SG11202107732XA - Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells - Google Patents
Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cellsInfo
- Publication number
- SG11202107732XA SG11202107732XA SG11202107732XA SG11202107732XA SG11202107732XA SG 11202107732X A SG11202107732X A SG 11202107732XA SG 11202107732X A SG11202107732X A SG 11202107732XA SG 11202107732X A SG11202107732X A SG 11202107732XA SG 11202107732X A SG11202107732X A SG 11202107732XA
- Authority
- SG
- Singapore
- Prior art keywords
- dorsally
- pluripotent stem
- human pluripotent
- oligodendrocyte progenitor
- cells
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
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- C—CHEMISTRY; METALLURGY
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/113—Acidic fibroblast growth factor (aFGF, FGF-1)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/135—Platelet-derived growth factor [PDGF]
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/41—Hedgehog proteins; Cyclopamine (inhibitor)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2510/00—Genetically modified cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962796077P | 2019-01-23 | 2019-01-23 | |
| PCT/US2020/014834 WO2020154533A1 (en) | 2019-01-23 | 2020-01-23 | Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202107732XA true SG11202107732XA (en) | 2021-08-30 |
Family
ID=71609769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202107732XA SG11202107732XA (en) | 2019-01-23 | 2020-01-23 | Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11603518B2 (https=) |
| EP (1) | EP3914264A4 (https=) |
| JP (2) | JP7469317B2 (https=) |
| KR (2) | KR20260020476A (https=) |
| CN (2) | CN113474451B (https=) |
| AU (1) | AU2020210757B2 (https=) |
| CA (1) | CA3127213A1 (https=) |
| SG (1) | SG11202107732XA (https=) |
| WO (1) | WO2020154533A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116121189A (zh) | 2016-03-30 | 2023-05-16 | 阿斯特利亚斯生物治疗股份公司 | 少突胶质细胞祖细胞组合物 |
| IL281628B2 (en) | 2018-09-19 | 2025-06-01 | Lineage Cell Therapeutics Inc | Methods for differentiating pluripotent stem cells in dynamic suspension culture |
| WO2020154533A1 (en) | 2019-01-23 | 2020-07-30 | Asterias Biotherapeutics, Inc. | Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells |
| AU2022212124A1 (en) * | 2021-01-28 | 2023-08-10 | Asterias Biotherapeutics, Inc. | Compositions and methods for treating spinal cord injuries |
| IL305737A (en) * | 2021-03-10 | 2023-11-01 | Lineage Cell Therapeutics Inc | Methods for generating oligodendrocyte progenitor cells and their use |
| WO2023147512A2 (en) * | 2022-01-28 | 2023-08-03 | Asterias Biotherapeutics, Inc. | Compositions and methods for treating spinal cord injuries |
| CA3256595A1 (en) * | 2022-05-24 | 2023-11-30 | Bluerock Therapeutics Lp | METHODS FOR MANUFACTURED OLIGODENDROCYTE PROGENITOR CELLS |
| WO2025049991A1 (en) * | 2023-08-31 | 2025-03-06 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions comprising neurons and methods of using the same |
| KR20250094234A (ko) * | 2023-12-18 | 2025-06-25 | ㈜바이오솔빅스 | 콘케이브와 진탕배양 기법으로 형성된 전분화능 줄기세포 유래 신경세포 제조방법 및 이에 의해 제조된 3d 신경 오가노이드를 통한 약물 독성 평가방법 |
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| CN116121189A (zh) | 2016-03-30 | 2023-05-16 | 阿斯特利亚斯生物治疗股份公司 | 少突胶质细胞祖细胞组合物 |
| IL281628B2 (en) | 2018-09-19 | 2025-06-01 | Lineage Cell Therapeutics Inc | Methods for differentiating pluripotent stem cells in dynamic suspension culture |
| WO2020154533A1 (en) | 2019-01-23 | 2020-07-30 | Asterias Biotherapeutics, Inc. | Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells |
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2020
- 2020-01-23 WO PCT/US2020/014834 patent/WO2020154533A1/en not_active Ceased
- 2020-01-23 CN CN202080016840.0A patent/CN113474451B/zh active Active
- 2020-01-23 EP EP20745781.3A patent/EP3914264A4/en active Pending
- 2020-01-23 KR KR1020267000532A patent/KR20260020476A/ko active Pending
- 2020-01-23 US US16/750,975 patent/US11603518B2/en active Active
- 2020-01-23 SG SG11202107732XA patent/SG11202107732XA/en unknown
- 2020-01-23 CN CN202510214051.2A patent/CN120060141A/zh active Pending
- 2020-01-23 JP JP2021543274A patent/JP7469317B2/ja active Active
- 2020-01-23 KR KR1020217026687A patent/KR102910994B1/ko active Active
- 2020-01-23 AU AU2020210757A patent/AU2020210757B2/en active Active
- 2020-01-23 CA CA3127213A patent/CA3127213A1/en active Pending
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2022
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2024
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| US11603518B2 (en) | 2023-03-14 |
| CN120060141A (zh) | 2025-05-30 |
| AU2020210757B2 (en) | 2026-04-16 |
| JP2024096785A (ja) | 2024-07-17 |
| JP7469317B2 (ja) | 2024-04-16 |
| US20200231932A1 (en) | 2020-07-23 |
| WO2020154533A1 (en) | 2020-07-30 |
| KR20210121112A (ko) | 2021-10-07 |
| CA3127213A1 (en) | 2020-07-30 |
| EP3914264A1 (en) | 2021-12-01 |
| CN113474451B (zh) | 2025-06-10 |
| EP3914264A4 (en) | 2022-11-23 |
| CN113474451A (zh) | 2021-10-01 |
| KR102910994B1 (ko) | 2026-01-12 |
| JP2022520722A (ja) | 2022-04-01 |
| KR20260020476A (ko) | 2026-02-11 |
| AU2020210757A1 (en) | 2021-08-05 |
| US20230139899A1 (en) | 2023-05-04 |
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