SG165300A1 - Reactive heterocycle-substituted 7-hydroxycoumarins and their conjugates - Google Patents

Reactive heterocycle-substituted 7-hydroxycoumarins and their conjugates

Info

Publication number
SG165300A1
SG165300A1 SG201002257-2A SG2010022572A SG165300A1 SG 165300 A1 SG165300 A1 SG 165300A1 SG 2010022572 A SG2010022572 A SG 2010022572A SG 165300 A1 SG165300 A1 SG 165300A1
Authority
SG
Singapore
Prior art keywords
substituted
heterocycle
hydroxycoumarin
dyes
conjugates
Prior art date
Application number
SG201002257-2A
Other languages
English (en)
Inventor
Zhenjun Diwu
Timothy Dubrovsky
Barnaby Abrams
Jinfang Liao
Qinglin Meng
Original Assignee
Becton Dickinson Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson Co filed Critical Becton Dickinson Co
Publication of SG165300A1 publication Critical patent/SG165300A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B57/00—Other synthetic dyes of known constitution
    • C09B57/02—Coumarine dyes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/13—Tracers or tags

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
SG201002257-2A 2009-04-01 2010-03-31 Reactive heterocycle-substituted 7-hydroxycoumarins and their conjugates SG165300A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16586209P 2009-04-01 2009-04-01
US12/726,267 US8431416B2 (en) 2009-04-01 2010-03-17 Reactive heterocycle-substituted 7-hydroxycoumarins and their conjugates

Publications (1)

Publication Number Publication Date
SG165300A1 true SG165300A1 (en) 2010-10-28

Family

ID=42224506

Family Applications (1)

Application Number Title Priority Date Filing Date
SG201002257-2A SG165300A1 (en) 2009-04-01 2010-03-31 Reactive heterocycle-substituted 7-hydroxycoumarins and their conjugates

Country Status (6)

Country Link
US (1) US8431416B2 (fr)
EP (1) EP2236508B1 (fr)
JP (1) JP5697886B2 (fr)
CN (1) CN101914093B (fr)
ES (1) ES2548380T3 (fr)
SG (1) SG165300A1 (fr)

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US9400273B1 (en) 2009-12-09 2016-07-26 Life Technologies Corporation 7-hydroxycoumarin-based cell-tracking reagents
JP6425538B2 (ja) * 2011-03-30 2018-11-21 スリーエム イノベイティブ プロパティズ カンパニー 蛍光性化合物又は発蛍光団化合物、並びにこれらの使用法
CN103360377B (zh) * 2012-03-29 2017-09-19 住友化学株式会社 染料用化合物
WO2014066552A1 (fr) 2012-10-24 2014-05-01 Becton, Dickinson And Company Colorants d'hydroxamate d'azaindoline-cyanine substitués et leurs bioconjugués
AU2016285929B2 (en) * 2015-06-29 2022-01-06 Immunogen, Inc. Conjugates of cysteine engineered antibodies
ITUA20161706A1 (it) 2016-03-15 2017-09-15 Cyanagen S R L Nuovi coloranti cumarinici e relativi coniugati
EP3889237B1 (fr) 2016-04-15 2022-12-28 Beckman Coulter, Inc. Macromolécules photoactives et leurs utilisations
JP6821490B2 (ja) * 2017-04-03 2021-01-27 日本化薬株式会社 クマリン化合物又はそれらの塩、並びにこれを含んだ顔料組成物
GB201716931D0 (en) * 2017-10-16 2017-11-29 Illumina Cambridge Ltd New fluorescent compounds and their use as biomarkers
EP3914912A1 (fr) * 2019-01-21 2021-12-01 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Méthodes avancées d'identification haute performance automatisée de glucides et de motifs de composition de mélange de glucides et systèmes correspondants, ainsi que méthodes d'étalonnage de systèmes de détection de fluorescence à longueurs d'onde multiples correspondantes, fondées sur de nouveaux colorants fluorescents
CN109721592B (zh) * 2019-03-04 2022-09-30 河南理工大学 一种含香豆素的氨基吡嗪酰腙衍生物的荧光探针及其制备方法和应用
EP3747957A1 (fr) 2019-06-07 2020-12-09 Universidade de Évora Colorants fluorescents de coumarines de vinyle tiophene et de bitiophene et leur procede de synthese
CN112679569B (zh) * 2020-10-22 2022-05-27 山西大学 一种荧光探针及其制备方法和应用
EP4288776A1 (fr) 2021-02-05 2023-12-13 Beckman Coulter, Inc. Compositions et méthodes pour la prévention d'interactions non spécifiques entre des conjugués colorants polymères-anticorps
CN113121513B (zh) * 2021-04-26 2023-05-16 安徽大学 一种咔唑-香豆素基腙类化合物及其制备方法和用途
EP4334395A1 (fr) 2021-05-04 2024-03-13 Beckman Coulter, Inc. Polymères absorbant les uv, compositions et utilisations de ceux-ci

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Also Published As

Publication number Publication date
EP2236508A1 (fr) 2010-10-06
JP5697886B2 (ja) 2015-04-08
ES2548380T3 (es) 2015-10-16
US20100255504A1 (en) 2010-10-07
JP2010254993A (ja) 2010-11-11
US8431416B2 (en) 2013-04-30
EP2236508B1 (fr) 2015-08-26
CN101914093A (zh) 2010-12-15
CN101914093B (zh) 2015-08-26

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