SG11202012829RA - Acetyl-coa carboxylase2 antisense oligonucleotides - Google Patents

Acetyl-coa carboxylase2 antisense oligonucleotides

Info

Publication number
SG11202012829RA
SG11202012829RA SG11202012829RA SG11202012829RA SG11202012829RA SG 11202012829R A SG11202012829R A SG 11202012829RA SG 11202012829R A SG11202012829R A SG 11202012829RA SG 11202012829R A SG11202012829R A SG 11202012829RA SG 11202012829R A SG11202012829R A SG 11202012829RA
Authority
SG
Singapore
Prior art keywords
coa
acetyl
antisense oligonucleotides
antisense
oligonucleotides
Prior art date
Application number
SG11202012829RA
Other languages
English (en)
Inventor
Seon-Young Han
Kiho Sung
Myunghyo Hong
Dayoung Kang
Jeong-Seok Heo
Kang Won Jang
Original Assignee
Olipass Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olipass Corp filed Critical Olipass Corp
Publication of SG11202012829RA publication Critical patent/SG11202012829RA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C07K14/003Peptide-nucleic acids (PNAs)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/53Ligases (6)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/31Chemical structure of the backbone
    • C12N2310/318Chemical structure of the backbone where the PO2 is completely replaced, e.g. MMI or formacetal
    • C12N2310/3181Peptide nucleic acid, PNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y604/00Ligases forming carbon-carbon bonds (6.4)
    • C12Y604/01Ligases forming carbon-carbon bonds (6.4.1)
    • C12Y604/01002Acetyl-CoA carboxylase (6.4.1.2)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
SG11202012829RA 2018-08-14 2019-08-05 Acetyl-coa carboxylase2 antisense oligonucleotides SG11202012829RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020180095124A KR102304280B1 (ko) 2018-08-14 2018-08-14 아세틸코에이카복실라제2 안티센스 올리고뉴클레오티드
PCT/KR2019/009697 WO2020036353A1 (en) 2018-08-14 2019-08-05 Acetyl-coa carboxylase2 antisense oligonucleotides

Publications (1)

Publication Number Publication Date
SG11202012829RA true SG11202012829RA (en) 2021-02-25

Family

ID=69525636

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202012829RA SG11202012829RA (en) 2018-08-14 2019-08-05 Acetyl-coa carboxylase2 antisense oligonucleotides

Country Status (13)

Country Link
US (1) US11739124B2 (es)
EP (1) EP3837274A4 (es)
JP (2) JP2021534146A (es)
KR (1) KR102304280B1 (es)
CN (1) CN112566922B (es)
AR (1) AR115955A1 (es)
AU (1) AU2019320670B2 (es)
BR (1) BR112020026541A2 (es)
CA (1) CA3104658A1 (es)
MX (1) MX2021000998A (es)
SG (1) SG11202012829RA (es)
TW (1) TWI826490B (es)
WO (1) WO2020036353A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102304280B1 (ko) 2018-08-14 2021-09-23 올리패스 주식회사 아세틸코에이카복실라제2 안티센스 올리고뉴클레오티드

Family Cites Families (26)

* Cited by examiner, † Cited by third party
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US6133444A (en) 1993-12-22 2000-10-17 Perseptive Biosystems, Inc. Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions
US6617422B1 (en) 1997-05-23 2003-09-09 Peter Nielsen Peptide nucleic acid monomers and oligomers
US20030105044A1 (en) 2001-10-17 2003-06-05 Isis Pharmaceuticals Inc. Antisense modulation of matrix metalloproteinase 1 expression
US20040215006A1 (en) 2003-04-25 2004-10-28 Isis Pharmaceuticals Inc. Modulation of tyrosinase expression
GB0415196D0 (en) * 2004-07-07 2004-08-11 Astrazeneca Ab Polypeptide
US7211423B2 (en) * 2004-07-23 2007-05-01 Bristol-Myers Squibb Co. Acetyl CoA carboxylase 2 sequences and methods
AU2006235451A1 (en) * 2005-04-08 2006-10-19 Isis Pharmaceuticals, Inc. Compositions and their uses directed to acetyl-CoA carboxylases
BE1017127A6 (nl) 2006-03-24 2008-03-04 Hyfte Luc J R Van Scharnierende bevestiging van een paddelroerwerk.
JP2010075639A (ja) * 2007-10-19 2010-04-08 Shiseido Co Ltd 顔面及び頸部の皮膚状態を改善する美容方法及び装置
KR20090098710A (ko) 2008-03-14 2009-09-17 주식회사 씨티아이바이오 세포투과성과 핵산 결합력이 좋은 펩타이드 핵산 유도체
KR20110112381A (ko) 2008-12-31 2011-10-12 레반스 테라퓨틱스, 아이엔씨. 색소 과다 침착의 치료용 조성물 및 치료 방법
WO2010123983A1 (en) 2009-04-21 2010-10-28 Yale University Compostions and methods for targeted gene therapy
KR20120073536A (ko) * 2010-12-27 2012-07-05 주식회사 파나진 다중전하를 갖는 pna
WO2013112548A1 (en) 2012-01-23 2013-08-01 University Of South Florida Gamma-aapeptides with potent and broad-spectrum antimicrobial activity
US20140314697A1 (en) 2013-04-18 2014-10-23 Corum Inc. Method for Inhibiting Inflammation and Reducing Melanophilin Expression with Glycine Derivatives And the Composition Thereof
KR101809209B1 (ko) * 2016-05-31 2017-12-15 주식회사 올리패스코스메슈티컬즈 두피의 건강 개선을 위한 화장료 조성물 및 이의 제조방법
US20190345202A1 (en) * 2016-08-08 2019-11-14 Olipass Corporation Androgen receptor antisense oligonucleotides
EP3512870B1 (en) 2016-09-16 2022-08-03 Olipass Corporation Scn9a antisense oligonucleotides
RU2753517C2 (ru) 2016-10-11 2021-08-17 Олипасс Корпорейшн Антисмысловые олигонуклеотиды к hif-1-альфа
US20190337987A1 (en) * 2016-12-30 2019-11-07 Olipass Corporation Exon skipping by peptide nucleic acid derivatives
JP7503903B2 (ja) * 2017-01-06 2024-06-21 オリパス コーポレーション Snap25アンチセンスオリゴヌクレオチド
RU2762293C2 (ru) 2017-01-24 2021-12-17 Олипасс Корпорейшн Антисмысловое для scn9a обезболивающее средство
WO2019022434A1 (en) 2017-07-24 2019-01-31 Olipass Corporation ANTISENSE OLIGONUCLEOTIDES OF TYROSINASE
TWI832851B (zh) 2018-05-18 2024-02-21 韓商奧利通公司 基質金屬蛋白酶-1之反義寡核苷酸
KR102304280B1 (ko) 2018-08-14 2021-09-23 올리패스 주식회사 아세틸코에이카복실라제2 안티센스 올리고뉴클레오티드
JP2022541896A (ja) 2019-07-18 2022-09-28 オリパス コーポレーション メラノフィリンアンチセンスオリゴヌクレオチド

Also Published As

Publication number Publication date
AU2019320670A1 (en) 2021-02-11
US11739124B2 (en) 2023-08-29
WO2020036353A1 (en) 2020-02-20
EP3837274A1 (en) 2021-06-23
TW202022115A (zh) 2020-06-16
CN112566922A (zh) 2021-03-26
EP3837274A4 (en) 2022-05-18
CN112566922B (zh) 2024-09-13
JP2021534146A (ja) 2021-12-09
AU2019320670B2 (en) 2024-04-11
KR102304280B1 (ko) 2021-09-23
MX2021000998A (es) 2021-06-23
KR20200019509A (ko) 2020-02-24
TWI826490B (zh) 2023-12-21
AR115955A1 (es) 2021-03-17
JP2024038106A (ja) 2024-03-19
US20210363190A1 (en) 2021-11-25
BR112020026541A2 (pt) 2021-04-06
CA3104658A1 (en) 2020-02-20

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