UA99452C2 - Способ стимулирования миелинизации и дифференцирования олигодендроцитов путем применения семафорина 6a - Google Patents
Способ стимулирования миелинизации и дифференцирования олигодендроцитов путем применения семафорина 6aInfo
- Publication number
- UA99452C2 UA99452C2 UAA200908176A UAA200908176A UA99452C2 UA 99452 C2 UA99452 C2 UA 99452C2 UA A200908176 A UAA200908176 A UA A200908176A UA A200908176 A UAA200908176 A UA A200908176A UA 99452 C2 UA99452 C2 UA 99452C2
- Authority
- UA
- Ukraine
- Prior art keywords
- semaphorin
- oligodendrocyte differentiation
- promoting myelination
- demyelination
- myelination
- Prior art date
Links
- 102100032795 Semaphorin-6A Human genes 0.000 title 1
- 101710199479 Semaphorin-6A Proteins 0.000 title 1
- 230000004069 differentiation Effects 0.000 title 1
- 230000023105 myelination Effects 0.000 title 1
- 210000004248 oligodendroglia Anatomy 0.000 title 1
- 230000001737 promoting effect Effects 0.000 title 1
- 208000016192 Demyelinating disease Diseases 0.000 abstract 2
- 206010012305 Demyelination Diseases 0.000 abstract 2
- 230000006378 damage Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- Health & Medical Sciences (AREA)
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- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
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- Zoology (AREA)
- Medicinal Chemistry (AREA)
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- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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Abstract
Изобретение относится к способам лечения заболеваний, расстройств или повреждений, при которых наблюдается демиелинизация и дисмиелинизация, в том числе рассеянного склероза, путем применения полипептида Sema6A.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89899207P | 2007-02-02 | 2007-02-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
UA99452C2 true UA99452C2 (ru) | 2012-08-27 |
Family
ID=39682299
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200908176A UA99452C2 (ru) | 2007-02-02 | 2008-02-04 | Способ стимулирования миелинизации и дифференцирования олигодендроцитов путем применения семафорина 6a |
Country Status (17)
Country | Link |
---|---|
US (1) | US9107884B2 (ru) |
EP (1) | EP2114433B1 (ru) |
JP (1) | JP5492567B2 (ru) |
KR (1) | KR20090123873A (ru) |
CN (1) | CN101631559A (ru) |
AU (1) | AU2008214337B2 (ru) |
BR (1) | BRPI0806849A2 (ru) |
CA (1) | CA2677228C (ru) |
EA (1) | EA017403B1 (ru) |
GE (1) | GEP20135853B (ru) |
IL (1) | IL200123A (ru) |
MX (1) | MX2009008178A (ru) |
NZ (1) | NZ578816A (ru) |
SG (1) | SG178744A1 (ru) |
UA (1) | UA99452C2 (ru) |
WO (1) | WO2008097503A2 (ru) |
ZA (1) | ZA200905379B (ru) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011066284A1 (en) * | 2009-11-25 | 2011-06-03 | The University Of North Carolina At Chapel Hill | Methods and compositions for the treatment of immune disorders |
CN110343171A (zh) * | 2012-02-29 | 2019-10-18 | 百深公司 | 周围神经的IgG刺激髓鞘再生 |
BR112017009497A2 (pt) | 2014-11-05 | 2018-02-06 | Voyager Therapeutics, Inc. | polinucleotídeos de aadc para o tratamento da doença de parkinson |
ES2878451T3 (es) | 2014-11-14 | 2021-11-18 | Voyager Therapeutics Inc | Polinucleótidos moduladores |
US10597660B2 (en) | 2014-11-14 | 2020-03-24 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (ALS) |
KR20170138410A (ko) * | 2015-02-23 | 2017-12-15 | 시걸 테라퓨틱스 에스에이에스 | 비-천연 세마포린 3 및 이의 의학적 용도 |
WO2017000059A1 (en) * | 2015-06-29 | 2017-01-05 | The University Of British Columbia | B1sp fusion protein therapeutics, methods, and uses |
KR20240056729A (ko) | 2016-05-18 | 2024-04-30 | 보이저 테라퓨틱스, 인크. | 조절성 폴리뉴클레오티드 |
JP7109040B2 (ja) * | 2016-07-25 | 2022-07-29 | 国立大学法人金沢大学 | 線維化抑制剤 |
CA3061652A1 (en) | 2017-05-05 | 2018-11-08 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (als) |
JOP20190269A1 (ar) | 2017-06-15 | 2019-11-20 | Voyager Therapeutics Inc | بولي نوكليوتيدات aadc لعلاج مرض باركنسون |
CN109536506B (zh) * | 2018-12-10 | 2022-03-22 | 潍坊科技学院 | 一种调控日本沼虾生长发育的类胰岛素受体基因及其应用 |
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2008
- 2008-02-04 GE GEAP200811447A patent/GEP20135853B/en unknown
- 2008-02-04 UA UAA200908176A patent/UA99452C2/ru unknown
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- 2008-02-04 WO PCT/US2008/001444 patent/WO2008097503A2/en active Application Filing
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- 2008-02-04 JP JP2009548329A patent/JP5492567B2/ja active Active
- 2008-02-04 CN CN200880003680A patent/CN101631559A/zh not_active Withdrawn
- 2008-02-04 EA EA200901067A patent/EA017403B1/ru not_active IP Right Cessation
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- 2008-02-04 EP EP08713389.8A patent/EP2114433B1/en active Active
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- 2008-02-04 US US12/525,514 patent/US9107884B2/en active Active
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2009
- 2009-07-28 IL IL200123A patent/IL200123A/en active IP Right Grant
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Also Published As
Publication number | Publication date |
---|---|
EP2114433B1 (en) | 2014-04-09 |
CN101631559A (zh) | 2010-01-20 |
US20100189713A1 (en) | 2010-07-29 |
GEP20135853B (en) | 2013-06-25 |
SG178744A1 (en) | 2012-03-29 |
IL200123A (en) | 2013-05-30 |
JP5492567B2 (ja) | 2014-05-14 |
AU2008214337B2 (en) | 2012-07-05 |
EA017403B1 (ru) | 2012-12-28 |
CA2677228A1 (en) | 2008-08-14 |
IL200123A0 (en) | 2010-04-15 |
WO2008097503A2 (en) | 2008-08-14 |
NZ578816A (en) | 2012-06-29 |
EA200901067A1 (ru) | 2010-02-26 |
WO2008097503A3 (en) | 2008-12-24 |
EP2114433A2 (en) | 2009-11-11 |
CA2677228C (en) | 2015-12-08 |
JP2010518007A (ja) | 2010-05-27 |
KR20090123873A (ko) | 2009-12-02 |
AU2008214337A1 (en) | 2008-08-14 |
WO2008097503A8 (en) | 2009-11-05 |
MX2009008178A (es) | 2009-10-26 |
BRPI0806849A2 (pt) | 2015-06-23 |
US9107884B2 (en) | 2015-08-18 |
ZA200905379B (en) | 2014-01-29 |
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