106595A SK 106595 A3 SK106595 A3 SK 106595A3
- Authority
- SK
- Slovakia
- Prior art keywords
- amino
- phenyl
- cyano
- carbon atoms
- nicotinic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/803—Processes of preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4430638A DE4430638A1 (de) | 1994-08-29 | 1994-08-29 | Verwendung von substituierten 4-Phenyl-6-amino-nicotinsäurederivaten als Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK106595A3 true SK106595A3 (en) | 1997-01-08 |
Family
ID=6526833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1065-95A SK106595A3 (en) | 1994-08-29 | 1995-08-28 | Substituted derivatives of 4-phenyl-6-amino-nicotinic acid, mnufacturing process thereof, drugs containing these substances and their use |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5670525A (fi) |
| EP (1) | EP0705820A1 (fi) |
| JP (1) | JPH0867670A (fi) |
| KR (1) | KR960007565A (fi) |
| CN (1) | CN1127114A (fi) |
| AU (1) | AU697552B2 (fi) |
| CA (1) | CA2156961A1 (fi) |
| CZ (1) | CZ219895A3 (fi) |
| DE (1) | DE4430638A1 (fi) |
| EE (1) | EE9500059A (fi) |
| FI (1) | FI954007A (fi) |
| HU (1) | HUT74618A (fi) |
| IL (1) | IL115072A (fi) |
| NO (1) | NO308287B1 (fi) |
| NZ (1) | NZ272851A (fi) |
| PL (1) | PL310145A1 (fi) |
| RU (1) | RU2154635C2 (fi) |
| SK (1) | SK106595A3 (fi) |
| TW (1) | TW419464B (fi) |
| ZA (1) | ZA957187B (fi) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999024830A1 (en) * | 1997-11-10 | 1999-05-20 | Bristol-Myers Squibb Company | Method for diagnosing alzheimer's disease |
| DE10059418A1 (de) | 2000-11-30 | 2002-06-20 | Aventis Pharma Gmbh | Ortho, meta-substituierte Bisarylverbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| DE10060807A1 (de) * | 2000-12-07 | 2002-06-20 | Aventis Pharma Gmbh | Ortho, ortho-substituierte stickstoffhaltige Bisarylverbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| DE10110747A1 (de) * | 2001-03-07 | 2002-09-12 | Bayer Ag | Substituierte 2,6-Diamino-3,5-dicyano-4-aryl-pyridine und ihre Verwendung |
| DE10115945A1 (de) | 2001-03-30 | 2002-10-02 | Bayer Ag | Substituierte 2-Carba-3,5-dicyano-4-aryl-6-aminopyridine und ihre Verwendung |
| US20050075359A1 (en) * | 2003-03-14 | 2005-04-07 | Rikako Kono | Large conductance calcium-activated K channel opener |
| AU2006216566A1 (en) * | 2005-02-24 | 2006-08-31 | Janssen Pharmaceutica N.V. | Novel pyridine derivatives as potassium ion channel openers |
| DE102006042143A1 (de) * | 2006-09-08 | 2008-03-27 | Bayer Healthcare Aktiengesellschaft | Neue substituierte Bipyridin-Derivate und ihre Verwendung |
| DE102006056739A1 (de) * | 2006-12-01 | 2008-06-05 | Bayer Healthcare Ag | Substituierte 4-Amino-3,5-dicyano-2-thiopyridine und ihre Verwendung |
| DE102006056740A1 (de) * | 2006-12-01 | 2008-06-05 | Bayer Healthcare Ag | Cyclisch substituierte 3,5-Dicyano-2-thiopyridine und ihre Verwendung |
| DE102007035367A1 (de) | 2007-07-27 | 2009-01-29 | Bayer Healthcare Ag | Substituierte Aryloxazole und ihre Verwendung |
| DE102007036076A1 (de) | 2007-08-01 | 2009-02-05 | Bayer Healthcare Aktiengesellschaft | Dipeptoid-Produgs und ihre Verwendung |
| DE102007061763A1 (de) * | 2007-12-20 | 2009-06-25 | Bayer Healthcare Ag | Substituierte azabicyclische Verbindungen und ihre Verwendung |
| DE102007061764A1 (de) * | 2007-12-20 | 2009-06-25 | Bayer Healthcare Ag | Anellierte Cyanopyridine und ihre Verwendung |
| DE102008013587A1 (de) * | 2008-03-11 | 2009-09-17 | Bayer Schering Pharma Aktiengesellschaft | Heteroaryl-substituierte Dicyanopyridine und ihre Verwendung |
| EP2297104B1 (de) * | 2008-05-29 | 2013-08-07 | Bayer Intellectual Property GmbH | 2-alkoxy-substituierte dicyanopyridine und ihre verwendung |
| DE102008062567A1 (de) | 2008-12-16 | 2010-06-17 | Bayer Schering Pharma Aktiengesellschaft | Dipeptoid-Prodrugs und ihre Verwendung |
| DE102009006602A1 (de) * | 2009-01-29 | 2010-08-05 | Bayer Schering Pharma Aktiengesellschaft | Alkylamino-substituierte Dicyanopyridine und deren Aminosäureester-Prodrugs |
| DE102010030688A1 (de) | 2010-06-30 | 2012-01-05 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Dicyanopyridine und ihre Verwendung |
| US20120058983A1 (en) | 2010-09-02 | 2012-03-08 | Bayer Pharma Aktiengesellschaft | Adenosine A1 agonists for the treatment of glaucoma and ocular hypertension |
| US9056832B2 (en) * | 2010-09-17 | 2015-06-16 | Purdue Pharma L.P. | Pyridine compounds and the users thereof |
-
1994
- 1994-08-29 DE DE4430638A patent/DE4430638A1/de not_active Withdrawn
-
1995
- 1995-07-20 TW TW084107499A patent/TW419464B/zh active
- 1995-08-16 EP EP95112833A patent/EP0705820A1/de not_active Withdrawn
- 1995-08-22 US US08/517,873 patent/US5670525A/en not_active Expired - Fee Related
- 1995-08-23 AU AU30205/95A patent/AU697552B2/en not_active Ceased
- 1995-08-23 PL PL95310145A patent/PL310145A1/xx unknown
- 1995-08-24 JP JP7237915A patent/JPH0867670A/ja active Pending
- 1995-08-25 IL IL11507295A patent/IL115072A/xx not_active IP Right Cessation
- 1995-08-25 FI FI954007A patent/FI954007A/fi unknown
- 1995-08-25 CN CN95116625A patent/CN1127114A/zh active Pending
- 1995-08-25 NZ NZ272851A patent/NZ272851A/en unknown
- 1995-08-25 CA CA002156961A patent/CA2156961A1/en not_active Abandoned
- 1995-08-28 CZ CZ952198A patent/CZ219895A3/cs unknown
- 1995-08-28 RU RU95114449/04A patent/RU2154635C2/ru active
- 1995-08-28 KR KR1019950026840A patent/KR960007565A/ko not_active Application Discontinuation
- 1995-08-28 SK SK1065-95A patent/SK106595A3/sk unknown
- 1995-08-28 HU HU9502520A patent/HUT74618A/hu unknown
- 1995-08-28 EE EE9500059A patent/EE9500059A/xx unknown
- 1995-08-28 ZA ZA957187A patent/ZA957187B/xx unknown
- 1995-08-28 NO NO953367A patent/NO308287B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US5670525A (en) | 1997-09-23 |
| IL115072A (en) | 1999-12-31 |
| CN1127114A (zh) | 1996-07-24 |
| NO953367D0 (no) | 1995-08-28 |
| CA2156961A1 (en) | 1996-03-01 |
| HUT74618A (en) | 1997-01-28 |
| KR960007565A (ko) | 1996-03-22 |
| PL310145A1 (en) | 1996-03-04 |
| HU9502520D0 (en) | 1995-10-30 |
| NO953367L (no) | 1996-03-01 |
| EE9500059A (et) | 1996-04-15 |
| FI954007A0 (fi) | 1995-08-25 |
| TW419464B (en) | 2001-01-21 |
| RU2154635C2 (ru) | 2000-08-20 |
| AU3020595A (en) | 1996-03-14 |
| ZA957187B (en) | 1996-04-17 |
| AU697552B2 (en) | 1998-10-08 |
| NZ272851A (en) | 1997-07-27 |
| IL115072A0 (en) | 1995-12-08 |
| EP0705820A1 (de) | 1996-04-10 |
| FI954007A (fi) | 1996-03-01 |
| JPH0867670A (ja) | 1996-03-12 |
| CZ219895A3 (en) | 1996-03-13 |
| DE4430638A1 (de) | 1996-03-07 |
| NO308287B1 (no) | 2000-08-28 |
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