SI2954932T1 - Terapevtska uporaba diaminofenotiazinov - Google Patents

Terapevtska uporaba diaminofenotiazinov

Info

Publication number
SI2954932T1
SI2954932T1 SI200832022T SI200832022T SI2954932T1 SI 2954932 T1 SI2954932 T1 SI 2954932T1 SI 200832022 T SI200832022 T SI 200832022T SI 200832022 T SI200832022 T SI 200832022T SI 2954932 T1 SI2954932 T1 SI 2954932T1
Authority
SI
Slovenia
Prior art keywords
diaminophenothiazines
therapeutic use
therapeutic
Prior art date
Application number
SI200832022T
Other languages
English (en)
Inventor
Claude Michel Wischik
Damon Jude Wischik
John Mervyn David Storey
Charles Robert Harrington
Original Assignee
Wista Laboratories Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wista Laboratories Ltd. filed Critical Wista Laboratories Ltd.
Publication of SI2954932T1 publication Critical patent/SI2954932T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI200832022T 2007-10-03 2008-10-01 Terapevtska uporaba diaminofenotiazinov SI2954932T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96054407P 2007-10-03 2007-10-03
EP15161198.5A EP2954932B1 (en) 2007-10-03 2008-10-01 Therapeutic use of diaminophenothiazines

Publications (1)

Publication Number Publication Date
SI2954932T1 true SI2954932T1 (sl) 2019-01-31

Family

ID=40220337

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200832022T SI2954932T1 (sl) 2007-10-03 2008-10-01 Terapevtska uporaba diaminofenotiazinov
SI200831497T SI2205245T1 (sl) 2007-10-03 2008-10-01 Terapevtska uporaba diaminofenotiazinov

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200831497T SI2205245T1 (sl) 2007-10-03 2008-10-01 Terapevtska uporaba diaminofenotiazinov

Country Status (17)

Country Link
US (3) US9149481B2 (sl)
EP (2) EP2205245B1 (sl)
JP (1) JP5592261B2 (sl)
CN (1) CN101883567B (sl)
AU (1) AU2008306688B2 (sl)
BR (1) BRPI0818182B1 (sl)
CA (2) CA2701075C (sl)
DK (2) DK2205245T3 (sl)
ES (2) ES2701089T3 (sl)
HK (2) HK1140675A1 (sl)
HR (1) HRP20151006T1 (sl)
HU (1) HUE025199T2 (sl)
MY (1) MY161656A (sl)
PL (2) PL2205245T3 (sl)
PT (2) PT2954932T (sl)
SI (2) SI2954932T1 (sl)
WO (1) WO2009044127A1 (sl)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2349322T7 (es) 2006-03-29 2019-10-17 Wista Lab Ltd Sales de 3,7-diamino-10H-fenotiazina y su utilización
HUE025199T2 (en) * 2007-10-03 2016-01-28 Wista Lab Ltd Therapeutic use of diaminophenothiazines
SG185094A1 (en) 2010-04-30 2012-12-28 Prostetta Antiviral Inc Antiviral compounds
US8828986B2 (en) 2011-04-20 2014-09-09 Prosetta Antiviral Inc. Antiviral compounds
CN103379901B (zh) 2010-11-30 2018-04-03 维斯塔实验室有限公司 含有氯化甲基息奥宁的配方
US20120244174A1 (en) 2011-01-31 2012-09-27 Intellect Neurosciences Inc. Treatment of tauopathies
KR101888713B1 (ko) 2011-02-11 2018-08-14 위스타 레보레이토리스 리미티드 페노티아진 디아미늄 염 및 이의 용도
CN102690244A (zh) * 2011-03-22 2012-09-26 中国科学院上海生命科学研究院 调节α-突触核蛋白积聚的物质及其制药用途
US20130315825A1 (en) * 2012-05-03 2013-11-28 Washington University Tricyclic heteroaromatic compounds as alpha-synuclein ligands
CN103864717B (zh) * 2014-04-04 2015-11-11 山东理工大学 一种针状亚甲基白晶体的制备方法
CN103923036B (zh) * 2014-04-24 2015-09-16 山东理工大学 一种棒状亚甲基蓝晶体的制备方法
CN105541756B (zh) * 2015-12-17 2018-02-09 陕西方舟制药有限公司 一种制备1‑(3,7‑双二甲氨基‑吩噻嗪‑10‑基)乙酮的方法
SI3487505T1 (sl) 2016-07-25 2023-10-30 Wista Laboratories Ltd., Dajanje in odmerek diaminofenotiazinov
GB201614834D0 (en) * 2016-09-01 2016-10-19 Wista Lab Ltd Treatment of dementia
KR20210038586A (ko) 2018-07-26 2021-04-07 위스타 레보레이토리스 리미티드 집단에서 디아미노페노티아진(diaminophenothiazines)의 최적 투여량
CN113874078A (zh) 2019-04-05 2021-12-31 Tauc3生物制品有限公司 抗tauc3抗体及其应用
GB201909454D0 (en) 2019-07-01 2019-08-14 Wista Lab Ltd Enhancers
GB201909493D0 (en) 2019-07-01 2019-08-14 Wista Lab Ltd Therapeutic interactions
GB201909506D0 (en) 2019-07-02 2019-08-14 Wista Lab Ltd Synaptopathies
CN111956245A (zh) * 2020-08-27 2020-11-20 复旦大学附属肿瘤医院 术后认知功能障碍预防评估方法,系统和装置
WO2023232764A1 (en) 2022-05-31 2023-12-07 Wista Laboratories Ltd. Treatment of neurodegenerative disorders utilising methylthioninium (mt)-containing compounds
WO2024063700A1 (en) 2022-09-21 2024-03-28 Yin Sze Loh Oral formulation of diaminophenothiazines and methods of making and using the same in the treatment and/or prevention of diseases
WO2024163665A1 (en) * 2023-01-31 2024-08-08 Unlearn.AI, Inc. Systems and methods for prognostic covariate adjustment in logistic regression for randomized controlled trial design

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9022788D0 (en) * 1990-10-19 1990-12-05 Cortecs Ltd Pharmaceutical formulations
DE4140192C2 (de) * 1991-12-05 1996-02-29 Alfatec Pharma Gmbh Sol-gesteuerte Thermokolloidmatrix auf Gelatinebasis für perorale Retardformen
GB9506197D0 (en) * 1995-03-27 1995-05-17 Hoffmann La Roche Inhibition of tau-tau association.
US5972389A (en) 1996-09-19 1999-10-26 Depomed, Inc. Gastric-retentive, oral drug dosage forms for the controlled-release of sparingly soluble drugs and insoluble matter
GB9710699D0 (en) 1997-05-24 1997-07-16 Danbiosyst Uk Gastro-retentive controlled release system
GB0017060D0 (en) * 2000-07-11 2000-08-30 Hunter Fleming Ltd Production, stabilisation and use of reduced forms of pharmaceutical compounds
GB0100119D0 (en) * 2001-01-03 2001-02-14 Univ Aberdeen Materials and methods relating to protein aggregation in neurodegenerative disease
GB0101049D0 (en) * 2001-01-15 2001-02-28 Univ Aberdeen Materials and methods relating to protein aggregation in neurodegenerative disease
GB0106953D0 (en) 2001-03-20 2001-05-09 Univ Aberdeen Neufofibrillary labels
US7410965B2 (en) * 2002-05-29 2008-08-12 Gruenenthal Gmbh Delayed release pharmaceutical composition containing 1-dimethyl-amino-3-(3-methoxyphenyl)-2-methyl-pentan-3-ol
GB0322756D0 (en) 2003-09-29 2003-10-29 Univ Aberdeen Methods of chemical synthesis
CN101084204B (zh) * 2004-09-23 2012-12-05 卫思道制药有限公司 包括亚甲蓝(mtc)在内的二氨基吩噻嗪鎓化合物的化学合成和纯化方法
WO2006091728A2 (en) * 2005-02-24 2006-08-31 The Trustees Of The University Of Pennsylvania Microtubule stabilizing compounds and methods of their use
WO2007056439A1 (en) * 2005-11-08 2007-05-18 Collegium Pharmaceutical, Inc. Salts of methylene blue and its derivatives
US8263589B2 (en) * 2006-03-29 2012-09-11 Wista Laboratories Ltd. Inhibitors of protein aggregation
ES2349322T7 (es) * 2006-03-29 2019-10-17 Wista Lab Ltd Sales de 3,7-diamino-10H-fenotiazina y su utilización
PL2057136T3 (pl) * 2006-07-11 2013-10-31 Wista Lab Ltd Sposoby syntezy i/lub oczyszczania związków diaminofenotiazynowych
PT2167095T (pt) * 2007-06-19 2019-08-06 Wista Lab Ltd Compostos de fenotiazina para o tratamento de comprometimento cognitivo leve
HUE025199T2 (en) * 2007-10-03 2016-01-28 Wista Lab Ltd Therapeutic use of diaminophenothiazines

Also Published As

Publication number Publication date
DK2205245T3 (en) 2015-09-28
HRP20151006T1 (hr) 2015-10-23
BRPI0818182A2 (pt) 2020-06-23
PT2205245E (pt) 2015-10-13
WO2009044127A1 (en) 2009-04-09
HUE025199T2 (en) 2016-01-28
CA3027974A1 (en) 2009-04-09
CA2701075C (en) 2019-02-12
MY161656A (en) 2017-04-28
AU2008306688A1 (en) 2009-04-09
EP2954932B1 (en) 2018-09-19
ES2546819T3 (es) 2015-09-28
DK2954932T3 (en) 2018-12-17
CA2701075A1 (en) 2009-04-09
CA3027974C (en) 2022-03-15
US10188658B2 (en) 2019-01-29
ES2701089T3 (es) 2019-02-20
JP2010540606A (ja) 2010-12-24
AU2008306688B2 (en) 2014-05-22
EP2205245B1 (en) 2015-06-24
CN101883567A (zh) 2010-11-10
EP2954932A1 (en) 2015-12-16
CN101883567B (zh) 2012-12-26
EP2205245A1 (en) 2010-07-14
PL2205245T3 (pl) 2015-12-31
US20190151329A1 (en) 2019-05-23
BRPI0818182B1 (pt) 2021-10-19
JP5592261B2 (ja) 2014-09-17
SI2205245T1 (sl) 2015-10-30
US9149481B2 (en) 2015-10-06
US20160030444A1 (en) 2016-02-04
PL2954932T3 (pl) 2019-04-30
PT2954932T (pt) 2018-12-12
HK1211889A1 (en) 2016-06-03
HK1140675A1 (en) 2010-10-22
US20100290986A1 (en) 2010-11-18

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