SI0922703T1 - Substituted heterocyclic benzocycloalkenes and their use as analgesically active compounds - Google Patents
Substituted heterocyclic benzocycloalkenes and their use as analgesically active compoundsInfo
- Publication number
- SI0922703T1 SI0922703T1 SI9830350T SI9830350T SI0922703T1 SI 0922703 T1 SI0922703 T1 SI 0922703T1 SI 9830350 T SI9830350 T SI 9830350T SI 9830350 T SI9830350 T SI 9830350T SI 0922703 T1 SI0922703 T1 SI 0922703T1
- Authority
- SI
- Slovenia
- Prior art keywords
- active compounds
- substituted heterocyclic
- analgesically active
- benzocycloalkenes
- heterocyclic benzocycloalkenes
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/08—Naphthothiopyrans; Hydrogenated naphthothiopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19755480A DE19755480A1 (de) | 1997-12-13 | 1997-12-13 | Substituierte heterocyclische Benzocycloalkene und ihre Verwendung als analgetisch wirksame Substanzen |
| EP98122218A EP0922703B1 (de) | 1997-12-13 | 1998-11-23 | Substituierte heterocyclische Benzocycloalkene und ihre Verwendung als analgetisch wirksame Substanzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI0922703T1 true SI0922703T1 (en) | 2003-04-30 |
Family
ID=7851818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9830350T SI0922703T1 (en) | 1997-12-13 | 1998-11-23 | Substituted heterocyclic benzocycloalkenes and their use as analgesically active compounds |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6013809A (cs) |
| EP (1) | EP0922703B1 (cs) |
| JP (1) | JPH11246547A (cs) |
| KR (1) | KR19990062982A (cs) |
| CN (1) | CN100376564C (cs) |
| AR (1) | AR017800A1 (cs) |
| AT (1) | ATE229016T1 (cs) |
| AU (1) | AU747979B2 (cs) |
| BR (1) | BR9805437A (cs) |
| CA (1) | CA2256007C (cs) |
| CO (1) | CO4990950A1 (cs) |
| CZ (1) | CZ294990B6 (cs) |
| DE (2) | DE19755480A1 (cs) |
| DK (1) | DK0922703T3 (cs) |
| ES (1) | ES2189072T3 (cs) |
| HU (1) | HU226014B1 (cs) |
| IL (1) | IL127518A (cs) |
| MY (1) | MY133169A (cs) |
| NO (1) | NO985818L (cs) |
| NZ (1) | NZ332622A (cs) |
| PE (1) | PE133499A1 (cs) |
| PL (1) | PL194934B1 (cs) |
| PT (1) | PT922703E (cs) |
| RU (1) | RU2197484C2 (cs) |
| SI (1) | SI0922703T1 (cs) |
| SK (1) | SK283366B6 (cs) |
| UY (1) | UY25296A1 (cs) |
| ZA (1) | ZA9811346B (cs) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6077850A (en) * | 1997-04-21 | 2000-06-20 | G.D. Searle & Co. | Substituted benzopyran analogs for the treatment of inflammation |
| US6221897B1 (en) | 1998-06-10 | 2001-04-24 | Aventis Pharma Deutschland Gmbh | Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use |
| DE19830105C1 (de) * | 1998-07-06 | 2000-02-17 | Gruenenthal Gmbh | Acridinderivate |
| US6096780A (en) * | 1998-08-20 | 2000-08-01 | Takeda Chemical Industries, Ltd. | Quaternary ammonium salts and their use |
| DE10033459A1 (de) * | 2000-07-10 | 2002-01-24 | Gruenenthal Gmbh | Cyclische substituierte Aminomethylverbindungen und diese Verbindungen enthaltende Arzeimittel |
| US7289083B1 (en) * | 2000-11-30 | 2007-10-30 | Palm, Inc. | Multi-sided display for portable computer |
| BRPI0911622B8 (pt) * | 2008-04-28 | 2021-05-25 | Janssen Pharmaceutica Nv | derivados de benzoxepina e benzociclo-heptano, seu processo de preparação, seu uso e composição farmacêutica que os compreende |
| CN107375291A (zh) | 2011-10-28 | 2017-11-24 | 鲁美纳医药公司 | 用于治疗高胆血症和胆汁淤积性肝病的胆汁酸再循环抑制剂 |
| CN107375932B (zh) | 2011-10-28 | 2021-12-21 | 夏尔人类遗传性治疗公司 | 用于治疗小儿胆汁淤积性肝病的胆汁酸再循环抑制剂 |
| CN104844471B (zh) * | 2015-04-21 | 2017-05-03 | 苏州远智医药科技有限公司 | 一种作为dor受体拮抗剂的化合物 |
| CN109896991B (zh) * | 2017-12-08 | 2020-11-20 | 苏州远智医药科技有限公司 | 一种δ阿片受体拮抗剂及其用途和药物组合物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3444176A (en) * | 1967-04-28 | 1969-05-13 | Mcneilab Inc | Certain 4-diloweralkylamino-lower alkyl - 5 - pyridyl (or phenyl)-2,3-dihydro - 1 - benzothiepins and derivatives thereof |
| US4104280A (en) * | 1977-02-04 | 1978-08-01 | Syntex (U.S.A.) Inc. | Dibenzo [b.f]thiepin and dibenzo[b.f]oxepin derivatives |
| SU1321375A3 (ru) * | 1982-05-06 | 1987-06-30 | Фармиталиа Карло Эрба С.П.А. (Фирма) | Способ получени производных дигидробензопирана или дигидробензотиопирана или их фармацевтически приемлемых солей |
| JPS61130286A (ja) * | 1984-11-28 | 1986-06-18 | Suntory Ltd | ２，３−ジヒドロ−１−ベンズオキセピン誘導体 |
| CA1338894C (en) * | 1988-01-15 | 1997-02-04 | John Francis De Bernardis | Aminomethyl-chroman and thiochroman compounds as ó-2-adrenergic antagonists |
| DE4128690A1 (de) * | 1991-08-29 | 1993-03-04 | Boehringer Mannheim Gmbh | Bicyclische sulfone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| JP3042156B2 (ja) * | 1992-02-20 | 2000-05-15 | 田辺製薬株式会社 | ナフタレン誘導体、その製法及びその合成中間体 |
| ATE161530T1 (de) * | 1992-09-04 | 1998-01-15 | Takeda Chemical Industries Ltd | Kondensierte heterozyklische verbindungen, deren herstellung und verwendung |
-
1997
- 1997-12-13 DE DE19755480A patent/DE19755480A1/de not_active Ceased
-
1998
- 1998-11-03 MY MYPI98004994A patent/MY133169A/en unknown
- 1998-11-03 NZ NZ332622A patent/NZ332622A/xx unknown
- 1998-11-17 PE PE1998001116A patent/PE133499A1/es not_active Application Discontinuation
- 1998-11-23 DK DK98122218T patent/DK0922703T3/da active
- 1998-11-23 SI SI9830350T patent/SI0922703T1/xx unknown
- 1998-11-23 DE DE59806523T patent/DE59806523D1/de not_active Expired - Fee Related
- 1998-11-23 PT PT98122218T patent/PT922703E/pt unknown
- 1998-11-23 ES ES98122218T patent/ES2189072T3/es not_active Expired - Lifetime
- 1998-11-23 EP EP98122218A patent/EP0922703B1/de not_active Expired - Lifetime
- 1998-11-23 AT AT98122218T patent/ATE229016T1/de not_active IP Right Cessation
- 1998-12-03 AR ARP980106155A patent/AR017800A1/es unknown
- 1998-12-09 BR BR9805437-6A patent/BR9805437A/pt not_active IP Right Cessation
- 1998-12-10 CO CO98073439A patent/CO4990950A1/es unknown
- 1998-12-10 UY UY25296A patent/UY25296A1/es not_active Application Discontinuation
- 1998-12-10 SK SK1699-98A patent/SK283366B6/sk not_active IP Right Cessation
- 1998-12-10 ZA ZA9811346A patent/ZA9811346B/xx unknown
- 1998-12-10 CZ CZ19984076A patent/CZ294990B6/cs not_active IP Right Cessation
- 1998-12-11 US US09/208,990 patent/US6013809A/en not_active Expired - Fee Related
- 1998-12-11 NO NO985818A patent/NO985818L/no not_active Application Discontinuation
- 1998-12-11 PL PL330257A patent/PL194934B1/pl not_active IP Right Cessation
- 1998-12-11 IL IL12751898A patent/IL127518A/xx not_active IP Right Cessation
- 1998-12-11 AU AU97073/98A patent/AU747979B2/en not_active Ceased
- 1998-12-11 CN CNB981253180A patent/CN100376564C/zh not_active Expired - Fee Related
- 1998-12-11 KR KR1019980054315A patent/KR19990062982A/ko not_active Ceased
- 1998-12-11 HU HU9802886A patent/HU226014B1/hu not_active IP Right Cessation
- 1998-12-11 JP JP10353219A patent/JPH11246547A/ja active Pending
- 1998-12-11 CA CA002256007A patent/CA2256007C/en not_active Expired - Fee Related
- 1998-12-15 RU RU98122335/04A patent/RU2197484C2/ru not_active IP Right Cessation
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