UA110921C2 - Пептид - Google Patents

Пептид

Info

Publication number
UA110921C2
UA110921C2 UAA201114970A UAA201114970A UA110921C2 UA 110921 C2 UA110921 C2 UA 110921C2 UA A201114970 A UAA201114970 A UA A201114970A UA A201114970 A UAA201114970 A UA A201114970A UA 110921 C2 UA110921 C2 UA 110921C2
Authority
UA
Ukraine
Prior art keywords
peptide
relates
hemophilia
antibody
inhibitor
Prior art date
Application number
UAA201114970A
Other languages
English (en)
Inventor
Девід Рейт
Original Assignee
Епітоп Інтернешнл Нв
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40834163&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA110921(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Епітоп Інтернешнл Нв filed Critical Епітоп Інтернешнл Нв
Publication of UA110921C2 publication Critical patent/UA110921C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Винахід належить до пептиду, який походить від фактора FVIII, а саме до пептиду, що складається з послідовності EDNIMVTFRNQASR. Винахід також стосується застосування такого пептиду для попередження або пригнічення утворення антитіла-інгібітору при гемофілії та/або при набутій гемофілії.
UAA201114970A 2009-05-18 2010-05-17 Пептид UA110921C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0908515.0A GB0908515D0 (en) 2009-05-18 2009-05-18 Peptide
PCT/GB2010/000997 WO2010133834A2 (en) 2009-05-18 2010-05-17 Peptide

Publications (1)

Publication Number Publication Date
UA110921C2 true UA110921C2 (uk) 2016-03-10

Family

ID=40834163

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201114970A UA110921C2 (uk) 2009-05-18 2010-05-17 Пептид

Country Status (31)

Country Link
US (1) US8703705B2 (uk)
EP (2) EP2432494A2 (uk)
JP (1) JP5784009B2 (uk)
KR (1) KR101673889B1 (uk)
CN (1) CN102458445B (uk)
AU (1) AU2010250957B2 (uk)
BR (1) BRPI1012845A2 (uk)
CA (1) CA2762020C (uk)
CL (1) CL2011002893A1 (uk)
CO (1) CO6460780A2 (uk)
CY (1) CY1115832T1 (uk)
DK (1) DK2465523T3 (uk)
EA (1) EA027229B1 (uk)
EC (1) ECSP11011540A (uk)
ES (1) ES2525448T3 (uk)
GB (1) GB0908515D0 (uk)
HK (1) HK1173358A1 (uk)
HR (1) HRP20141182T1 (uk)
IL (1) IL216199A (uk)
MX (1) MX2011012270A (uk)
MY (1) MY168207A (uk)
NZ (2) NZ596300A (uk)
PL (1) PL2465523T3 (uk)
PT (1) PT2465523E (uk)
RS (1) RS53671B1 (uk)
SG (2) SG176138A1 (uk)
SI (1) SI2465523T1 (uk)
SM (1) SMT201400186B (uk)
UA (1) UA110921C2 (uk)
WO (1) WO2010133834A2 (uk)
ZA (1) ZA201108446B (uk)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ703153A (en) 2009-12-06 2015-02-27 Biogen Idec Hemophilia Inc Factor viii-fc chimeric and hybrid polypeptides, and methods of use thereof
PT2917232T (pt) * 2012-11-12 2017-06-09 Apitope Int Nv Péptidos derivados do fator viii para uso no tratamento da hemofilia a
GB201314052D0 (en) * 2013-08-06 2013-09-18 Apitope Int Nv Peptides
PE20231949A1 (es) 2015-10-30 2023-12-05 Spark Therapeutics Inc VARIANTES DEL FACTOR VIII REDUCIDO CON CpG, COMPOSICIONES Y METODOS Y USOS PARA EL TRATAMIENTO DE TRASTORNOS DE LA HEMOSTASIA

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL215187B1 (pl) * 2000-08-21 2013-11-29 Apitope Technology Bristol Ltd Peptyd tolerogenny, kompozycja farmaceutyczna zawierajaca ten peptyd, peptyd lub kompozycja farmaceutyczna do podawania i zastosowanie peptydu tolerogennego
US20040096456A1 (en) * 2000-12-01 2004-05-20 Conti-Fine Bianca M Method to treat hemophilia
WO2002096454A1 (en) 2001-05-31 2002-12-05 D. Collen Research Foundation Vzw Recombinant molecules with reduced immunogenicity, methods and intermediates for obtaining them and their use in pharmaceutical compositions and diagnostic tools
AU2002312660A1 (en) * 2001-05-31 2002-12-16 D. Collen Research Foundation Vzw Onderwijsen Navorsing Campus Gasthuisberg K.U. Leuven Recombinant molecules with reduced immunogenicity, methods and intermediates for obtaining them and their use in pharmaceutical compositions and diagnostic tools
BR0308860A (pt) * 2002-04-18 2005-01-04 Merck Patent Gmbh Fator viii modificado
GB0723712D0 (en) * 2007-12-04 2008-01-16 Apitope Technology Bristol Ltd Peptides
GB0801513D0 (en) * 2008-01-28 2008-03-05 Circassia Ltd Peptides from factor VIII

Also Published As

Publication number Publication date
NZ613713A (en) 2014-10-31
PT2465523E (pt) 2014-12-09
AU2010250957B2 (en) 2015-01-15
MX2011012270A (es) 2011-12-12
CN102458445B (zh) 2014-06-11
CO6460780A2 (es) 2012-06-15
DK2465523T3 (en) 2014-12-15
JP5784009B2 (ja) 2015-09-24
GB0908515D0 (en) 2009-06-24
ECSP11011540A (es) 2012-01-31
EA027229B1 (ru) 2017-07-31
SMT201400186B (it) 2015-01-15
HRP20141182T1 (hr) 2015-02-13
PL2465523T3 (pl) 2015-03-31
AU2010250957A1 (en) 2011-12-01
RS53671B1 (en) 2015-04-30
CA2762020A1 (en) 2010-11-25
EP2432494A2 (en) 2012-03-28
MY168207A (en) 2018-10-15
US8703705B2 (en) 2014-04-22
WO2010133834A2 (en) 2010-11-25
NZ596300A (en) 2013-08-30
ZA201108446B (en) 2013-01-30
BRPI1012845A2 (pt) 2016-10-11
SG176138A1 (en) 2011-12-29
CY1115832T1 (el) 2017-01-25
IL216199A (en) 2015-11-30
ES2525448T3 (es) 2014-12-23
KR101673889B1 (ko) 2016-11-08
SI2465523T1 (sl) 2015-02-27
CN102458445A (zh) 2012-05-16
HK1173358A1 (en) 2013-05-16
EP2465523B1 (en) 2014-10-01
CA2762020C (en) 2018-08-28
US20120121625A1 (en) 2012-05-17
EP2465523A1 (en) 2012-06-20
SG190573A1 (en) 2013-06-28
EA201171430A1 (ru) 2012-05-30
JP2012527440A (ja) 2012-11-08
IL216199A0 (en) 2012-01-31
CL2011002893A1 (es) 2012-08-17
WO2010133834A3 (en) 2011-02-24
KR20120023023A (ko) 2012-03-12

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