SG156645A1 - Method for cleaning 3-hydroxyamidinophenylalanine derivatives by the precipitation and recrystallization of salt and an aromatic sulfonic acid - Google Patents

Method for cleaning 3-hydroxyamidinophenylalanine derivatives by the precipitation and recrystallization of salt and an aromatic sulfonic acid

Info

Publication number
SG156645A1
SG156645A1 SG200906861-0A SG2009068610A SG156645A1 SG 156645 A1 SG156645 A1 SG 156645A1 SG 2009068610 A SG2009068610 A SG 2009068610A SG 156645 A1 SG156645 A1 SG 156645A1
Authority
SG
Singapore
Prior art keywords
recrystallization
precipitation
cleaning
salt
derivatives
Prior art date
Application number
SG200906861-0A
Other languages
English (en)
Inventor
Helmut Greiving
Original Assignee
Wilex Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wilex Ag filed Critical Wilex Ag
Publication of SG156645A1 publication Critical patent/SG156645A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
SG200906861-0A 2004-10-14 2005-10-14 Method for cleaning 3-hydroxyamidinophenylalanine derivatives by the precipitation and recrystallization of salt and an aromatic sulfonic acid SG156645A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04024553 2004-10-14

Publications (1)

Publication Number Publication Date
SG156645A1 true SG156645A1 (en) 2009-11-26

Family

ID=35462142

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200906861-0A SG156645A1 (en) 2004-10-14 2005-10-14 Method for cleaning 3-hydroxyamidinophenylalanine derivatives by the precipitation and recrystallization of salt and an aromatic sulfonic acid

Country Status (16)

Country Link
US (1) US7951943B2 (zh)
EP (1) EP1799665B1 (zh)
JP (1) JP5096157B2 (zh)
KR (1) KR101106652B1 (zh)
CN (1) CN101039928B (zh)
AT (1) ATE440092T1 (zh)
AU (1) AU2005297610B2 (zh)
BR (1) BRPI0516106B1 (zh)
CA (1) CA2583771C (zh)
DE (1) DE502005007959D1 (zh)
ES (1) ES2328052T3 (zh)
HK (1) HK1101170A1 (zh)
MX (1) MX2007004191A (zh)
RU (1) RU2391336C2 (zh)
SG (1) SG156645A1 (zh)
WO (1) WO2006042678A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2022011173A (es) 2020-03-10 2022-10-18 Redhill Biopharma Ltd Tratamiento de infeccion por coronavirus.
US11471448B2 (en) 2020-12-15 2022-10-18 Redhill Biopharma Ltd. Sphingosine kinase 2 inhibitor for treating coronavirus infection in moderately severe patients with pneumonia

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4375430A (en) * 1981-09-08 1983-03-01 Pfizer Inc. Processes for preparation, isolation and purification of dipeptide sweeteners
JPH10237030A (ja) * 1997-02-26 1998-09-08 Ajinomoto Co Inc 分岐鎖アミノ酸の精製法
ATE386029T1 (de) * 2001-03-21 2008-03-15 Wilex Ag Urokinase-inhibitoren
SI21137A (sl) * 2002-01-24 2003-08-31 LEK, tovarna farmacevtskih in kemičnih izdelkov, d.d. Derivati azafenilalanina
CH695999A5 (de) * 2002-02-28 2006-11-15 Wilex Ag Verfahren zur Herstellung von 3- Amidinophenylalanin-Derivaten.

Also Published As

Publication number Publication date
RU2391336C2 (ru) 2010-06-10
MX2007004191A (es) 2007-06-11
CN101039928A (zh) 2007-09-19
DE502005007959D1 (de) 2009-10-01
US20080039626A1 (en) 2008-02-14
BRPI0516106B1 (pt) 2021-08-24
CA2583771A1 (en) 2006-04-27
ATE440092T1 (de) 2009-09-15
KR20070063591A (ko) 2007-06-19
JP5096157B2 (ja) 2012-12-12
EP1799665A1 (de) 2007-06-27
AU2005297610B2 (en) 2011-05-19
CN101039928B (zh) 2010-12-08
KR101106652B1 (ko) 2012-01-18
JP2008516908A (ja) 2008-05-22
ES2328052T3 (es) 2009-11-06
EP1799665B1 (de) 2009-08-19
US20090099360A9 (en) 2009-04-16
AU2005297610A1 (en) 2006-04-27
US7951943B2 (en) 2011-05-31
CA2583771C (en) 2013-08-27
HK1101170A1 (en) 2007-10-12
BRPI0516106A (pt) 2008-08-26
RU2007117751A (ru) 2008-11-20
WO2006042678A1 (de) 2006-04-27

Similar Documents

Publication Publication Date Title
WO2009066152A3 (en) Haloallylamine inhibitors of ssao/vap-1 and uses therefor
CA2818187C (en) Bromodomain inhibitors and uses thereof
WO2005051358A8 (en) Composition and method for enhancing bioavailability
MY147994A (en) Azabiphenylaminobenzoic acid derivatives as dhodh inhibitors
UA94052C2 (uk) Похідні піридазину
UA83875C2 (ru) Производные хинолина для применения в качестве микобактериальных ингибиторов
MX2009006700A (es) Derivados de 5-ciano-4-(pirolo)[2,3b]piridina-3-il)-pirimidinas utiles como inhibidores de proteina-cinasas.
MX2009008253A (es) Derivados de 2-aminopiridina utiles como inhibidores de cinasa.
MX2009006345A (es) Compuestos utiles como inhibidores de proteina cinasa.
SG170828A1 (en) Deazapurines useful as inhibitors of janus kinases
TW200633980A (en) Pyridones useful as inhibitors of kinases
SG148178A1 (en) Indozolone derivatives as 11b-hsd1 inhibitors
HK1113569A1 (en) Pyrazolo
WO2007095223A3 (en) Pyrrolo(3,2-c) pyridines useful as inhibitors of protein kinases
WO2010011772A3 (en) Tri-cyclic pyrazolopyridine kinase inhibitors
NO20083708L (no) 4-Fenyl-tiazol-5-karboksylsyre og 4-fenyl-tiazol-5-karboksylmider som PLK1-inhibitorer
WO2007146284A3 (en) Thienopyrimidines useful as modulators of ion channels
WO2007092343A3 (en) Novel epoprostenol formulation and method of making thereof
TW200718695A (en) Novel piperidine carboxylic acid amide derivatives
MX2007002833A (es) Derivados de alquiliden-tetrahidronaftaleno, procedimiento para su preparacion y su uso como antiinflamatorios.
MX343234B (es) Formas cristalinas de 6-(1h-imidazol-1-il)-2-fenilquinazolina.
WO2007095117A3 (en) Method for improving the oral administration of alpha-lipoic acid
EA201490363A1 (ru) Новые составы на основе (триметоксифениламино)пиримидинилов
ZA200900165B (en) 4-amino-3-arylamino-6-arylpyrazolo[3,4-D]pyrimidine derivatives, methods for their preparation and their use as antiviral agents
SG156645A1 (en) Method for cleaning 3-hydroxyamidinophenylalanine derivatives by the precipitation and recrystallization of salt and an aromatic sulfonic acid