SG11202104288PA - Dna methylation biomarkers for early detection of cervical cancer - Google Patents

Dna methylation biomarkers for early detection of cervical cancer

Info

Publication number
SG11202104288PA
SG11202104288PA SG11202104288PA SG11202104288PA SG11202104288PA SG 11202104288P A SG11202104288P A SG 11202104288PA SG 11202104288P A SG11202104288P A SG 11202104288PA SG 11202104288P A SG11202104288P A SG 11202104288PA SG 11202104288P A SG11202104288P A SG 11202104288PA
Authority
SG
Singapore
Prior art keywords
cervical cancer
dna methylation
early detection
methylation biomarkers
biomarkers
Prior art date
Application number
SG11202104288PA
Other languages
English (en)
Inventor
Moshe Szyf
David Cheishvili
Eduardo Franco
Mariam El-Zein
Original Assignee
Hkg Epitherapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hkg Epitherapeutics Ltd filed Critical Hkg Epitherapeutics Ltd
Publication of SG11202104288PA publication Critical patent/SG11202104288PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Medical Informatics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SG11202104288PA 2018-12-04 2020-02-04 Dna methylation biomarkers for early detection of cervical cancer SG11202104288PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862774994P 2018-12-04 2018-12-04
PCT/IB2020/050885 WO2020115728A2 (en) 2018-12-04 2020-02-04 Dna methylation biomarkers for early detection of cervical cancer

Publications (1)

Publication Number Publication Date
SG11202104288PA true SG11202104288PA (en) 2021-05-28

Family

ID=70975630

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202104288PA SG11202104288PA (en) 2018-12-04 2020-02-04 Dna methylation biomarkers for early detection of cervical cancer

Country Status (11)

Country Link
US (1) US20220073994A1 (ja)
EP (1) EP3891296A4 (ja)
JP (2) JP7489979B2 (ja)
KR (1) KR20210117262A (ja)
CN (1) CN113423843A (ja)
AU (1) AU2020203961A1 (ja)
BR (1) BR112021010640A2 (ja)
CA (1) CA3121886A1 (ja)
IL (1) IL283616A (ja)
SG (1) SG11202104288PA (ja)
WO (1) WO2020115728A2 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202009222D0 (en) * 2020-06-17 2020-07-29 Ucl Business Plc Methods for detecting and predicting cancer
GB202009217D0 (en) * 2020-06-17 2020-07-29 Ucl Business Ltd Methods for detecting and predicting breast cancer
MX2022016097A (es) * 2020-06-17 2023-04-20 Ucl Business Ltd Procedimientos para detectar y predecir neoplasia epitelial cervical de grado 3 (cin3) y/o cáncer.
GB202009220D0 (en) * 2020-06-17 2020-07-29 Ucl Business Ltd Methods for detecting and predicting cancer
IL299142A (en) * 2020-06-17 2023-02-01 Ucl Business Ltd Methods for the diagnosis and prognosis of cancer and/or CIN3
CN112048561B (zh) * 2020-09-18 2021-11-26 北京起源聚禾生物科技有限公司 用于宫颈高级别病变和宫颈癌早期检测的组合物及试剂盒
JP2024509851A (ja) * 2021-03-05 2024-03-05 マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチ 子宮頸癌の検出
CN113943817B (zh) * 2021-12-20 2022-04-19 北京迈基诺基因科技股份有限公司 宫颈癌癌化水平评估模型及构建方法
CN114214415A (zh) * 2021-12-29 2022-03-22 广州安必平医药科技股份有限公司 一种用于宫颈癌相关基因甲基化检测的引物探针组合及其应用
CN115612744A (zh) * 2022-12-14 2023-01-17 中国医学科学院肿瘤医院 人乳头瘤病毒分型及相关基因甲基化一体化检测模型及其构建方法
CN117265096A (zh) * 2023-09-07 2023-12-22 北京美康基因科学股份有限公司 用于宫颈高级别病变和宫颈癌早期检测的试剂盒

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10961590B2 (en) * 2015-09-17 2021-03-30 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Cancer detection methods
CN107541565B (zh) 2016-06-23 2021-07-06 首都医科大学附属北京佑安医院 宿主外周血单个核细胞和t细胞的癌症dna甲基化标志物
US20190345559A1 (en) 2016-06-23 2019-11-14 Moshe Szyf Dna methylation signatures of cancer in host peripheral blood mononuclear cells and t cells
BR112019018743A2 (pt) * 2017-03-10 2020-05-05 Self-Screen B.V. classificador de metilação para detecção de cânceres invasivos induzidos por hpv, cânceres ginecológicos e anogenitais não induzidos por hpv e suas lesões precursoras de alto grau

Also Published As

Publication number Publication date
JP7489979B2 (ja) 2024-05-24
WO2020115728A2 (en) 2020-06-11
AU2020203961A1 (en) 2021-06-17
BR112021010640A2 (pt) 2021-09-08
KR20210117262A (ko) 2021-09-28
CA3121886A1 (en) 2020-06-11
IL283616A (en) 2021-07-29
CN113423843A (zh) 2021-09-21
US20220073994A1 (en) 2022-03-10
JP2024056878A (ja) 2024-04-23
EP3891296A4 (en) 2022-11-16
EP3891296A2 (en) 2021-10-13
JP2022531637A (ja) 2022-07-08
WO2020115728A3 (en) 2020-09-24

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