SG193380A1 - 6-substituted estradiol derivatives for use in remyelination of nerve axons - Google Patents
6-substituted estradiol derivatives for use in remyelination of nerve axons Download PDFInfo
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- SG193380A1 SG193380A1 SG2013067962A SG2013067962A SG193380A1 SG 193380 A1 SG193380 A1 SG 193380A1 SG 2013067962 A SG2013067962 A SG 2013067962A SG 2013067962 A SG2013067962 A SG 2013067962A SG 193380 A1 SG193380 A1 SG 193380A1
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- Prior art keywords
- methyl
- cyclopenta
- decahydro
- phenanthrene
- diol
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Landscapes
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
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| US201161454873P | 2011-03-21 | 2011-03-21 | |
| PCT/US2012/029973 WO2012129324A2 (en) | 2011-03-21 | 2012-03-21 | 6-substituted estradiol derivatives for use in remyelination of nerve axons |
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| US9315540B2 (en) | 2012-10-22 | 2016-04-19 | Intas Pharmaceuticals Ltd. | Process for the preparation of fulvestrant |
| AU2015231172A1 (en) * | 2014-03-19 | 2016-09-08 | Endece Llc | 6-substituted estradiol derivatives for the treatment of Alzheimer's Disease |
| US20210024568A1 (en) * | 2019-07-23 | 2021-01-28 | Endece Llc | Methods for modulation of lipoprotein lipase and apolipoprotein c2 expression and/or activity in the treatment of peripheral and central nervous system tissue disease states |
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| US4136160A (en) * | 1977-08-17 | 1979-01-23 | Cohen Steven R | Specific assay for active demyelinization |
| JPH0193529A (ja) * | 1987-10-05 | 1989-04-12 | Mect Corp | シアロシルコレステロールの脱髄性疾患治療剤 |
| JPH01193529A (ja) | 1988-01-27 | 1989-08-03 | Yoshitsugu Takano | 液体循環装置 |
| BRPI0616639A2 (pt) * | 2005-09-30 | 2011-06-28 | Endece Llc | compostos de exemestano de (s)-6-metiloxaalquila e métodos de uso relacionados |
| US8168621B2 (en) * | 2005-09-30 | 2012-05-01 | Endece, Llc | 6-substituted estradiol derivatives and methods of use |
| US10174070B2 (en) * | 2005-09-30 | 2019-01-08 | Endece Llc | 6-substituted estradiol derivatives and methods of use |
| WO2008067450A2 (en) * | 2006-11-30 | 2008-06-05 | Endece, Llc | 6-alkoxyalkyl estradiol derivatives and methods of use |
| BR112013005843A2 (pt) | 2010-09-14 | 2019-12-10 | Endece Llc | derivativos de er-beta 6-substituído por desmetil-estradiol |
| MX354409B (es) * | 2011-03-21 | 2018-03-05 | Endece Llc | Derivados de estradiol sustituidos en 6 para uso en remielinización de axones nerviosos. |
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Also Published As
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| CA2830515C (en) | 2015-09-15 |
| JP2014508807A (ja) | 2014-04-10 |
| EP2688570A4 (en) | 2014-09-10 |
| AU2012230974B2 (en) | 2016-05-12 |
| AU2012230974A1 (en) | 2013-09-26 |
| US20160279144A1 (en) | 2016-09-29 |
| CN106420767A (zh) | 2017-02-22 |
| US9636348B2 (en) | 2017-05-02 |
| US9364486B2 (en) | 2016-06-14 |
| BR112013024168A2 (pt) | 2017-07-11 |
| KR102080151B1 (ko) | 2020-02-21 |
| DK2688570T3 (en) | 2015-12-21 |
| MX354409B (es) | 2018-03-05 |
| MX2013010650A (es) | 2013-10-07 |
| JP6174563B2 (ja) | 2017-08-02 |
| EP2688570B1 (en) | 2015-11-18 |
| CN103501790B (zh) | 2016-08-17 |
| WO2012129324A2 (en) | 2012-09-27 |
| KR20140074253A (ko) | 2014-06-17 |
| ES2561536T3 (es) | 2016-02-26 |
| US20120245131A1 (en) | 2012-09-27 |
| CN103501790A (zh) | 2014-01-08 |
| WO2012129324A9 (en) | 2012-11-15 |
| CA2830515A1 (en) | 2012-09-27 |
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