SG192124A1 - Compositions and methods for cell transplantation - Google Patents
Compositions and methods for cell transplantation Download PDFInfo
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- SG192124A1 SG192124A1 SG2013056510A SG2013056510A SG192124A1 SG 192124 A1 SG192124 A1 SG 192124A1 SG 2013056510 A SG2013056510 A SG 2013056510A SG 2013056510 A SG2013056510 A SG 2013056510A SG 192124 A1 SG192124 A1 SG 192124A1
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- cells
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- cell
- liver
- thrombin inhibitor
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- 210000001685 thyroid gland Anatomy 0.000 description 1
- 210000002303 tibia Anatomy 0.000 description 1
- 239000003104 tissue culture media Substances 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 230000014723 transformation of host cell by virus Effects 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 238000003146 transient transfection Methods 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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- 208000030954 urea cycle disease Diseases 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 210000005048 vimentin Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 210000001325 yolk sac Anatomy 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/407—Liver; Hepatocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
- A61K38/58—Protease inhibitors from animals; from humans from leeches, e.g. hirudin, eglin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11152119 | 2011-01-25 | ||
| PCT/EP2012/051157 WO2012101181A1 (en) | 2011-01-25 | 2012-01-25 | Compositions and methods for cell transplantation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG192124A1 true SG192124A1 (en) | 2013-08-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013056510A SG192124A1 (en) | 2011-01-25 | 2012-01-25 | Compositions and methods for cell transplantation |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US20130302291A1 (enExample) |
| EP (1) | EP2667878B1 (enExample) |
| JP (1) | JP6012629B2 (enExample) |
| CN (1) | CN103402527B (enExample) |
| CA (1) | CA2825252C (enExample) |
| DK (1) | DK2667878T3 (enExample) |
| ES (1) | ES2573522T3 (enExample) |
| IL (1) | IL227529A0 (enExample) |
| PL (1) | PL2667878T3 (enExample) |
| PT (1) | PT2667878E (enExample) |
| SG (1) | SG192124A1 (enExample) |
| WO (1) | WO2012101181A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2573522T3 (es) | 2011-01-25 | 2016-06-08 | Université Catholique de Louvain | Composiciones y métodos para el trasplante celular |
| ES2726802T3 (es) | 2012-01-25 | 2019-10-09 | Univ Catholique Louvain | Composiciones y métodos para el trasplante celular |
| EP2943206A4 (en) * | 2013-01-12 | 2017-01-04 | Cesca Therapeutics Inc. | Rapid infusion of autologous bone marrow derived stem cells |
| SG10201906304TA (en) * | 2013-03-15 | 2019-08-27 | Miromatrix Medical Inc | Use of perfusion decellularized liver for islet cell recellularization |
| JP6474394B2 (ja) | 2013-07-05 | 2019-02-27 | ユニベルシテ カトリック ドゥ ルーベン | ヒト成体肝臓幹細胞由来の馴化培地および肝臓障害の治療におけるその使用 |
| BR102013033827B1 (pt) * | 2013-12-27 | 2021-09-08 | Regenera - Medicina Veterinária Avançada Ltda. | Concentrado multipotente e imunocompatível de células-tronco e biofármaco e forma de dosagem que o compreendem |
| WO2016198578A1 (en) * | 2015-06-11 | 2016-12-15 | Universiteit Maastricht | Method for preventing transplant failure in a host. |
| CN106995796A (zh) * | 2016-01-26 | 2017-08-01 | 李建业 | 基于细胞因子的细胞处理方法、试剂盒及冻干粉 |
| EP3591037A4 (en) * | 2017-03-03 | 2020-11-11 | Rohto Pharmaceutical Co., Ltd. | MESENCHYMATIC STEM CELL AND THERAPEUTIC AGENT AGAINST LIVER DISEASES |
| KR20200028391A (ko) | 2017-06-12 | 2020-03-16 | 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 | 세포 생착용 패치 이식편 조성물 |
| JP7264589B2 (ja) * | 2017-12-25 | 2023-04-25 | 株式会社 資生堂 | トロンビンの抑制作用を指標とした皮膚状態改善剤のスクリーニング方法、及びトロンビン作用阻害剤を含む皮膚状態改善剤 |
| WO2019241499A1 (en) | 2018-06-13 | 2019-12-19 | Miromatrix Medical Inc. | Fistula filler and deployment system |
| CN113677790B (zh) * | 2019-03-26 | 2024-05-24 | 普罗米瑟拉疗法公司 | 用于治疗慢加急性肝衰竭的成体肝祖细胞 |
| CN112608890B (zh) * | 2020-12-17 | 2024-08-20 | 山东佰鸿干细胞生物技术有限公司 | 一种防止间充质干细胞粘连的培养方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9010552D0 (en) | 1990-05-10 | 1990-07-04 | Erba Carlo Spa | Method for the recombinant production of hirudins and novel hirudins |
| US5811094A (en) | 1990-11-16 | 1998-09-22 | Osiris Therapeutics, Inc. | Connective tissue regeneration using human mesenchymal stem cell preparations |
| US5837539A (en) | 1990-11-16 | 1998-11-17 | Osiris Therapeutics, Inc. | Monoclonal antibodies for human mesenchymal stem cells |
| US5486359A (en) | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US5736396A (en) | 1995-01-24 | 1998-04-07 | Case Western Reserve University | Lineage-directed induction of human mesenchymal stem cell differentiation |
| US5827740A (en) | 1996-07-30 | 1998-10-27 | Osiris Therapeutics, Inc. | Adipogenic differentiation of human mesenchymal stem cells |
| GB0014136D0 (en) | 2000-06-10 | 2000-08-02 | Astrazeneca Ab | Combination therapy |
| DE10202982A1 (de) | 2002-01-26 | 2003-07-31 | Augustinus Bader | Verfahren und Vorrichtung zum Einbringen von lebenden Zellen in eine biologische Körperflüssigkeit |
| US20060222640A1 (en) * | 2005-03-29 | 2006-10-05 | Boehringer Ingelheim International Gmbh | New pharmaceutical compositions for treatment of thrombosis |
| WO2006126219A1 (en) | 2005-05-26 | 2006-11-30 | Fresenius Medical Care Deutschland G.M.B.H. | Liver progenitor cells |
| JP2009508650A (ja) * | 2005-09-21 | 2009-03-05 | ダスク テクノロジーズ， エルエルシー | 臓器および組織機能のための方法および組成 |
| CA2634510C (en) * | 2005-12-21 | 2018-01-09 | Universite Catholique De Louvain | Isolated liver stem cells |
| ES2573522T3 (es) | 2011-01-25 | 2016-06-08 | Université Catholique de Louvain | Composiciones y métodos para el trasplante celular |
| ES2726802T3 (es) | 2012-01-25 | 2019-10-09 | Univ Catholique Louvain | Composiciones y métodos para el trasplante celular |
-
2012
- 2012-01-25 ES ES12704242.2T patent/ES2573522T3/es active Active
- 2012-01-25 PT PT127042422T patent/PT2667878E/pt unknown
- 2012-01-25 DK DK12704242.2T patent/DK2667878T3/en active
- 2012-01-25 JP JP2013549850A patent/JP6012629B2/ja not_active Expired - Fee Related
- 2012-01-25 WO PCT/EP2012/051157 patent/WO2012101181A1/en not_active Ceased
- 2012-01-25 PL PL12704242.2T patent/PL2667878T3/pl unknown
- 2012-01-25 US US13/981,720 patent/US20130302291A1/en not_active Abandoned
- 2012-01-25 EP EP12704242.2A patent/EP2667878B1/en not_active Not-in-force
- 2012-01-25 CA CA2825252A patent/CA2825252C/en not_active Expired - Fee Related
- 2012-01-25 CN CN201280011169.6A patent/CN103402527B/zh not_active Expired - Fee Related
- 2012-01-25 SG SG2013056510A patent/SG192124A1/en unknown
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2013
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2016
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2017
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Also Published As
| Publication number | Publication date |
|---|---|
| IL227529A0 (en) | 2013-09-30 |
| CA2825252C (en) | 2018-10-16 |
| JP2014508138A (ja) | 2014-04-03 |
| EP2667878B1 (en) | 2016-03-30 |
| EP2667878A1 (en) | 2013-12-04 |
| CN103402527B (zh) | 2016-04-20 |
| US10039789B2 (en) | 2018-08-07 |
| WO2012101181A1 (en) | 2012-08-02 |
| US10478459B2 (en) | 2019-11-19 |
| PL2667878T3 (pl) | 2016-10-31 |
| PT2667878E (pt) | 2016-06-03 |
| US20130302291A1 (en) | 2013-11-14 |
| CA2825252A1 (en) | 2012-08-02 |
| US20170354723A1 (en) | 2017-12-14 |
| US20170042940A1 (en) | 2017-02-16 |
| JP6012629B2 (ja) | 2016-10-25 |
| DK2667878T3 (en) | 2016-06-27 |
| CN103402527A (zh) | 2013-11-20 |
| ES2573522T3 (es) | 2016-06-08 |
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