SI3297654T1 - Zdravljenje postbariatrične hipoglikemije z eksendinom(9-39) - Google Patents
Zdravljenje postbariatrične hipoglikemije z eksendinom(9-39)Info
- Publication number
- SI3297654T1 SI3297654T1 SI201631300T SI201631300T SI3297654T1 SI 3297654 T1 SI3297654 T1 SI 3297654T1 SI 201631300 T SI201631300 T SI 201631300T SI 201631300 T SI201631300 T SI 201631300T SI 3297654 T1 SI3297654 T1 SI 3297654T1
- Authority
- SI
- Slovenia
- Prior art keywords
- exendin
- post
- treatment
- bariatric hypoglycemia
- bariatric
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562165743P | 2015-05-22 | 2015-05-22 | |
US201562254175P | 2015-11-11 | 2015-11-11 | |
US201662329850P | 2016-04-29 | 2016-04-29 | |
EP16800621.1A EP3297654B1 (en) | 2015-05-22 | 2016-05-23 | Treatment of post-bariatric hypoglycemia with exendin(9-39) |
PCT/US2016/033837 WO2016191395A1 (en) | 2015-05-22 | 2016-05-23 | Treatment of post-bariatric hypoglycemia with exendin(9-39) |
Publications (1)
Publication Number | Publication Date |
---|---|
SI3297654T1 true SI3297654T1 (sl) | 2021-11-30 |
Family
ID=57393681
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201631362T SI3297653T1 (sl) | 2015-05-22 | 2016-05-23 | Zdravljenje postbariatrične hipoglikemije z antagonisti glp-1 |
SI201631300T SI3297654T1 (sl) | 2015-05-22 | 2016-05-23 | Zdravljenje postbariatrične hipoglikemije z eksendinom(9-39) |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201631362T SI3297653T1 (sl) | 2015-05-22 | 2016-05-23 | Zdravljenje postbariatrične hipoglikemije z antagonisti glp-1 |
Country Status (17)
Country | Link |
---|---|
US (8) | US10639354B2 (sl) |
EP (4) | EP3297653B1 (sl) |
AU (4) | AU2016267057B2 (sl) |
BR (2) | BR112017025000A2 (sl) |
CA (2) | CA3024358A1 (sl) |
CL (2) | CL2017002911A1 (sl) |
CY (2) | CY1124616T1 (sl) |
DK (2) | DK3297654T3 (sl) |
ES (2) | ES2897955T3 (sl) |
HR (2) | HRP20211285T1 (sl) |
HU (2) | HUE055728T2 (sl) |
LT (2) | LT3297654T (sl) |
PL (2) | PL3297653T3 (sl) |
PT (2) | PT3297653T (sl) |
RS (2) | RS62627B1 (sl) |
SI (2) | SI3297653T1 (sl) |
WO (2) | WO2016191395A1 (sl) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK3456340T3 (da) | 2007-01-08 | 2022-03-21 | Univ Pennsylvania | Glp-1-receptorantagonist til brug ved behandling af medfødt hyperinsulisme |
EP3297653B1 (en) | 2015-05-22 | 2021-09-15 | The Board of Trustees of the Leland Stanford Junior University | Treatment of post-bariatric hypoglycemia with glp-1 antagonists |
US10653753B2 (en) | 2016-03-04 | 2020-05-19 | Eiger Biopharmaceuticals, Inc. | Treatment of hyperinsulinemic hypoglycemia with exendin-4 derivatives |
JP2019535734A (ja) | 2016-11-21 | 2019-12-12 | アイガー・バイオファーマシューティカルズ・インコーポレイテッドEiger Biopharmaceuticals, Inc. | エキセンディン(9−39)の緩衝製剤 |
EP3743097A1 (en) * | 2018-01-23 | 2020-12-02 | Xeris Pharmaceuticals, Inc. | Treatment of post-bariatric hypoglycemia using mini-dose stable glucagon |
GB201816639D0 (en) * | 2018-10-12 | 2018-11-28 | Heptares Therapeutics Ltd | GLP-1 Receptor Antagonist |
EP3867266A4 (en) * | 2018-10-15 | 2022-07-13 | Eiger Biopharmaceuticals, Inc. | AVEXITIDE FOR THE TREATMENT OF HYPERINSULINEMIC HYPOGLYCEMIA |
US20220088144A1 (en) * | 2019-01-11 | 2022-03-24 | Universitätsspital Basel | Sglt-2 inhibitors or il-1r antagonists for reduction of hypoglycaemia after bariatric surgery |
WO2024042518A1 (en) * | 2022-08-21 | 2024-02-29 | M. Arkin (1999) Ltd | Glp-1 receptor antagonist and methods of use thereof |
Family Cites Families (52)
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PL176007B1 (pl) | 1992-06-15 | 1999-03-31 | Scios Inc | Nowe pochodne polipeptydu GLP-1 |
US5424286A (en) | 1993-05-24 | 1995-06-13 | Eng; John | Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same |
US20040092443A1 (en) | 1996-08-06 | 2004-05-13 | Yeda Research And Development Co., Ltd | Long-acting exendins and exendin agonists |
DE69739172D1 (de) | 1996-08-08 | 2009-01-29 | Amylin Pharmaceuticals Inc | Regulation gastrointestinaler beweglichkeit |
US6268343B1 (en) | 1996-08-30 | 2001-07-31 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
US7235627B2 (en) | 1996-08-30 | 2007-06-26 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
US6458924B2 (en) | 1996-08-30 | 2002-10-01 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
PT1629849E (pt) | 1997-01-07 | 2013-07-09 | Amylin Pharmaceuticals Llc | Composições farmacêuticas que compreendem exendinas e seus agonistas |
US6004297A (en) | 1998-01-30 | 1999-12-21 | Novo Nordisk A/S | Injection syringe |
US6469021B1 (en) | 1998-12-10 | 2002-10-22 | Agouron Pharmaceuticals, Inc. | Non-peptide antagonists of GLP-1 receptor and methods of use |
EP1140145B2 (en) | 1999-01-14 | 2019-05-15 | Amylin Pharmaceuticals, LLC | Novel exendin agonist formulations and methods of administration thereof |
US6872700B1 (en) | 1999-01-14 | 2005-03-29 | Amylin Pharmaceuticals, Inc. | Methods for glucagon suppression |
US6924264B1 (en) | 1999-04-30 | 2005-08-02 | Amylin Pharmaceuticals, Inc. | Modified exendins and exendin agonists |
US6903074B1 (en) | 1999-06-04 | 2005-06-07 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Neuromedin b and somatostatin receptor agonists |
US6495164B1 (en) | 2000-05-25 | 2002-12-17 | Alkermes Controlled Therapeutics, Inc. I | Preparation of injectable suspensions having improved injectability |
US6479065B2 (en) | 2000-08-10 | 2002-11-12 | Alkermes Controlled Therapeutics, Inc. | Process for the preparation of polymer-based sustained release compositions |
US6824822B2 (en) | 2001-08-31 | 2004-11-30 | Alkermes Controlled Therapeutics Inc. Ii | Residual solvent extraction method and microparticles produced thereby |
SE0004462D0 (sv) | 2000-12-04 | 2000-12-04 | Pharmacia Ab | Novel method and use |
WO2002066062A2 (en) | 2001-02-01 | 2002-08-29 | Drucker Daniel J | Enhancement of glp-2 activity |
US7638598B2 (en) | 2001-04-06 | 2009-12-29 | The Trustees Of The University Of Pennsylvania | ErbB interface peptidomimetics and methods of use thereof |
EP1432430A4 (en) | 2001-08-28 | 2006-05-10 | Lilly Co Eli | PREMIXTURES OF GLP-1 AND BASALINSULIN |
US7378385B2 (en) | 2002-08-08 | 2008-05-27 | University Of Cincinnati | Role for GLP-1 to mediate responses to disparate stressors |
AU2004290862B2 (en) | 2003-11-20 | 2010-06-03 | Novo Nordisk A/S | Propylene glycol-containing peptide formulations which are optimal for production and for use in injection devices |
US8076288B2 (en) | 2004-02-11 | 2011-12-13 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides having glucose lowering activity |
KR20100129799A (ko) | 2004-04-15 | 2010-12-09 | 알케르메스,인코포레이티드 | 중합체 기재 지속적 방출 방법 |
US7456254B2 (en) | 2004-04-15 | 2008-11-25 | Alkermes, Inc. | Polymer-based sustained release device |
DE102004043153B4 (de) * | 2004-09-03 | 2013-11-21 | Philipps-Universität Marburg | Erfindung betreffend GLP-1 und Exendin |
JP5198261B2 (ja) | 2005-06-06 | 2013-05-15 | カムルス エービー | Glp−1類似体製剤 |
CN105056211A (zh) | 2005-08-19 | 2015-11-18 | 安米林药品有限责任公司 | 治疗糖尿病和降低体重的毒蜥外泌肽 |
AU2007267833B2 (en) | 2006-05-26 | 2012-07-26 | Amylin Pharmaceuticals, Llc | Composition and methods for treatment of congestive heart failure |
DK3456340T3 (da) | 2007-01-08 | 2022-03-21 | Univ Pennsylvania | Glp-1-receptorantagonist til brug ved behandling af medfødt hyperinsulisme |
DE102007016811A1 (de) | 2007-04-05 | 2008-10-09 | Tecpharma Licensing Ag | Vorrichtung zur Verabreichung eines fluiden Wirkstoffes aus einer Mehrkammerampulle |
EP2144649B1 (de) | 2007-04-05 | 2011-07-20 | Tecpharma Licensing AG | Verabreichungsvorrichtung mit funktionalem antriebsglied |
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JP5622725B2 (ja) | 2008-06-25 | 2014-11-12 | エンド ファーマスーティカルズ ソリューションズ インコーポレイテッド.Endo Pharmaceuticals Solutionsinc. | エキセナチド及び他のポリペプチド類の持続的送達 |
SI2310042T1 (sl) | 2008-07-08 | 2013-03-29 | Novartis Ag | Uporaba pasireotida za zdravljenje endogene hiperinzulinemične hipoglikemije |
BRPI0918904B8 (pt) | 2008-09-04 | 2021-05-25 | Amylin Pharmaceuticals Inc | formulação pré-misturada fabricada para injeção, seu uso e kit compreendendo a mesma |
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WO2011109787A1 (en) | 2010-03-05 | 2011-09-09 | Conjuchem, Llc | Methods of administering insulinotropic peptides |
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EP3297653B1 (en) | 2015-05-22 | 2021-09-15 | The Board of Trustees of the Leland Stanford Junior University | Treatment of post-bariatric hypoglycemia with glp-1 antagonists |
US10653753B2 (en) | 2016-03-04 | 2020-05-19 | Eiger Biopharmaceuticals, Inc. | Treatment of hyperinsulinemic hypoglycemia with exendin-4 derivatives |
JP2019535734A (ja) | 2016-11-21 | 2019-12-12 | アイガー・バイオファーマシューティカルズ・インコーポレイテッドEiger Biopharmaceuticals, Inc. | エキセンディン(9−39)の緩衝製剤 |
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2016
- 2016-05-23 EP EP16800620.3A patent/EP3297653B1/en active Active
- 2016-05-23 RS RS20211458A patent/RS62627B1/sr unknown
- 2016-05-23 HU HUE16800621A patent/HUE055728T2/hu unknown
- 2016-05-23 CA CA3024358A patent/CA3024358A1/en active Pending
- 2016-05-23 LT LTEPPCT/US2016/033837T patent/LT3297654T/lt unknown
- 2016-05-23 BR BR112017025000-4A patent/BR112017025000A2/pt active Search and Examination
- 2016-05-23 US US15/576,647 patent/US10639354B2/en active Active
- 2016-05-23 HU HUE16800620A patent/HUE057301T2/hu unknown
- 2016-05-23 EP EP16800621.1A patent/EP3297654B1/en active Active
- 2016-05-23 DK DK16800621.1T patent/DK3297654T3/da active
- 2016-05-23 ES ES16800620T patent/ES2897955T3/es active Active
- 2016-05-23 ES ES16800621T patent/ES2887723T3/es active Active
- 2016-05-23 LT LTEPPCT/US2016/033836T patent/LT3297653T/lt unknown
- 2016-05-23 CA CA3024353A patent/CA3024353A1/en active Pending
- 2016-05-23 HR HRP20211285TT patent/HRP20211285T1/hr unknown
- 2016-05-23 AU AU2016267057A patent/AU2016267057B2/en active Active
- 2016-05-23 PT PT16800620T patent/PT3297653T/pt unknown
- 2016-05-23 RS RS20211073A patent/RS62368B1/sr unknown
- 2016-05-23 SI SI201631362T patent/SI3297653T1/sl unknown
- 2016-05-23 PT PT168006211T patent/PT3297654T/pt unknown
- 2016-05-23 US US15/576,646 patent/US10660937B2/en active Active
- 2016-05-23 SI SI201631300T patent/SI3297654T1/sl unknown
- 2016-05-23 HR HRP20211768TT patent/HRP20211768T1/hr unknown
- 2016-05-23 PL PL16800620T patent/PL3297653T3/pl unknown
- 2016-05-23 DK DK16800620.3T patent/DK3297653T3/da active
- 2016-05-23 EP EP21194982.1A patent/EP3978011A1/en active Pending
- 2016-05-23 EP EP21176474.1A patent/EP3936143A1/en active Pending
- 2016-05-23 WO PCT/US2016/033837 patent/WO2016191395A1/en active Application Filing
- 2016-05-23 BR BR112017024997-9A patent/BR112017024997A2/pt active Search and Examination
- 2016-05-23 AU AU2016267052A patent/AU2016267052B2/en active Active
- 2016-05-23 WO PCT/US2016/033836 patent/WO2016191394A1/en active Application Filing
- 2016-05-23 PL PL16800621T patent/PL3297654T3/pl unknown
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2017
- 2017-11-16 CL CL2017002911A patent/CL2017002911A1/es unknown
- 2017-11-16 CL CL2017002913A patent/CL2017002913A1/es unknown
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2020
- 2020-03-09 US US16/813,536 patent/US10993992B2/en active Active
- 2020-03-09 US US16/813,535 patent/US10993991B2/en active Active
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2021
- 2021-04-09 US US17/226,161 patent/US11622995B2/en active Active
- 2021-04-09 US US17/226,164 patent/US11617782B2/en active Active
- 2021-09-01 CY CY20211100779T patent/CY1124616T1/el unknown
- 2021-11-29 CY CY20211101046T patent/CY1125147T1/el unknown
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2022
- 2022-03-22 AU AU2022201973A patent/AU2022201973A1/en active Pending
- 2022-04-14 AU AU2022202506A patent/AU2022202506A1/en active Pending
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2023
- 2023-02-22 US US18/172,543 patent/US20230346890A1/en active Pending
- 2023-02-22 US US18/172,546 patent/US20240000894A1/en active Pending
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