SI2627334T1 - Sestavki za uporabo pri zdravljenju virusnih infekcij - Google Patents

Sestavki za uporabo pri zdravljenju virusnih infekcij

Info

Publication number
SI2627334T1
SI2627334T1 SI201130489T SI201130489T SI2627334T1 SI 2627334 T1 SI2627334 T1 SI 2627334T1 SI 201130489 T SI201130489 T SI 201130489T SI 201130489 T SI201130489 T SI 201130489T SI 2627334 T1 SI2627334 T1 SI 2627334T1
Authority
SI
Slovenia
Prior art keywords
compositions
treatment
viral infections
infections
viral
Prior art date
Application number
SI201130489T
Other languages
English (en)
Slovenian (sl)
Inventor
Shanta Bantia
Pravin L. Kotian
Yarlagadda S. Babu
Original Assignee
Biocryst Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocryst Pharmaceuticals, Inc. filed Critical Biocryst Pharmaceuticals, Inc.
Publication of SI2627334T1 publication Critical patent/SI2627334T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/06Heterocyclic radicals
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI201130489T 2010-10-15 2011-10-14 Sestavki za uporabo pri zdravljenju virusnih infekcij SI2627334T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US39352210P 2010-10-15 2010-10-15
US201161492054P 2011-06-01 2011-06-01
PCT/US2011/056421 WO2012051570A1 (en) 2010-10-15 2011-10-14 Methods and compositions for inhibition of polymerase
EP11833515.7A EP2627334B1 (en) 2010-10-15 2011-10-14 Compositions for use in the treatment of viral infections

Publications (1)

Publication Number Publication Date
SI2627334T1 true SI2627334T1 (sl) 2015-08-31

Family

ID=45938737

Family Applications (2)

Application Number Title Priority Date Filing Date
SI201130489T SI2627334T1 (sl) 2010-10-15 2011-10-14 Sestavki za uporabo pri zdravljenju virusnih infekcij
SI201131383T SI2898885T1 (en) 2010-10-15 2011-10-14 Pyrrolopyrimidine derivatives for use in the treatment of viral infections

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI201131383T SI2898885T1 (en) 2010-10-15 2011-10-14 Pyrrolopyrimidine derivatives for use in the treatment of viral infections

Country Status (23)

Country Link
US (5) US20130331404A1 (enExample)
EP (3) EP3345605B1 (enExample)
JP (2) JP5902698B2 (enExample)
KR (1) KR101850925B1 (enExample)
CN (1) CN103429245B (enExample)
AU (2) AU2011315902B2 (enExample)
BR (1) BR112013009029B1 (enExample)
CA (1) CA2813783C (enExample)
CY (1) CY1119880T1 (enExample)
DK (2) DK2627334T3 (enExample)
ES (2) ES2657687T3 (enExample)
HR (2) HRP20150487T1 (enExample)
HU (1) HUE036387T2 (enExample)
IL (1) IL225672B (enExample)
LT (1) LT2898885T (enExample)
MX (1) MX348759B (enExample)
PL (2) PL2898885T3 (enExample)
PT (2) PT2898885T (enExample)
RS (2) RS56870B1 (enExample)
RU (3) RU2599013C2 (enExample)
SI (2) SI2627334T1 (enExample)
SM (2) SMT201800064T1 (enExample)
WO (1) WO2012051570A1 (enExample)

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TWI698444B (zh) 2014-10-29 2020-07-11 美商基利科學股份有限公司 製備核糖苷的方法
CN104513249B (zh) * 2014-12-26 2016-08-31 苏州明锐医药科技有限公司 抗埃博拉病毒药物bcx4430的制备方法
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CN110869028B (zh) 2017-03-14 2023-01-20 吉利德科学公司 治疗猫冠状病毒感染的方法
KR20190141747A (ko) 2017-05-01 2019-12-24 길리애드 사이언시즈, 인코포레이티드 (S)-2-에틸부틸 2-(((S)-(((2R,3S,4R,5R)-5-(4-아미노피롤로[2,1-f] [1,2,4]트리아진-7-일)-5-시아노-3,4-디히드록시테트라히드로푸란-2-일)메톡시)(페녹시) 포스포릴)아미노)프로파노에이트의 결정질 형태
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JP7482250B2 (ja) 2020-04-06 2024-05-13 ギリアード サイエンシーズ, インコーポレイテッド 1’-シアノ置換カルバヌクレオシド類似体の吸入製剤
WO2021207386A1 (en) * 2020-04-07 2021-10-14 Biocryst Pharmaceuticals, Inc. Methods, compositions, and dosing regimens for treatment of sars-cov-2 infections
PL4157272T3 (pl) 2020-05-29 2025-10-20 Gilead Sciences, Inc. Remdesiwir do leczenia zakażeń wirusowych
JP2023531524A (ja) 2020-06-24 2023-07-24 ギリアード サイエンシーズ, インコーポレイテッド 1’-シアノヌクレオシド類似体及びその使用
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KR102871928B1 (ko) * 2021-06-25 2025-10-20 전남대학교 산학협력단 지방분해효소 억제제를 포함하는 rna 바이러스 감염증 예방 또는 치료용 약제학적 조성물
EP4360629A4 (en) * 2021-06-25 2024-11-06 Industry Foundation of Chonnam National University PHARMACEUTICAL COMPOSITION COMPRISING A LIPASE INHIBITOR FOR THE TREATMENT OF RNA VIRAL INFECTIONS
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Also Published As

Publication number Publication date
DK2898885T3 (en) 2018-02-05
SMT201500148B (it) 2015-09-07
PT2627334E (pt) 2015-07-07
ES2536831T3 (es) 2015-05-29
US10022375B2 (en) 2018-07-17
LT2898885T (lt) 2018-02-26
AU2017200471A1 (en) 2017-02-23
RU2718690C2 (ru) 2020-04-13
MX348759B (es) 2017-06-28
EP3345605A1 (en) 2018-07-11
RU2599013C2 (ru) 2016-10-10
RU2016134401A3 (enExample) 2020-01-24
RS54072B1 (sr) 2015-10-30
RU2020111042A (ru) 2021-09-17
HRP20150487T1 (hr) 2015-08-28
EP2627334A4 (en) 2014-04-16
US20170042901A1 (en) 2017-02-16
RU2013121794A (ru) 2014-11-20
BR112013009029A2 (pt) 2018-06-19
HK1257363A1 (en) 2019-10-18
IL225672B (en) 2019-02-28
CY1119880T1 (el) 2018-06-27
MX2013003938A (es) 2013-07-05
HK1212914A1 (en) 2016-06-24
CA2813783C (en) 2019-01-22
CN103429245A (zh) 2013-12-04
JP5902698B2 (ja) 2016-04-13
IL225672A0 (en) 2013-06-27
AU2017200471B2 (en) 2018-04-12
US20150051230A1 (en) 2015-02-19
ES2657687T3 (es) 2018-03-06
BR112013009029B1 (pt) 2021-06-29
JP2013544788A (ja) 2013-12-19
SI2898885T1 (en) 2018-03-30
SMT201800064T1 (it) 2018-03-08
CA2813783A1 (en) 2012-04-19
US20130331404A1 (en) 2013-12-12
KR101850925B1 (ko) 2018-04-20
PT2898885T (pt) 2018-02-05
AU2011315902B2 (en) 2016-11-17
US11173159B2 (en) 2021-11-16
US20180360836A1 (en) 2018-12-20
RS56870B1 (sr) 2018-04-30
US9492452B2 (en) 2016-11-15
US20220040190A1 (en) 2022-02-10
EP2627334A1 (en) 2013-08-21
EP2627334B1 (en) 2015-04-29
DK2627334T3 (en) 2015-05-18
HRP20180220T1 (hr) 2018-03-09
WO2012051570A1 (en) 2012-04-19
EP2898885B1 (en) 2017-11-22
PL2627334T3 (pl) 2015-08-31
US10420769B2 (en) 2019-09-24
JP2016135790A (ja) 2016-07-28
CN103429245B (zh) 2016-10-05
KR20140040676A (ko) 2014-04-03
AU2011315902A1 (en) 2013-05-30
RU2016134401A (ru) 2018-12-10
US20190374544A1 (en) 2019-12-12
EP3345605B1 (en) 2019-11-20
PL2898885T3 (pl) 2018-04-30
HUE036387T2 (hu) 2018-07-30
EP2898885A1 (en) 2015-07-29

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