SI1656410T1 - Postopek za pripravo funkcionaliziranih polimerov iz polimer alkoholov - Google Patents
Postopek za pripravo funkcionaliziranih polimerov iz polimer alkoholovInfo
- Publication number
- SI1656410T1 SI1656410T1 SI200431425T SI200431425T SI1656410T1 SI 1656410 T1 SI1656410 T1 SI 1656410T1 SI 200431425 T SI200431425 T SI 200431425T SI 200431425 T SI200431425 T SI 200431425T SI 1656410 T1 SI1656410 T1 SI 1656410T1
- Authority
- SI
- Slovenia
- Prior art keywords
- preparing functionalized
- functionalized polymers
- polymer alcohols
- polymer
- alcohols
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
- C08G65/33331—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing imide group
- C08G65/33337—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing imide group cyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/30—Post-polymerisation treatment, e.g. recovery, purification, drying
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/321—Polymers modified by chemical after-treatment with inorganic compounds
- C08G65/322—Polymers modified by chemical after-treatment with inorganic compounds containing hydrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/321—Polymers modified by chemical after-treatment with inorganic compounds
- C08G65/323—Polymers modified by chemical after-treatment with inorganic compounds containing halogens
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
- C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
- C08G65/3322—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof acyclic
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
- C08G65/33303—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing amino group
- C08G65/33306—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing amino group acyclic
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
- C08G65/33365—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing cyano group
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
- C08G65/48—Polymers modified by chemical after-treatment
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G2650/28—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
- C08G2650/38—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type containing oxygen in addition to the ether group
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/02—Applications for biomedical use
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48958303P | 2003-07-22 | 2003-07-22 | |
EP04778925A EP1656410B1 (en) | 2003-07-22 | 2004-07-22 | Method for preparing functionalized polymers from polymer alcohols |
PCT/US2004/023633 WO2005010075A2 (en) | 2003-07-22 | 2004-07-22 | Method for preparing functionalized polymers from polymer alcohols |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1656410T1 true SI1656410T1 (sl) | 2010-07-30 |
Family
ID=34102900
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200431425T SI1656410T1 (sl) | 2003-07-22 | 2004-07-22 | Postopek za pripravo funkcionaliziranih polimerov iz polimer alkoholov |
Country Status (18)
Country | Link |
---|---|
US (5) | US8604159B2 (sl) |
EP (1) | EP1656410B1 (sl) |
KR (1) | KR101131411B1 (sl) |
AT (1) | ATE460451T1 (sl) |
AU (1) | AU2004259327B2 (sl) |
CA (1) | CA2533702C (sl) |
CY (1) | CY1110169T1 (sl) |
DE (1) | DE602004025949D1 (sl) |
DK (1) | DK1656410T3 (sl) |
ES (1) | ES2341960T3 (sl) |
IL (1) | IL173320A (sl) |
MX (1) | MXPA06001000A (sl) |
NZ (1) | NZ545009A (sl) |
PL (1) | PL1656410T3 (sl) |
PT (1) | PT1656410E (sl) |
SI (1) | SI1656410T1 (sl) |
WO (1) | WO2005010075A2 (sl) |
ZA (1) | ZA200600823B (sl) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8129330B2 (en) | 2002-09-30 | 2012-03-06 | Mountain View Pharmaceuticals, Inc. | Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof |
GB0314472D0 (en) | 2003-06-20 | 2003-07-23 | Warwick Effect Polymers Ltd | Polymer |
PT1656410E (pt) * | 2003-07-22 | 2010-06-11 | Nektar Therapeutics | Processo para preparação de polímeros funcionalizados a partir de álcoois poliméricos |
US20060045866A1 (en) * | 2004-09-01 | 2006-03-02 | Chris Chappelow | Novel high purity and high molecular weight mPEG alcohol compositions |
US7199193B2 (en) | 2004-09-28 | 2007-04-03 | Dow Global Technologies, Inc. | Polyethylene glycol compounds and process of making |
JP4920593B2 (ja) * | 2004-10-25 | 2012-04-18 | インテザイン テクノロジーズ, インコーポレイテッド | ヘテロ二官能性ポリ(エチレングリコール)およびそれらの使用 |
US7824919B2 (en) * | 2005-03-04 | 2010-11-02 | Dr. Reddy's Laboratories Limited | Method for analyzing activated polyethylene glycol compounds |
EP1926768B1 (en) | 2005-07-18 | 2011-09-14 | Nektar Therapeutics | Branched functionalized polymers using branched polyol cores |
KR100664969B1 (ko) * | 2005-08-26 | 2007-01-04 | 아이디비켐(주) | 고순도의 메톡시폴리에틸렌글리콜 및 그들의 유도체의제조방법 |
CN101420984B (zh) | 2006-02-21 | 2013-01-02 | 尼克塔治疗公司 | 嵌段可降解聚合物及由其制备的轭合物 |
US7560588B2 (en) | 2006-04-27 | 2009-07-14 | Intezyne Technologies, Inc. | Poly(ethylene glycol) containing chemically disparate endgroups |
PT2054074E (pt) | 2006-08-04 | 2014-11-07 | Prolong Pharmaceuticals Llc | Eritropoietina modificada |
US8501159B2 (en) * | 2006-12-18 | 2013-08-06 | Colorobbia Italia S.P.A. | Magnetic nanoparticles for the application in hyperthermia, preparation thereof and use in constructs having a pharmacological application |
EP2113009B1 (en) * | 2007-02-22 | 2018-11-21 | Biovectra Inc. | Process for purification of water soluble polymers |
JP2010528172A (ja) * | 2007-05-29 | 2010-08-19 | ヨウル チョン ケミカル カンパニー, リミテッド | 鎖末端官能性化したメトキシポリエチレングリコール及びこれを用いた金属ナノ粒子 |
US8440787B2 (en) * | 2007-10-23 | 2013-05-14 | Nektar Therapeutics | Hydroxyapatite-targeting multiarm polymers and conjugates made therefrom |
EP2240533A1 (en) * | 2008-02-01 | 2010-10-20 | Dow Global Technologies Inc. | Low diol content monofunctional alkoxypolyalkylene glycols and process for producing them |
CN104211943B (zh) * | 2014-09-17 | 2016-08-24 | 南京卡邦科技有限公司 | 一种制备分离单分散聚乙二醇的方法 |
EP3823904A4 (en) * | 2018-07-20 | 2022-04-20 | Hercules LLC | WATER-SOLUBLE OR DISPERSIBLE COMPOSITION |
US11045773B2 (en) * | 2018-08-31 | 2021-06-29 | Pall Corporation | Salt tolerant porous medium |
JP2022512627A (ja) | 2018-10-11 | 2022-02-07 | ネクター セラピューティクス | 遊離可能な高分子試薬を作製するための方法 |
KR20210149046A (ko) * | 2019-03-29 | 2021-12-08 | 니치유 가부시키가이샤 | 헤테로형 단분산 폴리에틸렌글리콜 유도체의 제조 방법 |
CN111718465B (zh) * | 2020-06-17 | 2021-07-20 | 华南理工大学 | 一种聚二硫缩醛及其制备方法和应用 |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0206448B1 (en) * | 1985-06-19 | 1990-11-14 | Ajinomoto Co., Inc. | Hemoglobin combined with a poly(alkylene oxide) |
US5080891A (en) * | 1987-08-03 | 1992-01-14 | Ddi Pharmaceuticals, Inc. | Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols |
FR2665449B1 (fr) * | 1990-08-02 | 1995-04-14 | Aquitaine Developp Transf Sang | Procede de fabrication de facteur von willebrand ayant une tres haute purete, depourvu en majeure partie de facteur antihemophilique (fviiic), et facteur von willebrand ainsi obtenu, ainsi qu'une composition pharmaceutique le contenant. |
US6261800B1 (en) * | 1989-05-05 | 2001-07-17 | Genentech, Inc. | Luteinizing hormone/choriogonadotropin (LH/CG) receptor |
US5252714A (en) * | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
US5281698A (en) * | 1991-07-23 | 1994-01-25 | Cetus Oncology Corporation | Preparation of an activated polymer ester for protein conjugation |
US5298410A (en) | 1993-02-25 | 1994-03-29 | Sterling Winthrop Inc. | Lyophilized formulation of polyethylene oxide modified proteins with increased shelf-life |
US5446090A (en) * | 1993-11-12 | 1995-08-29 | Shearwater Polymers, Inc. | Isolatable, water soluble, and hydrolytically stable active sulfones of poly(ethylene glycol) and related polymers for modification of surfaces and molecules |
US5629384A (en) * | 1994-05-17 | 1997-05-13 | Consiglio Nazionale Delle Ricerche | Polymers of N-acryloylmorpholine activated at one end and conjugates with bioactive materials and surfaces |
US5650234A (en) * | 1994-09-09 | 1997-07-22 | Surface Engineering Technologies, Division Of Innerdyne, Inc. | Electrophilic polyethylene oxides for the modification of polysaccharides, polypeptides (proteins) and surfaces |
US5824784A (en) * | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
JP3562000B2 (ja) | 1994-12-14 | 2004-09-08 | 日本油脂株式会社 | ポリオキシアルキレンモノアミンの製造方法 |
US5932462A (en) * | 1995-01-10 | 1999-08-03 | Shearwater Polymers, Inc. | Multiarmed, monofunctional, polymer for coupling to molecules and surfaces |
US5795966A (en) * | 1995-02-22 | 1998-08-18 | Immunex Corp | Antagonists of interleukin-15 |
US5672662A (en) * | 1995-07-07 | 1997-09-30 | Shearwater Polymers, Inc. | Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications |
US6448369B1 (en) * | 1997-11-06 | 2002-09-10 | Shearwater Corporation | Heterobifunctional poly(ethylene glycol) derivatives and methods for their preparation |
ATE268609T1 (de) * | 1998-03-12 | 2004-06-15 | Nektar Therapeutics Al Corp | Polyethylenglycolderivate mit benachbarten reaktiven gruppen |
DK0985697T3 (da) * | 1998-03-24 | 2006-05-15 | Nof Corp | Oxiranderivater og fremgangsmåde til fremstilling deraf |
AU1325400A (en) * | 1998-10-26 | 2000-05-15 | University Of Utah Research Foundation | Method for preparation of polyethylene glycol aldehyde derivatives |
WO2001045796A2 (en) * | 1999-12-22 | 2001-06-28 | Shearwater Corporation | Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol) |
US6602498B2 (en) * | 2000-02-22 | 2003-08-05 | Shearwater Corporation | N-maleimidyl polymer derivatives |
EP1423093A4 (en) * | 2001-04-23 | 2005-11-30 | Wisconsin Alumni Res Found | BIFUNCTIONAL MODIFIED HYDROGEL |
US6835802B2 (en) * | 2001-06-04 | 2004-12-28 | Nobex Corporation | Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties |
JP4123856B2 (ja) * | 2001-07-31 | 2008-07-23 | 日油株式会社 | 生体関連物質の修飾剤およびポリオキシアルキレン誘導体の製造方法 |
GB0129121D0 (en) | 2001-12-05 | 2002-01-23 | Ic Vec Ltd | Compound |
ATE412684T1 (de) * | 2002-09-09 | 2008-11-15 | Nektar Therapeutics Al Corp | Verfahren zur herstellung von wasserlöslichen polymerderivaten mit terminalen carboxylgruppen |
DE60329627D1 (de) * | 2002-12-31 | 2009-11-19 | Nektar Therapeutics Al Corp | Hydrolysestabile maleimidendgruppen-enthaltende polymere |
DE60321825D1 (de) | 2002-12-31 | 2008-08-07 | Nektar Therapeutics Al Corp | Maleinsäureamid polymerderivate und ihre biokonjugate |
PT1656410E (pt) | 2003-07-22 | 2010-06-11 | Nektar Therapeutics | Processo para preparação de polímeros funcionalizados a partir de álcoois poliméricos |
WO2011112969A1 (en) * | 2010-03-11 | 2011-09-15 | Intezyne Technologies, Inc. | Poly(ethylene glycol) derivatives for metal-free click chemistry |
-
2004
- 2004-07-22 PT PT04778925T patent/PT1656410E/pt unknown
- 2004-07-22 US US10/897,386 patent/US8604159B2/en active Active
- 2004-07-22 NZ NZ545009A patent/NZ545009A/en unknown
- 2004-07-22 EP EP04778925A patent/EP1656410B1/en active Active
- 2004-07-22 ES ES04778925T patent/ES2341960T3/es active Active
- 2004-07-22 CA CA2533702A patent/CA2533702C/en active Active
- 2004-07-22 AT AT04778925T patent/ATE460451T1/de active
- 2004-07-22 KR KR1020067001955A patent/KR101131411B1/ko active IP Right Grant
- 2004-07-22 SI SI200431425T patent/SI1656410T1/sl unknown
- 2004-07-22 DE DE602004025949T patent/DE602004025949D1/de active Active
- 2004-07-22 WO PCT/US2004/023633 patent/WO2005010075A2/en active Application Filing
- 2004-07-22 PL PL04778925T patent/PL1656410T3/pl unknown
- 2004-07-22 DK DK04778925.0T patent/DK1656410T3/da active
- 2004-07-22 AU AU2004259327A patent/AU2004259327B2/en active Active
- 2004-07-22 MX MXPA06001000A patent/MXPA06001000A/es active IP Right Grant
-
2006
- 2006-01-24 IL IL173320A patent/IL173320A/en active IP Right Grant
- 2006-01-27 ZA ZA200600823A patent/ZA200600823B/en unknown
-
2010
- 2010-06-07 CY CY20101100505T patent/CY1110169T1/el unknown
-
2013
- 2013-11-07 US US14/074,421 patent/US20140073802A1/en not_active Abandoned
-
2016
- 2016-11-22 US US15/359,344 patent/US10144804B2/en active Active
-
2018
- 2018-10-19 US US16/165,903 patent/US10941248B2/en active Active
-
2021
- 2021-02-03 US US17/165,958 patent/US20210347941A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20170073468A1 (en) | 2017-03-16 |
US20210347941A1 (en) | 2021-11-11 |
US20190055354A1 (en) | 2019-02-21 |
DK1656410T3 (da) | 2010-06-28 |
US20140073802A1 (en) | 2014-03-13 |
EP1656410B1 (en) | 2010-03-10 |
KR101131411B1 (ko) | 2012-07-05 |
KR20060069431A (ko) | 2006-06-21 |
AU2004259327A1 (en) | 2005-02-03 |
US8604159B2 (en) | 2013-12-10 |
CA2533702A1 (en) | 2005-02-03 |
PT1656410E (pt) | 2010-06-11 |
DE602004025949D1 (de) | 2010-04-22 |
CY1110169T1 (el) | 2015-01-14 |
MXPA06001000A (es) | 2006-05-15 |
ATE460451T1 (de) | 2010-03-15 |
AU2004259327B2 (en) | 2009-12-17 |
NZ545009A (en) | 2009-11-27 |
US10144804B2 (en) | 2018-12-04 |
US10941248B2 (en) | 2021-03-09 |
ZA200600823B (en) | 2007-04-25 |
PL1656410T3 (pl) | 2010-08-31 |
IL173320A (en) | 2011-02-28 |
WO2005010075A2 (en) | 2005-02-03 |
CA2533702C (en) | 2012-05-22 |
ES2341960T3 (es) | 2010-06-30 |
EP1656410A2 (en) | 2006-05-17 |
WO2005010075A3 (en) | 2005-04-07 |
US20050054816A1 (en) | 2005-03-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PL1656410T3 (pl) | Sposób wytwarzania sfunkcjonalizowanych polimerów z polimerycznych alkoholi | |
MXPA05012776A (es) | Sistemas de reticulacion para polimeros de hidroxilo. | |
WO2005072371A3 (en) | Branched polymeric sugars and nucleotides thereof | |
MXPA05003394A (es) | Conjugados de polimero con antigenicidad disminuida, metodos de preparacion y usos de estos. | |
WO2006047419A3 (en) | Heterobifunctional poly(ethylene glycol) and uses thereof | |
WO2007127473A3 (en) | Poly (ethylene glycol) containing chemically disparate endgroups | |
WO2007127440A3 (en) | Heterofunctional poly(ethylene glycol) containing acid-labile amino protecting groups and uses thereof | |
WO2008057697A3 (en) | Cross-linked polymer particles | |
MX2008000867A (es) | Metodo para preparar polimeros de maleimidas. | |
ATE494012T1 (de) | Stabilisierte polymer-thiol-reagenzien | |
EP1928930A4 (en) | POLYALKYLENE GLYCOL MONOMER, POLYALKYLENE GLYCOL POLYMER CONTAINING THE SAME AND APPLICATION THEREOF | |
WO2002010231A3 (en) | Polymeric compositions for forming optical waveguides; optical waveguides formed therefrom; and methods for making same | |
WO2007019331A3 (en) | Conjugates of a g-csf moiety and a polymer | |
TW200712121A (en) | Polymeric composition comprising polyolefins and amphiphilic block copolymers and optionally other polymers and/or fillers and dyeing or printing such compositions | |
WO2006128795A3 (de) | Verwendung von amphiphilen blockcopolymeren zur herstellung von polymerblends | |
TW200641025A (en) | Reverse phase hydrophilic polymers and their use in water-expandandable elastomeric compositions | |
ATE452662T1 (de) | Schmierstoffverbindung und daraus hergestelltes medizinisches instrument | |
MX2007004807A (es) | Composiciones para el cuidado del cabello. | |
WO2006081017A3 (en) | Toughened poly (ethylene terephthalate) compositions | |
DE50207876D1 (de) | Polymerzusammensetzung, enthaltend wenigstens ein mittelmolekulares reaktives polyisobuten | |
WO2005044904A3 (en) | Exfoliated polyolefin/clay nanocomposites using chain end functionalized polyolefin as the polymeric surfactant | |
ATE410473T1 (de) | Polymerstrukturen mit einem hydrophil/lipophil- system | |
TW200617071A (en) | Polytrimethylene ether ester elastomer flexible films | |
BR9909136A (pt) | Polìmero modificado e membranas poliméricas modificadas | |
WO2006102659A3 (en) | CONJUGATES OF AN hGH MOIETY AND A POLYMER |