SG11202105772SA - Modulators of trex1 - Google Patents
Modulators of trex1Info
- Publication number
- SG11202105772SA SG11202105772SA SG11202105772SA SG11202105772SA SG11202105772SA SG 11202105772S A SG11202105772S A SG 11202105772SA SG 11202105772S A SG11202105772S A SG 11202105772SA SG 11202105772S A SG11202105772S A SG 11202105772SA SG 11202105772S A SG11202105772S A SG 11202105772SA
- Authority
- SG
- Singapore
- Prior art keywords
- trex1
- modulators
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862776031P | 2018-12-06 | 2018-12-06 | |
| PCT/US2019/064825 WO2020118133A1 (en) | 2018-12-06 | 2019-12-06 | Modulators of trex1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202105772SA true SG11202105772SA (en) | 2021-06-29 |
Family
ID=69024702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202105772SA SG11202105772SA (en) | 2018-12-06 | 2019-12-06 | Modulators of trex1 |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US20220017502A1 (es) |
| EP (1) | EP3891145B1 (es) |
| JP (1) | JP7471297B2 (es) |
| KR (1) | KR20210102310A (es) |
| CN (1) | CN113396149A (es) |
| AU (1) | AU2019395005A1 (es) |
| BR (1) | BR112021010919A2 (es) |
| CA (1) | CA3122093A1 (es) |
| CL (1) | CL2021001461A1 (es) |
| CO (1) | CO2021008816A2 (es) |
| CY (1) | CY1126082T1 (es) |
| DK (1) | DK3891145T3 (es) |
| EA (1) | EA202191519A1 (es) |
| ES (1) | ES2949999T3 (es) |
| FI (1) | FI3891145T3 (es) |
| HR (1) | HRP20230701T1 (es) |
| HU (1) | HUE062866T2 (es) |
| IL (1) | IL283672A (es) |
| LT (1) | LT3891145T (es) |
| MA (1) | MA54386B1 (es) |
| MX (1) | MX2021006695A (es) |
| PE (1) | PE20212070A1 (es) |
| PL (1) | PL3891145T3 (es) |
| PT (1) | PT3891145T (es) |
| RS (1) | RS64336B1 (es) |
| SG (1) | SG11202105772SA (es) |
| SI (1) | SI3891145T1 (es) |
| WO (1) | WO2020118133A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020316056A1 (en) * | 2019-07-23 | 2022-02-03 | Constellation Pharmaceuticals, Inc. | Modulators of TREX1 |
| WO2022031640A1 (en) * | 2020-08-04 | 2022-02-10 | Wake Forest University Health Sciences | Trex1 inhibitors and uses thereof |
| AU2022264711A1 (en) * | 2021-04-26 | 2023-11-09 | Constellation Pharmaceuticals, Inc. | Modulators of trex1 |
| CR20230569A (es) * | 2021-05-05 | 2024-01-22 | Constellation Pharmaceuticals Inc | Moduladores de trex1 |
| WO2023137030A1 (en) * | 2022-01-11 | 2023-07-20 | Constellation Pharmaceuticals, Inc. | Modulators of trex1 |
| WO2023156386A2 (en) * | 2022-02-16 | 2023-08-24 | Duke Street Bio Limited | Pharmaceutical compound |
| WO2023250439A1 (en) * | 2022-06-22 | 2023-12-28 | Tempest Therapeutics, Inc. | Trex1 inhibitors and uses thereof |
| WO2024061300A1 (en) * | 2022-09-22 | 2024-03-28 | Insilico Medicine Ip Limited | Inhibitors of trex1 and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007056124A2 (en) * | 2005-11-04 | 2007-05-18 | Hydra Biosciences, Inc. | Compounds for modulating trpv3 function |
| WO2009106561A1 (en) * | 2008-02-27 | 2009-09-03 | Biovitrum Ab (Publ) | Pyrazine compounds for treating gpr119 related disorders |
| ES2409262T3 (es) * | 2008-06-02 | 2013-06-26 | Janssen Pharmaceutica, N.V. | Antagonistas de TRPA1 de 3,4-dihidropirimidina |
| BR112012007349A2 (pt) * | 2009-10-02 | 2019-09-24 | Sanofi Sa | uso de composto com atividade inibidora de sglt-1/sglt-2 para produção de medicamentos para tratamento de doenças ósseas. |
| WO2011107494A1 (de) * | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| AR085436A1 (es) * | 2011-03-17 | 2013-10-02 | Bristol Myers Squibb Co | Derivados de pirrolopiridazina inhibidores de jak3, composiciones farmaceuticas que los contienen y su uso para tratar enfermedades inflamatorias y autoinmunes |
-
2019
- 2019-12-06 BR BR112021010919-6A patent/BR112021010919A2/pt unknown
- 2019-12-06 LT LTEPPCT/US2019/064825T patent/LT3891145T/lt unknown
- 2019-12-06 PL PL19828476.2T patent/PL3891145T3/pl unknown
- 2019-12-06 CA CA3122093A patent/CA3122093A1/en active Pending
- 2019-12-06 EA EA202191519A patent/EA202191519A1/ru unknown
- 2019-12-06 EP EP19828476.2A patent/EP3891145B1/en active Active
- 2019-12-06 DK DK19828476.2T patent/DK3891145T3/da active
- 2019-12-06 PE PE2021000822A patent/PE20212070A1/es unknown
- 2019-12-06 WO PCT/US2019/064825 patent/WO2020118133A1/en unknown
- 2019-12-06 US US17/311,526 patent/US20220017502A1/en active Pending
- 2019-12-06 RS RS20230531A patent/RS64336B1/sr unknown
- 2019-12-06 AU AU2019395005A patent/AU2019395005A1/en active Pending
- 2019-12-06 MA MA54386A patent/MA54386B1/fr unknown
- 2019-12-06 JP JP2021531909A patent/JP7471297B2/ja active Active
- 2019-12-06 FI FIEP19828476.2T patent/FI3891145T3/fi active
- 2019-12-06 SI SI201930577T patent/SI3891145T1/sl unknown
- 2019-12-06 KR KR1020217020940A patent/KR20210102310A/ko unknown
- 2019-12-06 MX MX2021006695A patent/MX2021006695A/es unknown
- 2019-12-06 HU HUE19828476A patent/HUE062866T2/hu unknown
- 2019-12-06 SG SG11202105772SA patent/SG11202105772SA/en unknown
- 2019-12-06 ES ES19828476T patent/ES2949999T3/es active Active
- 2019-12-06 PT PT198284762T patent/PT3891145T/pt unknown
- 2019-12-06 HR HRP20230701TT patent/HRP20230701T1/hr unknown
- 2019-12-06 CN CN201980091375.4A patent/CN113396149A/zh active Pending
-
2021
- 2021-06-03 IL IL283672A patent/IL283672A/en unknown
- 2021-06-03 CL CL2021001461A patent/CL2021001461A1/es unknown
- 2021-07-02 CO CONC2021/0008816A patent/CO2021008816A2/es unknown
-
2023
- 2023-07-11 CY CY20231100328T patent/CY1126082T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT3891145T (pt) | 2023-07-18 |
| DK3891145T3 (da) | 2023-07-24 |
| CA3122093A1 (en) | 2020-06-11 |
| WO2020118133A1 (en) | 2020-06-11 |
| CY1126082T1 (el) | 2023-11-15 |
| PL3891145T3 (pl) | 2023-08-07 |
| MA54386B1 (fr) | 2023-08-31 |
| MA54386A (fr) | 2021-10-13 |
| BR112021010919A2 (pt) | 2021-08-24 |
| EA202191519A1 (ru) | 2021-10-27 |
| EP3891145A1 (en) | 2021-10-13 |
| CN113396149A (zh) | 2021-09-14 |
| PE20212070A1 (es) | 2021-10-26 |
| CO2021008816A2 (es) | 2021-07-19 |
| IL283672A (en) | 2021-07-29 |
| MX2021006695A (es) | 2021-09-23 |
| HRP20230701T1 (hr) | 2023-10-13 |
| AU2019395005A1 (en) | 2021-06-17 |
| HUE062866T2 (hu) | 2023-12-28 |
| EP3891145B1 (en) | 2023-04-12 |
| RS64336B1 (sr) | 2023-08-31 |
| ES2949999T3 (es) | 2023-10-04 |
| JP2022510431A (ja) | 2022-01-26 |
| US20220017502A1 (en) | 2022-01-20 |
| LT3891145T (lt) | 2023-08-10 |
| FI3891145T3 (fi) | 2023-07-18 |
| KR20210102310A (ko) | 2021-08-19 |
| JP7471297B2 (ja) | 2024-04-19 |
| CL2021001461A1 (es) | 2021-12-17 |
| SI3891145T1 (sl) | 2023-11-30 |
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