SG11202110468YA - Methods and compositions for analyzing nucleic acid - Google Patents

Methods and compositions for analyzing nucleic acid

Info

Publication number
SG11202110468YA
SG11202110468YA SG11202110468YA SG11202110468YA SG11202110468YA SG 11202110468Y A SG11202110468Y A SG 11202110468YA SG 11202110468Y A SG11202110468Y A SG 11202110468YA SG 11202110468Y A SG11202110468Y A SG 11202110468YA SG 11202110468Y A SG11202110468Y A SG 11202110468YA
Authority
SG
Singapore
Prior art keywords
oligonucleotide
nucleic acid
scaffold
ssna
composition
Prior art date
Application number
SG11202110468YA
Other languages
English (en)
Inventor
Kincaid Kelly M Harkins
Colin Naughton
Varsha Rao
Christopher Troll
Joshua Kapp
Original Assignee
Claret Bioscience Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=70465467&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11202110468Y(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Claret Bioscience Llc filed Critical Claret Bioscience Llc
Publication of SG11202110468YA publication Critical patent/SG11202110468YA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00—Production
    • C12N2330/30—Production chemically synthesised
    • C12N2330/31—Libraries, arrays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
SG11202110468YA 2019-04-05 2020-04-02 Methods and compositions for analyzing nucleic acid SG11202110468YA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962830211P 2019-04-05 2019-04-05
US201962861594P 2019-06-14 2019-06-14
US201962925132P 2019-10-23 2019-10-23
PCT/US2020/026421 WO2020206143A1 (en) 2019-04-05 2020-04-02 Methods and compositions for analyzing nucleic acid

Publications (1)

Publication Number Publication Date
SG11202110468YA true SG11202110468YA (en) 2021-10-28

Family

ID=70465467

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202110468YA SG11202110468YA (en) 2019-04-05 2020-04-02 Methods and compositions for analyzing nucleic acid

Country Status (10)

Country Link
US (1) US20220348906A1 (enExample)
EP (2) EP4538390A3 (enExample)
JP (2) JP7651470B2 (enExample)
KR (1) KR20210148304A (enExample)
CN (1) CN114174530A (enExample)
AU (1) AU2020253471B2 (enExample)
CA (1) CA3134831A1 (enExample)
IL (1) IL286945A (enExample)
SG (1) SG11202110468YA (enExample)
WO (1) WO2020206143A1 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019236726A1 (en) 2018-06-06 2019-12-12 The Regents Of The University Of California Methods of producing nucleic acid libraries and compositions and kits for practicing same
WO2021007462A1 (en) * 2019-07-09 2021-01-14 The Translational Genomics Research Institute METHODS OF DETECTING DISEASE AND TREATMENT RESPONSE IN cfDNA
US20230014607A1 (en) 2019-10-09 2023-01-19 Claret Bioscience, Llc Methods and compositions for analyzing nucleic acid
CN110669830B (zh) * 2019-10-24 2023-05-23 裕策医疗器械江苏有限公司 一种低质量ffpe dna的处理方法、装置和存储介质
EP4342999B1 (en) * 2020-01-16 2025-06-11 DNAe Diagnostics Limited Compositions, kits and methods for isolating target polynucleotides
DK4172357T3 (da) * 2020-06-24 2024-08-05 Claret Bioscience Llc Fremgangsmåder og sammensætninger til analyse af nucleinsyrer
WO2022020346A1 (en) 2020-07-21 2022-01-27 Claret Bioscience, Llc Cancer detection, monitoring, and reporting from sequencing cell-free dna
WO2022076574A1 (en) 2020-10-08 2022-04-14 Claret Bioscience, Llc Methods and compositions for analyzing nucleic acid
TW202242130A (zh) * 2020-12-29 2022-11-01 比利時商比利時意志有限公司 循環轉錄因子分析
US20250304953A1 (en) * 2021-02-18 2025-10-02 Seoul National University R&Db Foundation Method for purifying nucleic acid library
BR112023019154A2 (pt) * 2021-03-31 2023-10-17 Illumina Cambridge Ltd Técnicas de sequenciamento de bibliotecas de ácidos nucleicos com detecção de dímero de adaptador
CN115197998A (zh) * 2021-04-13 2022-10-18 广东菲鹏生物有限公司 一种单链核酸分子测序文库构建方法
GB2606158B (en) * 2021-04-26 2023-12-27 Wobble Genomics Ltd Amplification of single stranded DNA
US20240344056A1 (en) * 2021-06-04 2024-10-17 Somagenics, Inc. Improved method of sequencing library preparation for short dna
WO2023063958A1 (en) * 2021-10-15 2023-04-20 Qiagen Sciences, Llc Methods for producing dna libraries and uses thereof
US20250019693A1 (en) * 2022-02-17 2025-01-16 Claret Bioscience, Llc Methods and compositions for analyzing nucleic acid
US20250382607A1 (en) * 2022-05-17 2025-12-18 Nanjing GenScript Biotech Co., Ltd. Sgrna sequencing linker and use thereof
TW202405189A (zh) * 2022-06-28 2024-02-01 南韓商西諾海利斯股份有限公司 用於核糖核酸鹼基序列分析的樣本庫製備方法
US20260078439A1 (en) * 2022-08-24 2026-03-19 The Regents Of The University Of California Next-Generation Sequencing Pipeline for Detection of Ultrashort Single-Stranded Cell-Free DNA
WO2024054517A1 (en) * 2022-09-08 2024-03-14 Claret Bioscience, Llc Methods and compositions for analyzing nucleic acid
CN116426607A (zh) * 2022-12-23 2023-07-14 南京诺唯赞生物科技股份有限公司 一种dna建库预混液
WO2024192634A1 (zh) * 2023-03-20 2024-09-26 深圳华大智造科技股份有限公司 一种高效且快速进行核酸文库构建的方法
EP4724637A1 (en) * 2023-06-07 2026-04-15 Claret Bioscience, LLC Methods and compositions for analyzing nucleic acid
CN121969766A (zh) 2023-08-31 2026-05-01 因美纳有限公司 适体检测技术
EP4784792A1 (en) * 2023-09-28 2026-08-05 The Regents of the University of California Methods and compositions for producing sequencing libraries
WO2025179170A2 (en) * 2024-02-22 2025-08-28 Canal Biosciences, Inc. Single-stranded end preserving adaptors
WO2026058704A1 (ja) * 2024-09-10 2026-03-19 国立大学法人 東京大学 Dnaバーコード配列を含む一本鎖 dnaの合成方法(method for synthesizing single-stranded dna containing dna barcode sequences)

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6927028B2 (en) 2001-08-31 2005-08-09 Chinese University Of Hong Kong Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA
EP1817430B1 (en) 2004-11-29 2009-09-16 Klinikum der Universität Regensburg Means and methods for detecting methylated dna
EP3260556B1 (en) 2006-05-31 2019-07-31 Sequenom, Inc. Methods for the extraction of nucleic acid from a sample
EP2038426A2 (en) 2006-06-16 2009-03-25 Sequenom, Inc. Methods and compositions for the amplification, detection and quantification of nucleic acid from a sample
WO2009032779A2 (en) 2007-08-29 2009-03-12 Sequenom, Inc. Methods and compositions for the size-specific seperation of nucleic acid from a sample
WO2009032781A2 (en) 2007-08-29 2009-03-12 Sequenom, Inc. Methods and compositions for universal size-specific polymerase chain reaction
WO2009120808A2 (en) 2008-03-26 2009-10-01 Sequenom, Inc. Restriction endonuclease enhanced polymorphic sequence detection
US8476013B2 (en) 2008-09-16 2013-07-02 Sequenom, Inc. Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
EP3103871B1 (en) 2008-09-16 2020-07-29 Sequenom, Inc. Processes for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for fetal nucleic acid quantification
US8771948B2 (en) 2009-04-03 2014-07-08 Sequenom, Inc. Nucleic acid preparation compositions and methods
SG185544A1 (en) 2010-05-14 2012-12-28 Fluidigm Corp Nucleic acid isolation methods
WO2013019361A1 (en) 2011-07-07 2013-02-07 Life Technologies Corporation Sequencing methods
DK2748357T3 (en) 2011-09-07 2018-07-16 X Chem Inc Methods for labeling DNA-encoded libraries
CA2877094A1 (en) 2012-06-18 2013-12-27 Nugen Technologies, Inc. Compositions and methods for negative selection of non-desired nucleic acid sequences
CN105189788B (zh) 2013-03-12 2018-07-13 纳幕尔杜邦公司 用于鉴定罕见切割工程化双链断裂诱导剂的变体识别位点的方法及其组合物和用途
EP3296408A1 (en) 2013-09-05 2018-03-21 The Jackson Laboratory Compositions for rna-chromatin interaction analysis and uses thereof
CN105441429A (zh) * 2014-08-08 2016-03-30 深圳华大基因科技有限公司 一种制备腺苷酰化接头的方法及腺苷酰化接头
US11014957B2 (en) * 2015-12-21 2021-05-25 Realseq Biosciences, Inc. Methods of library construction for polynucleotide sequencing
CN109563543B (zh) * 2016-07-15 2022-08-30 加利福尼亚大学董事会 产生核酸库的方法
KR102548274B1 (ko) * 2017-03-20 2023-06-27 일루미나, 인코포레이티드 핵산 라이브러리를 제조하기 위한 방법 및 조성물
CN118638898A (zh) 2017-03-23 2024-09-13 华盛顿大学 用于靶向核酸序列富集的方法及在错误纠正的核酸测序中的应用
US11198865B2 (en) 2017-11-02 2021-12-14 Amanda Raine Splinted ligation adapter tagging
CN119432800A (zh) 2018-05-16 2025-02-14 生物辐射实验室股份有限公司 处理核酸样本的方法
WO2019236726A1 (en) * 2018-06-06 2019-12-12 The Regents Of The University Of California Methods of producing nucleic acid libraries and compositions and kits for practicing same
AU2019282812B2 (en) 2018-06-07 2025-08-14 Arc Bio, Llc Compositions and methods for making guide nucleic acids

Also Published As

Publication number Publication date
EP4538390A2 (en) 2025-04-16
EP3947723C0 (en) 2024-12-18
KR20210148304A (ko) 2021-12-07
CA3134831A1 (en) 2020-10-08
EP3947723A1 (en) 2022-02-09
EP4538390A3 (en) 2025-07-09
IL286945A (en) 2021-12-01
CN114174530A (zh) 2022-03-11
JP2025014018A (ja) 2025-01-28
JP7651470B2 (ja) 2025-03-26
US20220348906A1 (en) 2022-11-03
WO2020206143A9 (en) 2021-12-23
EP3947723B1 (en) 2024-12-18
WO2020206143A1 (en) 2020-10-08
AU2020253471B2 (en) 2026-07-30
JP2022528139A (ja) 2022-06-08
AU2020253471A1 (en) 2021-10-14

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