NL300889I1 - Trifluridine in combinatie met tipiracil of een zout van tipiracil, zoals tipiracilhydrochloride - Google Patents

Trifluridine in combinatie met tipiracil of een zout van tipiracil, zoals tipiracilhydrochloride

Info

Publication number
NL300889I1
NL300889I1 NL300889C NL300889C NL300889I1 NL 300889 I1 NL300889 I1 NL 300889I1 NL 300889 C NL300889 C NL 300889C NL 300889 C NL300889 C NL 300889C NL 300889 I1 NL300889 I1 NL 300889I1
Authority
NL
Netherlands
Prior art keywords
tipiracil
trifluridine
salt
combination
hydrochloride
Prior art date
Application number
NL300889C
Other languages
English (en)
Other versions
NL300889I2 (nl
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36740357&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL300889(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US11/042,059 external-priority patent/US7799783B2/en
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of NL300889I1 publication Critical patent/NL300889I1/nl
Publication of NL300889I2 publication Critical patent/NL300889I2/nl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL300889C 2005-01-26 2017-08-08 Trifluridine in combinatie met tipiracilhydrochloride NL300889I2 (nl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/042,059 US7799783B2 (en) 2005-01-26 2005-01-26 Method of administrating an anticancer drug containing α, α, α-trifluorothymidine and thymidine phosphorylase inhibitor
JP2005165156 2005-06-06
PCT/JP2006/301097 WO2006080327A1 (ja) 2005-01-26 2006-01-25 α，α，α－トリフルオロチミジンとチミジンホスホリラーゼ阻害剤とを配合した抗癌剤

Publications (2)

Publication Number Publication Date
NL300889I1 true NL300889I1 (nl) 2017-08-14
NL300889I2 NL300889I2 (nl) 2018-01-16

Family

ID=36740357

Family Applications (1)

Application Number Title Priority Date Filing Date
NL300889C NL300889I2 (nl) 2005-01-26 2017-08-08 Trifluridine in combinatie met tipiracilhydrochloride

Country Status (19)

Country Link
EP (1) EP1849470B2 (nl)
JP (1) JP5576591B2 (nl)
KR (1) KR101468216B1 (nl)
AU (1) AU2006209547C1 (nl)
CA (1) CA2594713A1 (nl)
CY (2) CY1119393T1 (nl)
DK (1) DK1849470T4 (nl)
ES (1) ES2630002T5 (nl)
FI (1) FI1849470T4 (nl)
HU (2) HUE033306T2 (nl)
LT (2) LT1849470T (nl)
LU (1) LUC00036I2 (nl)
NL (1) NL300889I2 (nl)
PL (1) PL1849470T5 (nl)
PT (1) PT1849470T (nl)
RU (1) RU2394581C2 (nl)
SI (1) SI1849470T2 (nl)
TW (1) TWI362265B (nl)
WO (1) WO2006080327A1 (nl)

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DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
RU2394581C2 (ru) 2005-01-26 2010-07-20 Тайхо Фармасьютикал Ко., Лтд. ПРОТИВОРАКОВОЕ ЛЕКАРСТВЕННОЕ СРЕДСТВО, СОДЕРЖАЩЕЕ α,α,α-ТРИФТОРТИМИДИН И ИНГИБИТОР ТИМИДИНФОСФОРИЛАЗЫ
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102007011485A1 (de) 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
EP2148676B1 (en) * 2007-04-25 2016-05-25 Cyclacel Limited Use of sapacitabine to treat proliferative disease
BRPI0906467C1 (pt) 2008-01-25 2021-05-25 Gruenenthal Gmbh forma de dosagem farmacêutica com formato exterior modificado resistente à ruptura e com liberação controlada
KR101690094B1 (ko) 2008-05-09 2016-12-27 그뤼넨탈 게엠베하 분무 응결 단계의 사용하에 중간 분말 제형 및 최종 고체 제형을 제조하는 방법
EP2303283A2 (en) * 2008-05-15 2011-04-06 Katholieke Universiteit Leuven K.U. Leuven R&D Anti-cancer combination therapy
PE20121067A1 (es) 2009-07-22 2012-09-05 Gruenenthal Chemie Forma de dosificacion de liberacion controlada extruida por fusion en caliente
WO2011009604A1 (en) 2009-07-22 2011-01-27 Grünenthal GmbH Oxidation-stabilized tamper-resistant dosage form
WO2012028319A1 (en) 2010-09-02 2012-03-08 Grünenthal GmbH Tamper resistant dosage form comprising inorganic salt
CA2808541C (en) 2010-09-02 2019-01-08 Gruenenthal Gmbh Tamper resistant dosage form comprising an anionic polymer
KR20140053158A (ko) 2011-07-29 2014-05-07 그뤼넨탈 게엠베하 즉시 약물 방출을 제공하는 탬퍼-저항성 정제
AR087360A1 (es) 2011-07-29 2014-03-19 Gruenenthal Gmbh Tableta a prueba de manipulacion que proporciona liberacion de farmaco inmediato
KR101693090B1 (ko) * 2011-08-16 2017-01-04 다이호야쿠힌고교 가부시키가이샤 Kras 유전자 변이형의 결장 직장암 환자에 대한 항종양제 및 치료 효과 예측 방법
TWI503122B (zh) 2012-02-15 2015-10-11 Taiho Pharmaceutical Co Ltd Oral administration of pharmaceutical compositions
TWI526210B (zh) * 2012-02-15 2016-03-21 Taiho Pharmaceutical Co Ltd Oral pharmaceutical composition
CA2864949A1 (en) 2012-02-28 2013-09-06 Grunenthal Gmbh Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
TWI585206B (zh) 2012-03-14 2017-06-01 Nisshin Pharma Inc A method for producing a composition containing a sulfur-containing amino acid
JP6282261B2 (ja) 2012-04-18 2018-02-21 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 不正使用防止および過量放出防止医薬剤形
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
SG11201406550QA (en) * 2012-05-16 2014-11-27 Novartis Ag Dosage regimen for a pi-3 kinase inhibitor
ES2702911T3 (es) * 2013-03-27 2019-03-06 Taiho Pharmaceutical Co Ltd Agente antitumoral que incluye una baja dosis de clorhidrato de irinotecán hidratado
RU2657604C2 (ru) * 2013-03-27 2018-06-14 Тайхо Фармасьютикал Ко., Лтд. Противоопухолевый агент, включающий гидрат гидрохлорида иринотекана
NZ714014A (en) * 2013-05-17 2017-06-30 Taiho Pharmaceutical Co Ltd Therapeutic effect prediction method for colorectal cancer patient in whom expression of tk1 protein has increased
CA2913209A1 (en) 2013-05-29 2014-12-04 Grunenthal Gmbh Tamper resistant dosage form with bimodal release profile
EP3003279A1 (en) 2013-05-29 2016-04-13 Grünenthal GmbH Tamper-resistant dosage form containing one or more particles
AU2014289187B2 (en) 2013-07-12 2019-07-11 Grunenthal Gmbh Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
PL3042669T3 (pl) 2013-09-06 2023-06-26 Taiho Pharmaceutical Co., Ltd. Środek przeciwnowotworowy i środek wzmacniający efekt przeciwnowotworowy
MX371372B (es) 2013-11-26 2020-01-28 Gruenenthal Gmbh Preparacion de una composicion farmaceutica en polvo por medio de criomolienda.
CA2947786A1 (en) 2014-05-12 2015-11-19 Grunenthal Gmbh Tamper resistant immediate release capsule formulation comprising tapentadol
WO2015181059A1 (en) 2014-05-26 2015-12-03 Grünenthal GmbH Multiparticles safeguarded against ethanolic dose-dumping
JP2018517676A (ja) 2015-04-24 2018-07-05 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 即時放出および溶媒抽出に対する耐性を有する改変防止製剤
WO2017042325A1 (en) 2015-09-10 2017-03-16 Grünenthal GmbH Protecting oral overdose with abuse deterrent immediate release formulations
US11612653B2 (en) * 2016-01-08 2023-03-28 Taiho Pharmaceutical Co., Ltd. Anti-tumor agent containing immunomodulator, and antitumor effect potentiator
NZ745113A (en) * 2016-02-05 2021-12-24 Taiho Pharmaceutical Co Ltd Method for treating cancer patients with severe renal impairment
WO2019124544A1 (ja) 2017-12-22 2019-06-27 大鵬薬品工業株式会社 トリフルリジン及び／又はチピラシル由来の類縁物質の検出方法
US10866219B2 (en) 2017-12-22 2020-12-15 Taiho Pharmaceutical Co., Ltd. Method for detecting trifluridine- and/or tipiracil-related substance
WO2019135405A1 (ja) 2018-01-05 2019-07-11 大鵬薬品工業株式会社 トリフルリジン由来の類縁物質の検出方法
US10816517B2 (en) 2018-01-05 2020-10-27 Taiho Pharmaceutical Co., Ltd. Method for detecting trifluridine-related substance by high-performance liquid chromatography

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2203683T3 (es) * 1995-03-29 2004-04-16 Taiho Pharmaceutical Company Limited Derivados de uracilo, agentes de potencializacion de efecto antitumoral y agente antitumoral que incluye estos derivados.
KR100284413B1 (ko) * 1996-09-24 2001-03-02 고바야시 유키오 우라실 유도체를 함유하는 암전이 억제제유도체
RU2394581C2 (ru) 2005-01-26 2010-07-20 Тайхо Фармасьютикал Ко., Лтд. ПРОТИВОРАКОВОЕ ЛЕКАРСТВЕННОЕ СРЕДСТВО, СОДЕРЖАЩЕЕ α,α,α-ТРИФТОРТИМИДИН И ИНГИБИТОР ТИМИДИНФОСФОРИЛАЗЫ

Also Published As

Publication number Publication date
PT1849470T (pt) 2017-09-22
JPWO2006080327A1 (ja) 2008-06-19
RU2007132181A (ru) 2009-03-10
TWI362265B (en) 2012-04-21
AU2006209547C1 (en) 2022-04-07
JP5576591B2 (ja) 2014-08-20
WO2006080327A1 (ja) 2006-08-03
DK1849470T4 (en) 2024-04-02
FI1849470T4 (fi) 2024-03-22
PL1849470T3 (pl) 2017-11-30
PL1849470T5 (pl) 2024-06-10
KR20070104559A (ko) 2007-10-26
LUC00036I2 (nl) 2017-12-01
KR101468216B1 (ko) 2014-12-03
HUS1700032I1 (hu) 2017-09-28
SI1849470T1 (sl) 2017-10-30
DK1849470T3 (en) 2017-08-14
EP1849470A4 (en) 2010-12-08
LTC1849470I2 (lt) 2019-10-25
CY2017029I2 (el) 2018-02-14
CA2594713A1 (en) 2006-08-03
EP1849470B1 (en) 2017-06-21
EP1849470A1 (en) 2007-10-31
CY1119393T1 (el) 2018-02-14
TW200637562A (en) 2006-11-01
NL300889I2 (nl) 2018-01-16
LUC00036I1 (nl) 2017-10-02
HUE033306T2 (hu) 2017-11-28
LT1849470T (lt) 2017-07-25
RU2394581C2 (ru) 2010-07-20
EP1849470B2 (en) 2024-03-20
ES2630002T5 (es) 2024-09-19
LTPA2017024I1 (lt) 2017-08-10
SI1849470T2 (sl) 2024-05-31
CY2017029I1 (el) 2018-02-14
ES2630002T3 (es) 2017-08-17
AU2006209547B2 (en) 2011-05-26
AU2006209547A1 (en) 2006-08-03

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