SG11202106121SA - Asymmetric rhodamine dye and use thereof in biological assays - Google Patents
Asymmetric rhodamine dye and use thereof in biological assaysInfo
- Publication number
- SG11202106121SA SG11202106121SA SG11202106121SA SG11202106121SA SG11202106121SA SG 11202106121S A SG11202106121S A SG 11202106121SA SG 11202106121S A SG11202106121S A SG 11202106121SA SG 11202106121S A SG11202106121S A SG 11202106121SA SG 11202106121S A SG11202106121S A SG 11202106121SA
- Authority
- SG
- Singapore
- Prior art keywords
- biological assays
- rhodamine dye
- asymmetric rhodamine
- asymmetric
- dye
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B11/00—Diaryl- or thriarylmethane dyes
- C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
- C09B11/10—Amino derivatives of triarylmethanes
- C09B11/24—Phthaleins containing amino groups ; Phthalanes; Fluoranes; Phthalides; Rhodamine dyes; Phthaleins having heterocyclic aryl rings; Lactone or lactame forms of triarylmethane dyes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862782445P | 2018-12-20 | 2018-12-20 | |
| PCT/US2019/068111 WO2020132607A1 (en) | 2018-12-20 | 2019-12-20 | Asymmetric rhodamine dye and use thereof in biological assays |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202106121SA true SG11202106121SA (en) | 2021-07-29 |
Family
ID=69191268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202106121SA SG11202106121SA (en) | 2018-12-20 | 2019-12-20 | Asymmetric rhodamine dye and use thereof in biological assays |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220380845A1 (ko) |
| EP (1) | EP3898841A1 (ko) |
| JP (1) | JP2022515153A (ko) |
| KR (1) | KR20210104125A (ko) |
| CN (1) | CN113195639A (ko) |
| AU (1) | AU2019404556A1 (ko) |
| BR (1) | BR112021012154A2 (ko) |
| CA (1) | CA3124361A1 (ko) |
| MX (1) | MX2021007492A (ko) |
| SG (1) | SG11202106121SA (ko) |
| WO (1) | WO2020132607A1 (ko) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022020723A1 (en) | 2020-07-23 | 2022-01-27 | Life Technologies Corporation | Energy transfer dye conjugates for use in biological assays |
| KR20230056685A (ko) | 2020-07-23 | 2023-04-27 | 라이프 테크놀로지스 코포레이션 | 염료를 사용한 생물학적 분석을 위한 조성물, 시스템 및 방법 |
| EP4204398A2 (en) * | 2020-08-28 | 2023-07-05 | Ventana Medical Systems, Inc. | Conjugates including a detectable moiety |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US162A (en) | 1837-04-17 | Island | ||
| US5847A (en) | 1848-10-10 | Wheel for spinning | ||
| US4481136A (en) | 1979-09-07 | 1984-11-06 | Syva Company | Alkyl substituted fluorescent compounds and conjugates |
| DE3071373D1 (en) | 1980-10-27 | 1986-03-06 | Syva Co | Novel ether substituted fluorescein compounds as fluorescers and quenchers |
| US4439356A (en) | 1981-03-03 | 1984-03-27 | Syva Company | Unsymmetrical fluorescein derivatives |
| US4622400A (en) | 1983-12-29 | 1986-11-11 | The United States Of America As Represented By The United States Department Of Energy | Preparation of certain m-aminophenols and the use thereof for preparation of laser dyes |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5151507A (en) | 1986-07-02 | 1992-09-29 | E. I. Du Pont De Nemours And Company | Alkynylamino-nucleotides |
| US5231191A (en) | 1987-12-24 | 1993-07-27 | Applied Biosystems, Inc. | Rhodamine phosphoramidite compounds |
| US5066580A (en) | 1988-08-31 | 1991-11-19 | Becton Dickinson And Company | Xanthene dyes that emit to the red of fluorescein |
| US5366860A (en) | 1989-09-29 | 1994-11-22 | Applied Biosystems, Inc. | Spectrally resolvable rhodamine dyes for nucleic acid sequence determination |
| US5188934A (en) | 1989-11-14 | 1993-02-23 | Applied Biosystems, Inc. | 4,7-dichlorofluorescein dyes as molecular probes |
| US5227487A (en) | 1990-04-16 | 1993-07-13 | Molecular Probes, Inc. | Certain tricyclic and pentacyclic-hetero nitrogen rhodol dyes |
| US5750409A (en) | 1991-11-18 | 1998-05-12 | Boehringer Mannheim Gmbh | Pentacyclic compounds and their use as absorption or fluorescent dyes |
| US5599666A (en) | 1994-03-28 | 1997-02-04 | Promega Corporation | Allelic ladders for short tandem repeat loci |
| US7008771B1 (en) | 1994-09-30 | 2006-03-07 | Promega Corporation | Multiplex amplification of short tandem repeat loci |
| US5654441A (en) | 1995-09-14 | 1997-08-05 | Uniroyal Chemical Ltd./Ltee | Synthesis of 1,3-oxathiolane sulfoxide compounds |
| US6020481A (en) | 1996-04-01 | 2000-02-01 | The Perkin-Elmer Corporation | Asymmetric benzoxanthene dyes |
| US5863727A (en) | 1996-05-03 | 1999-01-26 | The Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
| US5945526A (en) | 1996-05-03 | 1999-08-31 | Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
| US5847162A (en) | 1996-06-27 | 1998-12-08 | The Perkin Elmer Corporation | 4, 7-Dichlororhodamine dyes |
| US5800996A (en) | 1996-05-03 | 1998-09-01 | The Perkin Elmer Corporation | Energy transfer dyes with enchanced fluorescence |
| US6080852A (en) | 1996-06-27 | 2000-06-27 | The Perkin-Elmer Corporation | 4,7-dichlororhodamine dyes |
| US6017712A (en) | 1996-06-27 | 2000-01-25 | Lee; Linda | 4,7-dichlororhodamine dyes |
| US5821356A (en) | 1996-08-12 | 1998-10-13 | The Perkin Elmer Corporation | Propargylethoxyamino nucleotides |
| US6130101A (en) * | 1997-09-23 | 2000-10-10 | Molecular Probes, Inc. | Sulfonated xanthene derivatives |
| US6008379A (en) | 1997-10-01 | 1999-12-28 | The Perkin-Elmer Corporation | Aromatic-substituted xanthene dyes |
| US5936087A (en) | 1997-11-25 | 1999-08-10 | The Perkin-Elmer Corporation | Dibenzorhodamine dyes |
| US5948648A (en) | 1998-05-29 | 1999-09-07 | Khan; Shaheer H. | Nucleotide compounds including a rigid linker |
| DE19824535A1 (de) | 1998-06-03 | 1999-12-09 | Roche Diagnostics Gmbh | Neue Rhodamin-Derivate und deren Verwendung |
| US6248884B1 (en) | 1999-06-03 | 2001-06-19 | The Perkin-Elmer Corporation | Extended rhodamine compounds useful as fluorescent labels |
| US6358684B1 (en) | 1999-08-27 | 2002-03-19 | Pe Corporation | UV excitable fluorescent energy transfer dyes |
| US6221604B1 (en) | 2000-02-07 | 2001-04-24 | Pe Corporation | Electron-deficient nitrogen heterocycle-substituted fluorescein dyes |
| EP1317464B1 (en) | 2000-10-11 | 2009-05-13 | Applera Corporation | Fluorescent nucleobase conjugates having anionic linkers |
| US6780588B2 (en) | 2001-05-07 | 2004-08-24 | Applera Corporation | Methods for the reduction of stutter in microsatellite amplification |
| EP2640848A1 (en) | 2010-11-15 | 2013-09-25 | Life Technologies Corporation | Methods and kits for multiplex amplification of short tandem repeat loci |
-
2019
- 2019-12-20 WO PCT/US2019/068111 patent/WO2020132607A1/en unknown
- 2019-12-20 CN CN201980083475.2A patent/CN113195639A/zh active Pending
- 2019-12-20 BR BR112021012154-4A patent/BR112021012154A2/pt not_active Application Discontinuation
- 2019-12-20 US US17/299,671 patent/US20220380845A1/en active Pending
- 2019-12-20 SG SG11202106121SA patent/SG11202106121SA/en unknown
- 2019-12-20 MX MX2021007492A patent/MX2021007492A/es unknown
- 2019-12-20 EP EP19842699.1A patent/EP3898841A1/en active Pending
- 2019-12-20 KR KR1020217022566A patent/KR20210104125A/ko unknown
- 2019-12-20 AU AU2019404556A patent/AU2019404556A1/en active Pending
- 2019-12-20 JP JP2021535731A patent/JP2022515153A/ja active Pending
- 2019-12-20 CA CA3124361A patent/CA3124361A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20220380845A1 (en) | 2022-12-01 |
| WO2020132607A9 (en) | 2020-11-26 |
| JP2022515153A (ja) | 2022-02-17 |
| AU2019404556A1 (en) | 2021-06-24 |
| EP3898841A1 (en) | 2021-10-27 |
| KR20210104125A (ko) | 2021-08-24 |
| WO2020132607A1 (en) | 2020-06-25 |
| CN113195639A (zh) | 2021-07-30 |
| MX2021007492A (es) | 2021-10-13 |
| CA3124361A1 (en) | 2020-06-25 |
| BR112021012154A2 (pt) | 2021-09-08 |
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