SI1610878T1 - Postopek za proizvodnjo delcev - Google Patents
Postopek za proizvodnjo delcevInfo
- Publication number
- SI1610878T1 SI1610878T1 SI200432196T SI200432196T SI1610878T1 SI 1610878 T1 SI1610878 T1 SI 1610878T1 SI 200432196 T SI200432196 T SI 200432196T SI 200432196 T SI200432196 T SI 200432196T SI 1610878 T1 SI1610878 T1 SI 1610878T1
- Authority
- SI
- Slovenia
- Prior art keywords
- particles
- production
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/0018—Evaporation of components of the mixture to be separated
- B01D9/0027—Evaporation of components of the mixture to be separated by means of conveying fluid, e.g. spray-crystallisation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D9/00—Crystallisation
- B01D9/0081—Use of vibrations, e.g. ultrasound
-
- C—CHEMISTRY; METALLURGY
- C30—CRYSTAL GROWTH
- C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
- C30B29/00—Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape
- C30B29/54—Organic compounds
-
- C—CHEMISTRY; METALLURGY
- C30—CRYSTAL GROWTH
- C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
- C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Materials Engineering (AREA)
- Metallurgy (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0304037A GB0304037D0 (en) | 2003-02-21 | 2003-02-21 | Process for the production of particles for use in pharmaceutical formulations |
GB0313129A GB0313129D0 (en) | 2003-06-06 | 2003-06-06 | Process for the production of particles |
PCT/GB2004/000654 WO2004073827A1 (en) | 2003-02-21 | 2004-02-19 | Process for the production of particles |
EP04712610.7A EP1610878B1 (en) | 2003-02-21 | 2004-02-19 | Process for the production of particles |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1610878T1 true SI1610878T1 (sl) | 2015-02-27 |
Family
ID=32910470
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200432196T SI1610878T1 (sl) | 2003-02-21 | 2004-02-19 | Postopek za proizvodnjo delcev |
Country Status (11)
Country | Link |
---|---|
US (2) | US20070065372A1 (sl) |
EP (1) | EP1610878B1 (sl) |
JP (1) | JP5154078B2 (sl) |
CA (1) | CA2516733C (sl) |
DK (1) | DK1610878T3 (sl) |
ES (1) | ES2520841T3 (sl) |
NO (1) | NO20053796L (sl) |
PL (1) | PL224720B1 (sl) |
PT (1) | PT1610878E (sl) |
SI (1) | SI1610878T1 (sl) |
WO (1) | WO2004073827A1 (sl) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080259519A1 (en) * | 2004-09-14 | 2008-10-23 | Battelle Memorial Institute | Highly-Aqueous, Non-Respirable Aerosols Containing Biologically-Active Ingredients, Method of Making, and Device Therefor |
US8658089B2 (en) * | 2005-08-04 | 2014-02-25 | Saban Ventures Pty Limited | Membrane concentrator |
GB0525852D0 (en) * | 2005-12-20 | 2006-02-01 | Accentus Plc | Crystallisation apparatus and process |
FR2897281B1 (fr) * | 2006-02-14 | 2009-01-23 | Saint Louis Inst | Procede de fabrication par nanocristallisation de composes energetiques ou inertes |
JP4597107B2 (ja) * | 2006-03-02 | 2010-12-15 | 三井金属鉱業株式会社 | 砒素含有体からの砒素除去方法及び砒素除去装置 |
GB0610090D0 (en) * | 2006-05-20 | 2006-06-28 | Price Robert | Particulate drug compositions and their uses |
US20100034697A1 (en) | 2007-02-02 | 2010-02-11 | Saban Ventures Pty Limited | Membrane vapour concentrator |
GB0705159D0 (en) * | 2007-03-19 | 2007-04-25 | Prosonix Ltd | Process for making crystals |
ES2310131B1 (es) * | 2007-06-04 | 2009-12-04 | INSTITUTO NACIONAL DE TECNICA AEROESPACIAL "ESTEBAN TERRADAS" | Procedimiento de cristalizacion a partir de solucion. |
GB0711680D0 (en) * | 2007-06-18 | 2007-07-25 | Prosonix Ltd | Process |
GB0806873D0 (en) * | 2008-04-16 | 2008-05-21 | Breath Ltd | Steroid nebuliser formulation |
MX2011000405A (es) | 2008-07-18 | 2011-03-04 | Prosonix Ltd | Proceso para mejorar la cristalinidad. |
WO2010097188A1 (en) | 2009-02-25 | 2010-09-02 | Chiesi Farmaceutici S.P.A. | Inhalation particles comprising a salt of carmoterol and a corticosteroid |
GB0914240D0 (en) | 2009-08-14 | 2009-09-30 | Breath Ltd | Steroid solvates |
GB0914231D0 (en) | 2009-08-14 | 2009-09-30 | Breath Ltd | Dry powder inhaler formulations |
GB0918431D0 (en) | 2009-10-21 | 2009-12-09 | Prosonix Ltd | Process for improving crystallinity |
WO2011120779A1 (en) | 2010-04-01 | 2011-10-06 | Chiesi Farmaceutici S.P.A. | Process for preparing carrier particles for dry powders for inhalation |
EP2500072A1 (en) | 2011-03-15 | 2012-09-19 | LEK Pharmaceuticals d.d. | A novel process of residual solvent removal |
CN102166504B (zh) * | 2011-03-22 | 2013-03-06 | 中国人民解放军第三0九医院 | 一种凝胶微球快速成型装置及方法 |
CN102350280B (zh) * | 2011-06-23 | 2013-06-05 | 中国人民解放军第三0九医院 | 具有超声波振动装置的静电液滴发生装置及应用其制备载药凝胶微球的方法 |
US9643996B2 (en) | 2011-11-04 | 2017-05-09 | Battelle Memorial Institute | Processes for producing protein microparticles |
US8765725B2 (en) | 2012-05-08 | 2014-07-01 | Aciex Therapeutics, Inc. | Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof |
DK3517541T3 (da) | 2012-05-08 | 2020-09-07 | Nicox Ophthalmics Inc | Polymorf form af fluticasonpropionat |
US9815865B2 (en) | 2013-01-07 | 2017-11-14 | Nicox Ophthalmics, Inc. | Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof |
CN104721052A (zh) * | 2015-02-10 | 2015-06-24 | 武汉工程大学 | 一种纳米药物制备装置 |
GB2551944B (en) * | 2015-12-18 | 2021-09-01 | Midatech Pharma Wales Ltd | Microparticle production process and apparatus |
US10583085B2 (en) | 2017-05-17 | 2020-03-10 | Chiesi Farmaceutici S.P.A. | Carrier particles for dry powder formulations for inhalation |
KR102092068B1 (ko) * | 2018-03-26 | 2020-03-23 | 중앙대학교 산학협력단 | 약물 결정의 제조를 위한 비용매를 이용한 결정화 장치 및 이를 이용한 약물 결정의 제조 방법 |
US11813360B2 (en) | 2018-07-27 | 2023-11-14 | Chiesi Farmaceutici S.P.A. | Carrier particles for dry powder formulations for inhalation |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0432232B1 (en) * | 1989-05-01 | 1994-01-05 | Alkermes Controlled Therapeutics, Inc. | Process for producing small particles of biologically active molecules |
US5376386A (en) * | 1990-01-24 | 1994-12-27 | British Technology Group Limited | Aerosol carriers |
GB9105705D0 (en) * | 1991-03-18 | 1991-05-01 | Sandoz Ltd | Improvements in or relating to organic compounds |
US5993805A (en) * | 1991-04-10 | 1999-11-30 | Quadrant Healthcare (Uk) Limited | Spray-dried microparticles and their use as therapeutic vehicles |
GB9501841D0 (en) * | 1995-01-31 | 1995-03-22 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
SE9501384D0 (sv) * | 1995-04-13 | 1995-04-13 | Astra Ab | Process for the preparation of respirable particles |
US5874029A (en) * | 1996-10-09 | 1999-02-23 | The University Of Kansas | Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent |
DE19617085A1 (de) * | 1996-04-29 | 1997-10-30 | Bayer Ag | Verfahren zur Herstellung von feinstteiligen Kristallisationsprodukten |
JP3447042B2 (ja) * | 1997-07-23 | 2003-09-16 | フロイント産業株式会社 | 単一物質球形粒の製造方法 |
GB9828721D0 (en) * | 1998-12-24 | 1999-02-17 | Glaxo Group Ltd | Novel apparatus and process |
US6522582B1 (en) * | 1999-03-05 | 2003-02-18 | Xilinx, Inc. | Non-volatile memory array using gate breakdown structures |
JP3490015B2 (ja) * | 1999-03-11 | 2004-01-26 | 関西ティー・エル・オー株式会社 | 化学的耐久性に優れた放射性微小球及びその製造方法 |
FR2797875B1 (fr) * | 1999-08-26 | 2001-10-19 | Hoechst Marion Roussel Inc | Agglomerats spheriques de telithromycine, leur procede de preparation et leur application dans la preparation de formes pharmaceutiques |
GB9925934D0 (en) * | 1999-11-03 | 1999-12-29 | Glaxo Group Ltd | Novel apparatus and process |
CH694686A5 (it) * | 2000-03-04 | 2005-06-15 | Eco2 Sa | Prodotto di micronizzazione di sostanze farmaceutiche. |
GB0008411D0 (en) * | 2000-04-05 | 2000-05-24 | Vectura Ltd | Pharmaceutical preparations and their manufacture |
WO2001087277A2 (en) * | 2000-05-15 | 2001-11-22 | Vectura Limited | Method of manufacturing particles |
NZ529258A (en) * | 2001-05-05 | 2004-07-30 | Accentus Plc | Formation of small crystals |
EP1539319A4 (en) * | 2002-04-29 | 2005-10-12 | Bristol Myers Squibb Co | CRYSTALLIZATION SYSTEM USING ATOMIZATION |
GB0219815D0 (en) * | 2002-08-24 | 2002-10-02 | Accentus Plc | Preparation of small crystals |
-
2004
- 2004-02-19 EP EP04712610.7A patent/EP1610878B1/en not_active Revoked
- 2004-02-19 PT PT47126107T patent/PT1610878E/pt unknown
- 2004-02-19 WO PCT/GB2004/000654 patent/WO2004073827A1/en active Application Filing
- 2004-02-19 CA CA2516733A patent/CA2516733C/en not_active Expired - Fee Related
- 2004-02-19 SI SI200432196T patent/SI1610878T1/sl unknown
- 2004-02-19 PL PL378127A patent/PL224720B1/pl unknown
- 2004-02-19 JP JP2006502296A patent/JP5154078B2/ja not_active Expired - Fee Related
- 2004-02-19 ES ES04712610.7T patent/ES2520841T3/es not_active Expired - Lifetime
- 2004-02-19 US US10/546,433 patent/US20070065372A1/en not_active Abandoned
- 2004-02-19 DK DK04712610.7T patent/DK1610878T3/da active
-
2005
- 2005-08-11 NO NO20053796A patent/NO20053796L/no not_active Application Discontinuation
-
2016
- 2016-10-23 US US15/331,872 patent/US20170143632A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20170143632A1 (en) | 2017-05-25 |
NO20053796D0 (no) | 2005-08-11 |
US20070065372A1 (en) | 2007-03-22 |
DK1610878T3 (da) | 2014-12-01 |
PL224720B1 (pl) | 2017-01-31 |
NO20053796L (no) | 2005-11-03 |
EP1610878A1 (en) | 2006-01-04 |
CA2516733C (en) | 2011-09-27 |
WO2004073827A1 (en) | 2004-09-02 |
PT1610878E (pt) | 2014-12-03 |
ES2520841T3 (es) | 2014-11-11 |
JP5154078B2 (ja) | 2013-02-27 |
EP1610878B1 (en) | 2014-09-03 |
PL378127A1 (pl) | 2006-03-06 |
JP2006519780A (ja) | 2006-08-31 |
CA2516733A1 (en) | 2004-09-02 |
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