SG178744A1 - Use of semaphorin 6a for promoting myelination and oligodendrocyte differentiation - Google Patents

Use of semaphorin 6a for promoting myelination and oligodendrocyte differentiation Download PDF

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Publication number
SG178744A1
SG178744A1 SG2012007456A SG2012007456A SG178744A1 SG 178744 A1 SG178744 A1 SG 178744A1 SG 2012007456 A SG2012007456 A SG 2012007456A SG 2012007456 A SG2012007456 A SG 2012007456A SG 178744 A1 SG178744 A1 SG 178744A1
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Singapore
Prior art keywords
seq
polypeptide
sema6a
mammal
disease
Prior art date
Application number
SG2012007456A
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English (en)
Inventor
Alain Chedotal
Sha Mi
Frederic Bernard
Original Assignee
Biogen Idec Inc
Centre Nat Rech Scient
Univ Pierre And Marie Curie
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Publication date
Application filed by Biogen Idec Inc, Centre Nat Rech Scient, Univ Pierre And Marie Curie filed Critical Biogen Idec Inc
Publication of SG178744A1 publication Critical patent/SG178744A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276Knock-out vertebrates
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
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    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
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    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
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    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0622Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/072Animals genetically altered by homologous recombination maintaining or altering function, i.e. knock in
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
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    • C12N2502/08Coculture with; Conditioned medium produced by cells of the nervous system
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    • C12N2510/00Genetically modified cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
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  • Environmental Sciences (AREA)
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  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
SG2012007456A 2007-02-02 2008-02-04 Use of semaphorin 6a for promoting myelination and oligodendrocyte differentiation SG178744A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89899207P 2007-02-02 2007-02-02

Publications (1)

Publication Number Publication Date
SG178744A1 true SG178744A1 (en) 2012-03-29

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US (1) US9107884B2 (enExample)
EP (1) EP2114433B1 (enExample)
JP (1) JP5492567B2 (enExample)
KR (1) KR20090123873A (enExample)
CN (1) CN101631559A (enExample)
AU (1) AU2008214337B2 (enExample)
BR (1) BRPI0806849A2 (enExample)
CA (1) CA2677228C (enExample)
EA (1) EA017403B1 (enExample)
GE (1) GEP20135853B (enExample)
IL (1) IL200123A (enExample)
MX (1) MX2009008178A (enExample)
NZ (1) NZ578816A (enExample)
SG (1) SG178744A1 (enExample)
UA (1) UA99452C2 (enExample)
WO (1) WO2008097503A2 (enExample)
ZA (1) ZA200905379B (enExample)

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DK2820042T3 (da) * 2012-02-29 2019-10-28 Baxalta GmbH Igg-stimuleret remyelinisering af perifere nerver
SG11201703148TA (en) 2014-11-05 2017-05-30 Voyager Therapeutics Inc Aadc polynucleotides for the treatment of parkinson's disease
DK3218386T3 (da) 2014-11-14 2021-06-07 Voyager Therapeutics Inc Modulatorisk polynukleotid
CA3193811A1 (en) 2014-11-14 2016-05-19 Voyager Therapeutics, Inc. Compositions and methods of treating amyotrophic lateral sclerosis (als)
RU2722832C2 (ru) * 2015-02-23 2020-06-04 Сигалл Терапьютикс Сас Неприродные семафорины класса 3 и их медицинское применение
ES2969187T3 (es) * 2015-06-29 2024-05-16 Univ British Columbia Tratamientos, métodos y usos de la proteína de fusión B1SP
AU2017267665C1 (en) 2016-05-18 2023-10-05 Voyager Therapeutics, Inc. Modulatory polynucleotides
JP7109040B2 (ja) * 2016-07-25 2022-07-29 国立大学法人金沢大学 線維化抑制剤
EP3618839A4 (en) 2017-05-05 2021-06-09 Voyager Therapeutics, Inc. Compositions and methods of treating amyotrophic lateral sclerosis (als)
JOP20190269A1 (ar) 2017-06-15 2019-11-20 Voyager Therapeutics Inc بولي نوكليوتيدات aadc لعلاج مرض باركنسون
US12319929B2 (en) 2018-05-15 2025-06-03 Voyager Therapeutics, Inc. Compositions and methods for the treatment of Parkinson's disease
CN109536506B (zh) * 2018-12-10 2022-03-22 潍坊科技学院 一种调控日本沼虾生长发育的类胰岛素受体基因及其应用
KR20250075466A (ko) * 2023-11-15 2025-05-28 주식회사 카인사이언스 탈수초 질환 치료용 펩타이드 및 이의 용도

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Publication number Publication date
CA2677228C (en) 2015-12-08
WO2008097503A3 (en) 2008-12-24
KR20090123873A (ko) 2009-12-02
NZ578816A (en) 2012-06-29
IL200123A0 (en) 2010-04-15
AU2008214337B2 (en) 2012-07-05
JP2010518007A (ja) 2010-05-27
EP2114433B1 (en) 2014-04-09
EA200901067A1 (ru) 2010-02-26
BRPI0806849A2 (pt) 2015-06-23
CN101631559A (zh) 2010-01-20
US20100189713A1 (en) 2010-07-29
AU2008214337A1 (en) 2008-08-14
EA017403B1 (ru) 2012-12-28
WO2008097503A2 (en) 2008-08-14
GEP20135853B (en) 2013-06-25
CA2677228A1 (en) 2008-08-14
US9107884B2 (en) 2015-08-18
IL200123A (en) 2013-05-30
EP2114433A2 (en) 2009-11-11
ZA200905379B (en) 2014-01-29
MX2009008178A (es) 2009-10-26
WO2008097503A8 (en) 2009-11-05
UA99452C2 (ru) 2012-08-27
JP5492567B2 (ja) 2014-05-14

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