SI2806855T1 - Suha praškasta formulacija, ki obsega kortikosteroid in beta-adrenergik za dajanje z inhalacijo - Google Patents

Suha praškasta formulacija, ki obsega kortikosteroid in beta-adrenergik za dajanje z inhalacijo

Info

Publication number
SI2806855T1
SI2806855T1 SI201331186T SI201331186T SI2806855T1 SI 2806855 T1 SI2806855 T1 SI 2806855T1 SI 201331186 T SI201331186 T SI 201331186T SI 201331186 T SI201331186 T SI 201331186T SI 2806855 T1 SI2806855 T1 SI 2806855T1
Authority
SI
Slovenia
Prior art keywords
corticosteroid
adrenergic
inhalation
beta
administration
Prior art date
Application number
SI201331186T
Other languages
English (en)
Inventor
Elisa Monari
Anna Maria Cantarelli
Daniela Cocconi
Irene Pasquali
Original Assignee
Chiesi Farmaceutici S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47715987&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2806855(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farmaceutici S.P.A. filed Critical Chiesi Farmaceutici S.P.A.
Publication of SI2806855T1 publication Critical patent/SI2806855T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0003Details of inhalators; Constructional features thereof with means for dispensing more than one drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
SI201331186T 2012-01-25 2013-01-23 Suha praškasta formulacija, ki obsega kortikosteroid in beta-adrenergik za dajanje z inhalacijo SI2806855T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12152392 2012-01-25
PCT/EP2013/051187 WO2013110632A1 (en) 2012-01-25 2013-01-23 Dry powder formulation comprising a corticosteroid and a beta-adrenergic for administration by inhalation
EP13704372.5A EP2806855B1 (en) 2012-01-25 2013-01-23 Dry powder formulation comprising a corticosteroid and a beta-adrenergic for administration by inhalation

Publications (1)

Publication Number Publication Date
SI2806855T1 true SI2806855T1 (sl) 2018-11-30

Family

ID=47715987

Family Applications (2)

Application Number Title Priority Date Filing Date
SI201332032T SI3412277T1 (sl) 2012-01-25 2013-01-23 Suha praškasta formulacija, ki obsega kortikosteroid in beta-adrenergik za dajanje z inhalacijo
SI201331186T SI2806855T1 (sl) 2012-01-25 2013-01-23 Suha praškasta formulacija, ki obsega kortikosteroid in beta-adrenergik za dajanje z inhalacijo

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI201332032T SI3412277T1 (sl) 2012-01-25 2013-01-23 Suha praškasta formulacija, ki obsega kortikosteroid in beta-adrenergik za dajanje z inhalacijo

Country Status (38)

Country Link
US (3) US10028964B2 (sl)
EP (7) EP3020394A1 (sl)
JP (1) JP6104282B2 (sl)
KR (3) KR101895279B1 (sl)
CN (2) CN105726548B (sl)
AR (1) AR089805A1 (sl)
AU (1) AU2013211656B2 (sl)
BR (1) BR112014017481A8 (sl)
CA (1) CA2862548C (sl)
CL (1) CL2014001966A1 (sl)
CO (1) CO7010836A2 (sl)
CY (1) CY1120684T1 (sl)
DK (5) DK2806855T3 (sl)
EA (2) EA026267B1 (sl)
ES (5) ES2938466T3 (sl)
FI (1) FI3412277T3 (sl)
GE (1) GEP201706767B (sl)
HK (1) HK1200021A1 (sl)
HR (5) HRP20221433T1 (sl)
HU (5) HUE060421T2 (sl)
IL (1) IL233784A0 (sl)
LT (5) LT3412277T (sl)
MA (1) MA35859B1 (sl)
MX (2) MX368199B (sl)
MY (1) MY165888A (sl)
NZ (1) NZ627837A (sl)
PE (1) PE20141703A1 (sl)
PH (1) PH12014501565B1 (sl)
PL (5) PL3527197T3 (sl)
PT (5) PT3527197T (sl)
RS (5) RS63706B1 (sl)
SG (1) SG11201404350PA (sl)
SI (2) SI3412277T1 (sl)
TN (1) TN2014000322A1 (sl)
TW (1) TWI559940B (sl)
UA (1) UA115543C2 (sl)
WO (1) WO2013110632A1 (sl)
ZA (1) ZA201405464B (sl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3412277T (lt) * 2012-01-25 2023-04-25 Chiesi Farmaceutici S.P.A. Sausų miltelių pavidalo vaisto forma, apimanti kortikosteridą ir beta adrenerginį vaistą, skirta įvedimui inhaliacijos būdu
HUE053957T2 (hu) 2013-07-11 2021-08-30 Chiesi Farm Spa Antikolinerg, kortikoszteroid és béta-adrenerg anyagot tartalmazó száraz porkészítmény inhalálással történõ beadásra
UA118861C2 (uk) * 2013-12-06 2019-03-25 Оріон Корпорейшн Спосіб отримання сухих порошкових композицій для інгаляцій
EP3203983A1 (en) 2014-10-08 2017-08-16 Eratech S.r.l. Composition comprising at least one dry powder obtained by spray drying to increase the stability of the formulation
CN109789107B (zh) * 2016-09-29 2021-12-03 广东东阳光药业有限公司 药物组合物
CA3060020A1 (en) * 2017-05-11 2018-11-15 Chiesi Farmaceutici S.P.A. A process for preparing a dry powder formulation comprising an anticholinergic, a corticosteroid and a beta-adrenergic
US11931368B2 (en) 2017-09-29 2024-03-19 Crititech, Inc. Glucocorticoid “nintedanib” particles and their use
EP3910324A1 (en) * 2018-08-07 2021-11-17 Norton (Waterford) Limited Application of raman spectroscopy for the manufacture of inhalation powders
US20210370007A1 (en) 2018-10-30 2021-12-02 Chiesi Farmaceuticl S.p.A. Apparatus to administer drugs to mechanically ventilated patients
JP2022549445A (ja) 2019-09-24 2022-11-25 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ 吸入用乾燥粉末製剤のための新規担体粒子
JP2023539073A (ja) 2020-08-14 2023-09-13 ノートン (ウォーターフォード) リミテッド プロピオン酸フルチカゾンと硫酸アルブテロールの吸入製剤
WO2023117967A1 (en) * 2021-12-21 2023-06-29 Chiesi Farmaceutici S.P.A. Dry powder formulations filled in an inhaler with improved resistance to humidity

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GB9501841D0 (en) * 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
EP1131059B1 (de) * 1998-11-13 2003-03-05 Jago Research Ag Trockenpulver zur inhalation
IT1309592B1 (it) * 1999-03-05 2002-01-24 Chiesi Farma Spa Particelle veicolo modificate da utilizzarsi nella preparazione diformulazioni farmaceutiche sotto forma di polimeri per inalazione e
PE20011227A1 (es) 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
GB0015043D0 (en) 2000-06-21 2000-08-09 Glaxo Group Ltd Medicament dispenser
FI20002215A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit
DE60239639D1 (de) 2002-07-31 2011-05-12 Chiesi Farma Spa Pulverinhalator
JO3102B1 (ar) * 2004-03-17 2017-09-20 Chiesi Framaceutici S P A صيغ صيدلانية لوسائل استنشاق بها مسحوق جاف تشتمل على مكون فعال بقوة منخفضة الجرعة
ES2257152B1 (es) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
EP1944018A1 (en) * 2007-01-10 2008-07-16 CHIESI FARMACEUTICI S.p.A. Micronised particles of low-dosage strength active agents for powder formulations for inhalation
EP1982709A1 (en) 2007-04-19 2008-10-22 CHIESI FARMACEUTICI S.p.A. Use of a composition comprising formoterol and beclomethasone dipropionate for the prevention or treatment of an acute condition of asthma
WO2010097188A1 (en) * 2009-02-25 2010-09-02 Chiesi Farmaceutici S.P.A. Inhalation particles comprising a salt of carmoterol and a corticosteroid
WO2010131486A1 (en) * 2009-05-15 2010-11-18 Shin Nippon Biomedical Laboratories, Ltd. Intranasal pharmaceutical compositions with improved pharmacokinetics
GB0914240D0 (en) 2009-08-14 2009-09-30 Breath Ltd Steroid solvates
DK2482799T3 (da) * 2009-10-02 2014-09-01 Chiesi Farma Spa Farmaceutiske aerosolformuleringer af formoterol og beclometasondipropionat
MX336414B (es) * 2010-04-01 2016-01-19 Chiesi Farma Spa Proceso de preparacion de particulas portadoras para polvos secos para inhalacion.
WO2011131663A1 (en) * 2010-04-21 2011-10-27 Chiesi Farmaceutici S.P.A. "process for providing particles with reduced electrostatic charges"
LT3412277T (lt) * 2012-01-25 2023-04-25 Chiesi Farmaceutici S.P.A. Sausų miltelių pavidalo vaisto forma, apimanti kortikosteridą ir beta adrenerginį vaistą, skirta įvedimui inhaliacijos būdu
HUE053957T2 (hu) * 2013-07-11 2021-08-30 Chiesi Farm Spa Antikolinerg, kortikoszteroid és béta-adrenerg anyagot tartalmazó száraz porkészítmény inhalálással történõ beadásra

Also Published As

Publication number Publication date
CN105726548A (zh) 2016-07-06
EP3527196B1 (en) 2022-09-07
TW201334810A (zh) 2013-09-01
US10946029B2 (en) 2021-03-16
CN104080444A (zh) 2014-10-01
EA031566B1 (ru) 2019-01-31
CN105726548B (zh) 2019-05-14
BR112014017481A2 (pt) 2017-06-13
IL233784A0 (en) 2014-09-30
EP3412277A1 (en) 2018-12-12
AR089805A1 (es) 2014-09-17
HUE040525T2 (hu) 2019-03-28
KR101786586B1 (ko) 2017-10-18
MY165888A (en) 2018-05-18
DK2806855T3 (en) 2018-09-03
NZ627837A (en) 2016-04-29
EP3020394A1 (en) 2016-05-18
KR20150089093A (ko) 2015-08-04
PL3412277T3 (pl) 2023-06-19
ES2928688T3 (es) 2022-11-22
MA35859B1 (fr) 2014-12-01
EP3527196A1 (en) 2019-08-21
EP3527199B1 (en) 2022-09-07
HK1200021A1 (en) 2015-07-31
AU2013211656A1 (en) 2014-07-24
KR20170116234A (ko) 2017-10-18
ZA201405464B (en) 2015-12-23
RS63952B1 (sr) 2023-02-28
PH12014501565A1 (en) 2014-10-08
LT2806855T (lt) 2018-10-10
CO7010836A2 (es) 2014-07-31
CL2014001966A1 (es) 2014-11-14
BR112014017481A8 (pt) 2021-06-15
CY1120684T1 (el) 2019-12-11
EP2806855A1 (en) 2014-12-03
WO2013110632A1 (en) 2013-08-01
ES2929807T3 (es) 2022-12-01
CA2862548A1 (en) 2013-08-01
SG11201404350PA (en) 2014-08-28
RS57637B1 (sr) 2018-11-30
RS63759B1 (sr) 2022-12-30
HUE060421T2 (hu) 2023-02-28
EP3527199A1 (en) 2019-08-21
EP3527198A1 (en) 2019-08-21
DK3527196T3 (da) 2022-10-24
UA115543C2 (uk) 2017-11-27
LT3527197T (lt) 2022-11-25
HRP20230147T1 (hr) 2023-03-31
DK3527199T3 (da) 2022-10-24
PH12014501565B1 (en) 2014-10-08
ES2683254T3 (es) 2018-09-25
HRP20221433T1 (hr) 2023-01-06
GEP201706767B (en) 2017-11-10
EA201491281A1 (ru) 2014-12-30
US10028964B2 (en) 2018-07-24
KR20140114374A (ko) 2014-09-26
MX2014008631A (es) 2014-08-21
MX355729B (es) 2018-04-27
PL3527197T3 (pl) 2022-11-21
DK3412277T3 (da) 2023-02-20
PT2806855T (pt) 2018-09-28
CN104080444B (zh) 2017-06-20
TWI559940B (en) 2016-12-01
EP3527197A1 (en) 2019-08-21
MX368199B (es) 2019-09-24
JP6104282B2 (ja) 2017-03-29
PT3527199T (pt) 2022-11-08
EP2806855B1 (en) 2018-07-11
HRP20221432T1 (hr) 2023-01-06
LT3527199T (lt) 2022-12-12
SI3412277T1 (sl) 2023-03-31
EA026267B1 (ru) 2017-03-31
EA201690187A1 (ru) 2016-05-31
LT3527196T (lt) 2022-11-25
PL3527196T3 (pl) 2022-11-21
HUE060402T2 (hu) 2023-02-28
PT3527197T (pt) 2022-10-26
US20150164915A1 (en) 2015-06-18
FI3412277T3 (fi) 2023-03-23
ES2929137T3 (es) 2022-11-25
CA2862548C (en) 2020-07-07
EP3527197B1 (en) 2022-09-07
PT3527196T (pt) 2022-10-18
RS63706B1 (sr) 2022-11-30
US20130189324A1 (en) 2013-07-25
HRP20221431T1 (hr) 2023-01-06
DK3527197T3 (da) 2022-10-24
AU2013211656B2 (en) 2017-07-13
EP3412277B1 (en) 2022-12-14
PE20141703A1 (es) 2014-11-24
ES2938466T3 (es) 2023-04-11
RS63761B1 (sr) 2022-12-30
HUE061566T2 (hu) 2023-07-28
HUE060705T2 (hu) 2023-04-28
KR101560288B1 (ko) 2015-10-14
US8778402B2 (en) 2014-07-15
PT3412277T (pt) 2023-02-14
JP2015508416A (ja) 2015-03-19
TN2014000322A1 (en) 2015-12-21
PL3527199T3 (pl) 2022-12-12
PL2806855T3 (pl) 2018-12-31
HRP20181550T1 (hr) 2018-11-30
LT3412277T (lt) 2023-04-25
KR101895279B1 (ko) 2018-09-05
US20180296573A1 (en) 2018-10-18

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