SG11202101687TA - 2,6-diamino pyridine compounds - Google Patents

2,6-diamino pyridine compounds

Info

Publication number
SG11202101687TA
SG11202101687TA SG11202101687TA SG11202101687TA SG11202101687TA SG 11202101687T A SG11202101687T A SG 11202101687TA SG 11202101687T A SG11202101687T A SG 11202101687TA SG 11202101687T A SG11202101687T A SG 11202101687TA SG 11202101687T A SG11202101687T A SG 11202101687TA
Authority
SG
Singapore
Prior art keywords
pyridine compounds
diamino pyridine
diamino
compounds
pyridine
Prior art date
Application number
SG11202101687TA
Other languages
English (en)
Inventor
Timothy Barrett Durham
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SG11202101687TA publication Critical patent/SG11202101687TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG11202101687TA 2018-09-04 2019-08-29 2,6-diamino pyridine compounds SG11202101687TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862726520P 2018-09-04 2018-09-04
PCT/US2019/048788 WO2020051058A1 (en) 2018-09-04 2019-08-29 2,6-diamino pyridine compounds

Publications (1)

Publication Number Publication Date
SG11202101687TA true SG11202101687TA (en) 2021-03-30

Family

ID=67982138

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202101687TA SG11202101687TA (en) 2018-09-04 2019-08-29 2,6-diamino pyridine compounds

Country Status (27)

Country Link
US (1) US10781212B2 (ru)
EP (1) EP3846809B1 (ru)
JP (1) JP6813720B1 (ru)
KR (1) KR102365535B1 (ru)
CN (1) CN112601525B (ru)
AR (1) AR117640A1 (ru)
AU (1) AU2019334877B2 (ru)
BR (1) BR112021001881A2 (ru)
CA (1) CA3111725C (ru)
CL (1) CL2021000528A1 (ru)
CO (1) CO2021002768A2 (ru)
CR (1) CR20210085A (ru)
DO (1) DOP2021000027A (ru)
EA (1) EA202190302A1 (ru)
EC (1) ECSP21015267A (ru)
ES (1) ES2971802T3 (ru)
IL (1) IL280598B2 (ru)
JO (1) JOP20210039A1 (ru)
MA (1) MA53547A (ru)
MX (1) MX2021002472A (ru)
PE (1) PE20211595A1 (ru)
PH (1) PH12021550449A1 (ru)
SG (1) SG11202101687TA (ru)
TW (1) TWI714231B (ru)
UA (1) UA124917C2 (ru)
WO (1) WO2020051058A1 (ru)
ZA (1) ZA202100700B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI750685B (zh) * 2019-06-17 2021-12-21 美商美國禮來大藥廠 二取代吡唑化合物
TWI764467B (zh) * 2019-12-24 2022-05-11 大陸商南京明德新藥研發有限公司 具有khk抑制作用的化合物
CN111423420A (zh) * 2020-04-30 2020-07-17 广州博济医药生物技术股份有限公司 作为己酮糖激酶抑制剂的并环化合物
US20230079863A1 (en) 2021-03-29 2023-03-16 Gilead Sciences, Inc. Khk inhibitors
WO2023151473A1 (zh) * 2022-02-09 2023-08-17 上海研健新药研发有限公司 一种khk抑制剂,其制备方法和应用
WO2024121183A1 (en) * 2022-12-08 2024-06-13 Boehringer Ingelheim International Gmbh New cyanopyridine khk inhibitor compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2094709B1 (en) * 2006-09-20 2010-09-15 Eli Lilly And Company Thiazole pyrazolopyrimidines as crf1 receptor antagonists
AR099937A1 (es) * 2014-04-04 2016-08-31 Sanofi Sa Compuestos de isoindolinona como moduladores de gpr119 para el tratamiento de diabetes, obesidad, dislipidemia y trastornos relacionados
MY191956A (en) * 2014-05-15 2022-07-20 Array Biopharma Inc 1-((3s,4r)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1h-pyrazol-5-yl)urea as a trka kinase inhibitor
RS61896B1 (sr) * 2015-12-29 2021-06-30 Pfizer Supstituisani 3-azabiciklo[3.1.0]heksani kao inhibitori ketoheksokinaze

Also Published As

Publication number Publication date
EP3846809B1 (en) 2023-12-13
IL280598B1 (en) 2023-10-01
ES2971802T3 (es) 2024-06-07
CL2021000528A1 (es) 2021-07-30
EA202190302A1 (ru) 2021-06-10
IL280598B2 (en) 2024-02-01
AU2019334877B2 (en) 2022-07-28
WO2020051058A1 (en) 2020-03-12
US20200071331A1 (en) 2020-03-05
CA3111725C (en) 2022-12-13
JOP20210039A1 (ar) 2021-03-04
UA124917C2 (uk) 2021-12-08
TW202026289A (zh) 2020-07-16
CA3111725A1 (en) 2020-03-12
TWI714231B (zh) 2020-12-21
AU2019334877A1 (en) 2021-03-11
AR117640A1 (es) 2021-08-18
CR20210085A (es) 2021-04-29
KR102365535B1 (ko) 2022-02-23
IL280598A (en) 2021-03-25
ECSP21015267A (es) 2021-04-29
CN112601525A (zh) 2021-04-02
DOP2021000027A (es) 2021-03-15
JP2021506949A (ja) 2021-02-22
PH12021550449A1 (en) 2021-09-27
MA53547A (fr) 2022-04-27
EP3846809A1 (en) 2021-07-14
ZA202100700B (en) 2022-09-28
PE20211595A1 (es) 2021-08-18
JP6813720B1 (ja) 2021-01-13
CN112601525B (zh) 2023-11-10
KR20210034082A (ko) 2021-03-29
US10781212B2 (en) 2020-09-22
CO2021002768A2 (es) 2021-05-20
BR112021001881A2 (pt) 2021-04-27
MX2021002472A (es) 2021-04-29

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