SI1135381T1 - Eletriptan hidrobromid monohidrat - Google Patents

Eletriptan hidrobromid monohidrat

Info

Publication number
SI1135381T1
SI1135381T1 SI9930633T SI9930633T SI1135381T1 SI 1135381 T1 SI1135381 T1 SI 1135381T1 SI 9930633 T SI9930633 T SI 9930633T SI 9930633 T SI9930633 T SI 9930633T SI 1135381 T1 SI1135381 T1 SI 1135381T1
Authority
SI
Slovenia
Prior art keywords
eletriptan hydrobromide
hydrobromide monohydrate
monohydrate
eletriptan
hydrobromide
Prior art date
Application number
SI9930633T
Other languages
English (en)
Inventor
Christopher Ian Dallman
Ronald James Ogilvie
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of SI1135381T1 publication Critical patent/SI1135381T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Electroluminescent Light Sources (AREA)
  • Lasers (AREA)
  • Indole Compounds (AREA)
SI9930633T 1998-11-27 1999-11-01 Eletriptan hidrobromid monohidrat SI1135381T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9825988.0A GB9825988D0 (en) 1998-11-27 1998-11-27 Indole derivatives
PCT/IB1999/001754 WO2000032589A1 (en) 1998-11-27 1999-11-01 Eletriptan hydrobromide monohydrate
EP99949292A EP1135381B1 (en) 1998-11-27 1999-11-01 Eletriptan hydrobromide monohydrate

Publications (1)

Publication Number Publication Date
SI1135381T1 true SI1135381T1 (sl) 2004-10-31

Family

ID=10843140

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9930633T SI1135381T1 (sl) 1998-11-27 1999-11-01 Eletriptan hidrobromid monohidrat

Country Status (53)

Country Link
US (2) US20020013358A1 (sl)
EP (1) EP1135381B1 (sl)
JP (1) JP3777094B2 (sl)
KR (1) KR100413739B1 (sl)
CN (1) CN1131860C (sl)
AP (1) AP2001002149A0 (sl)
AR (1) AR024232A1 (sl)
AT (1) ATE273300T1 (sl)
AU (1) AU754731B2 (sl)
BG (1) BG64706B1 (sl)
BR (1) BR9915692A (sl)
CA (1) CA2352392C (sl)
CO (1) CO5150178A1 (sl)
CR (1) CR6325A (sl)
CU (1) CU23269A3 (sl)
CZ (1) CZ295472B6 (sl)
DE (1) DE69919388T2 (sl)
DK (1) DK1135381T3 (sl)
DZ (1) DZ2948A1 (sl)
EA (1) EA003551B1 (sl)
EE (1) EE04914B1 (sl)
ES (1) ES2224701T3 (sl)
GB (1) GB9825988D0 (sl)
GC (1) GC0000113A (sl)
GE (1) GEP20043183B (sl)
GT (1) GT199900202A (sl)
HK (1) HK1042898B (sl)
HN (1) HN1999000196A (sl)
HR (1) HRP20010398B1 (sl)
HU (1) HUP0105308A3 (sl)
ID (1) ID28802A (sl)
IL (1) IL141663A (sl)
IS (1) IS2238B (sl)
MA (1) MA26708A1 (sl)
MY (1) MY124078A (sl)
NO (1) NO320798B1 (sl)
NZ (1) NZ510055A (sl)
OA (1) OA11671A (sl)
PA (1) PA8485701A1 (sl)
PE (1) PE20001299A1 (sl)
PL (1) PL194503B1 (sl)
PT (1) PT1135381E (sl)
RS (1) RS50002B (sl)
SI (1) SI1135381T1 (sl)
SK (1) SK285774B6 (sl)
SV (1) SV1999000204A (sl)
TN (1) TNSN99221A1 (sl)
TR (1) TR200101493T2 (sl)
TW (1) TWI246512B (sl)
UA (1) UA68402C2 (sl)
UY (2) UY25823A1 (sl)
WO (1) WO2000032589A1 (sl)
ZA (1) ZA200102681B (sl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0018968D0 (en) * 2000-08-02 2000-09-20 Pfizer Ltd Particulate composition
BRPI0409127A (pt) 2003-04-11 2006-03-28 Pfizer combinação farmacêutica compreendendo eletriptano e bicarbonato de sódio
US6927296B2 (en) 2003-07-23 2005-08-09 Pfizer Inc. Process
GB0317229D0 (en) * 2003-07-23 2003-08-27 Pfizer Ltd Improved process
EP2046777A2 (en) * 2007-05-01 2009-04-15 Plus Chemicals B.V. Amorphous eletriptan hydrobromide and process for preparing it and other forms of eletriptan hydrobromide
WO2008150500A1 (en) * 2007-05-29 2008-12-11 Plus Chemicals, S.A. A process for preparing 5-bromo-3-[(r)-1-methyl-pyrrolidin-2-ylmethyl]-1h-indole
EP2225224A2 (en) * 2007-12-17 2010-09-08 Actavis Group PTC EHF Novel hemioxalate salt of eletriptan
WO2010097703A1 (en) * 2009-02-25 2010-09-02 Actavis Group Ptc Ehf Highly pure eletriptan or a pharmaceutically acceptable salt thereof substantially free of eletriptan n-oxide impurity
WO2010116386A2 (en) * 2009-04-08 2010-10-14 Biophore India Pharmaceuticals Pvt. Ltd. Novel polymorph of eletriptan hydrobromide and process for the preparation thereof
WO2011089614A1 (en) * 2010-01-19 2011-07-28 Sms Pharmaceuticals Limited PROCESS FOR PREPARING ELETRIPTAN HYDROBROMIDE HAVING α-FORM
WO2014063752A1 (en) 2012-10-26 2014-05-01 Synthon Bv Process for making crystalline form alpha of eletriptan hydrobromide
CN103893112A (zh) * 2012-12-31 2014-07-02 重庆圣华曦药业股份有限公司 氢溴酸依来曲普坦注射液
CN107954947A (zh) * 2016-10-14 2018-04-24 北京莱瑞森医药科技有限公司 沃替西汀氢溴酸盐晶型c及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3952741A (en) 1975-01-09 1976-04-27 Bend Research Inc. Controlled release delivery system by an osmotic bursting mechanism
FR2624732B1 (fr) 1987-12-21 1991-02-15 Synthelabo Formulation pharmaceutique a liberation prolongee
US5474784A (en) 1990-03-02 1995-12-12 British Technology Group Limited Dispensing device
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
WO1992006973A1 (en) 1990-10-15 1992-04-30 Pfizer Inc. Indole derivatives
US5464633A (en) 1994-05-24 1995-11-07 Jagotec Ag Pharmaceutical tablets releasing the active substance after a definite period of time
GB9417310D0 (en) * 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
GB9510223D0 (en) 1995-05-20 1995-07-19 Pfizer Ltd Therapeutic agent
TW448172B (en) * 1996-03-08 2001-08-01 Pharmacia & Upjohn Co Llc Novel hydroxamic acid derivatives useful for the treatment of diseases related to connective tissue degradation
US5998462A (en) * 1996-12-16 1999-12-07 Allelix Biopharmaceuticals Inc. 5-alkyl indole compounds
GB9704498D0 (en) * 1997-03-05 1997-04-23 Glaxo Wellcome Spa Chemical compound
ID24528A (id) 1997-07-03 2000-07-20 Pfizer Komposisi-komposisi obat farmasi yang mengandung eletriptan hemisulfat dan kafein

Also Published As

Publication number Publication date
OA11671A (en) 2005-01-12
GB9825988D0 (en) 1999-01-20
EE200100285A (et) 2002-08-15
EE04914B1 (et) 2007-10-15
YU18801A (sh) 2003-07-07
EP1135381B1 (en) 2004-08-11
GC0000113A (en) 2005-06-29
GEP20043183B (en) 2004-02-25
NO320798B1 (no) 2006-01-30
UY25823A1 (es) 2001-08-27
UY25825A1 (es) 2000-08-21
PL194503B1 (pl) 2007-06-29
AP2001002149A0 (en) 2001-06-30
CR6325A (sl) 2008-07-02
NO20012584L (no) 2001-07-27
PA8485701A1 (es) 2000-09-29
AU6225399A (en) 2000-06-19
ES2224701T3 (es) 2005-03-01
HN1999000196A (es) 2005-11-26
SK285774B6 (sk) 2007-08-02
JP2002531449A (ja) 2002-09-24
KR100413739B1 (ko) 2004-01-03
CZ20011839A3 (cs) 2001-10-17
DE69919388D1 (de) 2004-09-16
HK1042898B (zh) 2004-10-08
IL141663A (en) 2004-05-12
SV1999000204A (es) 2000-10-16
CA2352392A1 (en) 2000-06-08
MY124078A (en) 2006-06-30
IL141663A0 (en) 2002-03-10
ZA200102681B (en) 2002-07-02
CO5150178A1 (es) 2002-04-29
CU23269A3 (es) 2008-04-09
SK6992001A3 (en) 2002-01-07
UA68402C2 (en) 2004-08-16
ATE273300T1 (de) 2004-08-15
BR9915692A (pt) 2001-08-14
MA26708A1 (fr) 2004-12-20
CZ295472B6 (cs) 2005-08-17
DZ2948A1 (fr) 2004-03-15
NZ510055A (en) 2004-11-26
US7238723B2 (en) 2007-07-03
HRP20010398A2 (en) 2002-06-30
TWI246512B (en) 2006-01-01
IS5868A (is) 2001-02-27
EP1135381A1 (en) 2001-09-26
AR024232A1 (es) 2002-09-25
ID28802A (id) 2001-07-05
JP3777094B2 (ja) 2006-05-24
TNSN99221A1 (fr) 2005-11-10
DE69919388T2 (de) 2005-09-29
US20050131237A1 (en) 2005-06-16
EA003551B1 (ru) 2003-06-26
BG105539A (en) 2001-12-29
HRP20010398B1 (en) 2004-12-31
CN1131860C (zh) 2003-12-24
DK1135381T3 (da) 2004-11-15
CN1328554A (zh) 2001-12-26
US20020013358A1 (en) 2002-01-31
CA2352392C (en) 2006-01-24
AU754731B2 (en) 2002-11-21
KR20010080594A (ko) 2001-08-22
EA200100297A1 (ru) 2001-08-27
GT199900202A (es) 2001-05-19
BG64706B1 (bg) 2005-12-30
PE20001299A1 (es) 2000-12-01
PT1135381E (pt) 2004-10-29
HUP0105308A3 (en) 2003-01-28
RS50002B (sr) 2008-09-29
NO20012584D0 (no) 2001-05-25
TR200101493T2 (tr) 2002-02-21
PL347928A1 (en) 2002-04-22
HK1042898A1 (en) 2002-08-30
HUP0105308A2 (hu) 2002-05-29
WO2000032589A1 (en) 2000-06-08
IS2238B (is) 2007-05-15

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