SI2220033T1 - Kristalna oblika tigeciklin hidroklorida - Google Patents
Kristalna oblika tigeciklin hidrokloridaInfo
- Publication number
- SI2220033T1 SI2220033T1 SI200831397T SI200831397T SI2220033T1 SI 2220033 T1 SI2220033 T1 SI 2220033T1 SI 200831397 T SI200831397 T SI 200831397T SI 200831397 T SI200831397 T SI 200831397T SI 2220033 T1 SI2220033 T1 SI 2220033T1
- Authority
- SI
- Slovenia
- Prior art keywords
- crystalline forms
- tigecycline hydrochloride
- tigecycline
- hydrochloride
- crystalline
- Prior art date
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title 1
- FPZLLRFZJZRHSY-HJYUBDRYSA-N tigecycline Chemical compound C([C@H]1C2)C3=C(N(C)C)C=C(NC(=O)CNC(C)(C)C)C(O)=C3C(=O)C1=C(O)[C@@]1(O)[C@@H]2[C@H](N(C)C)C(O)=C(C(N)=O)C1=O FPZLLRFZJZRHSY-HJYUBDRYSA-N 0.000 title 1
- 229960004089 tigecycline Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
- C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
- C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
- C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
- C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07120732 | 2007-11-14 | ||
| PCT/EP2008/065398 WO2009062963A1 (en) | 2007-11-14 | 2008-11-12 | Crystalline forms of tigecycline hydrochloride |
| EP08849962.9A EP2220033B1 (en) | 2007-11-14 | 2008-11-12 | Crystalline forms of tigecycline hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2220033T1 true SI2220033T1 (sl) | 2015-07-31 |
Family
ID=39186791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200831397T SI2220033T1 (sl) | 2007-11-14 | 2008-11-12 | Kristalna oblika tigeciklin hidroklorida |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8252946B2 (enExample) |
| EP (1) | EP2220033B1 (enExample) |
| JP (1) | JP5574967B2 (enExample) |
| CN (1) | CN101861300B (enExample) |
| CA (1) | CA2704536C (enExample) |
| ES (1) | ES2532880T3 (enExample) |
| IL (1) | IL205451A0 (enExample) |
| SI (1) | SI2220033T1 (enExample) |
| WO (1) | WO2009062963A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102285898A (zh) * | 2011-06-29 | 2011-12-21 | 赵军旭 | 替加环素盐酸盐的晶型及其制备方法 |
| CN106431963B (zh) * | 2015-08-13 | 2019-03-05 | 江苏豪森药业集团有限公司 | 替加环素的新晶型及其制备方法 |
| WO2017219994A1 (zh) * | 2016-06-22 | 2017-12-28 | 山东亨利医药科技有限责任公司 | 9-氨基甲基取代的四环素类化合物的晶型及其制备方法 |
| CN111060641B (zh) * | 2019-12-27 | 2020-10-23 | 瀚晖制药有限公司 | 一种注射用替加环素中9-硝基米诺环素的检测方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5675030A (en) * | 1994-11-16 | 1997-10-07 | American Cyanamid Company | Method for selective extracting a 7-(hydrogen or substituted amino)-9- (substituted glycyl) amido!-6-demethyl-6-deoxytetracycline compound |
| UA83266C2 (en) * | 2003-12-08 | 2008-06-25 | Уайет | Oxazole derivatives of tetracyclines |
| AR057033A1 (es) * | 2005-05-27 | 2007-11-14 | Wyeth Corp | Tigeciclina y metodos para preparar 9-nitrominociclina |
| AR057032A1 (es) | 2005-05-27 | 2007-11-14 | Wyeth Corp | Tigeciclina y metodos de preparacion |
| AR057649A1 (es) | 2005-05-27 | 2007-12-12 | Wyeth Corp | Formas solidas cristalinas de tigeciclina y metodos para preparar las mismas |
| AR057324A1 (es) * | 2005-05-27 | 2007-11-28 | Wyeth Corp | Tigeciclina y metodos para preparar 9-aminominociclina |
| AR057034A1 (es) * | 2005-05-27 | 2007-11-14 | Wyeth Corp | Metodos para purificar tigeciclina |
| DE202007019460U1 (de) | 2006-04-24 | 2012-10-24 | Teva Pharmaceutical Industries Ltd. | Kristalline Tigecyclin-Formen |
| WO2008066935A2 (en) | 2006-11-29 | 2008-06-05 | Teva Pharmaceutical Industries Ltd. | Crystalline forms of tigecycline and processes for preparation thereof |
| EP2178827A1 (en) | 2007-06-21 | 2010-04-28 | Sandoz AG | Crystalline solid forms |
| CN101386582A (zh) * | 2007-09-14 | 2009-03-18 | 上海来益生物药物研究开发中心有限责任公司 | 替加环素盐及其制备方法 |
-
2008
- 2008-11-12 US US12/742,706 patent/US8252946B2/en active Active
- 2008-11-12 EP EP08849962.9A patent/EP2220033B1/en active Active
- 2008-11-12 CA CA2704536A patent/CA2704536C/en not_active Expired - Fee Related
- 2008-11-12 WO PCT/EP2008/065398 patent/WO2009062963A1/en not_active Ceased
- 2008-11-12 CN CN200880116248.7A patent/CN101861300B/zh active Active
- 2008-11-12 JP JP2010533564A patent/JP5574967B2/ja active Active
- 2008-11-12 ES ES08849962.9T patent/ES2532880T3/es active Active
- 2008-11-12 SI SI200831397T patent/SI2220033T1/sl unknown
-
2010
- 2010-04-29 IL IL205451A patent/IL205451A0/en active IP Right Grant
-
2012
- 2012-07-17 US US13/550,665 patent/US20130012481A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009062963A1 (en) | 2009-05-22 |
| CA2704536A1 (en) | 2009-05-22 |
| IL205451A0 (en) | 2010-12-30 |
| CN101861300A (zh) | 2010-10-13 |
| US20110105772A1 (en) | 2011-05-05 |
| US8252946B2 (en) | 2012-08-28 |
| EP2220033B1 (en) | 2014-12-17 |
| CN101861300B (zh) | 2014-07-09 |
| US20130012481A1 (en) | 2013-01-10 |
| ES2532880T3 (es) | 2015-04-01 |
| CA2704536C (en) | 2017-04-25 |
| JP2011503142A (ja) | 2011-01-27 |
| EP2220033A1 (en) | 2010-08-25 |
| JP5574967B2 (ja) | 2014-08-20 |
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