SI1849470T1 - Zdravilo proti raku, ki vsebuje alfa,alfa,alfa-trifluorotimidin in zaviralec timidin-fosforilaze - Google Patents

Zdravilo proti raku, ki vsebuje alfa,alfa,alfa-trifluorotimidin in zaviralec timidin-fosforilaze

Info

Publication number
SI1849470T1
SI1849470T1 SI200632192T SI200632192T SI1849470T1 SI 1849470 T1 SI1849470 T1 SI 1849470T1 SI 200632192 T SI200632192 T SI 200632192T SI 200632192 T SI200632192 T SI 200632192T SI 1849470 T1 SI1849470 T1 SI 1849470T1
Authority
SI
Slovenia
Prior art keywords
alpha
trifluorothymidine
anticancer drug
drug containing
phosphorylase inhibitor
Prior art date
Application number
SI200632192T
Other languages
English (en)
Inventor
Tomohiro Emura
Akira Mita
Original Assignee
Taiho Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36740357&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1849470(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US11/042,059 external-priority patent/US7799783B2/en
Application filed by Taiho Pharmaceutical Co., Ltd. filed Critical Taiho Pharmaceutical Co., Ltd.
Publication of SI1849470T1 publication Critical patent/SI1849470T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
SI200632192T 2005-01-26 2006-01-25 Zdravilo proti raku, ki vsebuje alfa,alfa,alfa-trifluorotimidin in zaviralec timidin-fosforilaze SI1849470T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11/042,059 US7799783B2 (en) 2005-01-26 2005-01-26 Method of administrating an anticancer drug containing α, α, α-trifluorothymidine and thymidine phosphorylase inhibitor
JP2005165156 2005-06-06
PCT/JP2006/301097 WO2006080327A1 (ja) 2005-01-26 2006-01-25 α，α，α－トリフルオロチミジンとチミジンホスホリラーゼ阻害剤とを配合した抗癌剤
EP06712292.9A EP1849470B2 (en) 2005-01-26 2006-01-25 Anticancer drug containing alpha, alpha, alpha-trifluorothymidine and thymidine phosphorylase inhibitor

Publications (1)

Publication Number Publication Date
SI1849470T1 true SI1849470T1 (sl) 2017-10-30

Family

ID=36740357

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200632192T SI1849470T1 (sl) 2005-01-26 2006-01-25 Zdravilo proti raku, ki vsebuje alfa,alfa,alfa-trifluorotimidin in zaviralec timidin-fosforilaze

Country Status (19)

Country Link
EP (1) EP1849470B2 (sl)
JP (1) JP5576591B2 (sl)
KR (1) KR101468216B1 (sl)
AU (1) AU2006209547C1 (sl)
CA (1) CA2594713A1 (sl)
CY (2) CY1119393T1 (sl)
DK (1) DK1849470T4 (sl)
ES (1) ES2630002T3 (sl)
FI (1) FI1849470T4 (sl)
HU (2) HUE033306T2 (sl)
LT (2) LT1849470T (sl)
LU (1) LUC00036I2 (sl)
NL (1) NL300889I2 (sl)
PL (1) PL1849470T3 (sl)
PT (1) PT1849470T (sl)
RU (1) RU2394581C2 (sl)
SI (1) SI1849470T1 (sl)
TW (1) TWI362265B (sl)
WO (1) WO2006080327A1 (sl)

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DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
SI1849470T1 (sl) 2005-01-26 2017-10-30 Taiho Pharmaceutical Co., Ltd. Zdravilo proti raku, ki vsebuje alfa,alfa,alfa-trifluorotimidin in zaviralec timidin-fosforilaze
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102007011485A1 (de) 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
JP5852309B2 (ja) * 2007-04-25 2016-02-03 サイクラセル リミテッド 増殖性疾患を治療するためのサパシタビンの使用
BRPI0906467C1 (pt) 2008-01-25 2021-05-25 Gruenenthal Gmbh forma de dosagem farmacêutica com formato exterior modificado resistente à ruptura e com liberação controlada
WO2009135680A1 (en) 2008-05-09 2009-11-12 Grünenthal GmbH Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step
CA2723944A1 (en) * 2008-05-15 2009-11-19 Jan Balzarini Anti-cancer combination therapy
EP2456427B1 (en) 2009-07-22 2015-03-04 Grünenthal GmbH Hot-melt extruded controlled release dosage form
CN102639118B (zh) 2009-07-22 2015-07-29 格吕伦塔尔有限公司 氧化稳定的抗干扰剂型
WO2012028318A1 (en) 2010-09-02 2012-03-08 Grünenthal GmbH Tamper resistant dosage form comprising an anionic polymer
EP2611426B1 (en) 2010-09-02 2014-06-25 Grünenthal GmbH Tamper resistant dosage form comprising inorganic salt
DK2736495T3 (da) 2011-07-29 2017-11-13 Gruenenthal Gmbh Misbrugsbestandig tablet som tilvejebringer øjeblikkelig frigivelse af lægemiddel
HUE034710T2 (hu) 2011-07-29 2018-02-28 Gruenenthal Gmbh Visszaéléssel szemben ellenálló, azonnali hatóanyagfelszabadulást biztosító tabletta
RS56911B1 (sr) 2011-08-16 2018-05-31 Taiho Pharmaceutical Co Ltd Antitumorni agens i postupak predviđanja terapijskog efekta za pacijente sa kolorektalnim kancerom sa kras-mutacijom
TWI503122B (zh) 2012-02-15 2015-10-11 Taiho Pharmaceutical Co Ltd Oral administration of pharmaceutical compositions
TWI526210B (zh) * 2012-02-15 2016-03-21 Taiho Pharmaceutical Co Ltd Oral pharmaceutical composition
CA2864949A1 (en) 2012-02-28 2013-09-06 Grunenthal Gmbh Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
EP2829611A4 (en) 2012-03-14 2015-12-02 Nisshin Pharma Inc SULFURAMINOUS-SUSTAINABLE COMPOSITION
WO2013156453A1 (en) 2012-04-18 2013-10-24 Grünenthal GmbH Tamper resistant and dose-dumping resistant pharmaceutical dosage form
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
CA2872526A1 (en) 2012-05-16 2013-11-21 Novartis Ag Dosage regimen for a pi-3 kinase inhibitor
AU2014245147B2 (en) * 2013-03-27 2017-08-31 Taiho Pharmaceutical Co., Ltd. Antitumor agent including low-dose irinotecan hydrochloride hydrate
SI2979701T1 (sl) * 2013-03-27 2021-02-26 Taiho Pharmaceutical Co., Ltd. Ptotitumorsko sredstvo z irinotekan hidroklorid hidratom
TWI595879B (zh) * 2013-05-17 2017-08-21 Taiho Pharmaceutical Co Ltd Prediction of therapeutic effect in patients with colorectal cancer with TK1 protein hyperactivity
EP3003279A1 (en) 2013-05-29 2016-04-13 Grünenthal GmbH Tamper-resistant dosage form containing one or more particles
AU2014273226B2 (en) 2013-05-29 2019-06-27 Grunenthal Gmbh Tamper resistant dosage form with bimodal release profile
KR20160031526A (ko) 2013-07-12 2016-03-22 그뤼넨탈 게엠베하 에틸렌-비닐 아세테이트 중합체를 함유하는 템퍼 내성 투여형
EP4201424A1 (en) 2013-09-06 2023-06-28 Taiho Pharmaceutical Co., Ltd. Antitumor agent and antitumor effect enhancer
EP3073994A1 (en) 2013-11-26 2016-10-05 Grünenthal GmbH Preparation of a powdery pharmaceutical composition by means of cryo-milling
AU2015261060A1 (en) 2014-05-12 2016-11-03 Grunenthal Gmbh Tamper resistant immediate release capsule formulation comprising Tapentadol
CN106456550A (zh) 2014-05-26 2017-02-22 格吕伦塔尔有限公司 避免乙醇剂量倾泻的多颗粒
CA2983642A1 (en) 2015-04-24 2016-10-27 Grunenthal Gmbh Tamper-resistant dosage form with immediate release and resistance against solvent extraction
US10842750B2 (en) 2015-09-10 2020-11-24 Grünenthal GmbH Protecting oral overdose with abuse deterrent immediate release formulations
KR102281961B1 (ko) 2016-01-08 2021-07-26 다이호야쿠힌고교 가부시키가이샤 면역 조절제를 함유하는 항종양제 및 항종양 효과 증강제
WO2017135412A1 (ja) 2016-02-05 2017-08-10 大鵬薬品工業株式会社 重度腎機能障害を有する癌患者に対する治療方法
EP3730935A4 (en) 2017-12-22 2022-02-23 Taiho Pharmaceutical Co., Ltd. METHOD OF DETECTING ANALOGUES OF TRIFLURIDIN AND/OR TIPIRACIL
US10866219B2 (en) 2017-12-22 2020-12-15 Taiho Pharmaceutical Co., Ltd. Method for detecting trifluridine- and/or tipiracil-related substance
US10816517B2 (en) 2018-01-05 2020-10-27 Taiho Pharmaceutical Co., Ltd. Method for detecting trifluridine-related substance by high-performance liquid chromatography
WO2019135405A1 (ja) 2018-01-05 2019-07-11 大鵬薬品工業株式会社 トリフルリジン由来の類縁物質の検出方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2191340C (en) * 1995-03-29 2001-04-17 Shingo Yano Uracil derivatives, and antitumor effect potentiator and antitumor agent containing the same
PT884051E (pt) * 1996-09-24 2005-03-31 Taiho Pharmaceutical Co Ltd Inibidores de metasteses cancerosas contendo derivados de uracilo
SI1849470T1 (sl) 2005-01-26 2017-10-30 Taiho Pharmaceutical Co., Ltd. Zdravilo proti raku, ki vsebuje alfa,alfa,alfa-trifluorotimidin in zaviralec timidin-fosforilaze

Also Published As

Publication number Publication date
CY2017029I1 (el) 2018-02-14
TWI362265B (en) 2012-04-21
LTPA2017024I1 (lt) 2017-08-10
LUC00036I1 (sl) 2017-10-02
DK1849470T4 (en) 2024-04-02
EP1849470A4 (en) 2010-12-08
HUE033306T2 (hu) 2017-11-28
AU2006209547C1 (en) 2022-04-07
HUS1700032I1 (hu) 2017-09-28
EP1849470A1 (en) 2007-10-31
AU2006209547B2 (en) 2011-05-26
JPWO2006080327A1 (ja) 2008-06-19
LUC00036I2 (sl) 2017-12-01
LT1849470T (lt) 2017-07-25
CY1119393T1 (el) 2018-02-14
RU2007132181A (ru) 2009-03-10
CY2017029I2 (el) 2018-02-14
KR101468216B1 (ko) 2014-12-03
EP1849470B2 (en) 2024-03-20
NL300889I1 (nl) 2017-08-14
LTC1849470I2 (lt) 2019-10-25
RU2394581C2 (ru) 2010-07-20
PL1849470T3 (pl) 2017-11-30
PT1849470T (pt) 2017-09-22
TW200637562A (en) 2006-11-01
JP5576591B2 (ja) 2014-08-20
AU2006209547A1 (en) 2006-08-03
CA2594713A1 (en) 2006-08-03
WO2006080327A1 (ja) 2006-08-03
DK1849470T3 (en) 2017-08-14
NL300889I2 (nl) 2018-01-16
KR20070104559A (ko) 2007-10-26
FI1849470T4 (fi) 2024-03-22
ES2630002T3 (es) 2017-08-17
EP1849470B1 (en) 2017-06-21

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