SI1532974T1 - Zmes, ki vsebuje 6-(3-(1-adamantil)-4-metoksifenil)-2-naftensko kislino, za zdravljenje dermatoloških motenj - Google Patents
Zmes, ki vsebuje 6-(3-(1-adamantil)-4-metoksifenil)-2-naftensko kislino, za zdravljenje dermatoloških motenjInfo
- Publication number
- SI1532974T1 SI1532974T1 SI200331464T SI200331464T SI1532974T1 SI 1532974 T1 SI1532974 T1 SI 1532974T1 SI 200331464 T SI200331464 T SI 200331464T SI 200331464 T SI200331464 T SI 200331464T SI 1532974 T1 SI1532974 T1 SI 1532974T1
- Authority
- SI
- Slovenia
- Prior art keywords
- adamantyl
- treatment
- methoxyphenyl
- composition
- naphthoic acid
- Prior art date
Links
- 239000002253 acid Substances 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A—HUMAN NECESSITIES
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
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- A61P17/18—Antioxidants, e.g. antiradicals
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6903—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0203070A FR2837101B1 (fr) | 2002-03-12 | 2002-03-12 | Utilisation de l'acide 6-[1-adamantyl)-4-methoxyphenyl]-2- naphthoique pour le traitement de desordres dermatologiques |
US37022302P | 2002-04-08 | 2002-04-08 | |
EP05003144A EP1532974B1 (en) | 2002-03-12 | 2003-03-12 | Composition comprising 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid for the treatment of dermatological disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1532974T1 true SI1532974T1 (sl) | 2009-04-30 |
Family
ID=27806678
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200331650T SI1485080T1 (sl) | 2002-03-12 | 2003-03-12 | Uporaba adapalena za zdravljenje dermatoloških motenj |
SI200331464T SI1532974T1 (sl) | 2002-03-12 | 2003-03-12 | Zmes, ki vsebuje 6-(3-(1-adamantil)-4-metoksifenil)-2-naftensko kislino, za zdravljenje dermatoloških motenj |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200331650T SI1485080T1 (sl) | 2002-03-12 | 2003-03-12 | Uporaba adapalena za zdravljenje dermatoloških motenj |
Country Status (19)
Country | Link |
---|---|
US (17) | US7579377B2 (sl) |
EP (2) | EP1532974B1 (sl) |
JP (2) | JP2005526063A (sl) |
CN (1) | CN1642538B (sl) |
AT (2) | ATE417610T1 (sl) |
AU (2) | AU2003216898B2 (sl) |
BR (1) | BRPI0307550B8 (sl) |
CA (1) | CA2478237C (sl) |
CY (2) | CY1108868T1 (sl) |
DE (2) | DE60327745D1 (sl) |
DK (2) | DK1532974T3 (sl) |
ES (2) | ES2319778T3 (sl) |
HK (1) | HK1073996A1 (sl) |
MX (1) | MXPA04008684A (sl) |
PL (1) | PL216763B1 (sl) |
PT (2) | PT1532974E (sl) |
RU (2) | RU2332208C2 (sl) |
SI (2) | SI1485080T1 (sl) |
WO (1) | WO2003075908A1 (sl) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7820186B2 (en) | 2001-12-21 | 2010-10-26 | Galderma Research & Development | Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt |
DE60327745D1 (de) | 2002-03-12 | 2009-07-09 | Galderma Res & Dev | Verwendung von adapalen zur behandlung dermatologischer erkrankungen |
US20060128808A1 (en) * | 2004-10-20 | 2006-06-15 | Galderma Research & Development, S.N.C. | Method of using adapalene in acne maintenance therapy |
US20080161273A1 (en) * | 2004-10-20 | 2008-07-03 | Galderma Research & Development | Method of Using Adapalene in Acne Maintenance Therapy |
KR20070091613A (ko) * | 2004-11-08 | 2007-09-11 | 그렌마크 파머수티칼스 엘티디. | 항여드름 화합물 및 항생제 화합물을 함유하는 국소적 제약조성물 |
FR2879459B1 (fr) * | 2004-12-22 | 2007-02-16 | Galderma Res & Dev | Composition comprenant de l'adapalene solubilise avec des cyclodextrines |
CA2591062A1 (en) * | 2005-01-26 | 2006-08-03 | Galderma Research & Development | Adapalene for the long-term treatment of acne vulgaris |
ITRM20050248A1 (it) * | 2005-05-20 | 2006-11-21 | Sigma Tau Ind Farmaceuti | Uso acido adamantil metossidifenil propenoico per il trattamento di patologie cutanee. |
SI1902010T1 (sl) | 2005-06-17 | 2012-07-31 | Medichem Sa | Postopek za pripravo adapalena in odvisnih spojin |
FR2890861B1 (fr) | 2005-09-16 | 2010-05-28 | Galderma Res & Dev | Compositions comprenant au moins un derive de l'acide naphtoique et au moins un compose de type polymeres de polyurethanes ou des derives de celui-ci, leurs procede de preparation, et leur utilisation |
EP1933827A2 (en) * | 2005-09-16 | 2008-06-25 | Galderma Research & Development, S.N.C. | Composition comprising at least one naphthoic acid derivative and at least one compound of polyurethane polymer type or derivatives thereof, preparation processes therefor and uses thereof |
FR2894821B1 (fr) * | 2005-12-15 | 2008-02-29 | Galderma Res & Dev | Compositions comprenant au moins un compose retinoide et au moins un compose anti-irritant et leurs utilisations |
CN1989956B (zh) * | 2005-12-29 | 2010-09-01 | 北京德众万全医药科技有限公司 | 一种阿达帕林凝胶组合物及其制备方法 |
FR2901701B1 (fr) * | 2006-05-31 | 2010-10-29 | Galderma Res & Dev | Compostions comprenant au moins un derive de l'acide naphtoique et au moins un agent filmogene, leurs procedes de preparation, et leurs utilisations |
WO2008062135A1 (fr) * | 2006-11-20 | 2008-05-29 | Galderma Research & Development | Utilisation d'adapalène pour moduler l'expression de l'il-1ra. |
FR2909000B1 (fr) * | 2006-11-28 | 2009-02-06 | Galderma Res & Dev S N C Snc | Compositions comprenant du peroxyde de benzoyle, au moins un derive de l'acide naphtoique et au moins un compose de type polymeres de polyurethane ou des derives de celui-ci, et leurs utilisations. |
DK2308957T3 (da) * | 2006-12-15 | 2013-05-13 | Colgate Palmolive Co | Flydende vaskemiddel-sammensætning |
FR2910321B1 (fr) | 2006-12-21 | 2009-07-10 | Galderma Res & Dev S N C Snc | Gel creme comprenant au moins un retinoide et du peroxyde de benzole |
FR2910320B1 (fr) | 2006-12-21 | 2009-02-13 | Galderma Res & Dev S N C Snc | Emulsion comprenant au moins un retinoide et du peroxyde de benzole |
JP5338030B2 (ja) * | 2007-01-31 | 2013-11-13 | 大正製薬株式会社 | アダパレン含有外用剤組成物 |
JP5125122B2 (ja) * | 2007-01-31 | 2013-01-23 | 大正製薬株式会社 | アダパレン含有外用剤組成物 |
JP5670008B2 (ja) * | 2007-01-31 | 2015-02-18 | 大正製薬株式会社 | アダパレン含有外用剤組成物 |
WO2008111296A1 (ja) | 2007-03-09 | 2008-09-18 | Kyoto University | 角化の亢進に起因する皮膚疾患の予防及び治療のための医薬 |
EP2065032A1 (en) * | 2007-11-27 | 2009-06-03 | Galderma Research & Development | A method for producing adapalene gels |
US20110117182A1 (en) * | 2009-07-30 | 2011-05-19 | Allergan, Inc. | Combination of dapsone with other anti-acne agents |
WO2011135090A1 (en) * | 2010-04-29 | 2011-11-03 | Galderma Research & Development | Method for treating scars with adapalene 0.3% |
US10758630B2 (en) | 2010-08-13 | 2020-09-01 | The Johns Hopkins University | Topical compositions and methods of detection and treatment |
DE102010063825A1 (de) * | 2010-12-22 | 2012-06-28 | Beiersdorf Ag | Kosmetische oder dermatologische wasserfeste Lichtschutzzubereitungen umfassend eine Kombination aus Polyacrylat- und Polyacrylamidverdicker |
FR2969492B1 (fr) * | 2010-12-23 | 2013-07-05 | Galderma Res & Dev | Mousses dermatologiques obtenues a partir d'un gel ou d'une suspension contenant de l'adapalene |
JP5876468B2 (ja) * | 2011-02-25 | 2016-03-02 | 久光製薬株式会社 | 経皮または経粘膜投与のためのアジュバントおよびこれを含む医薬製剤 |
US10787177B2 (en) | 2011-06-29 | 2020-09-29 | SMR Patents S.à.r.l. | Exterior rearview device with illumination functions and autonomous vehicles using same |
US10137823B2 (en) | 2011-06-29 | 2018-11-27 | SMR Patents S.à.r.l. | Exterior rearview device with illumination functions |
US9206381B2 (en) | 2011-09-21 | 2015-12-08 | Ecolab Usa Inc. | Reduced misting alkaline cleaners using elongational viscosity modifiers |
FR2991175B1 (fr) * | 2012-06-01 | 2014-12-19 | Galderma Res & Dev | Compositions pharmaceutiques topiques de type emulsion h/e contenant un retinoide |
RU2538680C2 (ru) * | 2013-03-12 | 2015-01-10 | Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") | Фармацевтическая композиция для лечения атопического дерматита и способ ее получения |
JP5980171B2 (ja) * | 2013-06-05 | 2016-08-31 | 大正製薬株式会社 | アダパレン含有外用剤組成物 |
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