SG165394G - Mercapto-or acylthio-trifluoromethyl amide derivatives and their use - Google Patents
Mercapto-or acylthio-trifluoromethyl amide derivatives and their useInfo
- Publication number
- SG165394G SG165394G SG165394A SG165394A SG165394G SG 165394 G SG165394 G SG 165394G SG 165394 A SG165394 A SG 165394A SG 165394 A SG165394 A SG 165394A SG 165394 G SG165394 G SG 165394G
- Authority
- SG
- Singapore
- Prior art keywords
- carbons
- acylthio
- mercapto
- halo
- chem
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/02—Thiols having mercapto groups bound to acyclic carbon atoms
- C07C321/04—Thiols having mercapto groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/59—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with at least one of the bonds being to sulfur
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Indole Compounds (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Priority Applications (27)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002038379A CA2038379C (en) | 1990-03-22 | 1991-03-15 | Trifluoromethyl mercaptan and mercaptoacyl derivatives and method of using same |
NO911149A NO175147C (no) | 1990-03-22 | 1991-03-21 | Analogifremgangsmåte for fremstilling av merkaptan- og merkaptoacyl-derivater |
SK765-91A SK279617B6 (sk) | 1990-03-22 | 1991-03-21 | Trifluórmetylmerkaptánové a merkaptoacylové derivá |
IL9762691A IL97626A (en) | 1990-03-22 | 1991-03-21 | History of triplooromethyl mercaptan and mercaptoacyl, processes for their preparation and pharmaceutical preparations containing them |
HU91956A HU210313B (en) | 1990-03-22 | 1991-03-21 | Process for the preparation of trifluoromethyl mercaptan and mercaptoacyl derivatives and pharmaceutical compositions containing the same |
ZA912133A ZA912133B (en) | 1990-03-22 | 1991-03-21 | Trifluoromethyl mercaptan and mercaptoacyl derivatives and method of using same |
AU73672/91A AU632408B2 (en) | 1990-03-22 | 1991-03-21 | Trifluoromethyl mercaptan and mercaptoacyl derivatives and method of using same |
CS91765A CZ281165B6 (cs) | 1990-03-22 | 1991-03-21 | Trifluormethylmerkaptanové a merkaptoacylové deriváty a způsob jejich přípravy a použití |
IE94191A IE65539B1 (en) | 1990-03-22 | 1991-03-21 | Trifluoromethyl mercaptan and mercaptoacyl derivatives and method of using same |
NZ237534A NZ237534A (en) | 1990-03-22 | 1991-03-21 | Mercapto-substituted amide derivatives and pharmaceutical compositions |
PL91289549A PL165153B1 (pl) | 1990-03-22 | 1991-03-22 | Sposób wytwarzania nowych pochodnych merkaptoaikanokarbonamidów PL PL PL PL |
AT91302508T ATE110056T1 (de) | 1990-03-22 | 1991-03-22 | Merkapto- oder acylthio- trifluoromethylamidderivate und ihre verwendung. |
KR1019910004553A KR0184876B1 (ko) | 1990-03-22 | 1991-03-22 | 트리플루오로메틸 머캅탄 및 머캅토아실 유도체 및 그의 사용 방법 |
MX2503591A MX25035A (es) | 1990-03-22 | 1991-03-22 | Derivados de mercaptoacilo y mercaptano de trifluorometilo y procedimiento para su preparacion. |
SU914895195A RU2024504C1 (ru) | 1990-03-22 | 1991-03-22 | Способ получения производных трифторметилмеркаптана |
FI911399A FI112213B (fi) | 1990-03-22 | 1991-03-22 | Menetelmä terapeuttisesti käyttökelpoisten trifluorimetyylimerkaptaani- ja merkaptoasyylijohdannaisten valmistamiseksi |
DK91302508.6T DK0449523T3 (da) | 1990-03-22 | 1991-03-22 | Fremgangsmåde til fremstilling af phenoler |
CN91102697A CN1038505C (zh) | 1990-03-22 | 1991-03-22 | 三氟甲基硫醇和巯酰基衍生物及其制备方法 |
ES91302508T ES2057761T3 (es) | 1990-03-22 | 1991-03-22 | Derivados de mercapto- o aciltio-trifluorometil-amidas y su uso. |
EP91302508A EP0449523B1 (de) | 1990-03-22 | 1991-03-22 | Merkapto- oder Acylthio-trifluoromethylamidderivate und ihre Verwendung |
PT97121A PT97121B (pt) | 1990-03-22 | 1991-03-22 | Processo para a preparcao de derivados de trifluorometil-mercaptano e de mercaptoacilo |
DE69103454T DE69103454T2 (de) | 1990-03-22 | 1991-03-22 | Merkapto- oder Acylthio-trifluoromethylamidderivate und ihre Verwendung. |
JP3083522A JP2955051B2 (ja) | 1990-03-22 | 1991-03-22 | トリフルオロメチルメルカプタンおよびメルカプトアシル誘導体 |
EG16091A EG19711A (en) | 1990-03-22 | 1991-03-23 | Trifluromethyl mercaptan and mercaptoacyl derivatives and method of using same |
SG165394A SG165394G (en) | 1990-03-22 | 1994-11-16 | Mercapto-or acylthio-trifluoromethyl amide derivatives and their use |
HK24295A HK24295A (en) | 1990-03-22 | 1995-02-23 | Mercapto- or acylthio-trifluoromethyl amide derivatives and their use |
CY182095A CY1820A (en) | 1990-03-22 | 1995-10-20 | Mercapto-or acylthio-trifluoromethyl amide derivatives and their use |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49738690A | 1990-03-22 | 1990-03-22 | |
SG165394A SG165394G (en) | 1990-03-22 | 1994-11-16 | Mercapto-or acylthio-trifluoromethyl amide derivatives and their use |
Publications (1)
Publication Number | Publication Date |
---|---|
SG165394G true SG165394G (en) | 1995-04-28 |
Family
ID=26664489
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG165394A SG165394G (en) | 1990-03-22 | 1994-11-16 | Mercapto-or acylthio-trifluoromethyl amide derivatives and their use |
Country Status (27)
Country | Link |
---|---|
EP (1) | EP0449523B1 (de) |
JP (1) | JP2955051B2 (de) |
KR (1) | KR0184876B1 (de) |
CN (1) | CN1038505C (de) |
AT (1) | ATE110056T1 (de) |
AU (1) | AU632408B2 (de) |
CA (1) | CA2038379C (de) |
CY (1) | CY1820A (de) |
CZ (1) | CZ281165B6 (de) |
DE (1) | DE69103454T2 (de) |
DK (1) | DK0449523T3 (de) |
EG (1) | EG19711A (de) |
ES (1) | ES2057761T3 (de) |
FI (1) | FI112213B (de) |
HK (1) | HK24295A (de) |
HU (1) | HU210313B (de) |
IE (1) | IE65539B1 (de) |
IL (1) | IL97626A (de) |
MX (1) | MX25035A (de) |
NO (1) | NO175147C (de) |
NZ (1) | NZ237534A (de) |
PL (1) | PL165153B1 (de) |
PT (1) | PT97121B (de) |
RU (1) | RU2024504C1 (de) |
SG (1) | SG165394G (de) |
SK (1) | SK279617B6 (de) |
ZA (1) | ZA912133B (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1273455B (it) * | 1995-01-27 | 1997-07-08 | Zambon Spa | Derivati tiolici ad attivita' inibitrice delle metallopeptidasi |
IT1277736B1 (it) * | 1995-12-28 | 1997-11-12 | Zambon Spa | Derivati tiolici ad attivita' inibitrice delle metallopeptidasi |
FR2805259B1 (fr) * | 2000-02-17 | 2002-03-29 | Inst Nat Sante Rech Med | Nouveaux derives d'aminoacides n-mercaptoacyles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
AR044519A1 (es) | 2003-05-02 | 2005-09-14 | Novartis Ag | Derivados de piridin-tiazol amina y de pirimidin-tiazol amina |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE429374B (sv) * | 1980-04-15 | 1983-08-29 | Luxor Ab | Feste |
FR2480747A1 (fr) * | 1980-04-17 | 1981-10-23 | Roques Bernard | Derives d'acides amines et leur application therapeutique |
US4333943A (en) * | 1980-04-24 | 1982-06-08 | Miles Laboratories, Inc. | Ethyl 3-(3-indolyl)-3-(5-tetrazolyl) propionate compounds used as anti-hypertensive agents |
BE890948A (fr) * | 1981-10-30 | 1982-02-15 | Luitpold Werk Chem Pharm | Derives de l'acide anthranilique |
EP0361365A1 (de) * | 1988-09-30 | 1990-04-04 | E.R. SQUIBB & SONS, INC. | Derivate von Aminobenzoesäure und Aminocyclohexancarbonsäure, Zusammensetzungen und ihre Verwendung |
-
1991
- 1991-03-15 CA CA002038379A patent/CA2038379C/en not_active Expired - Fee Related
- 1991-03-21 IL IL9762691A patent/IL97626A/en not_active IP Right Cessation
- 1991-03-21 SK SK765-91A patent/SK279617B6/sk unknown
- 1991-03-21 CZ CS91765A patent/CZ281165B6/cs not_active IP Right Cessation
- 1991-03-21 NO NO911149A patent/NO175147C/no not_active IP Right Cessation
- 1991-03-21 NZ NZ237534A patent/NZ237534A/en unknown
- 1991-03-21 HU HU91956A patent/HU210313B/hu not_active IP Right Cessation
- 1991-03-21 ZA ZA912133A patent/ZA912133B/xx unknown
- 1991-03-21 IE IE94191A patent/IE65539B1/en not_active IP Right Cessation
- 1991-03-21 AU AU73672/91A patent/AU632408B2/en not_active Ceased
- 1991-03-22 KR KR1019910004553A patent/KR0184876B1/ko not_active IP Right Cessation
- 1991-03-22 DK DK91302508.6T patent/DK0449523T3/da active
- 1991-03-22 MX MX2503591A patent/MX25035A/es unknown
- 1991-03-22 PL PL91289549A patent/PL165153B1/pl not_active IP Right Cessation
- 1991-03-22 PT PT97121A patent/PT97121B/pt not_active IP Right Cessation
- 1991-03-22 FI FI911399A patent/FI112213B/fi active
- 1991-03-22 EP EP91302508A patent/EP0449523B1/de not_active Expired - Lifetime
- 1991-03-22 RU SU914895195A patent/RU2024504C1/ru active
- 1991-03-22 AT AT91302508T patent/ATE110056T1/de not_active IP Right Cessation
- 1991-03-22 CN CN91102697A patent/CN1038505C/zh not_active Expired - Fee Related
- 1991-03-22 JP JP3083522A patent/JP2955051B2/ja not_active Expired - Fee Related
- 1991-03-22 ES ES91302508T patent/ES2057761T3/es not_active Expired - Lifetime
- 1991-03-22 DE DE69103454T patent/DE69103454T2/de not_active Expired - Fee Related
- 1991-03-23 EG EG16091A patent/EG19711A/xx active
-
1994
- 1994-11-16 SG SG165394A patent/SG165394G/en unknown
-
1995
- 1995-02-23 HK HK24295A patent/HK24295A/xx not_active IP Right Cessation
- 1995-10-20 CY CY182095A patent/CY1820A/xx unknown
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