MA53547A - Composés de 2,6-diamino pyridine - Google Patents

Composés de 2,6-diamino pyridine

Info

Publication number
MA53547A
MA53547A MA053547A MA53547A MA53547A MA 53547 A MA53547 A MA 53547A MA 053547 A MA053547 A MA 053547A MA 53547 A MA53547 A MA 53547A MA 53547 A MA53547 A MA 53547A
Authority
MA
Morocco
Prior art keywords
pyridine compounds
diamino pyridine
diamino
compounds
pyridine
Prior art date
Application number
MA053547A
Other languages
English (en)
Inventor
Timothy Barrett Durham
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MA53547A publication Critical patent/MA53547A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MA053547A 2018-09-04 2019-08-29 Composés de 2,6-diamino pyridine MA53547A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862726520P 2018-09-04 2018-09-04

Publications (1)

Publication Number Publication Date
MA53547A true MA53547A (fr) 2022-04-27

Family

ID=67982138

Family Applications (1)

Application Number Title Priority Date Filing Date
MA053547A MA53547A (fr) 2018-09-04 2019-08-29 Composés de 2,6-diamino pyridine

Country Status (27)

Country Link
US (1) US10781212B2 (fr)
EP (1) EP3846809B1 (fr)
JP (1) JP6813720B1 (fr)
KR (1) KR102365535B1 (fr)
CN (1) CN112601525B (fr)
AR (1) AR117640A1 (fr)
AU (1) AU2019334877B2 (fr)
BR (1) BR112021001881A2 (fr)
CA (1) CA3111725C (fr)
CL (1) CL2021000528A1 (fr)
CO (1) CO2021002768A2 (fr)
CR (1) CR20210085A (fr)
DO (1) DOP2021000027A (fr)
EA (1) EA202190302A1 (fr)
EC (1) ECSP21015267A (fr)
ES (1) ES2971802T3 (fr)
IL (1) IL280598B2 (fr)
JO (1) JOP20210039A1 (fr)
MA (1) MA53547A (fr)
MX (1) MX2021002472A (fr)
PE (1) PE20211595A1 (fr)
PH (1) PH12021550449A1 (fr)
SG (1) SG11202101687TA (fr)
TW (1) TWI714231B (fr)
UA (1) UA124917C2 (fr)
WO (1) WO2020051058A1 (fr)
ZA (1) ZA202100700B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI750685B (zh) * 2019-06-17 2021-12-21 美商美國禮來大藥廠 二取代吡唑化合物
TWI764467B (zh) * 2019-12-24 2022-05-11 大陸商南京明德新藥研發有限公司 具有khk抑制作用的化合物
CN111423420A (zh) * 2020-04-30 2020-07-17 广州博济医药生物技术股份有限公司 作为己酮糖激酶抑制剂的并环化合物
EP4313967A1 (fr) 2021-03-29 2024-02-07 Gilead Sciences, Inc. Inhibiteurs de khk
WO2023151473A1 (fr) * 2022-02-09 2023-08-17 上海研健新药研发有限公司 Inhibiteur de khk, son procédé de préparation et son utilisation
WO2024121183A1 (fr) * 2022-12-08 2024-06-13 Boehringer Ingelheim International Gmbh Nouveaux composés inhibiteurs de cyanopyridine khk

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101088239B1 (ko) * 2006-09-20 2011-11-30 일라이 릴리 앤드 캄파니 Crf1 수용체 길항제로서의 티아졸 피라졸로피리미딘
AR099937A1 (es) * 2014-04-04 2016-08-31 Sanofi Sa Compuestos de isoindolinona como moduladores de gpr119 para el tratamiento de diabetes, obesidad, dislipidemia y trastornos relacionados
MY191956A (en) * 2014-05-15 2022-07-20 Array Biopharma Inc 1-((3s,4r)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1h-pyrazol-5-yl)urea as a trka kinase inhibitor
MD3397631T2 (ro) * 2015-12-29 2021-08-31 Pfizer 3-Azabiciclo[3.1.0] hexani substituiţi drept inhibitori de cetohexokinază

Also Published As

Publication number Publication date
PH12021550449A1 (en) 2021-09-27
US10781212B2 (en) 2020-09-22
DOP2021000027A (es) 2021-03-15
CO2021002768A2 (es) 2021-05-20
BR112021001881A2 (pt) 2021-04-27
IL280598B1 (en) 2023-10-01
JP2021506949A (ja) 2021-02-22
KR20210034082A (ko) 2021-03-29
TW202026289A (zh) 2020-07-16
ZA202100700B (en) 2022-09-28
JP6813720B1 (ja) 2021-01-13
IL280598A (en) 2021-03-25
TWI714231B (zh) 2020-12-21
ECSP21015267A (es) 2021-04-29
CR20210085A (es) 2021-04-29
SG11202101687TA (en) 2021-03-30
US20200071331A1 (en) 2020-03-05
CN112601525B (zh) 2023-11-10
UA124917C2 (uk) 2021-12-08
MX2021002472A (es) 2021-04-29
AR117640A1 (es) 2021-08-18
CA3111725A1 (fr) 2020-03-12
IL280598B2 (en) 2024-02-01
CL2021000528A1 (es) 2021-07-30
EP3846809A1 (fr) 2021-07-14
ES2971802T3 (es) 2024-06-07
PE20211595A1 (es) 2021-08-18
EP3846809B1 (fr) 2023-12-13
AU2019334877B2 (en) 2022-07-28
CA3111725C (fr) 2022-12-13
AU2019334877A1 (en) 2021-03-11
EA202190302A1 (ru) 2021-06-10
CN112601525A (zh) 2021-04-02
WO2020051058A1 (fr) 2020-03-12
KR102365535B1 (ko) 2022-02-23
JOP20210039A1 (ar) 2021-03-04

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