AU2012230974B2 - 6-substituted estradiol derivatives for use in remyelination of nerve axons - Google Patents
6-substituted estradiol derivatives for use in remyelination of nerve axons Download PDFInfo
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- AU2012230974B2 AU2012230974B2 AU2012230974A AU2012230974A AU2012230974B2 AU 2012230974 B2 AU2012230974 B2 AU 2012230974B2 AU 2012230974 A AU2012230974 A AU 2012230974A AU 2012230974 A AU2012230974 A AU 2012230974A AU 2012230974 B2 AU2012230974 B2 AU 2012230974B2
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- Prior art keywords
- methyl
- cyclopenta
- decahydro
- phenanthrene
- diol
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Landscapes
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| US201161454873P | 2011-03-21 | 2011-03-21 | |
| US61/454,873 | 2011-03-21 | ||
| PCT/US2012/029973 WO2012129324A2 (en) | 2011-03-21 | 2012-03-21 | 6-substituted estradiol derivatives for use in remyelination of nerve axons |
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| AU2012230974A1 AU2012230974A1 (en) | 2013-09-26 |
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| WO2014064712A2 (en) * | 2012-10-22 | 2014-05-01 | Intas Pharmaceuticals Limited | An improved process for the preparation of fulvestrant |
| US20150265630A1 (en) * | 2014-03-19 | 2015-09-24 | Endece Llc | 6-Substituted Estradiol Derivatives for the Treatment of Alzheimer's Disease |
| US20210024568A1 (en) * | 2019-07-23 | 2021-01-28 | Endece Llc | Methods for modulation of lipoprotein lipase and apolipoprotein c2 expression and/or activity in the treatment of peripheral and central nervous system tissue disease states |
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| US20100130463A1 (en) * | 2005-09-30 | 2010-05-27 | Yarger James G | 6-substituted estradiol derivatives and methods of use |
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| US4136160A (en) * | 1977-08-17 | 1979-01-23 | Cohen Steven R | Specific assay for active demyelinization |
| JPH0193529A (ja) * | 1987-10-05 | 1989-04-12 | Mect Corp | シアロシルコレステロールの脱髄性疾患治療剤 |
| JPH01193529A (ja) | 1988-01-27 | 1989-08-03 | Yoshitsugu Takano | 液体循環装置 |
| KR101484134B1 (ko) * | 2005-09-30 | 2015-01-21 | 엔디씨, 엘엘씨 | (ｓ)-６-메틸옥사알킬 엑스메스탄 화합물 및 관련 사용방법 |
| US8168621B2 (en) * | 2005-09-30 | 2012-05-01 | Endece, Llc | 6-substituted estradiol derivatives and methods of use |
| ES2604079T3 (es) * | 2006-11-30 | 2017-03-02 | Endece, Llc | Derivados de 6-alcoxialquil estradiol y métodos de uso |
| AU2011302065B2 (en) | 2010-09-14 | 2016-12-01 | Endece, Llc | 6-substituted demethyl-estradiol derivatives as ER-beta agonists |
| DK2688570T3 (en) * | 2011-03-21 | 2015-12-21 | Endece Llc | 6-substituted estradiol for use in the remyelination of nerve axons |
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| US20100130463A1 (en) * | 2005-09-30 | 2010-05-27 | Yarger James G | 6-substituted estradiol derivatives and methods of use |
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| EP2688570A4 (en) | 2014-09-10 |
| US20160279144A1 (en) | 2016-09-29 |
| WO2012129324A9 (en) | 2012-11-15 |
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| CA2830515C (en) | 2015-09-15 |
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| AU2012230974A1 (en) | 2013-09-26 |
| KR102080151B1 (ko) | 2020-02-21 |
| ES2561536T3 (es) | 2016-02-26 |
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| US9364486B2 (en) | 2016-06-14 |
| CN103501790A (zh) | 2014-01-08 |
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| CN103501790B (zh) | 2016-08-17 |
| MX354409B (es) | 2018-03-05 |
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