SG11202107643YA - Internal cyclic sulphiamidine amide-aryl amide compound and use thereof for treating hepatitis b - Google Patents
Internal cyclic sulphiamidine amide-aryl amide compound and use thereof for treating hepatitis bInfo
- Publication number
- SG11202107643YA SG11202107643YA SG11202107643YA SG11202107643YA SG11202107643YA SG 11202107643Y A SG11202107643Y A SG 11202107643YA SG 11202107643Y A SG11202107643Y A SG 11202107643YA SG 11202107643Y A SG11202107643Y A SG 11202107643YA SG 11202107643Y A SG11202107643Y A SG 11202107643YA
- Authority
- SG
- Singapore
- Prior art keywords
- amide
- sulphiamidine
- treating hepatitis
- aryl
- internal cyclic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910027573.6A CN111434665B (zh) | 2019-01-11 | 2019-01-11 | 内环硫脒酰胺-芳基酰胺类化合物及其治疗乙型肝炎的用途 |
| PCT/CN2020/071523 WO2020143798A1 (fr) | 2019-01-11 | 2020-01-10 | Composé amide arylamide cyclique interne de sulphiamidine et son utilisation dans le traitement de l'hépatite b |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202107643YA true SG11202107643YA (en) | 2021-08-30 |
Family
ID=71520539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202107643YA SG11202107643YA (en) | 2019-01-11 | 2020-01-10 | Internal cyclic sulphiamidine amide-aryl amide compound and use thereof for treating hepatitis b |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20220380384A1 (fr) |
| EP (1) | EP3909957A4 (fr) |
| JP (1) | JP2022517984A (fr) |
| KR (1) | KR102650441B1 (fr) |
| CN (2) | CN111434665B (fr) |
| AU (1) | AU2020205923B2 (fr) |
| BR (1) | BR112021013730A2 (fr) |
| CA (1) | CA3126570A1 (fr) |
| MX (1) | MX2021008386A (fr) |
| SG (1) | SG11202107643YA (fr) |
| WO (1) | WO2020143798A1 (fr) |
| ZA (1) | ZA202105438B (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115177624A (zh) * | 2021-04-06 | 2022-10-14 | 上海长森药业有限公司 | 通过口服给药增加病毒空衣壳蛋白治疗hbv的方法 |
| CN115160344A (zh) * | 2021-04-06 | 2022-10-11 | 上海长森药业有限公司 | 通过口服给药抑制CD4+Treg细胞的药物和方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3085368A1 (fr) * | 2011-07-01 | 2016-10-26 | Baruch S. Blumberg Institute | Dérivés de la sulfamoylbenzamide en tant qu'agents antiviraux contre une infection vhb |
| US8629274B2 (en) | 2011-12-21 | 2014-01-14 | Novira Therapeutics, Inc. | Hepatitis B antiviral agents |
| MX367689B (es) * | 2014-02-06 | 2019-09-02 | Janssen Sciences Ireland Uc | Derivados de sulfamoilpirrolamida y su uso como medicamentos para el tratamiento de la hepatitis b. |
| AP2016009483A0 (en) * | 2014-04-11 | 2016-10-31 | Bayer Pharma AG | Novel macrocyclic compounds |
| US10875876B2 (en) * | 2015-07-02 | 2020-12-29 | Janssen Sciences Ireland Uc | Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B |
| CN108250121A (zh) * | 2016-12-28 | 2018-07-06 | 上海长森药业有限公司 | 磺酰胺-芳基酰胺类化合物及其治疗乙型肝炎的药物用途 |
| CN108264520B (zh) * | 2017-01-03 | 2021-12-07 | 上海长森药业有限公司 | 用于治疗乙型肝炎的化合物及其用途 |
| CN108341810B (zh) * | 2017-01-23 | 2022-01-18 | 上海长森药业有限公司 | 环硫脲类化合物及其用途 |
| WO2018153326A1 (fr) * | 2017-02-22 | 2018-08-30 | 上海长森药业有限公司 | Composé de sulfonyle hydrazine et son utilisation |
| CN109251212A (zh) * | 2017-07-14 | 2019-01-22 | 上海长森药业有限公司 | 内环硫醚酰胺-芳基酰胺类化合物及其治疗乙型肝炎的用途 |
| CN109251158B (zh) * | 2017-07-14 | 2023-05-23 | 上海长森药业有限公司 | 硫脒酰胺类化合物及其用于乙型肝炎治疗的用途 |
-
2019
- 2019-01-11 CN CN201910027573.6A patent/CN111434665B/zh active Active
-
2020
- 2020-01-10 AU AU2020205923A patent/AU2020205923B2/en active Active
- 2020-01-10 JP JP2021540294A patent/JP2022517984A/ja active Pending
- 2020-01-10 BR BR112021013730-0A patent/BR112021013730A2/pt unknown
- 2020-01-10 KR KR1020217025454A patent/KR102650441B1/ko active IP Right Grant
- 2020-01-10 CA CA3126570A patent/CA3126570A1/fr active Pending
- 2020-01-10 MX MX2021008386A patent/MX2021008386A/es unknown
- 2020-01-10 CN CN202080008964.4A patent/CN113286798B/zh active Active
- 2020-01-10 EP EP20738690.5A patent/EP3909957A4/fr active Pending
- 2020-01-10 US US17/421,819 patent/US20220380384A1/en active Pending
- 2020-01-10 WO PCT/CN2020/071523 patent/WO2020143798A1/fr unknown
- 2020-01-10 SG SG11202107643YA patent/SG11202107643YA/en unknown
-
2021
- 2021-07-30 ZA ZA2021/05438A patent/ZA202105438B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3909957A4 (fr) | 2022-09-07 |
| KR20210134621A (ko) | 2021-11-10 |
| US20220380384A1 (en) | 2022-12-01 |
| AU2020205923B2 (en) | 2022-12-01 |
| CA3126570A1 (fr) | 2020-07-16 |
| ZA202105438B (en) | 2022-09-28 |
| CN111434665B (zh) | 2023-03-10 |
| CN111434665A (zh) | 2020-07-21 |
| JP2022517984A (ja) | 2022-03-11 |
| BR112021013730A2 (pt) | 2021-09-21 |
| EP3909957A1 (fr) | 2021-11-17 |
| KR102650441B1 (ko) | 2024-03-21 |
| WO2020143798A1 (fr) | 2020-07-16 |
| MX2021008386A (es) | 2021-11-17 |
| CN113286798B (zh) | 2022-08-02 |
| AU2020205923A1 (en) | 2021-08-26 |
| CN113286798A (zh) | 2021-08-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3472362C0 (fr) | Inhibiteurs papd7 et papd5 pour traiter une infection par l'hépatite b | |
| EP3653630A4 (fr) | Composé thiamidinoamide-arylamide endocyclique et son utilisation dans le traitement de l'hépatite b | |
| ZA202106304B (en) | Heterocyclic compound and use thereof | |
| IL283525A (en) | Cyclic pentateine derivatives and their uses | |
| IL274040A (en) | Methods for treating hepatitis B infection | |
| ZA202105438B (en) | Internal cyclic sulphiamidine amide-aryl amide compound and use thereof for treating hepatitis b | |
| IL284116A (en) | Heteroaryldihydropyrimidine history and methods of treating hepatitis B infections | |
| PT3656782T (pt) | Composto amida peptídica e o seu método de preparação e utilização médica | |
| ZA202004548B (en) | Nitrogenated heterocyclic amide compound, and use thereof for medical purposes | |
| IL288082A (en) | Amide compounds and their method of preparation and their use | |
| EP4006024A4 (fr) | Composé amide hétérocyclique, son procédé de préparation et son utilisation | |
| EP3965832A4 (fr) | Compositions et méthodes de traitement de l'hépatite b | |
| GB2576890B (en) | Heating of an exhaust after-treatment component | |
| IL276912A (en) | Heterocyclic compound and its use | |
| IL267937A (en) | Amide compounds and their use | |
| SG11202011170YA (en) | Antibodies against lif and dosage forms thereof | |
| EP4069369A4 (fr) | Composés cycliques et leurs procédés d'utilisation | |
| EP3978076A4 (fr) | Composés d'amide cyclique pour le traitement de la rage et méthode associée | |
| GB202204938D0 (en) | Compounds comprising curcmin and basic amino acids | |
| GB201916573D0 (en) | Formula and process | |
| GB2570667B (en) | Adjustable mounting for exhaust treatment component | |
| EP4126844A4 (fr) | Composés amides et leurs utilisations | |
| IL275991A (en) | A cyclic amine derivative and its medicinal use | |
| EP4077305A4 (fr) | Dérivés d'hétéroaryldihydropyrimidine et procédés de traitement d'infections par le virus de l'hépatite b | |
| GB2554479B (en) | Electro-physical apparatus for the activation of nitrogen contained in engines at internal combustion emissions |