SI2465523T1 - FVIII-derivirani peptidi in njihova uporaba pri toleriranju hemofilikov - Google Patents

FVIII-derivirani peptidi in njihova uporaba pri toleriranju hemofilikov

Info

Publication number
SI2465523T1
SI2465523T1 SI201030819T SI201030819T SI2465523T1 SI 2465523 T1 SI2465523 T1 SI 2465523T1 SI 201030819 T SI201030819 T SI 201030819T SI 201030819 T SI201030819 T SI 201030819T SI 2465523 T1 SI2465523 T1 SI 2465523T1
Authority
SI
Slovenia
Prior art keywords
fviii
derived peptides
tolerising
haemophiliacs
tolerising haemophiliacs
Prior art date
Application number
SI201030819T
Other languages
English (en)
Inventor
David Wraith
Original Assignee
Apitope International Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40834163&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2465523(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Apitope International Nv filed Critical Apitope International Nv
Publication of SI2465523T1 publication Critical patent/SI2465523T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI201030819T 2009-05-18 2010-05-17 FVIII-derivirani peptidi in njihova uporaba pri toleriranju hemofilikov SI2465523T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0908515.0A GB0908515D0 (en) 2009-05-18 2009-05-18 Peptide
EP12159740.5A EP2465523B1 (en) 2009-05-18 2010-05-17 FVIII-derived peptides and their use in tolerising haemophiliacs

Publications (1)

Publication Number Publication Date
SI2465523T1 true SI2465523T1 (sl) 2015-02-27

Family

ID=40834163

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201030819T SI2465523T1 (sl) 2009-05-18 2010-05-17 FVIII-derivirani peptidi in njihova uporaba pri toleriranju hemofilikov

Country Status (31)

Country Link
US (1) US8703705B2 (sl)
EP (2) EP2432494A2 (sl)
JP (1) JP5784009B2 (sl)
KR (1) KR101673889B1 (sl)
CN (1) CN102458445B (sl)
AU (1) AU2010250957B2 (sl)
BR (1) BRPI1012845A2 (sl)
CA (1) CA2762020C (sl)
CL (1) CL2011002893A1 (sl)
CO (1) CO6460780A2 (sl)
CY (1) CY1115832T1 (sl)
DK (1) DK2465523T3 (sl)
EA (1) EA027229B1 (sl)
EC (1) ECSP11011540A (sl)
ES (1) ES2525448T3 (sl)
GB (1) GB0908515D0 (sl)
HK (1) HK1173358A1 (sl)
HR (1) HRP20141182T1 (sl)
IL (1) IL216199A (sl)
MX (1) MX2011012270A (sl)
MY (1) MY168207A (sl)
NZ (2) NZ613713A (sl)
PL (1) PL2465523T3 (sl)
PT (1) PT2465523E (sl)
RS (1) RS53671B1 (sl)
SG (2) SG190573A1 (sl)
SI (1) SI2465523T1 (sl)
SM (1) SMT201400186B (sl)
UA (1) UA110921C2 (sl)
WO (1) WO2010133834A2 (sl)
ZA (1) ZA201108446B (sl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010325787B2 (en) 2009-12-06 2016-05-12 Bioverativ Therapeutics Inc. Factor VIII-Fc chimeric and hybrid polypeptides, and methods of use thereof
DK2917232T3 (en) * 2012-11-12 2017-06-12 Apitope Int Nv FACTOR VIII DERIVATIVE PEPTIDES TO USE FOR TREATMENT OF HAEMOPHYL A
GB201314052D0 (en) 2013-08-06 2013-09-18 Apitope Int Nv Peptides
PE20231949A1 (es) 2015-10-30 2023-12-05 Spark Therapeutics Inc VARIANTES DEL FACTOR VIII REDUCIDO CON CpG, COMPOSICIONES Y METODOS Y USOS PARA EL TRATAMIENTO DE TRASTORNOS DE LA HEMOSTASIA
JP2021523878A (ja) 2018-05-18 2021-09-09 バイオベラティブ セラピューティクス インコーポレイテッド 血友病ａを処置する方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU229377B1 (hu) 2000-08-21 2013-11-28 Apitope Technology Bristol Ltd Tolerogén humán peptidek
US20040096456A1 (en) * 2000-12-01 2004-05-20 Conti-Fine Bianca M Method to treat hemophilia
WO2002098454A2 (en) * 2001-05-31 2002-12-12 D. Collen Research Foundation Vzw Onderwijsen Navorsing Campus Gasthuisberg K.U. Leuven Recombinant molecules with reduced immunogenicity, methods and intermediates for obtaining them and their use in pharmaceutical compositions and diagnostic tools
WO2002096454A1 (en) 2001-05-31 2002-12-05 D. Collen Research Foundation Vzw Recombinant molecules with reduced immunogenicity, methods and intermediates for obtaining them and their use in pharmaceutical compositions and diagnostic tools
MXPA04010061A (es) * 2002-04-18 2004-12-13 Merck Patent Gmbh Factor viii modificado.
GB0723712D0 (en) * 2007-12-04 2008-01-16 Apitope Technology Bristol Ltd Peptides
GB0801513D0 (en) * 2008-01-28 2008-03-05 Circassia Ltd Peptides from factor VIII

Also Published As

Publication number Publication date
US20120121625A1 (en) 2012-05-17
KR101673889B1 (ko) 2016-11-08
WO2010133834A2 (en) 2010-11-25
EA027229B1 (ru) 2017-07-31
BRPI1012845A2 (pt) 2016-10-11
EP2465523B1 (en) 2014-10-01
EA201171430A1 (ru) 2012-05-30
HK1173358A1 (en) 2013-05-16
CA2762020A1 (en) 2010-11-25
MX2011012270A (es) 2011-12-12
WO2010133834A3 (en) 2011-02-24
UA110921C2 (uk) 2016-03-10
ECSP11011540A (es) 2012-01-31
EP2465523A1 (en) 2012-06-20
GB0908515D0 (en) 2009-06-24
JP5784009B2 (ja) 2015-09-24
AU2010250957B2 (en) 2015-01-15
RS53671B1 (en) 2015-04-30
CN102458445B (zh) 2014-06-11
US8703705B2 (en) 2014-04-22
CN102458445A (zh) 2012-05-16
IL216199A (en) 2015-11-30
SG176138A1 (en) 2011-12-29
AU2010250957A1 (en) 2011-12-01
PT2465523E (pt) 2014-12-09
NZ596300A (en) 2013-08-30
JP2012527440A (ja) 2012-11-08
IL216199A0 (en) 2012-01-31
NZ613713A (en) 2014-10-31
KR20120023023A (ko) 2012-03-12
HRP20141182T1 (hr) 2015-02-13
CY1115832T1 (el) 2017-01-25
SMT201400186B (it) 2015-01-15
EP2432494A2 (en) 2012-03-28
DK2465523T3 (en) 2014-12-15
ES2525448T3 (es) 2014-12-23
PL2465523T3 (pl) 2015-03-31
MY168207A (en) 2018-10-15
CA2762020C (en) 2018-08-28
CO6460780A2 (es) 2012-06-15
SG190573A1 (en) 2013-06-28
ZA201108446B (en) 2013-01-30
CL2011002893A1 (es) 2012-08-17

Similar Documents

Publication Publication Date Title
HK1258140A1 (zh) 經修飾鬆弛素多肽及其用途
IL218753A0 (en) Protein arrays and uses thereof
EP2383283A4 (en) NOGGIN PEPTIDE AND ITS USE
HK1145506A1 (en) Peptides and their use
EP2474555A4 (en) PEPTIDE DERIVED FROM WNT10 AND USE THEREOF
GB0916578D0 (en) Polypeptides and uses thereof
HRP20140344T1 (en) Fviii peptides and their use in tolerising haemophiliacs
GB0916576D0 (en) Polypeptides and uses thereof
HRP20150195T1 (en) Peptides and their use
GB0702022D0 (en) Peptides and their use
IL199618A0 (en) Novel antibodies and their use in diagnostic methods
HK1168363A1 (en) Novel peptide and use thereof
PL2465523T3 (pl) FVIII Peptydy i ich zastosowanie w indukcji tolerancji u chorych na hemofilię
GB0905790D0 (en) Novel polypeptides and use thereof
EP2450374A4 (en) PEPTIDE AND ITS USE
EP2415780A4 (en) SYNTHETIC PEPTIDE AND USES THEREOF
GB201001170D0 (en) Novel peptides and their use in therepy and diagnosis
GB0800502D0 (en) Peptides and their uses
GB0918461D0 (en) Improvements in and relating to analysis
GB0800701D0 (en) F10 Polypeptides and uses thereof