SI0770613T1 - Substituted Imidazolidin-2,4-dione derivatives as immunomodulators - Google Patents
Substituted Imidazolidin-2,4-dione derivatives as immunomodulatorsInfo
- Publication number
- SI0770613T1 SI0770613T1 SI9630066T SI9630066T SI0770613T1 SI 0770613 T1 SI0770613 T1 SI 0770613T1 SI 9630066 T SI9630066 T SI 9630066T SI 9630066 T SI9630066 T SI 9630066T SI 0770613 T1 SI0770613 T1 SI 0770613T1
- Authority
- SI
- Slovenia
- Prior art keywords
- immunomodulators
- dione derivatives
- substituted imidazolidin
- imidazolidin
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19540027A DE19540027A1 (de) | 1995-10-27 | 1995-10-27 | Substituierte Imidazolidin-2,4-dion-Verbindungen als pharmazeutische Wirkstoffe |
EP96116069A EP0770613B1 (fr) | 1995-10-27 | 1996-10-08 | Dérivés substitués de l'imidazolidin-2,4 dione comme immunomodulateurs |
Publications (1)
Publication Number | Publication Date |
---|---|
SI0770613T1 true SI0770613T1 (en) | 1999-10-31 |
Family
ID=7775931
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI9630066T SI0770613T1 (en) | 1995-10-27 | 1996-10-08 | Substituted Imidazolidin-2,4-dione derivatives as immunomodulators |
Country Status (23)
Country | Link |
---|---|
US (1) | US6004963A (fr) |
EP (1) | EP0770613B1 (fr) |
JP (1) | JPH09188677A (fr) |
KR (1) | KR100445539B1 (fr) |
CN (1) | CN1097050C (fr) |
AR (1) | AR004517A1 (fr) |
AT (1) | ATE181072T1 (fr) |
AU (1) | AU707751B2 (fr) |
CA (1) | CA2188908A1 (fr) |
CO (1) | CO4750655A1 (fr) |
DE (2) | DE19540027A1 (fr) |
DK (1) | DK0770613T3 (fr) |
ES (1) | ES2135148T3 (fr) |
GR (1) | GR3030558T3 (fr) |
HK (1) | HK1010367A1 (fr) |
HU (1) | HU222120B1 (fr) |
IL (1) | IL119488A (fr) |
MX (1) | MX9605023A (fr) |
PE (1) | PE20011055A1 (fr) |
PL (1) | PL184446B1 (fr) |
RU (1) | RU2163603C2 (fr) |
SI (1) | SI0770613T1 (fr) |
ZA (1) | ZA968956B (fr) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19732928C2 (de) * | 1997-07-31 | 2000-05-18 | Gruenenthal Gmbh | Verwendung substituierter Imidazolidin-2,4-dion-Verbindungen als Schmerzmittel |
DE19917961A1 (de) | 1999-04-21 | 2000-10-26 | Degussa | Verfahren zur Herstellung von Aminosäurederivaten |
US6350763B1 (en) * | 1999-07-21 | 2002-02-26 | Boehringer Ingelheim Pharmaceuticals, Inc. | Small molecules useful in the treatment of inflammation disease |
IL152961A0 (en) * | 2000-05-31 | 2003-06-24 | Tanabe Seiyaku Co | Inhibitors of alpha beta 2 mediated cell adhesion |
US7354933B2 (en) | 2003-01-31 | 2008-04-08 | Aventis Pharma Sa | Cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors |
FR2850652B1 (fr) * | 2003-01-31 | 2008-05-30 | Aventis Pharma Sa | Nouveaux derives d'uree cyclique, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de kinases |
WO2005090316A1 (fr) * | 2004-03-12 | 2005-09-29 | Wyeth | Hydantoines a activite modulatrice de la rnase |
EP1621535A1 (fr) * | 2004-07-27 | 2006-02-01 | Aventis Pharma S.A. | Dérivés substitués d'urée cyclique, leur préparation et leur utilisation pharmaceutique comme inhibiteurs de kinases |
EP1621536A1 (fr) * | 2004-07-27 | 2006-02-01 | Aventis Pharma S.A. | Dérivés d'urées cycliques aminés, leur préparation et utilisation pharmaceutique en tant qu'inhibiteurs de Kinase |
EP1621539A1 (fr) * | 2004-07-27 | 2006-02-01 | Aventis Pharma S.A. | Dérivées d'urée cyclique substitués par un heterocycle, leur prépration et leur utilisation pharmaceutique comee inhibiteurs de kinases |
US7709517B2 (en) | 2005-05-13 | 2010-05-04 | The Regents Of The University Of California | Diarylhydantoin compounds |
FR2896503B1 (fr) * | 2006-01-23 | 2012-07-13 | Aventis Pharma Sa | Nouveaux derives soufres d'uree cyclique, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de kinases |
FR2896504B1 (fr) * | 2006-01-23 | 2012-07-13 | Aventis Pharma Sa | Nouveaux derives d'uree cyclique, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de kinases |
DK2656841T3 (en) | 2006-03-27 | 2016-12-05 | Univ California | Androgen receptor MODULATOR FOR THE TREATMENT OF PROSTATE CANCER AND androgen receptor-ASSOCIATED DISEASES |
AU2016201061B2 (en) * | 2006-03-27 | 2017-03-02 | The Regents Of The University Of California | Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases |
AU2012241184B2 (en) * | 2006-03-27 | 2016-01-07 | The Regents Of The University Of California | Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases |
AU2013205325B2 (en) * | 2006-03-27 | 2016-03-24 | The Regents Of The University Of California | Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases |
RU2449993C2 (ru) | 2006-03-29 | 2012-05-10 | Те Риджентс Оф Те Юниверсити Оф Калифорния | Диарилтиогидантоиновые соединения |
US7649007B2 (en) * | 2006-08-15 | 2010-01-19 | Wyeth Llc | Oxazolidine derivatives as PR modulators |
US7538107B2 (en) | 2006-08-15 | 2009-05-26 | Wyeth | Oxazinan-2-one derivatives useful as PR modulators |
TW200815428A (en) | 2006-08-15 | 2008-04-01 | Wyeth Corp | Oxazolidone derivatives as PR modulators |
WO2008021309A1 (fr) * | 2006-08-15 | 2008-02-21 | Wyeth | Dérivés d'imidazolidin-2-one utiles en tant que modulateurs pr |
EP2069335B1 (fr) * | 2006-09-08 | 2012-12-26 | Actelion Pharmaceuticals Ltd. | Dérivés de pyridin-3-yle en tant qu'agents immunomodulateurs |
CA2966280A1 (fr) | 2007-10-26 | 2009-04-30 | The Regents Of The University Of California | Composes de diaryl-hydantoine |
BRPI0913966A2 (pt) * | 2008-06-27 | 2015-11-17 | Novartis Ag | compostos orgânicos |
JP5634506B2 (ja) | 2009-05-12 | 2014-12-03 | ジャンセン ファーマシューティカルズ, インコーポレイテッド | 1,2,3−トリアゾロ[4,3−a]ピリジン誘導体ならびに神経障害および精神障害の治療または予防のためのその使用 |
WO2011103202A2 (fr) | 2010-02-16 | 2011-08-25 | Aragon Pharmaceuticals, Inc. | Modulateurs du récepteur des androgènes et leurs utilisations |
KR20220025231A (ko) | 2012-09-26 | 2022-03-03 | 아라곤 파마슈티컬스, 인코포레이티드 | 비전이성 거세 저항성 전립선암 치료용 항안드로겐 |
JOP20200097A1 (ar) | 2013-01-15 | 2017-06-16 | Aragon Pharmaceuticals Inc | معدل مستقبل أندروجين واستخداماته |
TWI726969B (zh) | 2016-01-11 | 2021-05-11 | 比利時商健生藥品公司 | 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物 |
KR20200070334A (ko) | 2017-10-16 | 2020-06-17 | 아라곤 파마슈티컬스, 인코포레이티드 | 비-전이성 거세-저항성 전립선암의 치료를 위한 항-안드로겐 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0091596B1 (fr) * | 1982-04-08 | 1991-09-11 | Shell Internationale Researchmaatschappij B.V. | Hydantoins, préparation et application |
US4746669A (en) * | 1985-12-23 | 1988-05-24 | Merck & Co., Inc. | Substituted thiazoles as immunoregulants |
JPH02101065A (ja) * | 1988-10-06 | 1990-04-12 | Tanabe Seiyaku Co Ltd | イミダゾリン誘導体及びその製法 |
KR930703262A (ko) * | 1990-11-06 | 1993-11-29 | 스튜어트 알. 슈터 | 이미다졸리디논 화합물 |
IL110296A (en) * | 1993-07-16 | 1999-12-31 | Smithkline Beecham Corp | Imidazole compounds process for their preparation and pharmaceutical compositions containing them |
US7466669B2 (en) * | 2003-11-14 | 2008-12-16 | Telefonaktiebolaget Lm Ericsson (Publ) | Reverse link scheduler for CDMA networks |
-
1995
- 1995-10-27 DE DE19540027A patent/DE19540027A1/de not_active Withdrawn
-
1996
- 1996-09-26 PE PE1996000688A patent/PE20011055A1/es not_active Application Discontinuation
- 1996-10-04 CO CO96052910A patent/CO4750655A1/es unknown
- 1996-10-08 DE DE59602155T patent/DE59602155D1/de not_active Expired - Fee Related
- 1996-10-08 SI SI9630066T patent/SI0770613T1/xx not_active IP Right Cessation
- 1996-10-08 DK DK96116069T patent/DK0770613T3/da active
- 1996-10-08 EP EP96116069A patent/EP0770613B1/fr not_active Expired - Lifetime
- 1996-10-08 AT AT96116069T patent/ATE181072T1/de not_active IP Right Cessation
- 1996-10-08 ES ES96116069T patent/ES2135148T3/es not_active Expired - Lifetime
- 1996-10-14 AU AU68181/96A patent/AU707751B2/en not_active Ceased
- 1996-10-16 AR ARP960104778A patent/AR004517A1/es unknown
- 1996-10-22 MX MX9605023A patent/MX9605023A/es unknown
- 1996-10-24 HU HU9602932A patent/HU222120B1/hu not_active IP Right Cessation
- 1996-10-24 JP JP8282701A patent/JPH09188677A/ja active Pending
- 1996-10-24 ZA ZA968956A patent/ZA968956B/xx unknown
- 1996-10-25 CA CA002188908A patent/CA2188908A1/fr not_active Abandoned
- 1996-10-25 IL IL11948896A patent/IL119488A/xx not_active IP Right Cessation
- 1996-10-25 RU RU96121181/04A patent/RU2163603C2/ru not_active IP Right Cessation
- 1996-10-25 PL PL96316706A patent/PL184446B1/pl not_active IP Right Cessation
- 1996-10-25 US US08/738,232 patent/US6004963A/en not_active Expired - Fee Related
- 1996-10-25 KR KR1019960048441A patent/KR100445539B1/ko not_active IP Right Cessation
- 1996-10-26 CN CN96121960A patent/CN1097050C/zh not_active Expired - Fee Related
-
1998
- 1998-09-25 HK HK98110963A patent/HK1010367A1/xx not_active IP Right Cessation
-
1999
- 1999-06-17 GR GR990401639T patent/GR3030558T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
HU222120B1 (hu) | 2003-04-28 |
CO4750655A1 (es) | 1999-03-31 |
IL119488A0 (en) | 1997-01-10 |
PL316706A1 (en) | 1997-04-28 |
PE20011055A1 (es) | 2001-12-29 |
IL119488A (en) | 2001-01-11 |
PL184446B1 (pl) | 2002-10-31 |
AR004517A1 (es) | 1998-12-16 |
GR3030558T3 (en) | 1999-10-29 |
EP0770613A1 (fr) | 1997-05-02 |
DK0770613T3 (da) | 1999-12-13 |
RU2163603C2 (ru) | 2001-02-27 |
HU9602932D0 (en) | 1996-12-30 |
MX9605023A (es) | 1997-06-28 |
AU6818196A (en) | 1997-05-01 |
CA2188908A1 (fr) | 1997-04-28 |
JPH09188677A (ja) | 1997-07-22 |
EP0770613B1 (fr) | 1999-06-09 |
DE59602155D1 (de) | 1999-07-15 |
US6004963A (en) | 1999-12-21 |
HUP9602932A2 (hu) | 1998-07-28 |
ES2135148T3 (es) | 1999-10-16 |
CN1097050C (zh) | 2002-12-25 |
AU707751B2 (en) | 1999-07-22 |
HK1010367A1 (en) | 1999-06-17 |
KR970021076A (ko) | 1997-05-28 |
KR100445539B1 (ko) | 2004-12-30 |
HUP9602932A3 (en) | 1998-08-28 |
DE19540027A1 (de) | 1997-04-30 |
CN1152573A (zh) | 1997-06-25 |
ZA968956B (en) | 1997-05-29 |
ATE181072T1 (de) | 1999-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KO00 | Lapse of patent |
Effective date: 20080528 |