SG172474A1 - Method for treatment of indwelling catheter occlusion using fibrinolytic metalloproteinases - Google Patents

Method for treatment of indwelling catheter occlusion using fibrinolytic metalloproteinases Download PDF

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Publication number
SG172474A1
SG172474A1 SG2006088561A SG2006088561A SG172474A1 SG 172474 A1 SG172474 A1 SG 172474A1 SG 2006088561 A SG2006088561 A SG 2006088561A SG 2006088561 A SG2006088561 A SG 2006088561A SG 172474 A1 SG172474 A1 SG 172474A1
Authority
SG
Singapore
Prior art keywords
access device
vascular
fibrinolytic
catheter
nat
Prior art date
Application number
SG2006088561A
Other languages
English (en)
Inventor
Christopher F Toombs
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of SG172474A1 publication Critical patent/SG172474A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
SG2006088561A 1999-12-17 2003-06-23 Method for treatment of indwelling catheter occlusion using fibrinolytic metalloproteinases SG172474A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/466,276 US6455269B1 (en) 1999-12-17 1999-12-17 Method for localized administration of fibrinolytic metalloproteinases

Publications (1)

Publication Number Publication Date
SG172474A1 true SG172474A1 (en) 2011-07-28

Family

ID=23851165

Family Applications (1)

Application Number Title Priority Date Filing Date
SG2006088561A SG172474A1 (en) 1999-12-17 2003-06-23 Method for treatment of indwelling catheter occlusion using fibrinolytic metalloproteinases

Country Status (14)

Country Link
US (1) US6455269B1 (enExample)
EP (2) EP1239873B1 (enExample)
JP (1) JP2003517020A (enExample)
AT (1) ATE298585T1 (enExample)
AU (1) AU784252B2 (enExample)
CA (1) CA2394613A1 (enExample)
DE (1) DE60021111T2 (enExample)
DK (1) DK1239873T3 (enExample)
ES (1) ES2242655T3 (enExample)
HK (1) HK1050845B (enExample)
MX (1) MXPA02006024A (enExample)
PT (1) PT1239873E (enExample)
SG (1) SG172474A1 (enExample)
WO (1) WO2001043765A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440414B1 (en) * 1999-10-01 2002-08-27 Amgen Inc. Pharmaceutical compositions of fibrinolytic agent
US6261820B1 (en) * 1999-10-01 2001-07-17 Amgen Inc. Fibronolytically active polypeptide
US6455269B1 (en) * 1999-12-17 2002-09-24 Amgen, Inc. Method for localized administration of fibrinolytic metalloproteinases
US7033776B2 (en) * 1999-12-17 2006-04-25 Amgen Inc. Method for treatment of indwelling catheter occlusion using fibrinolytic metalloproteinases
US20090254062A1 (en) * 2008-04-03 2009-10-08 Mcglothlin Mark W Infusion catheters with slit valves and of simplified construction
US9414752B2 (en) 2012-11-09 2016-08-16 Elwha Llc Embolism deflector
US20140328892A1 (en) * 2013-04-04 2014-11-06 Jullia Y. Lee Use of alfimeprase in the treatment of thrombosis

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4610879A (en) * 1984-01-06 1986-09-09 University Of Southern California Fibrinolytic enzyme from snake vernom
US5260060A (en) * 1991-08-09 1993-11-09 University Of Southern California Fibrinolytic enzymes
US5626564A (en) * 1995-03-31 1997-05-06 Creighton University Adjustable sideholes catheter
WO1998024917A1 (en) * 1996-12-02 1998-06-11 Diatide, Inc. Thrombolytic agents with antithrombotic activity
US5922322A (en) * 1995-05-17 1999-07-13 New York Blood Center, Inc. Fibrin(ogen) degradation and clot lysis by fibrinolytic matrix metalloproteinase
WO2001043765A2 (en) * 1999-12-17 2001-06-21 Amgen Inc. Method for localized administration of fibrinolytic metalloproteinases

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4447236A (en) 1982-02-05 1984-05-08 Cordis Corporation Infusion catheter system
US5000185A (en) 1986-02-28 1991-03-19 Cardiovascular Imaging Systems, Inc. Method for intravascular two-dimensional ultrasonography and recanalization
ZA889415B (en) 1987-12-18 1989-09-27 Chiron Corp Compositions and method for recombinant production of crotalidus venum fibrolase
WO1990007352A1 (en) 1989-01-04 1990-07-12 Boston Scientific Corporation Angioplasty catheter
US5709676A (en) 1990-02-14 1998-01-20 Alt; Eckhard Synergistic treatment of stenosed blood vessels using shock waves and dissolving medication
US6020181A (en) * 1995-05-17 2000-02-01 New York Blood, Inc. Inhibition of thrombus formation by medical related apparatus comprising treating with fibrinolytic matrix metalloproteinase
US5741779A (en) * 1996-05-10 1998-04-21 Xoma Corporation Antithrombotic materials and methods
US6440414B1 (en) 1999-10-01 2002-08-27 Amgen Inc. Pharmaceutical compositions of fibrinolytic agent
US6261820B1 (en) 1999-10-01 2001-07-17 Amgen Inc. Fibronolytically active polypeptide

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4610879A (en) * 1984-01-06 1986-09-09 University Of Southern California Fibrinolytic enzyme from snake vernom
US5260060A (en) * 1991-08-09 1993-11-09 University Of Southern California Fibrinolytic enzymes
US5626564A (en) * 1995-03-31 1997-05-06 Creighton University Adjustable sideholes catheter
US5922322A (en) * 1995-05-17 1999-07-13 New York Blood Center, Inc. Fibrin(ogen) degradation and clot lysis by fibrinolytic matrix metalloproteinase
WO1998024917A1 (en) * 1996-12-02 1998-06-11 Diatide, Inc. Thrombolytic agents with antithrombotic activity
WO2001043765A2 (en) * 1999-12-17 2001-06-21 Amgen Inc. Method for localized administration of fibrinolytic metalloproteinases

Also Published As

Publication number Publication date
ES2242655T3 (es) 2005-11-16
AU784252B2 (en) 2006-03-02
EP1645282A1 (en) 2006-04-12
US6455269B1 (en) 2002-09-24
WO2001043765A2 (en) 2001-06-21
CA2394613A1 (en) 2001-06-21
AU2434601A (en) 2001-06-25
WO2001043765A3 (en) 2002-01-17
PT1239873E (pt) 2005-10-31
DE60021111D1 (de) 2005-08-04
ATE298585T1 (de) 2005-07-15
EP1239873B1 (en) 2005-06-29
JP2003517020A (ja) 2003-05-20
HK1050845B (en) 2005-11-04
DK1239873T3 (da) 2005-08-29
EP1239873A2 (en) 2002-09-18
MXPA02006024A (es) 2002-12-05
DE60021111T2 (de) 2006-05-11
HK1050845A1 (en) 2003-07-11

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