SI1125907T1 - Intermediates for the production of citalopram - Google Patents

Intermediates for the production of citalopram

Info

Publication number
SI1125907T1
SI1125907T1 SI200030487T SI200030487T SI1125907T1 SI 1125907 T1 SI1125907 T1 SI 1125907T1 SI 200030487 T SI200030487 T SI 200030487T SI 200030487 T SI200030487 T SI 200030487T SI 1125907 T1 SI1125907 T1 SI 1125907T1
Authority
SI
Slovenia
Prior art keywords
citalopram
compound
following formula
production
intermediates
Prior art date
Application number
SI200030487T
Other languages
English (en)
Slovenian (sl)
Inventor
Tetsuya Sumika Fine Chemicals Co. Ltd. Ikemoto
Wei-Guo c/o Sumika Fine Chemicals Co. Ltd. Gao
Nobuhiro Sumika Fine Chemicals Co. Ltd. Arai
Masami c/o Sumika Fine Chemicals Co. Ltd. Igi
Original Assignee
Sumitomo Chemical Company, Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26585589&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1125907(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sumitomo Chemical Company, Limited filed Critical Sumitomo Chemical Company, Limited
Publication of SI1125907T1 publication Critical patent/SI1125907T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C07C51/21—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen
    • C07C51/255—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen of compounds containing six-membered aromatic rings without ring-splitting
    • C07C51/265—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen of compounds containing six-membered aromatic rings without ring-splitting having alkyl side chains which are oxidised to carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/373—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in doubly bound form

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
SI200030487T 2000-02-17 2000-09-06 Intermediates for the production of citalopram SI1125907T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000039936 2000-02-17
JP2000065527 2000-03-09
EP00119222A EP1125907B1 (de) 2000-02-17 2000-09-06 Zwischenprodukte für die Herstellung von Citalopram

Publications (1)

Publication Number Publication Date
SI1125907T1 true SI1125907T1 (en) 2004-12-31

Family

ID=26585589

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030487T SI1125907T1 (en) 2000-02-17 2000-09-06 Intermediates for the production of citalopram

Country Status (10)

Country Link
US (5) US6433196B1 (de)
EP (2) EP1428813A1 (de)
AT (1) ATE271025T1 (de)
AU (1) AU777193B2 (de)
CA (1) CA2318701A1 (de)
DE (1) DE60012131T2 (de)
DK (1) DK1125907T3 (de)
ES (1) ES2220308T3 (de)
PT (1) PT1125907E (de)
SI (1) SI1125907T1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE237604T1 (de) * 1999-04-14 2003-05-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
AR026063A1 (es) * 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
IES20010143A2 (en) * 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
BR0109176A (pt) 2000-03-13 2003-04-22 Lundbeck & Co As H Método para preparação de citalopram e composto da fórmula
CA2402553A1 (en) * 2000-03-13 2001-09-20 H. Lundbeck A/S Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
IL151488A0 (en) 2000-03-14 2003-04-10 Lundbeck & Co As H Method for the preparation of citalopram
EP1274699A1 (de) 2000-03-16 2003-01-15 H. Lundbeck A/S Verfahren zur herstellung von 5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofuranen
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
EP1346989A1 (de) * 2002-03-21 2003-09-24 Jubilant Organosys Limited Verbessertes Verfahren zur Herstellung von Citalopram und Citalopram Hydrobromid
ITMI20030479A1 (it) * 2003-03-13 2004-09-14 Adorkem Technology S P A Procedimento per la preparazione di un ciano-isobenzofurano.
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
US20040202717A1 (en) 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
AU2003238676A1 (en) * 2003-04-21 2004-11-19 Podile Khadgapathi An improved process for the preparation of citalopram hydrobromide
WO2005047274A1 (en) * 2003-11-12 2005-05-26 Dr. Reddy's Laboratories, Inc. Preparation of escitalopram
DE602005025497D1 (de) 2004-08-05 2011-02-03 Sumitomo Chemical Co Verfahren zur herstellung von halogensubstituiertem benzoldimethanol
CN102190641A (zh) * 2011-03-23 2011-09-21 四川科伦药物研究有限公司 一种制备西酞普兰和艾司西酞普兰关键中间体的方法
CN104478690A (zh) * 2014-11-18 2015-04-01 四川大学 一种4,4’-二羧基二苯甲酮的制备方法

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US60640A (en) * 1866-12-18 peters
US40153A (en) * 1863-10-06 Improvement in bullets for fire-arms
US134895A (en) * 1873-01-14 Improvement in folding-cribs
US109577A (en) * 1870-11-29 Improvement in machines for
US83508A (en) * 1868-10-27 Improved car-brake
US114692A (en) * 1871-05-09 Improvement in chemical electric telegraphs
US4604A (en) * 1846-06-27 Apparatus for generating gas
GB1219609A (en) * 1968-07-19 1971-01-20 Koninklijke Pharma Fab Nv Diphenylmethoxyethylamino derivatives
US3642997A (en) 1969-06-25 1972-02-15 Merck & Co Inc Tricyclic carboxylic acids in the treatment of inflammation
US3835167A (en) 1972-12-18 1974-09-10 Syntex Inc Anthrone carboxylic acids and derivatives
US3959475A (en) * 1973-12-12 1976-05-25 American Hoechst Corporation Substituted 1,3-dihydrospiro(isobenzofuran)s
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
ES8700647A1 (es) 1984-10-11 1986-11-16 Raychem Corp Procedimiento para la preparacion de un compuesto carbonilo aromatico
US4940822A (en) * 1988-11-04 1990-07-10 Warner-Lambert Company Substituted benzenemethanol compounds, intermediates thereof, and preparation thereof
US5061810A (en) 1989-11-28 1991-10-29 Ethyl Corporation Substituted benzophenone dicarboxylic acids
EP0467435A3 (en) * 1990-07-19 1992-04-01 Akzo N.V. Benzhydryl derivatives having calmodulin inhibitor properties
US5198594A (en) * 1991-11-27 1993-03-30 Amoco Corporation Alkylation of alkylaromatics promoted by sonicated alkali metal
US5210313A (en) 1992-01-10 1993-05-11 Maxdem Incorporated Preparation of 2,5-dichlorobenzophenones
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
AU771252B2 (en) * 1998-07-13 2004-03-18 Nps Pharmaceuticals, Inc. Methods and compounds for treating depression and other disorders
ATE237604T1 (de) 1999-04-14 2003-05-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
US6310222B1 (en) * 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
NL1017415C1 (nl) * 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
EP1274699A1 (de) 2000-03-16 2003-01-15 H. Lundbeck A/S Verfahren zur herstellung von 5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofuranen
AR032455A1 (es) * 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
US20030109577A1 (en) 2000-10-27 2003-06-12 Ken Liljegren Pharmaceutical composition containing citalopram

Also Published As

Publication number Publication date
CA2318701A1 (en) 2001-08-17
US20040138497A1 (en) 2004-07-15
PT1125907E (pt) 2004-10-29
US6433196B1 (en) 2002-08-13
US7119215B2 (en) 2006-10-10
AU777193B2 (en) 2004-10-07
ATE271025T1 (de) 2004-07-15
US20020095051A1 (en) 2002-07-18
ES2220308T3 (es) 2004-12-16
EP1125907A2 (de) 2001-08-22
EP1428813A1 (de) 2004-06-16
US6458975B1 (en) 2002-10-01
DE60012131T2 (de) 2005-08-11
AU5656000A (en) 2001-08-23
US20020062040A1 (en) 2002-05-23
EP1125907A3 (de) 2002-05-02
EP1125907B1 (de) 2004-07-14
US6946564B2 (en) 2005-09-20
DK1125907T3 (da) 2004-10-18
US20040230066A1 (en) 2004-11-18
DE60012131D1 (de) 2004-08-19

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