SI1427409T1 - Postopki za zdravljenje ali preprečevanje vaskularnega vnetja z uporabo zaviralca(-ev) absorpcije sterola - Google Patents
Postopki za zdravljenje ali preprečevanje vaskularnega vnetja z uporabo zaviralca(-ev) absorpcije sterolaInfo
- Publication number
- SI1427409T1 SI1427409T1 SI200230758T SI200230758T SI1427409T1 SI 1427409 T1 SI1427409 T1 SI 1427409T1 SI 200230758 T SI200230758 T SI 200230758T SI 200230758 T SI200230758 T SI 200230758T SI 1427409 T1 SI1427409 T1 SI 1427409T1
- Authority
- SI
- Slovenia
- Prior art keywords
- absorption inhibitor
- treating
- methods
- vascular inflammation
- preventing vascular
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32393701P | 2001-09-21 | 2001-09-21 | |
| EP02770534A EP1427409B1 (en) | 2001-09-21 | 2002-09-19 | Methods for treating or preventing vascular inflammation using sterol absorption inhibitor(s) |
| PCT/US2002/029756 WO2003026644A1 (en) | 2001-09-21 | 2002-09-19 | Methods for treating or preventing vascular inflammation using sterol absorption inhibitor(s) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1427409T1 true SI1427409T1 (sl) | 2009-02-28 |
Family
ID=23261347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200230758T SI1427409T1 (sl) | 2001-09-21 | 2002-09-19 | Postopki za zdravljenje ali preprečevanje vaskularnega vnetja z uporabo zaviralca(-ev) absorpcije sterola |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20030119757A1 (enExample) |
| EP (1) | EP1427409B1 (enExample) |
| JP (2) | JP4395370B2 (enExample) |
| CN (2) | CN1556700A (enExample) |
| AT (1) | ATE411018T1 (enExample) |
| AU (2) | AU2002335770B2 (enExample) |
| BR (1) | BR0212907A (enExample) |
| CA (1) | CA2460344A1 (enExample) |
| CY (1) | CY1110894T1 (enExample) |
| DE (1) | DE60229406D1 (enExample) |
| DK (1) | DK1427409T3 (enExample) |
| ES (1) | ES2312624T3 (enExample) |
| HU (1) | HUP0401501A3 (enExample) |
| MX (1) | MXPA04002572A (enExample) |
| NO (1) | NO333968B1 (enExample) |
| NZ (1) | NZ531060A (enExample) |
| PT (1) | PT1427409E (enExample) |
| SI (1) | SI1427409T1 (enExample) |
| WO (1) | WO2003026644A1 (enExample) |
| ZA (1) | ZA200402104B (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002247019C1 (en) | 2001-01-26 | 2017-05-11 | Organon Llc | Combinations of peroxisome proliferator-activated receptor (PPAR) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications |
| DE60216300T2 (de) * | 2001-09-21 | 2007-06-28 | Schering Corp. | Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption |
| GB0215579D0 (en) * | 2002-07-05 | 2002-08-14 | Astrazeneca Ab | Chemical compounds |
| NZ539624A (en) * | 2002-09-27 | 2008-08-29 | Martek Biosciences Corp | Prophylactic docosahexaenoic acid therapy for patients with subclinical inflammation |
| CA2504878A1 (en) | 2002-11-06 | 2004-05-27 | Schering Corporation | Cholesterol absorption inhibitors for the treatment of demyelination |
| EP1601668B1 (en) | 2003-03-07 | 2008-08-27 | Schering Corporation | Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia |
| MXPA05009501A (es) | 2003-03-07 | 2005-10-18 | Schering Corp | Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
| MXPA05009502A (es) | 2003-03-07 | 2005-10-18 | Schering Corp | Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
| US7459442B2 (en) | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
| US20070003600A1 (en) * | 2003-06-11 | 2007-01-04 | Carolyn Moore | Methods for reducing c-reactive protein |
| WO2005046797A2 (en) * | 2003-11-05 | 2005-05-26 | Schering Corporation | Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions |
| NZ546940A (en) * | 2003-11-10 | 2008-11-28 | Microbia Inc | 4-Biarylyl-1-phenylazetidin-2-ones |
| GB0329778D0 (en) * | 2003-12-23 | 2004-01-28 | Astrazeneca Ab | Chemical compounds |
| JP4688819B2 (ja) | 2003-12-23 | 2011-05-25 | アストラゼネカ アクチボラグ | コレステロール吸収阻害活性を有するジフェニルアゼチジノン誘導体 |
| US7803838B2 (en) * | 2004-06-04 | 2010-09-28 | Forest Laboratories Holdings Limited | Compositions comprising nebivolol |
| US7838552B2 (en) | 2004-06-04 | 2010-11-23 | Forest Laboratories Holdings Limited | Compositions comprising nebivolol |
| CA2575014A1 (en) * | 2004-08-09 | 2006-02-16 | Takeda Pharmaceutical Company Limited | Crp lowering agent |
| UY29607A1 (es) * | 2005-06-20 | 2007-01-31 | Astrazeneca Ab | Compuestos quimicos |
| AR057380A1 (es) * | 2005-06-22 | 2007-11-28 | Astrazeneca Ab | Compuestos quimicos derivados de 2-azetidinona y uso terapeutico de los mismos |
| SA06270191B1 (ar) | 2005-06-22 | 2010-03-29 | استرازينيكا ايه بي | مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم |
| AR054482A1 (es) * | 2005-06-22 | 2007-06-27 | Astrazeneca Ab | Derivados de azetidinona para el tratamiento de hiperlipidemias |
| AR057383A1 (es) * | 2005-06-22 | 2007-12-05 | Astrazeneca Ab | Compuestos quimicos derivados de 2-azetidinona, formulacion farmaceutica y un proceso de preparacion del compuesto |
| MY148538A (en) * | 2005-06-22 | 2013-04-30 | Astrazeneca Ab | Novel 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions |
| RU2008136765A (ru) * | 2006-03-06 | 2010-04-20 | Тева Фармасьютикл Индастриес Лтд. (Il) | Композиции эзетимиба |
| AR060623A1 (es) * | 2006-04-27 | 2008-07-02 | Astrazeneca Ab | Compuestos derivados de 2-azetidinona y un metodo de preparacion |
| JP4740938B2 (ja) | 2007-12-27 | 2011-08-03 | ダイセル化学工業株式会社 | 6位高アセチル化セルロースジアセテート及びその製造方法 |
| EP2414529A2 (en) | 2009-04-01 | 2012-02-08 | Matrix Laboratories Ltd | Enzymatic process for the preparation of (s)-5-(4-fluoro-phenyl)-5-hydroxy- 1morpholin-4-yl-pentan-1-one, an intermediate of ezetimibe and further conversion to ezetimibe |
| CN103755616A (zh) * | 2013-12-31 | 2014-04-30 | 北京万全德众医药生物技术有限公司 | 一种制备依泽替米贝异构体的方法 |
| CN103755617A (zh) * | 2013-12-31 | 2014-04-30 | 北京万全德众医药生物技术有限公司 | 一种制备依折麦布关键杂质的方法 |
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| US5120729A (en) * | 1990-06-20 | 1992-06-09 | Merck & Co., Inc. | Beta-lactams as antihypercholesterolemics |
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-
2002
- 2002-09-19 DE DE60229406T patent/DE60229406D1/de not_active Expired - Lifetime
- 2002-09-19 BR BR0212907-8A patent/BR0212907A/pt not_active Application Discontinuation
- 2002-09-19 MX MXPA04002572A patent/MXPA04002572A/es active IP Right Grant
- 2002-09-19 HU HU0401501A patent/HUP0401501A3/hu unknown
- 2002-09-19 CA CA002460344A patent/CA2460344A1/en not_active Abandoned
- 2002-09-19 SI SI200230758T patent/SI1427409T1/sl unknown
- 2002-09-19 JP JP2003530281A patent/JP4395370B2/ja not_active Expired - Fee Related
- 2002-09-19 US US10/247,032 patent/US20030119757A1/en not_active Abandoned
- 2002-09-19 NZ NZ531060A patent/NZ531060A/en not_active IP Right Cessation
- 2002-09-19 AT AT02770534T patent/ATE411018T1/de active
- 2002-09-19 WO PCT/US2002/029756 patent/WO2003026644A1/en not_active Ceased
- 2002-09-19 DK DK02770534T patent/DK1427409T3/da active
- 2002-09-19 CN CNA028184343A patent/CN1556700A/zh active Pending
- 2002-09-19 PT PT02770534T patent/PT1427409E/pt unknown
- 2002-09-19 ES ES02770534T patent/ES2312624T3/es not_active Expired - Lifetime
- 2002-09-19 EP EP02770534A patent/EP1427409B1/en not_active Expired - Lifetime
- 2002-09-19 AU AU2002335770A patent/AU2002335770B2/en not_active Ceased
- 2002-09-19 CN CN200910261594A patent/CN101785772A/zh active Pending
-
2004
- 2004-03-16 ZA ZA2004/02104A patent/ZA200402104B/en unknown
- 2004-04-20 NO NO20041598A patent/NO333968B1/no not_active IP Right Cessation
-
2005
- 2005-11-18 AU AU2005234666A patent/AU2005234666B2/en not_active Ceased
-
2008
- 2008-12-08 CY CY20081101419T patent/CY1110894T1/el unknown
-
2009
- 2009-09-11 JP JP2009211106A patent/JP2009286801A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| ATE411018T1 (de) | 2008-10-15 |
| CA2460344A1 (en) | 2003-04-03 |
| HK1064950A1 (en) | 2005-02-08 |
| NZ531060A (en) | 2006-06-30 |
| AU2002335770B2 (en) | 2005-08-18 |
| AU2005234666A1 (en) | 2005-12-08 |
| US20030119757A1 (en) | 2003-06-26 |
| NO333968B1 (no) | 2013-11-04 |
| JP2009286801A (ja) | 2009-12-10 |
| DE60229406D1 (de) | 2008-11-27 |
| JP2005504092A (ja) | 2005-02-10 |
| DK1427409T3 (da) | 2009-01-12 |
| BR0212907A (pt) | 2004-10-13 |
| MXPA04002572A (es) | 2004-05-31 |
| EP1427409B1 (en) | 2008-10-15 |
| ZA200402104B (en) | 2005-06-29 |
| HUP0401501A3 (en) | 2012-02-28 |
| HUP0401501A2 (hu) | 2004-12-28 |
| WO2003026644A1 (en) | 2003-04-03 |
| PT1427409E (pt) | 2008-11-27 |
| CN1556700A (zh) | 2004-12-22 |
| CN101785772A (zh) | 2010-07-28 |
| ES2312624T3 (es) | 2009-03-01 |
| JP4395370B2 (ja) | 2010-01-06 |
| EP1427409A1 (en) | 2004-06-16 |
| NO20041598L (no) | 2004-06-17 |
| AU2005234666B2 (en) | 2006-09-21 |
| CY1110894T1 (el) | 2015-06-10 |
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