SI0754680T1 - 4-Fluoroalkyl-substituted benzoylguanidines, process for their preparation, their use as medicament as well as medicaments containing them - Google Patents

4-Fluoroalkyl-substituted benzoylguanidines, process for their preparation, their use as medicament as well as medicaments containing them

Info

Publication number
SI0754680T1
SI0754680T1 SI9630424T SI9630424T SI0754680T1 SI 0754680 T1 SI0754680 T1 SI 0754680T1 SI 9630424 T SI9630424 T SI 9630424T SI 9630424 T SI9630424 T SI 9630424T SI 0754680 T1 SI0754680 T1 SI 0754680T1
Authority
SI
Slovenia
Prior art keywords
fluoroalkyl
medicament
preparation
well
medicaments containing
Prior art date
Application number
SI9630424T
Other languages
English (en)
Slovenian (sl)
Inventor
Andreas Dr. Weichert
Joachim Dr. Brendel
Heinz-Werner Dr. Kleemann
Hans Jochen Dr. Lang
Jan-Robert Dr. Schwark
Wolfgang Dr. Scholz
Udo Dr. Albus
Original Assignee
Hoechst Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of SI0754680T1 publication Critical patent/SI0754680T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/52—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton the carbon skeleton being further substituted by doubly-bound oxygen atoms
    • C07C309/53—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton the carbon skeleton being further substituted by doubly-bound oxygen atoms the carbon skeleton containing carbon atoms of quinone rings
    • C07C309/54—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton the carbon skeleton being further substituted by doubly-bound oxygen atoms the carbon skeleton containing carbon atoms of quinone rings at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SI9630424T 1995-07-19 1996-07-15 4-Fluoroalkyl-substituted benzoylguanidines, process for their preparation, their use as medicament as well as medicaments containing them SI0754680T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19526381A DE19526381A1 (de) 1995-07-19 1995-07-19 4-Fluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP96111359A EP0754680B1 (de) 1995-07-19 1996-07-15 4-Fluoralkyl-substituierte Benzoylguandine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
SI0754680T1 true SI0754680T1 (en) 2002-04-30

Family

ID=7767257

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9630424T SI0754680T1 (en) 1995-07-19 1996-07-15 4-Fluoroalkyl-substituted benzoylguanidines, process for their preparation, their use as medicament as well as medicaments containing them

Country Status (28)

Country Link
US (1) US6156800A (ru)
EP (1) EP0754680B1 (ru)
JP (1) JPH0931045A (ru)
KR (1) KR970006282A (ru)
CN (1) CN1072644C (ru)
AR (1) AR003461A1 (ru)
AT (1) ATE211463T1 (ru)
AU (1) AU704649B2 (ru)
BR (1) BR9603112A (ru)
CA (1) CA2181515A1 (ru)
CZ (1) CZ291240B6 (ru)
DE (2) DE19526381A1 (ru)
DK (1) DK0754680T3 (ru)
ES (1) ES2170183T3 (ru)
HR (1) HRP960343B1 (ru)
HU (1) HUP9601976A3 (ru)
IL (1) IL118887A (ru)
MX (1) MX9602841A (ru)
NO (1) NO306612B1 (ru)
NZ (1) NZ299015A (ru)
PL (1) PL183906B1 (ru)
PT (1) PT754680E (ru)
RU (1) RU2165412C2 (ru)
SI (1) SI0754680T1 (ru)
SK (1) SK281604B6 (ru)
TR (1) TR199600588A2 (ru)
TW (1) TW462960B (ru)
ZA (1) ZA966106B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19526381A1 (de) * 1995-07-19 1997-01-23 Hoechst Ag 4-Fluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
CA2337087C (en) * 2000-03-08 2006-06-06 Canon Kabushiki Kaisha Magnetic toner, process for production thereof, and image forming method, apparatus and process cartridge using the toner
DE10222192A1 (de) * 2002-05-18 2003-11-27 Aventis Pharma Gmbh Pentafluorsulfuranyl-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
US7375138B2 (en) * 2002-05-18 2008-05-20 Sanofi-Aventis Deutschland Gmbh Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them
US20050124666A1 (en) * 2003-11-13 2005-06-09 Aventis Pharma Deutschland Gmbh Pentafluorosulfanylbenzoylguanidines, process for their preparation, use as a medicament or diagnostic aid, and medicament comprising same
OA13285A (en) * 2003-11-13 2007-01-31 Sanofi Aventis Deutschland Pentafluorosulfanyl benzoylguanidines, method for their production, their use as medicaments or diagnostic agents and medicament containing the same.
WO2021026402A1 (en) 2019-08-07 2021-02-11 Abbott Laboratories Chemiluminescent compounds for multiplexing

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3780027A (en) * 1970-04-29 1973-12-18 Merck & Co Inc Anthranilic acid derivatives
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
DK0556674T3 (da) * 1992-02-15 1996-10-14 Hoechst Ag 3,5-Substituerede benzoylguanidiner med antiarytmisk virkning og inhiberende virkning på celleproliferation
ATE157351T1 (de) * 1993-02-20 1997-09-15 Hoechst Ag Substituierte benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament, als inhibitoren des zellulären na+/h+-austauschs oder als diagnostikum sowie sie enthaltendes medikament
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19526381A1 (de) * 1995-07-19 1997-01-23 Hoechst Ag 4-Fluoralkyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
NO962999L (no) 1997-01-20
JPH0931045A (ja) 1997-02-04
DE59608533D1 (de) 2002-02-07
AR003461A1 (es) 1998-08-05
SK93896A3 (en) 1997-05-07
ES2170183T3 (es) 2002-08-01
TW462960B (en) 2001-11-11
HUP9601976A3 (en) 1998-07-28
CN1072644C (zh) 2001-10-10
AU6056396A (en) 1997-01-23
PL314278A1 (en) 1997-01-20
HUP9601976A2 (en) 1997-09-29
PL183906B1 (pl) 2002-07-31
IL118887A0 (en) 1996-10-31
HRP960343A2 (en) 1998-02-28
BR9603112A (pt) 1998-05-05
MX9602841A (es) 1997-01-31
CZ212096A3 (en) 1997-04-16
EP0754680A1 (de) 1997-01-22
TR199600588A2 (tr) 1997-03-21
RU2165412C2 (ru) 2001-04-20
EP0754680B1 (de) 2002-01-02
US6156800A (en) 2000-12-05
CZ291240B6 (cs) 2003-01-15
PT754680E (pt) 2002-06-28
HU9601976D0 (en) 1996-09-30
DE19526381A1 (de) 1997-01-23
SK281604B6 (sk) 2001-05-10
NO962999D0 (no) 1996-07-18
IL118887A (en) 2002-07-25
NZ299015A (en) 1997-08-22
HRP960343B1 (en) 2002-02-28
CA2181515A1 (en) 1997-01-20
CN1143076A (zh) 1997-02-19
DK0754680T3 (da) 2002-04-15
KR970006282A (ko) 1997-02-19
ATE211463T1 (de) 2002-01-15
AU704649B2 (en) 1999-04-29
NO306612B1 (no) 1999-11-29
ZA966106B (en) 1997-02-03

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