SI1343523T1 - Uporaba aktiviranega koagulacijskega faktorja VII za zdravljenje hudih krvavitev, induciranih s tromboliticno terapijo - Google Patents

Uporaba aktiviranega koagulacijskega faktorja VII za zdravljenje hudih krvavitev, induciranih s tromboliticno terapijo

Info

Publication number
SI1343523T1
SI1343523T1 SI200130694T SI200130694T SI1343523T1 SI 1343523 T1 SI1343523 T1 SI 1343523T1 SI 200130694 T SI200130694 T SI 200130694T SI 200130694 T SI200130694 T SI 200130694T SI 1343523 T1 SI1343523 T1 SI 1343523T1
Authority
SI
Slovenia
Prior art keywords
factor vii
coagulation factor
activated coagulation
thrombolytic therapy
bleedings
Prior art date
Application number
SI200130694T
Other languages
English (en)
Inventor
Cord Skamira
Jean Marie Stassen
Gerhard Heusel
Wolfgang Wienen
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of SI1343523T1 publication Critical patent/SI1343523T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4846Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SI200130694T 2000-12-21 2001-12-20 Uporaba aktiviranega koagulacijskega faktorja VII za zdravljenje hudih krvavitev, induciranih s tromboliticno terapijo SI1343523T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00128252A EP1216709A1 (en) 2000-12-21 2000-12-21 Use of activated coagulation factor VII for treating thrombolytic therapy-induced major bleedings
PCT/EP2001/015132 WO2002049665A2 (en) 2000-12-21 2001-12-20 Use of activated coagulation factor vii for treating thrombolytic therapy-induced major bleedings
EP01995705A EP1343523B1 (en) 2000-12-21 2001-12-20 Use of activated coagulation factor vii for treating thrombolytic therapy-induced major bleedings

Publications (1)

Publication Number Publication Date
SI1343523T1 true SI1343523T1 (sl) 2007-04-30

Family

ID=8170769

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200130694T SI1343523T1 (sl) 2000-12-21 2001-12-20 Uporaba aktiviranega koagulacijskega faktorja VII za zdravljenje hudih krvavitev, induciranih s tromboliticno terapijo

Country Status (25)

Country Link
US (2) US20040087502A1 (sl)
EP (2) EP1216709A1 (sl)
JP (1) JP2004516273A (sl)
KR (1) KR20030063454A (sl)
CN (1) CN1482919A (sl)
AT (1) ATE353666T1 (sl)
AU (2) AU2638602A (sl)
BR (1) BR0116151A (sl)
CA (1) CA2431986A1 (sl)
CY (1) CY1106363T1 (sl)
CZ (1) CZ300670B6 (sl)
DE (1) DE60126650T2 (sl)
DK (1) DK1343523T3 (sl)
EC (1) ECSP034647A (sl)
ES (1) ES2280429T3 (sl)
HU (1) HUP0302574A3 (sl)
IL (1) IL155886A0 (sl)
MX (1) MXPA03005641A (sl)
NZ (1) NZ549850A (sl)
PL (1) PL205878B1 (sl)
PT (1) PT1343523E (sl)
RU (1) RU2286796C2 (sl)
SI (1) SI1343523T1 (sl)
WO (1) WO2002049665A2 (sl)
ZA (1) ZA200304140B (sl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0512316A (pt) * 2004-06-21 2008-02-26 Novo Nordisk Healthcare Ag métodos para prevenir ou atenuar uma ou mais complicações da hemorragia intracerebral e para prevenir ou atenuar uma ou mais complicações da ich em uma maioria de pacientes com ich, e, uso de um primeiro agente de coagulação
WO2007009895A2 (en) * 2005-07-15 2007-01-25 Novo Nordisk Health Care Ag USE OF FACTOR VIIa OR FACTOR VIIa EQUIVALENTS FOR PREVENTING OR ATTENUATING HAEMORRHAGE GROWTH, AND/OR OEDEMA GENERATION FOLLOWING INTRACEREBRAL HAEMORRHAGE (ICH) IN PATIENTS TREATED WITH ANTIPLATELET THERAPY
JP2011509978A (ja) 2008-01-18 2011-03-31 ノボ ノルディスク ヘルス ケア アーゲー 選択されたICH患者亜集団における脳内出血(ICH)後の出血拡大、及び/又は浮腫生成の予防又は減弱のための、第VIIa因子又は第VIIa因子等価物の使用
RU2552339C1 (ru) * 2014-02-19 2015-06-10 Общество с ограниченной ответственностью фирма "Технология-Стандарт" Способ профилактики кровотечений, вызванных применением стрептокиназы, в эксперименте

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374617A (en) * 1992-05-13 1994-12-20 Oklahoma Medical Research Foundation Treatment of bleeding with modified tissue factor in combination with FVIIa
US5846517A (en) * 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
WO1998058661A1 (en) * 1997-06-23 1998-12-30 Novo Nordisk A/S Use of fviia for the treatment of bleedings in patients with a normal blood clotting cascade and normal platelet function

Also Published As

Publication number Publication date
RU2003122362A (ru) 2005-02-10
WO2002049665A2 (en) 2002-06-27
EP1216709A1 (en) 2002-06-26
RU2286796C2 (ru) 2006-11-10
MXPA03005641A (es) 2004-12-03
CZ20031743A3 (cs) 2003-11-12
CZ300670B6 (cs) 2009-07-15
EP1343523B1 (en) 2007-02-14
CA2431986A1 (en) 2002-06-27
PT1343523E (pt) 2007-03-30
IL155886A0 (en) 2003-12-23
US20040087502A1 (en) 2004-05-06
PL205878B1 (pl) 2010-06-30
ATE353666T1 (de) 2007-03-15
BR0116151A (pt) 2003-10-21
AU2638602A (en) 2002-07-01
DE60126650D1 (de) 2007-03-29
ES2280429T3 (es) 2007-09-16
KR20030063454A (ko) 2003-07-28
PL361855A1 (en) 2004-10-04
JP2004516273A (ja) 2004-06-03
NZ549850A (en) 2008-04-30
US20080286259A1 (en) 2008-11-20
EP1343523A2 (en) 2003-09-17
CN1482919A (zh) 2004-03-17
DK1343523T3 (da) 2007-04-10
ECSP034647A (es) 2003-07-25
ZA200304140B (en) 2004-04-22
HUP0302574A3 (en) 2010-01-28
HUP0302574A2 (hu) 2003-10-28
DE60126650T2 (de) 2007-10-31
CY1106363T1 (el) 2011-10-12
AU2002226386B2 (en) 2005-12-22
WO2002049665A3 (en) 2002-09-26

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