SI1608414T1 - Izboljšani osteoinduktivni matriali - Google Patents

Izboljšani osteoinduktivni matriali

Info

Publication number
SI1608414T1
SI1608414T1 SI200430818T SI200430818T SI1608414T1 SI 1608414 T1 SI1608414 T1 SI 1608414T1 SI 200430818 T SI200430818 T SI 200430818T SI 200430818 T SI200430818 T SI 200430818T SI 1608414 T1 SI1608414 T1 SI 1608414T1
Authority
SI
Slovenia
Prior art keywords
matrix material
morphogenetic protein
osteoinductive materials
protein
improved osteoinductive
Prior art date
Application number
SI200430818T
Other languages
English (en)
Inventor
Jens Pohl
Rolf Bechtold
Michael Kruse
Original Assignee
Bioph Biotech Entw Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioph Biotech Entw Pharm Gmbh filed Critical Bioph Biotech Entw Pharm Gmbh
Publication of SI1608414T1 publication Critical patent/SI1608414T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Dispersion Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pigments, Carbon Blacks, Or Wood Stains (AREA)
  • Prostheses (AREA)
SI200430818T 2003-03-28 2004-03-26 Izboljšani osteoinduktivni matriali SI1608414T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03007141A EP1462126A1 (en) 2003-03-28 2003-03-28 Improved Osteoinductive Materials
PCT/EP2004/003238 WO2004084965A2 (en) 2003-03-28 2004-03-26 Improved osteoinductive materials
EP04723595A EP1608414B1 (en) 2003-03-28 2004-03-26 Improved osteoinductive materials

Publications (1)

Publication Number Publication Date
SI1608414T1 true SI1608414T1 (sl) 2008-10-31

Family

ID=32798932

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200430818T SI1608414T1 (sl) 2003-03-28 2004-03-26 Izboljšani osteoinduktivni matriali

Country Status (14)

Country Link
US (2) US7485617B1 (sl)
EP (2) EP1462126A1 (sl)
JP (1) JP4863868B2 (sl)
AT (1) ATE400308T1 (sl)
AU (1) AU2004224768B2 (sl)
CA (1) CA2519174C (sl)
CY (1) CY1108386T1 (sl)
DE (1) DE602004014913D1 (sl)
DK (1) DK1608414T3 (sl)
ES (1) ES2305757T3 (sl)
PL (1) PL1608414T3 (sl)
PT (1) PT1608414E (sl)
SI (1) SI1608414T1 (sl)
WO (1) WO2004084965A2 (sl)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040081704A1 (en) 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
WO2003066000A2 (en) * 2002-02-08 2003-08-14 Wyeth Formulation comprising bioactive agents and method of using same
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
EP1462126A1 (en) * 2003-03-28 2004-09-29 BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH Improved Osteoinductive Materials
EP1880731A1 (en) * 2006-07-18 2008-01-23 BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH Human growth and differentiation factor GDF-5
AU2007234612B2 (en) 2006-12-14 2013-06-27 Johnson & Johnson Regenerative Therapeutics, Llc Protein stabilization formulations
DE102006060958A1 (de) 2006-12-20 2008-06-26 Jennissen, Herbert P., Prof. Dr. Verfahren zur Herstellung einer Polymermatrix, daraus bestehende Implantate sowie deren Verwendung
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
ES2402672T3 (es) * 2007-01-25 2013-05-07 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh Uso del GDF-5 para el mejoramiento o el mantenimiento del aspecto dérmico
US7678764B2 (en) 2007-06-29 2010-03-16 Johnson & Johnson Regenerative Therapeutics, Llc Protein formulations for use at elevated temperatures
US8058237B2 (en) 2007-08-07 2011-11-15 Advanced Technologies & Regenerative Medicine, LLC Stable composition of GDF-5 and method of storage
DE102007051914A1 (de) * 2007-10-29 2009-05-07 Herbert Prof. Dr. Jennissen Verfahren zur Herstellung von mit Wachstumsfaktoren beladenen Partikeln sowie die so erhaltenen Partikel
EP2276458A1 (en) * 2008-04-14 2011-01-26 Advanced Technologies and Regenerative Medicine, LLC Liquid buffered gdf-5 formulations
JPWO2010098421A1 (ja) * 2009-02-27 2012-09-06 株式会社オステオファーマ 改善された保存安定性を有する組換えヒト骨形成蛋白質
US8680182B2 (en) 2009-06-04 2014-03-25 Clemson University Research Foundation Methods for promoting the revascularization and reenervation of CNS lesions
US8609409B2 (en) 2009-06-04 2013-12-17 Clemson University Methods and compositions for cell culture platform
EP2598177B1 (en) 2010-07-30 2015-06-17 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka mbH Drug delivery devices and growth factor formulations for accelerated wound healing
AU2011329054B2 (en) 2010-11-15 2015-05-28 Zimmer Orthobiologics, Inc. Bone void fillers
US8551525B2 (en) 2010-12-23 2013-10-08 Biostructures, Llc Bone graft materials and methods
EP2537538A1 (en) 2011-06-22 2012-12-26 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka mbH Bioresorbable Wound Dressing
EP3229855B1 (en) 2014-12-09 2024-05-08 The Regents of the University of California Novel wound-healing-enhancing devices
US11324806B2 (en) * 2018-10-19 2022-05-10 Warsaw Orthopedic, Inc. Sustained delivery of a growth differentiation factor
CN111803718B (zh) * 2020-07-02 2022-02-25 西安交通大学医学院第二附属医院 一种抗纤维化药物缓释涂层及其制备方法
CN114432502B (zh) * 2021-12-31 2023-02-03 中山大学附属第八医院（深圳福田） 一种负载op3-4多肽、抗cxcl9抗体的水凝胶及其制备方法与应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4121043A1 (de) * 1991-06-26 1993-01-07 Merck Patent Gmbh Knochenersatzmaterial mit fgf
CA2093836A1 (en) * 1992-04-24 1993-10-25 Wayne Gombotz Biodegradable tgf-.beta. delivery system for bone regeneration
DE69403439T2 (de) * 1993-01-12 1997-10-23 Genentech Inc Tgf-beta zusammensetzung zum herbeiführen von knochenwachstum
JPH0788174A (ja) * 1993-09-28 1995-04-04 Yamanouchi Pharmaceut Co Ltd 骨形成用移植体
EP1074620A1 (en) * 1999-08-06 2001-02-07 HyGene AG Monomeric protein of the TGF-beta family
JPH10243996A (ja) * 1997-03-07 1998-09-14 Kagaku Gijutsu Shinko Jigyodan 硬組織石灰化促進用生体材料
AU3699900A (en) * 1999-02-16 2000-09-04 Sulzer Biologics, Inc. Device and method for regeneration and repair of cartilage lesions
JP5068918B2 (ja) * 2000-12-06 2012-11-07 ストラウマン ホールディング アーゲー 生体適合性が向上した医療用プロテーゼ装置およびインプラント
DK1448246T4 (en) * 2001-11-19 2015-12-21 Scil Technology Gmbh Homogeneously coated device with osteoinductive and osteoconductive properties
EP1462126A1 (en) * 2003-03-28 2004-09-29 BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH Improved Osteoinductive Materials

Also Published As

Publication number Publication date
WO2004084965A3 (en) 2004-11-25
AU2004224768B2 (en) 2008-05-22
AU2004224768A1 (en) 2004-10-07
ATE400308T1 (de) 2008-07-15
PT1608414E (pt) 2008-10-21
EP1462126A1 (en) 2004-09-29
DE602004014913D1 (de) 2008-08-21
EP1608414B1 (en) 2008-07-09
ES2305757T3 (es) 2008-11-01
EP1608414A2 (en) 2005-12-28
JP2006521135A (ja) 2006-09-21
US7485617B1 (en) 2009-02-03
CY1108386T1 (el) 2014-02-12
US8163694B2 (en) 2012-04-24
US20090155366A1 (en) 2009-06-18
WO2004084965A2 (en) 2004-10-07
JP4863868B2 (ja) 2012-01-25
CA2519174C (en) 2012-05-15
CA2519174A1 (en) 2004-10-07
PL1608414T3 (pl) 2009-02-27
DK1608414T3 (da) 2008-11-10

Similar Documents

Publication Publication Date Title
PT1608414E (pt) Materiais osteoindutores melhorados
EA199900725A1 (ru) Синергетические комбинации сульфонилмочевины и глитазона при лечении диабета
DE60134251D1 (de) Verwendung von glp-2-peptiden
DE602004031114D1 (de) Stickstoffhaltige heteroarylverbindungen und deren verwendungen zur erhoehung des gehaltes von endogenem erythropoietin
SV2003001144A (es) FORMAS CRISTALINAS DE LA SAL DE CALCIO DEL ACIDO [R-(R*,R*)]-2-(4-FLUOROFENIL)-ß,ô-DIHIDROXI-5-(1-METILETIL)-3-FENIL-4[(FENILAMINO)CARBONIL]-1H-PIRROL-1-HEPTANOICO (2:1) REF. PC430-01FJT
ATE342922T1 (de) Immobilisierung von proteinen mit hilfe eines polypeptidsegments
DK0967176T3 (da) Agglomerater på basis af aktivt kul, deres fremstillingsmåde og anvendelse som adsorptionsmidler
ATE296119T1 (de) Verdampfer zur verdampfung von flüchtigen verbindungen mit variabler verdampfungsintensität durch zwischengeschaltete mobile muffe
DE69831673D1 (de) Verwendung von exedinen und deren antagonisten zur verminderung der lebensmittelaufnahme
ES2138422T3 (es) Sistema de varios componentes para modificacion, degradacion o blanqueo de lignina, materiales que contienen lignina o materiales analogos, y proceso para su aplicacion.
GB9905020D0 (en) Therapeutic and diagnostic agents capable of modulating cellular responsiveness to cytokines
DE50003724D1 (de) VERWENDUNG VON 3-(2,4,6-TRIMETHYLPHENYL)- 4-NEOPENTYLCARBONYLOXY- 5,5-TETRAMETHYLEN- DOLLAR g(D)?3 - DIHYDROFURAN-2- N ZUR BEKÄMPFUNG DER WEISSEN FLIEGE
TW355750B (en) Optical component structure and its manufacturing
DE50015781D1 (de) Deren verwendung zum transport von molekülen über biologische membranen
KR960704045A (ko) E. coli csrA 유전자, 그것에 의해 암호화되는 단백질 및 그것의 사용법(THE ESCHERICHIA COLI carA GENE, PROTEIN ENCODED THEREBY, AND MITHODS OF USE THEREOF)
DE69514354D1 (de) Verfahren zur herstellung von verbesserten biologischen pestiziden
DE50208824D1 (de) Zusammensetzung zum zellspezifischen Transfer von Wirkstoffen
EP2292666A3 (en) Neoplasm specific antibodies and uses thereof
EA199800089A1 (ru) Газопроницаемый материал
EP0987549A3 (de) Testsystem zur Charakterisierung der Verträglichkeit von biologisch aktiven Substanzen und Polyvinylpyrrolidon
ES2133231B1 (es) Procedimiento y dispositivos para la emision constante de liquidos volatiles.
ATE172875T1 (de) Wirkstoffträger zur kontrollierten freisetzung von wirkstoffen im gastrointestinaltrakt mit verzögerter pyloruspassage
ATE528392T1 (de) Neues protein und dessen dns
ES2169890T3 (es) 3-mercapto-2-alquilalcan-1-oles y su utilizacion como sustancia olorosa o aromatica.
DE60326161D1 (de) Modifizierte hydrogele und ihre verwendung