SG10201912366YA - Anti-cd3 antibody and molecules comprising the antibody - Google Patents
Anti-cd3 antibody and molecules comprising the antibodyInfo
- Publication number
- SG10201912366YA SG10201912366YA SG10201912366YA SG10201912366YA SG10201912366YA SG 10201912366Y A SG10201912366Y A SG 10201912366YA SG 10201912366Y A SG10201912366Y A SG 10201912366YA SG 10201912366Y A SG10201912366Y A SG 10201912366YA SG 10201912366Y A SG10201912366Y A SG 10201912366YA
- Authority
- SG
- Singapore
- Prior art keywords
- antibody
- molecules
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
- C12N2015/8518—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic expressing industrially exogenous proteins, e.g. for pharmaceutical use, human insulin, blood factors, immunoglobulins, pseudoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2016249148 | 2016-12-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201912366YA true SG10201912366YA (en) | 2020-02-27 |
Family
ID=62627719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201912366YA SG10201912366YA (en) | 2016-12-22 | 2017-12-21 | Anti-cd3 antibody and molecules comprising the antibody |
Country Status (15)
Country | Link |
---|---|
US (2) | US11618785B2 (en) |
EP (1) | EP3561057A4 (en) |
JP (2) | JP7202185B2 (en) |
KR (1) | KR20190121294A (en) |
CN (2) | CN118126180A (en) |
AU (1) | AU2017379382A1 (en) |
BR (1) | BR112019012901A2 (en) |
CA (1) | CA3048174A1 (en) |
CO (1) | CO2019007823A2 (en) |
IL (2) | IL311136A (en) |
MX (1) | MX2019007347A (en) |
PH (1) | PH12019501387A1 (en) |
SG (1) | SG10201912366YA (en) |
TW (1) | TW201829467A (en) |
WO (1) | WO2018117237A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG10201912366YA (en) | 2016-12-22 | 2020-02-27 | Daiichi Sankyo Co Ltd | Anti-cd3 antibody and molecules comprising the antibody |
WO2019244107A1 (en) * | 2018-06-21 | 2019-12-26 | Daiichi Sankyo Company, Limited | Compositions including cd3 antigen binding fragments and uses thereof |
MX2021014973A (en) * | 2019-06-07 | 2022-04-18 | Adimab Llc | High affinity anti-cd3 antibodies, and methods for their generation and use. |
EP4144370A4 (en) * | 2020-03-30 | 2024-05-15 | Univ Mie | Bispecific antibody |
CN114656562B (en) * | 2020-12-23 | 2023-11-03 | 北京天广实生物技术股份有限公司 | Antibodies that bind human and monkey CD3 and uses thereof |
AU2022248779A1 (en) | 2021-03-29 | 2023-09-28 | Daiichi Sankyo Company, Limited | Stable multispecific molecule and use thereof |
WO2023061419A1 (en) * | 2021-10-12 | 2023-04-20 | Concept To Medicine Biotech Co., Ltd. | Anti-cd3 antibodies with cross-reactivity to human and cynomolgus proteins |
WO2023169419A1 (en) * | 2022-03-09 | 2023-09-14 | Antengene (Hangzhou) Biologics Co., Ltd. | Novel anti-cd3 antibodies and uses thereof |
WO2023183766A1 (en) * | 2022-03-20 | 2023-09-28 | Abcellera Biologics Inc. | Anti-cd3 antibodies and t-cell engagers and methods of use |
WO2023178645A1 (en) * | 2022-03-25 | 2023-09-28 | 嘉和生物药业有限公司 | Cd3-targeting antibody and use thereof |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
ES2139598T3 (en) | 1990-07-10 | 2000-02-16 | Medical Res Council | PROCEDURES FOR THE PRODUCTION OF SPECIFIC UNION COUPLE MEMBERS. |
GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
DE69229477T2 (en) | 1991-09-23 | 1999-12-09 | Cambridge Antibody Tech | Methods for the production of humanized antibodies |
US5885793A (en) | 1991-12-02 | 1999-03-23 | Medical Research Council | Production of anti-self antibodies from antibody segment repertoires and displayed on phage |
DE69333823T2 (en) | 1992-03-24 | 2006-05-04 | Cambridge Antibody Technology Ltd., Melbourn | METHOD FOR PRODUCING MEMBERS OF SPECIFIC BINDING SAVINGS |
GB9313509D0 (en) | 1993-06-30 | 1993-08-11 | Medical Res Council | Chemisynthetic libraries |
CA2177367A1 (en) | 1993-12-03 | 1995-06-08 | Andrew David Griffiths | Recombinant binding proteins and peptides |
US6214388B1 (en) | 1994-11-09 | 2001-04-10 | The Regents Of The University Of California | Immunoliposomes that optimize internalization into target cells |
US6972323B1 (en) | 1997-04-01 | 2005-12-06 | Sankyo Company, Limited | Anti-Fas antibodies |
ES2434961T5 (en) | 1998-04-20 | 2018-01-18 | Roche Glycart Ag | Antibody glycosylation engineering to improve antibody-dependent cell cytotoxicity |
DE19819846B4 (en) | 1998-05-05 | 2016-11-24 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Multivalent antibody constructs |
EP3031917A1 (en) | 1999-04-09 | 2016-06-15 | Kyowa Hakko Kirin Co., Ltd. | Method for controlling the activity of immunologically functional molecule |
JP3871503B2 (en) | 1999-08-30 | 2007-01-24 | 日本たばこ産業株式会社 | Immune disease treatment |
AU2001247616B2 (en) | 2000-04-11 | 2007-06-14 | Genentech, Inc. | Multivalent antibodies and uses therefor |
CN103333860B (en) | 2000-10-06 | 2015-07-08 | 协和发酵麒麟株式会社 | Cells producing antibody compositions |
EP1762617A1 (en) | 2003-01-07 | 2007-03-14 | Symphogen A/S | Method for manufacturing recombinant polyclonal proteins |
US7612181B2 (en) | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
EP1940881B1 (en) | 2005-10-11 | 2016-11-30 | Amgen Research (Munich) GmbH | Compositions comprising cross-species-specific antibodies and uses thereof |
JP5082104B2 (en) | 2006-03-23 | 2012-11-28 | 国立大学法人東北大学 | Highly functional bispecific antibody |
EP4059964A1 (en) | 2007-04-03 | 2022-09-21 | Amgen Research (Munich) GmbH | Cross-species-specific binding domain |
ES2695047T3 (en) | 2007-04-03 | 2018-12-28 | Amgen Research (Munich) Gmbh | Domain of specific union between species |
EP3375790A1 (en) * | 2008-10-01 | 2018-09-19 | Amgen Research (Munich) GmbH | Cross-species-specific single domain bispecific single chain antibody |
EP2270053A1 (en) | 2009-05-11 | 2011-01-05 | U3 Pharma GmbH | Humanized AXL antibodies |
SG10201703425RA (en) | 2011-05-21 | 2017-05-30 | Macrogenics Inc | Cd3-binding molecules capable of binding to human and non-human cd3 |
JP6280031B2 (en) | 2012-03-29 | 2018-02-14 | 中外製薬株式会社 | Anti-LAMP5 antibody and use thereof |
EP2839842A1 (en) | 2013-08-23 | 2015-02-25 | MacroGenics, Inc. | Bi-specific monovalent diabodies that are capable of binding CD123 and CD3 and uses thereof |
CN105940107B (en) | 2013-11-11 | 2021-06-15 | 中外制药株式会社 | Antigen binding molecules comprising altered antibody variable regions |
AU2015266077A1 (en) * | 2014-05-28 | 2016-09-29 | F. Hoffmann-La Roche Ag | Antibodies binding to human and cynomolgus CD3 epsilon |
US11154615B2 (en) * | 2014-11-11 | 2021-10-26 | Chugai Seiyaku Kabushiki Kaisha | Library of antigen-binding molecules including modified antibody variable region |
CN114230667A (en) * | 2015-01-23 | 2022-03-25 | 赛诺菲 | anti-CD 3 antibodies, anti-CD 123 antibodies, and bispecific antibodies that specifically bind to CD3 and/or CD123 |
SG10201912366YA (en) | 2016-12-22 | 2020-02-27 | Daiichi Sankyo Co Ltd | Anti-cd3 antibody and molecules comprising the antibody |
-
2017
- 2017-12-21 SG SG10201912366YA patent/SG10201912366YA/en unknown
- 2017-12-21 CN CN202311689828.8A patent/CN118126180A/en active Pending
- 2017-12-21 CN CN201780079717.1A patent/CN110431231B/en active Active
- 2017-12-21 EP EP17884717.4A patent/EP3561057A4/en active Pending
- 2017-12-21 IL IL311136A patent/IL311136A/en unknown
- 2017-12-21 JP JP2018558078A patent/JP7202185B2/en active Active
- 2017-12-21 WO PCT/JP2017/046006 patent/WO2018117237A1/en active Application Filing
- 2017-12-21 CA CA3048174A patent/CA3048174A1/en active Pending
- 2017-12-21 IL IL267567A patent/IL267567B1/en unknown
- 2017-12-21 MX MX2019007347A patent/MX2019007347A/en unknown
- 2017-12-21 AU AU2017379382A patent/AU2017379382A1/en active Pending
- 2017-12-21 KR KR1020197021178A patent/KR20190121294A/en active IP Right Grant
- 2017-12-21 BR BR112019012901-4A patent/BR112019012901A2/en unknown
- 2017-12-21 US US16/472,346 patent/US11618785B2/en active Active
- 2017-12-22 TW TW106145218A patent/TW201829467A/en unknown
-
2019
- 2019-06-18 PH PH12019501387A patent/PH12019501387A1/en unknown
- 2019-07-19 CO CONC2019/0007823A patent/CO2019007823A2/en unknown
-
2022
- 2022-12-23 JP JP2022206884A patent/JP7478222B2/en active Active
-
2023
- 2023-04-03 US US18/194,987 patent/US20230287119A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
PH12019501387A1 (en) | 2020-02-10 |
EP3561057A1 (en) | 2019-10-30 |
US11618785B2 (en) | 2023-04-04 |
US20190359712A1 (en) | 2019-11-28 |
RU2019122411A3 (en) | 2021-03-05 |
CN110431231B (en) | 2024-01-02 |
MX2019007347A (en) | 2019-12-05 |
BR112019012901A2 (en) | 2020-01-07 |
JP2023027374A (en) | 2023-03-01 |
CN118126180A (en) | 2024-06-04 |
TW201829467A (en) | 2018-08-16 |
JPWO2018117237A1 (en) | 2019-10-31 |
JP7202185B2 (en) | 2023-01-11 |
RU2019122411A (en) | 2021-01-25 |
CO2019007823A2 (en) | 2019-10-09 |
IL267567A (en) | 2024-04-01 |
AU2017379382A1 (en) | 2019-07-11 |
IL267567B1 (en) | 2024-04-01 |
KR20190121294A (en) | 2019-10-25 |
IL311136A (en) | 2024-04-01 |
EP3561057A4 (en) | 2020-09-16 |
CA3048174A1 (en) | 2018-06-28 |
CN110431231A (en) | 2019-11-08 |
JP7478222B2 (en) | 2024-05-02 |
US20230287119A1 (en) | 2023-09-14 |
WO2018117237A1 (en) | 2018-06-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA201905905B (en) | Anti-gprc5d antibody and molecule comprising the antibody | |
IL268206A (en) | Bcma-targeting antibody and use thereof | |
IL267942B (en) | Anti-cd73 antibodies and uses thereof | |
IL264011A (en) | Antibodies against tim3 and uses thereof | |
SG10201912199XA (en) | Anti-tim-3 antibodies and use thereof | |
IL262095A (en) | Anti-pacap antibodies and uses thereof | |
IL268734A (en) | Anti-lag-3 antibodies and uses thereof | |
IL268700A (en) | Anti-phf-tau antibodies and uses thereof | |
EP3541840C0 (en) | Anti-hla-g antibodies and use thereof | |
IL271477A (en) | Anti-cd166 antibodies and uses thereof | |
SG10201912366YA (en) | Anti-cd3 antibody and molecules comprising the antibody | |
IL263273A (en) | Anti-gitr antibodies and uses thereof | |
ZA201901935B (en) | Anti-il-33 antibodies and uses thereof | |
IL269134A (en) | Anti-par2 antibodies and uses thereof | |
HK1248721A1 (en) | Antibody molecules and uses thereof | |
IL262782B1 (en) | Tl1a antibodies and uses thereof | |
IL263242A (en) | Cytosol-penetrating antibody and use thereof | |
ZA201807132B (en) | Humanized anti-basigin antibodies and the use thereof | |
IL272476A (en) | Anti-apelin antibodies and uses thereof | |
IL266049A (en) | Anti-o1 antibodies and uses thereof | |
IL273157A (en) | Axl-specific antibodies and uses thereof | |
IL271398A (en) | Anti-l1-cam antibodies and uses thereof | |
AU2017271189A1 (en) | Cytosol-penetrating antibody and use thereof | |
IL266082A (en) | Anti-chikv antibodies and uses thereof | |
IL264417A (en) | Anti-o2 antibodies and uses thereof |