SG53279A1 - Fibrin-specific antibody for use as an antithrombotic agent - Google Patents

Fibrin-specific antibody for use as an antithrombotic agent

Info

Publication number
SG53279A1
SG53279A1 SG1996009046A SG1996009046A SG53279A1 SG 53279 A1 SG53279 A1 SG 53279A1 SG 1996009046 A SG1996009046 A SG 1996009046A SG 1996009046 A SG1996009046 A SG 1996009046A SG 53279 A1 SG53279 A1 SG 53279A1
Authority
SG
Singapore
Prior art keywords
fibrin
specific antibody
antithrombotic agent
antithrombotic
agent
Prior art date
Application number
SG1996009046A
Other languages
English (en)
Inventor
Paul E Gargan
Original Assignee
American Biogenetic Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Biogenetic Sciences filed Critical American Biogenetic Sciences
Publication of SG53279A1 publication Critical patent/SG53279A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG1996009046A 1994-02-24 1995-02-21 Fibrin-specific antibody for use as an antithrombotic agent SG53279A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/204,015 US5487892A (en) 1994-02-24 1994-02-24 Method for treating thrombotic disease using a fibrin specific monoclonal antibody

Publications (1)

Publication Number Publication Date
SG53279A1 true SG53279A1 (en) 1998-09-28

Family

ID=22756260

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996009046A SG53279A1 (en) 1994-02-24 1995-02-21 Fibrin-specific antibody for use as an antithrombotic agent

Country Status (26)

Country Link
US (1) US5487892A (xx)
EP (1) EP0749320A4 (xx)
JP (1) JPH09509429A (xx)
KR (1) KR970701063A (xx)
CN (1) CN1146157A (xx)
AU (1) AU708897B2 (xx)
BG (1) BG62476B1 (xx)
BR (1) BR9506949A (xx)
CA (1) CA2183953A1 (xx)
CZ (1) CZ246496A3 (xx)
FI (1) FI963288A0 (xx)
GE (1) GEP20002257B (xx)
HU (1) HUT76536A (xx)
LT (1) LT4192B (xx)
LV (1) LV11784B (xx)
MD (1) MD1521G2 (xx)
MX (1) MX9603602A (xx)
NO (1) NO963497L (xx)
NZ (1) NZ281481A (xx)
PL (1) PL316005A1 (xx)
RU (1) RU2152801C2 (xx)
SG (1) SG53279A1 (xx)
SK (1) SK108496A3 (xx)
TJ (1) TJ301B (xx)
UA (1) UA41984C2 (xx)
WO (1) WO1995022986A1 (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5582862A (en) * 1988-04-04 1996-12-10 General Hospital Corporation Antibodies that bind to α2-antiplasmin crosslinked to fibrin which do not inhibit plasma α2-antiplasmin
US5453359A (en) * 1988-06-13 1995-09-26 American Biogenetic Sciences, Inc. Immunoassay and kit for in vitro detection of soluble DesAABB fibrin polymers
US5817768A (en) * 1995-06-07 1998-10-06 The New York Blood Center, Inc. Monospecific antibodies against a subunit of fibrinogen
US6727102B1 (en) 1997-06-20 2004-04-27 Leuven Research & Development Vzw Assays, antibodies, and standards for detection of oxidized and MDA-modified low density lipoproteins
US6309888B1 (en) * 1998-09-04 2001-10-30 Leuven Research & Development Vzw Detection and determination of the stages of coronary artery disease
IL134828A0 (en) * 2000-03-01 2001-05-20 Eship 4U Com Inc System for delivery and receipt of dispatches especially useful for e-commerce
US20050181451A1 (en) * 2004-02-12 2005-08-18 Bates Harold M. Detection of asymptomatic coronary artery disease using atherogenic proteins and acute phase reactants
EP1832654B1 (en) * 2004-12-28 2011-07-27 Sekisui Medical Co., Ltd. Anti-human soluble fibrin monoclonal antibody and immunological assay method using the antibody
CA2831572C (en) 2011-05-02 2019-11-26 Immunomedics, Inc. Ultrafiltration concentration of allotype selected antibodies for small-volume administration
EP2885002A4 (en) 2012-08-14 2016-04-20 Ibc Pharmaceuticals Inc BISPECIFIC ANTIBODIES REDIRECTED AGAINST T CELLS FOR THE TREATMENT OF DISEASES
AU2013360335B2 (en) 2012-12-13 2017-12-07 Immunomedics, Inc. Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity
CN110563258A (zh) * 2019-09-06 2019-12-13 广东石油化工学院 一种猪场废水厌氧产氢与达标排放处理方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU572125B2 (en) * 1983-03-17 1988-05-05 Mabco Limited Monoclonal antibodies with specificity for crosslinked fibrin and their diagnotic uses
US4722903A (en) * 1983-11-14 1988-02-02 New York Blood Center, Inc. Monoclonal antibodies specific to in vivo fragments derived from human fibrinogen, human fiberin I or human fibrin II
US4916070A (en) * 1986-04-14 1990-04-10 The General Hospital Corporation Fibrin-specific antibodies and method of screening for the antibodies
JP2635343B2 (ja) * 1986-04-14 1997-07-30 ザ・ジェネラル・ホスピタル・コーポレーション ヘテロ二官能性抗体および利用方法
AU7912887A (en) * 1986-08-25 1988-03-24 American Biogenetic Sciences, Inc. Monoclonal antibodies to fibrin
DE3701812A1 (de) * 1987-01-22 1988-08-04 Max Planck Gesellschaft Fibrinspezifischer antikoerper, verfahren zur seiner herstellung und seine verwendung
US5120834A (en) * 1988-06-13 1992-06-09 American Biogenetic Sciences, Inc. Fibrin-specific monoclonal antibody
SG50681A1 (en) * 1988-06-13 1998-07-20 American Biogenetic Sciences Method for the production of monoclonal antibodies utilizing a germfree animal
US5223410A (en) * 1988-06-13 1993-06-29 American Biogenetic Sciences, Inc. Method for production of antibodies utilizing an antigen-free animal
US5091512A (en) * 1988-06-13 1992-02-25 American Biogenetic Sciences, Inc. Fibrinogen-specific monoclonal antibody
US5206140A (en) 1988-06-24 1993-04-27 Research Corporation Technologies, Inc. Assay for soluble crosslinked fibrin polymers
CA2052283A1 (en) * 1990-09-27 1992-03-28 Edgar Haber Recombinant hybrid immunoglobulin molecules and method of use

Also Published As

Publication number Publication date
HUT76536A (en) 1997-09-29
LT4192B (en) 1997-07-25
NZ281481A (en) 1998-07-28
LV11784A (lv) 1997-06-20
MD1521G2 (ro) 2001-03-31
GEP20002257B (en) 2000-10-25
AU708897B2 (en) 1999-08-12
KR970701063A (ko) 1997-03-17
NO963497D0 (no) 1996-08-22
BG62476B1 (bg) 1999-12-30
US5487892A (en) 1996-01-30
CN1146157A (zh) 1997-03-26
FI963288A (fi) 1996-08-23
BG100863A (en) 1997-08-29
MX9603602A (es) 1997-05-31
NO963497L (no) 1996-10-16
RU2152801C2 (ru) 2000-07-20
PL316005A1 (en) 1996-12-23
FI963288A0 (fi) 1996-08-23
EP0749320A1 (en) 1996-12-27
AU1843495A (en) 1995-09-11
SK108496A3 (en) 1997-10-08
MD1521F2 (en) 2000-08-31
WO1995022986A1 (en) 1995-08-31
CA2183953A1 (en) 1995-08-31
BR9506949A (pt) 1997-09-23
LT96140A (en) 1997-03-25
JPH09509429A (ja) 1997-09-22
LV11784B (en) 1997-12-20
EP0749320A4 (en) 1997-06-18
CZ246496A3 (en) 1997-04-16
UA41984C2 (uk) 2001-10-15
TJ301B (en) 2001-08-06
MD960334A (en) 1997-09-30
HU9602337D0 (en) 1996-10-28

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