SI9200386A - Crystallisation of optical isomers of leukotriene antagonists - Google Patents

Crystallisation of optical isomers of leukotriene antagonists Download PDF

Info

Publication number
SI9200386A
SI9200386A SI19929200386A SI9200386A SI9200386A SI 9200386 A SI9200386 A SI 9200386A SI 19929200386 A SI19929200386 A SI 19929200386A SI 9200386 A SI9200386 A SI 9200386A SI 9200386 A SI9200386 A SI 9200386A
Authority
SI
Slovenia
Prior art keywords
alkyl
salt
alkoxy
formula
phenyl
Prior art date
Application number
SI19929200386A
Other languages
English (en)
Slovenian (sl)
Inventor
Robert John Mills
Original Assignee
Smithkline Beecham Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corporation filed Critical Smithkline Beecham Corporation
Publication of SI9200386A publication Critical patent/SI9200386A/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/56Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI19929200386A 1991-12-12 1992-12-14 Crystallisation of optical isomers of leukotriene antagonists SI9200386A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/806,031 US5214201A (en) 1991-12-12 1991-12-12 Crystallization of optical isomers of leukotriene antagonists

Publications (1)

Publication Number Publication Date
SI9200386A true SI9200386A (en) 1993-06-30

Family

ID=25193150

Family Applications (1)

Application Number Title Priority Date Filing Date
SI19929200386A SI9200386A (en) 1991-12-12 1992-12-14 Crystallisation of optical isomers of leukotriene antagonists

Country Status (21)

Country Link
US (1) US5214201A (no)
EP (1) EP0638055A1 (no)
JP (1) JPH07501823A (no)
CN (1) CN1074212A (no)
AP (1) AP371A (no)
AU (1) AU3243993A (no)
BG (1) BG98842A (no)
BR (1) BR9207022A (no)
CA (1) CA2125495A1 (no)
CZ (1) CZ141294A3 (no)
FI (1) FI942746A0 (no)
HU (1) HUT70850A (no)
IL (1) IL104077A0 (no)
MA (1) MA22742A1 (no)
MX (1) MX9207252A (no)
NO (1) NO942187D0 (no)
OA (1) OA10025A (no)
SI (1) SI9200386A (no)
SK (1) SK69094A3 (no)
WO (1) WO1993012054A1 (no)
ZA (1) ZA929677B (no)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4845272A (en) * 1987-07-10 1989-07-04 Kuraray Co., Ltd. Process for the optical resolution of (±)-cis or (±)-trans-permethric acid
IT1217988B (it) * 1988-01-28 1990-03-30 Ind Chimica Profarmaco Spa Procedimento per la risoluzione ottica di un pacemo
US4904822A (en) * 1988-02-19 1990-02-27 Kuraray Co., Ltd. Process for the optical resolution of (+)-2-hydroxy-4-phenylbutanoic acid
IT1226300B (it) * 1988-07-26 1990-12-27 Zambon Spa Processo per la preparazione di intermedi per la sintesi del diltiazem.
CA2018437A1 (en) * 1989-06-14 1990-12-14 James Simpson Frazee Leukotriene antagonists

Also Published As

Publication number Publication date
BR9207022A (pt) 1995-12-12
AP371A (en) 1994-11-10
ZA929677B (en) 1993-10-13
US5214201A (en) 1993-05-25
EP0638055A1 (en) 1995-02-15
HU9401744D0 (en) 1994-09-28
WO1993012054A1 (en) 1993-06-24
MA22742A1 (fr) 1993-07-01
IL104077A0 (en) 1993-05-13
JPH07501823A (ja) 1995-02-23
BG98842A (bg) 1995-05-31
SK69094A3 (en) 1995-03-08
OA10025A (en) 1996-10-14
CZ141294A3 (en) 1995-01-18
EP0638055A4 (en) 1994-10-19
NO942187L (no) 1994-06-10
HUT70850A (en) 1995-11-28
CN1074212A (zh) 1993-07-14
NO942187D0 (no) 1994-06-10
AP9200462A0 (en) 1993-01-31
FI942746A (fi) 1994-06-10
AU3243993A (en) 1993-07-19
FI942746A0 (fi) 1994-06-10
CA2125495A1 (en) 1993-06-24
MX9207252A (es) 1993-07-01

Similar Documents

Publication Publication Date Title
DE69409525T2 (de) Acetamidderivate und ihre verwendung als modifizierungsmittel des verhaltens der verdauung
KR20020067509A (ko) 실질적으로 순수한 비칼루타마이드의 합성시 중간산물을분리하는 방법
US20080031939A1 (en) Process for the preparation of armodafinil
SK4682002A3 (en) Process for preparing a substituted allylamine derivative and the salts thereof
EP1330450B1 (en) Process for the production of r(+)alpha-lipoic acid
JP2546624B2 (ja) 光学的に純粋なアミノアルコールの製造方法
SI9200386A (en) Crystallisation of optical isomers of leukotriene antagonists
JPS6323856A (ja) カルバミン酸または尿素の誘導体、その製造法およびその医薬への応用
US4625054A (en) Process for the resolution of (+)-6-methoxy-α-methyl-2-naphthaleneacetic acid into the corresponding enantiomers
DE69911689T2 (de) Verfahren zur Herstellung von S-Aryl-L-cystein und Derivate
EP0280603A1 (fr) Enantiomères de configuration absolue S de dérivés amide de l'amino-3 quinuclidine, leur procédé de préparation et leur application en thérapeutique
US5288900A (en) Crystallization of optical isomers of leukotriene antagonists using (R)-4-nitro-α-methylbenezenemethonamine
JP2823679B2 (ja) 光学活性2―メチルピペラジンの製造方法
CS261232B2 (en) Method of 1(2-/5-dimethylamino methyl-2(furylmethylthio)ethyl/)amino-1-methylamino-2-nitroethylene production
EP0101379A1 (fr) Benzamides, leurs sels, procédé pour leur préparation et compositions pharmaceutiques les renfermant
JPH10101629A (ja) 光学活性酪酸誘導体の製造方法
ZA200306448B (en) New asymmetric process for the preparation of diaryl-methylpiperazines derivatives and novel asymmetric diarylmethylamines as intermediates.
RU2032681C1 (ru) Способ получения 1-(2-[(5-диметиламинометил-2-фурил) -метилтио]-этил)-амино-1- метиламино-2-нитроэтилена
JPH06107604A (ja) 光学活性1−(4−ハロゲノフェニル)エチルアミンの製造法
JPS59231065A (ja) プロピオン酸誘導体の光学分割方法
EP0581169A1 (en) Optical resolution of threo-2-hydroxy-3-(2-aminophenylthio)-3-(4-methoxyphenyl)-propionic acid
IE65877B1 (en) N-(1-naphthylmethyl)-alpha-loweralkyl-benzylamine and derivatives thereof
JPS5959660A (ja) D−3−アセチルチオ−2−メチルプロピオン酸の取得法
JP2001226330A (ja) 光学活性1−(4−ハロゲノフェニル)エチルアミン類の製造方法