SG43682A1 - Pharmaceutical composition containing nanocapsules - Google Patents

Pharmaceutical composition containing nanocapsules

Info

Publication number
SG43682A1
SG43682A1 SG1995001958A SG1995001958A SG43682A1 SG 43682 A1 SG43682 A1 SG 43682A1 SG 1995001958 A SG1995001958 A SG 1995001958A SG 1995001958 A SG1995001958 A SG 1995001958A SG 43682 A1 SG43682 A1 SG 43682A1
Authority
SG
Singapore
Prior art keywords
nanocapsules
pharmaceutical composition
suspension
composition
composition containing
Prior art date
Application number
SG1995001958A
Other languages
English (en)
Inventor
Henry Vranckx
Martine Demoustier
Michel Deleers
Original Assignee
Ucb Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Sa filed Critical Ucb Sa
Publication of SG43682A1 publication Critical patent/SG43682A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/14—Polymerisation; cross-linking
    • B01J13/18—In situ polymerisation with all reactants being present in the same phase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y10T428/2985—Solid-walled microcapsule from synthetic polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SG1995001958A 1993-01-18 1994-01-05 Pharmaceutical composition containing nanocapsules SG43682A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939300875A GB9300875D0 (en) 1993-01-18 1993-01-18 Nanocapsule containing pharmaceutical compositions

Publications (1)

Publication Number Publication Date
SG43682A1 true SG43682A1 (en) 1997-11-14

Family

ID=10728864

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1995001958A SG43682A1 (en) 1993-01-18 1994-01-05 Pharmaceutical composition containing nanocapsules

Country Status (21)

Country Link
US (1) US5500224A (de)
EP (1) EP0608207B1 (de)
JP (1) JP3688731B2 (de)
KR (1) KR100311056B1 (de)
AT (1) ATE172111T1 (de)
AU (1) AU670840B2 (de)
CA (1) CA2113243C (de)
CY (1) CY2132B1 (de)
DE (1) DE69413857T2 (de)
DK (1) DK0608207T3 (de)
ES (1) ES2122217T3 (de)
FI (1) FI111441B (de)
GB (1) GB9300875D0 (de)
HU (1) HUT67213A (de)
NO (1) NO307445B1 (de)
NZ (1) NZ250673A (de)
PL (1) PL173254B1 (de)
RU (1) RU2145498C1 (de)
SG (1) SG43682A1 (de)
TW (1) TW336174B (de)
ZA (1) ZA94205B (de)

Families Citing this family (48)

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FR2721510B1 (fr) * 1994-06-22 1996-07-26 Rhone Poulenc Rorer Sa Nanoparticules filtrables dans des conditions stériles.
ES2154806T3 (es) * 1995-02-06 2001-04-16 Elan Pharma Int Ltd Formulaciones de compuestos como dispersiones de nanoparticulas en aceites o acidos grasos digeribles.
JP3759986B2 (ja) * 1995-12-07 2006-03-29 フロイント産業株式会社 シームレスカプセルおよびその製造方法
FR2766368B1 (fr) * 1997-07-24 2000-03-31 Univ Claude Bernard Lyon Procede de preparation de nanocapsules de type vesiculaire, utilisables notamment comme vecteurs colloidaux de principes actifs pharmaceutiques ou autres
US6761903B2 (en) 1999-06-30 2004-07-13 Lipocine, Inc. Clear oil-containing pharmaceutical compositions containing a therapeutic agent
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US20030236236A1 (en) * 1999-06-30 2003-12-25 Feng-Jing Chen Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
US6982281B1 (en) * 2000-11-17 2006-01-03 Lipocine Inc Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
US6458383B2 (en) 1999-08-17 2002-10-01 Lipocine, Inc. Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin
EP1267946A4 (de) * 2000-02-28 2008-07-02 Genesegues Inc Nanokapsel-einkapselungs-system und verfahren
FR2806005B1 (fr) * 2000-03-10 2002-06-14 Univ Claude Bernard Lyon Procede de preparation de particules colloidales sous forme de nanocapsules
US7153525B1 (en) 2000-03-22 2006-12-26 The University Of Kentucky Research Foundation Microemulsions as precursors to solid nanoparticles
CN1531436A (zh) * 2001-05-09 2004-09-22 (株)美大富历寿 用于增强粘膜吸收的两亲肝素衍生物制剂
WO2003024425A1 (en) * 2001-09-19 2003-03-27 Elan Pharma International, Ltd. Nanoparticulate insulin formulations
AU2002362039B2 (en) * 2001-12-03 2007-07-26 Soligenix, Inc Stabilized reverse micelle compositions and uses thereof
US20040038303A1 (en) * 2002-04-08 2004-02-26 Unger Gretchen M. Biologic modulations with nanoparticles
KR20050038005A (ko) 2002-07-18 2005-04-25 헬릭스 바이오파마 코포레이션 암세포 성장의 저해를 위한 우레아제의 사용
AU2003302226A1 (en) * 2002-09-24 2004-06-30 University Of Kentucky Research Foundation Nanoparticle-based vaccine delivery system containing adjuvant
WO2004084870A1 (en) * 2003-03-28 2004-10-07 Sigmoid Biotechnologies Limited Solid oral dosage form containing seamless microcapsules
US20060003002A1 (en) * 2003-11-03 2006-01-05 Lipocine, Inc. Pharmaceutical compositions with synchronized solubilizer release
PL1811979T3 (pl) * 2004-09-27 2009-04-30 Sigmoid Pharma Ltd Mikrokapsułki zawierające metyloksantynę i kortykosteroid
FR2899797A1 (fr) * 2006-04-13 2007-10-19 Oreal Emulsion eau dans l'huile pour le traitement des fibres keratiniques comprenant un monomere cyanoacrylate et de l'ammoniaque
FR2899800B1 (fr) * 2006-04-13 2008-10-10 Oreal Emulsion eau dans l'huile pour le traitement des fibres keratiniques comprenant un monomere cyanoacrylate
JP2010523554A (ja) 2007-04-04 2010-07-15 シグモイド・ファーマ・リミテッド タクロリムスの医薬組成物
CA2942083C (en) * 2007-04-26 2019-01-29 Sigmoid Pharma Limited Manufacture of multiple minicapsules
CA2685591A1 (en) * 2007-05-01 2008-11-06 Sigmoid Pharma Limited Pharmaceutical nimodipine compositions
WO2009114365A2 (en) * 2008-03-13 2009-09-17 Mallinckrodt Inc. Multi-function, foot-activated controller for imaging system
US20110059142A1 (en) * 2008-05-06 2011-03-10 Irene Papanicolaou Encapsulation of biologically active agents
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
SI2432455T1 (sl) 2009-05-18 2015-04-30 Sigmoid Pharma Limited Sestava, obsegajoäśa oljne kapljice
WO2011018504A2 (en) 2009-08-12 2011-02-17 Sigmoid Pharma Limited Immunomodulatory compositions comprising a polymer matrix and an oil phase
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
RU2566069C2 (ru) * 2013-05-31 2015-10-20 Общество с ограниченной ответственностью "Изварино Фарма" Система доставки вещества белковой природы в виде наночастиц и способ ее получения
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
US20170189344A1 (en) * 2014-05-30 2017-07-06 AbbVie Deutschland GmbH & Co. KG Highly drug-loaded poly(alkyl 2-cyanoacrylate) nanocapsules
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
AU2015311857A1 (en) 2014-09-03 2017-03-23 Genesegues, Inc. Therapeutic nanoparticles and related compositions, methods and systems
KR20170102223A (ko) 2014-11-07 2017-09-08 시그모이드 파마 리미티드 사이클로스포린을 포함하는 조성물
CN118873680A (zh) 2015-01-23 2024-11-01 赫利克斯生物药品公司 用于治疗目的的抗体-脲酶缀合物
RU2590651C1 (ru) * 2015-03-30 2016-07-10 Александр Александрович Кролевец Способ получения нанокапсул рибофлавина в геллановой камеди
CA3078723A1 (en) 2016-11-28 2018-05-31 Nachiappan Chidambaram Oral testosterone undecanoate therapy
WO2023089240A1 (en) * 2021-11-19 2023-05-25 Nanoform Finland Oyj A composition comprising nanosized active pharmaceutical ingredient

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FR2515960A1 (fr) * 1981-11-06 1983-05-13 Alkhouri Fallouh Nazir Nanocapsules ou nanoparticules biodegradables contenant une substance biologiquement active, leur preparation et leur application
JPS6061521A (ja) * 1983-09-16 1985-04-09 Kyowa Hakko Kogyo Co Ltd マイクロカプセル化製剤
DE3341001A1 (de) * 1983-11-12 1985-05-23 Krause, Hans Jürgen Nanopartikel aus bioabbaubarem, synthetischem material, verfahren zu deren herstellung und ihre anwendung
FR2659554B1 (fr) * 1990-03-16 1994-09-30 Oreal Composition pour le traitement cosmetique et/ou pharmaceutique des couches superieures de l'epiderme par application topique sur la peau et procede de preparation correspondant.

Also Published As

Publication number Publication date
FI111441B (fi) 2003-07-31
ES2122217T3 (es) 1998-12-16
DK0608207T3 (da) 1999-06-23
DE69413857D1 (de) 1998-11-19
AU5309794A (en) 1994-07-21
CA2113243A1 (en) 1994-07-19
HU9400107D0 (en) 1994-05-30
NZ250673A (en) 1994-11-25
FI940115A (fi) 1994-07-19
PL301841A1 (en) 1994-07-25
ATE172111T1 (de) 1998-10-15
KR940018086A (ko) 1994-08-16
AU670840B2 (en) 1996-08-01
KR100311056B1 (ko) 2002-03-21
NO940111D0 (no) 1994-01-12
TW336174B (en) 1998-07-11
EP0608207B1 (de) 1998-10-14
FI940115A0 (fi) 1994-01-11
RU94002474A (ru) 1996-11-10
US5500224A (en) 1996-03-19
DE69413857T2 (de) 1999-04-15
NO940111L (no) 1994-07-19
CA2113243C (en) 2008-08-05
RU2145498C1 (ru) 2000-02-20
ZA94205B (en) 1994-08-22
EP0608207A1 (de) 1994-07-27
GB9300875D0 (en) 1993-03-10
JP3688731B2 (ja) 2005-08-31
PL173254B1 (pl) 1998-02-27
JPH06256172A (ja) 1994-09-13
NO307445B1 (no) 2000-04-10
HUT67213A (en) 1995-03-28
CY2132B1 (en) 2002-06-21

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