SI0787726T1 - Novel compound, process for producing the same, and antitumor agent - Google Patents

Novel compound, process for producing the same, and antitumor agent

Info

Publication number
SI0787726T1
SI0787726T1 SI9530567T SI9530567T SI0787726T1 SI 0787726 T1 SI0787726 T1 SI 0787726T1 SI 9530567 T SI9530567 T SI 9530567T SI 9530567 T SI9530567 T SI 9530567T SI 0787726 T1 SI0787726 T1 SI 0787726T1
Authority
SI
Slovenia
Prior art keywords
hydrogen atom
producing
same
group
lower alkyl
Prior art date
Application number
SI9530567T
Other languages
English (en)
Slovenian (sl)
Inventor
Kyoji Tomita
Katsumi Chiba
Shigeki Kashimoto
Koh-Ichiro Shibamori
Yasunori Tsuzuki
Original Assignee
Dainippon Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co., Ltd. filed Critical Dainippon Pharmaceutical Co., Ltd.
Publication of SI0787726T1 publication Critical patent/SI0787726T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SI9530567T 1994-06-14 1995-06-06 Novel compound, process for producing the same, and antitumor agent SI0787726T1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP15657894 1994-06-14
JP19792194 1994-07-28
JP30691494 1994-11-15
JP33995694 1994-12-28
JP8170595 1995-03-13
PCT/JP1995/001110 WO1995034559A1 (en) 1994-06-14 1995-06-06 Novel compound, process for producing the same, and antitumor agent
EP95920265A EP0787726B1 (en) 1994-06-14 1995-06-06 Novel compound, process for producing the same, and antitumor agent

Publications (1)

Publication Number Publication Date
SI0787726T1 true SI0787726T1 (en) 2002-04-30

Family

ID=27524935

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9530567T SI0787726T1 (en) 1994-06-14 1995-06-06 Novel compound, process for producing the same, and antitumor agent

Country Status (27)

Country Link
US (1) US5817669A (cs)
EP (1) EP0787726B1 (cs)
JP (1) JP3391796B2 (cs)
KR (1) KR100350921B1 (cs)
CN (1) CN1053668C (cs)
AT (1) ATE209645T1 (cs)
AU (1) AU679859B2 (cs)
BR (1) BR9508037A (cs)
CA (1) CA2192824C (cs)
CZ (1) CZ292631B6 (cs)
DE (1) DE69524251T2 (cs)
DK (1) DK0787726T3 (cs)
ES (1) ES2163512T3 (cs)
FI (1) FI112485B (cs)
HK (1) HK1000495A1 (cs)
HU (1) HU220072B (cs)
MX (1) MX9606331A (cs)
NO (1) NO307255B1 (cs)
NZ (1) NZ287139A (cs)
PL (1) PL181867B1 (cs)
PT (1) PT787726E (cs)
RO (1) RO117793B1 (cs)
RU (1) RU2151770C1 (cs)
SI (1) SI0787726T1 (cs)
SK (1) SK281341B6 (cs)
TW (1) TW319769B (cs)
WO (1) WO1995034559A1 (cs)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20040309A2 (en) 2001-09-26 2006-05-31 Bayer Pharmaceuticals Corporation 1,6-nafthyridine derivatives as antidiabetics
US6802423B2 (en) * 2002-02-20 2004-10-12 Trans Global Foods, Inc. Disposable food delivery apparatus
US7163948B2 (en) * 2003-04-07 2007-01-16 Cylene Pharmaceuticals, Inc. Heterocyclic substituted 1,4-dihydri-4ox9-1,8-naphthyridine analogs
CA2536429C (en) * 2003-09-10 2012-02-14 Kyorin Pharmaceutical Co., Ltd. 7-(4-substituted-3-cyclopropylaminomethyl-1-pyrrolidinyl) quinolonecarboxylic acid derivative
DE10352979A1 (de) * 2003-11-13 2005-06-09 Merck Patent Gmbh Pyridopyrimidinone
AU2013201203C1 (en) * 2004-03-15 2015-04-23 Sumitomo Dainippon Pharma Co., Ltd. Sns-595 and methods of using the same
DE602005025738D1 (de) * 2004-03-15 2011-02-17 Dainippon Sumitomo Pharma Co Pharmazeutische zusammensetzung enthaltend sns-595 und deren verwendungen
RU2405782C2 (ru) * 2004-10-14 2010-12-10 Ф.Хоффманн-Ля Рош Аг Хиназолинилметилентиазолиноны в качестве cdk-1 ингибиторов
US7268231B2 (en) * 2004-10-14 2007-09-11 Hoffmann-La Roche Inc. 1,5-Naphthyridine azolinone
RU2420524C2 (ru) * 2005-05-19 2011-06-10 Дайити Санкио Компани, Лимитед Производные три- или тетра-замещенного-3-аминопирролидина
US7563805B2 (en) * 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
CA2619663A1 (en) * 2005-08-19 2007-02-22 Cylene Pharmaceuticals, Inc. Human ribosomal dna(rdna) and ribosomal rna (rrna) nucleic acids and uses thereof
RU2428983C2 (ru) * 2005-09-02 2011-09-20 Санесис Фармасьютикалз, Инк. Способы применения (+)-1,4-дигидро-7-[(3s,4s)-3-метокси-4-(метиламино)-1-пирролидинил]-4-оксо-1-(2-тиазолил)-1,8-нафтиридин-3-карбоновой кислоты для лечения рака
CN104873502A (zh) * 2005-09-02 2015-09-02 逊尼希思制药公司 使用(+)-1,4-二氢-7-[(3s,4s)-3-甲氧基-4-(甲氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸治疗癌症的方法
EP1931339B1 (en) * 2005-09-02 2018-05-16 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
KR20170118936A (ko) * 2005-09-02 2017-10-25 선에시스 파마슈티컬스 인코포레이티드 암 치료를 위한 (＋)-1,4-디히드로-7-［(3ｓ,4ｓ)-3-메톡시-4-(메틸아미노)-1-피롤리디닐］-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카르복실산의 사용 방법
AU2013219242C1 (en) * 2005-09-02 2016-09-22 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
US8580814B2 (en) * 2006-04-03 2013-11-12 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
TW200800983A (en) 2005-09-14 2008-01-01 Janssen Pharmaceutica Nv 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of C-FMS kinase
US7642270B2 (en) 2005-09-14 2010-01-05 Janssen Pharmaceutica N.V. 5-oxo-5,8-dihydro-pyrido-pyrimidine as inhibitors of c-fms kinase
WO2007033232A1 (en) * 2005-09-14 2007-03-22 Janssen Pharmaceutica, N.V. 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of c-fms kinase
EP2354138A1 (en) * 2006-06-12 2011-08-10 Sunesis Pharmaceuticals, Inc. Compounds and compositions for treatment of cancer
WO2008016678A2 (en) * 2006-08-01 2008-02-07 Sunesis Pharmaceuticals, Inc. Pharmaceutical dosage forms for (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
MX344865B (es) * 2006-08-02 2016-12-19 Sunesis Pharmaceuticals Inc Metodos para usar acido (+)-1,4-dihidro-7-[(3s,4s)-3-metoxi-4-(met ilamino)-1-pirrolidinil]-4-oxo-1(2-tiazolil)-1,8-naftiridina-3-ca rboxilico para el tratamiento de ciertos padecimientos hematologicos.
JP6029808B2 (ja) * 2007-10-22 2016-11-24 サネシス ファーマシューティカルズ， インコーポレイテッド 併用療法における（＋）−１，４−ジヒドロ−７−［（３ｓ，４ｓ）−３−メトキシ−４−（メチルアミノ）−１−ピロリジニル］−４−オキソ−１−（２−チアゾリル）−１，８−ナフチリジン−３−カルボン酸の使用方法
EP2249831A2 (en) * 2007-12-10 2010-11-17 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-ý(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl¨-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of antecedent hematologic disorders
KR20170090535A (ko) 2008-12-31 2017-08-07 선에시스 파마슈티컬스 인코포레이티드 (＋)-1,4-다이하이드로-7-［(3ｓ,4ｓ)-3-메톡시-4-(메틸아미노)-1-피롤리딘일］-4-옥소-1-(2-티아졸릴)-1,8-나프티리딘-3-카복실산의 제조 방법
SG173855A1 (en) 2009-02-27 2011-09-29 Sunesis Pharmaceuticals Inc Methods of using sns-595 for treatment of cancer subjects with reduced brca2 activity
UA110465C2 (en) 2009-09-04 2016-01-12 Sunesis Pharmaceutecals Inc Stable sns-595 composition
TW201120037A (en) * 2009-10-26 2011-06-16 Sunesis Pharmaceuticals Inc Compounds and methods for treatment of cancer
CN108329246B (zh) * 2011-05-13 2021-02-26 阵列生物制药公司 作为trka激酶抑制剂的吡咯烷基脲和吡咯烷基硫脲化合物
CN103497186B (zh) * 2013-09-24 2015-02-25 浙江司太立制药股份有限公司 含有烷氧亚氨基取代的萘啶酮羧酸衍生物及其制备方法
CN110520422B (zh) * 2017-03-24 2023-09-05 涌永制药株式会社 新型吡啶酮羧酸衍生物或其盐

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3988463A (en) * 1974-05-06 1976-10-26 Merck & Co., Inc. Method of preventing metastasis of H. Ep. No. 3
US4384001A (en) * 1978-12-21 1983-05-17 Gosalvez Mario Treatment of tumors with thiazolidine-4-carboxylic acid
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
DE3577089D1 (de) * 1984-01-26 1990-05-17 Abbott Lab Antibakterielle chinolinderivate.
NZ210847A (en) * 1984-01-26 1988-02-29 Abbott Lab Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions
JPS61152682A (ja) * 1984-12-27 1986-07-11 Dainippon Pharmaceut Co Ltd ピリドンカルボン酸誘導体、そのエステルおよびその塩
JPS61251667A (ja) * 1985-04-30 1986-11-08 Otsuka Pharmaceut Co Ltd ベンゾヘテロ環化合物
IL79110A0 (en) * 1985-06-13 1986-09-30 Schering Corp Polycyclic quinoline,naphthyridine and pyrazinopyridine derivatives
US4851425A (en) * 1985-06-14 1989-07-25 The Upjohn Company Cyclopentapyrazole and tetrahydroindazole compounds and their use as anti-inflammatory and anti-allergic agents
JPS6233176A (ja) * 1985-08-05 1987-02-13 Toyama Chem Co Ltd １，４−ジヒドロ−４−オキソナフチリジン誘導体およびその塩
JP2704428B2 (ja) * 1988-06-15 1998-01-26 富山化学工業株式会社 キノロンカルボン酸誘導体またはその塩
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
JPH06233176A (ja) * 1993-01-29 1994-08-19 Sony Corp ビデオカメラ

Also Published As

Publication number Publication date
NO307255B1 (no) 2000-03-06
KR100350921B1 (ko) 2002-11-18
PL181867B1 (pl) 2001-09-28
HU9603455D0 (en) 1997-02-28
ATE209645T1 (de) 2001-12-15
CA2192824A1 (en) 1995-12-21
SK157496A3 (en) 1997-08-06
NZ287139A (en) 1997-07-27
MX9606331A (es) 1997-03-29
EP0787726A1 (en) 1997-08-06
FI965020A0 (fi) 1996-12-13
CA2192824C (en) 2006-11-07
PL317726A1 (en) 1997-04-28
TW319769B (cs) 1997-11-11
HU220072B (hu) 2001-10-28
DE69524251D1 (de) 2002-01-10
AU2576795A (en) 1996-01-05
NO965305D0 (no) 1996-12-11
CN1053668C (zh) 2000-06-21
US5817669A (en) 1998-10-06
CZ292631B6 (cs) 2003-11-12
CZ364396A3 (en) 1997-06-11
ES2163512T3 (es) 2002-02-01
NO965305L (no) 1997-02-04
RO117793B1 (ro) 2002-07-30
SK281341B6 (sk) 2001-02-12
WO1995034559A1 (en) 1995-12-21
AU679859B2 (en) 1997-07-10
EP0787726B1 (en) 2001-11-28
RU2151770C1 (ru) 2000-06-27
HK1000495A1 (en) 2002-07-19
BR9508037A (pt) 1997-09-16
JP3391796B2 (ja) 2003-03-31
DE69524251T2 (de) 2002-07-11
EP0787726A4 (cs) 1997-08-06
PT787726E (pt) 2002-04-29
HUT75777A (en) 1997-05-28
CN1158614A (zh) 1997-09-03
FI112485B (fi) 2003-12-15
FI965020A7 (fi) 1996-12-16
DK0787726T3 (da) 2002-02-11

Similar Documents

Publication Publication Date Title
AU679859B2 (en) Novel compound, process for producing the same, and antitumor agent
EP0945452A4 (en) SUGAR COMPOSITIONS, GELLING AGENTS, GELLING AGENT COMPOSITIONS, METHODS OF PREPARING SAME, AND GEL COMPOSITIONS
HUT54685A (en) Process for producing condensed heterocyclic compounds, salts and intermediates, and fungicide compositions containing them
ZA88309B (en) 3(2h)pyridazinone,process for its preparation and antagonistic agent against srs-a containing it
HUT59378A (en) Process for producing urea derivatives and pharmaceutical compositions comprising such compounds
HUT47099A (en) Process for producing pyridine derivatives and pharmaceutical compositions comprising such compounds
AU7928791A (en) Bisphophonic acid derivatives, their production and use
NZ222185A (en) N-substituted methanesulphonamide derivatives, and anticancer compositions containing such
HUT52521A (en) Process for producing estremustine-esters and pharmaceutical compositions containing them as active components
ATE148128T1 (de) Anthracyclinglycosid-derivate und verfahren zu ihrer herstellung
AU1589695A (en) Bicyclic amino group-substituted pyridonecarboxylic acid derivatives, esters thereof and salts thereof, and bicyclic amines useful as intermediates thereof
HUT59083A (en) Improved process for producing 4-methyl-sulfonyl-benzoic acid derivatives
EP0844247A4 (en) METHOD FOR PRODUCING 3-NORCEPHEMIC COMPOUNDS
EP0827961A4 (en) METHOD FOR PRODUCING BETA-LACTAM COMPOUNDS
ZA869742B (en) Novel pregnane derivatives,processes for their preparation and pharmaceutical compositions containing same
PT71432A (en) Clavulanic acid derivatives a process for their preparation and their use
HU906407D0 (en) Process for producing new inozine- and guanozine derivatives and pharmaceutical compositions containing them as active components
MY104164A (en) Heterocyclic compounds.