SG11202009696WA - Machine learning implementation for multi-analyte assay of biological samples - Google Patents

Machine learning implementation for multi-analyte assay of biological samples

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Publication number
SG11202009696WA
SG11202009696WA SG11202009696WA SG11202009696WA SG11202009696WA SG 11202009696W A SG11202009696W A SG 11202009696WA SG 11202009696W A SG11202009696W A SG 11202009696WA SG 11202009696W A SG11202009696W A SG 11202009696WA SG 11202009696W A SG11202009696W A SG 11202009696WA
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SG
Singapore
Prior art keywords
machine learning
biological samples
analyte assay
learning implementation
implementation
Prior art date
Application number
SG11202009696WA
Other languages
English (en)
Inventor
Adam Drake
Daniel Delubac
Katherine Niehaus
Eric Ariazi
Imran Haque
Tzu-Yu Liu
Nathan Wan
Ajay Kannan
Brandon White
Original Assignee
Freenome Holdings Inc
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Application filed by Freenome Holdings Inc filed Critical Freenome Holdings Inc
Publication of SG11202009696WA publication Critical patent/SG11202009696WA/en

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    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N20/00Machine learning
    • G06N20/10Machine learning using kernel methods, e.g. support vector machines [SVM]
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/02Neural networks
    • G06N3/08Learning methods
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20Supervised data analysis
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00Pattern recognition
    • G06F18/20Analysing
    • G06F18/24Classification techniques
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N20/00Machine learning
    • G06N20/20Ensemble learning
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N7/00Computing arrangements based on specific mathematical models
    • G06N7/01Probabilistic graphical models, e.g. probabilistic networks
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Data Mining & Analysis (AREA)
  • Theoretical Computer Science (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Software Systems (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Databases & Information Systems (AREA)
  • Evolutionary Computation (AREA)
  • Artificial Intelligence (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Mathematical Physics (AREA)
  • Computing Systems (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Computational Linguistics (AREA)
  • Bioethics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SG11202009696WA 2018-04-13 2019-04-15 Machine learning implementation for multi-analyte assay of biological samples SG11202009696WA (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201862657602P 2018-04-13 2018-04-13
US201862679641P 2018-06-01 2018-06-01
US201862679587P 2018-06-01 2018-06-01
US201862731557P 2018-09-14 2018-09-14
US201862742799P 2018-10-08 2018-10-08
US201862749955P 2018-10-24 2018-10-24
US201862767435P 2018-11-14 2018-11-14
US201862767369P 2018-11-14 2018-11-14
US201962804614P 2019-02-12 2019-02-12
US201962824709P 2019-03-27 2019-03-27
PCT/US2019/027565 WO2019200410A1 (en) 2018-04-13 2019-04-15 Machine learning implementation for multi-analyte assay of biological samples

Publications (1)

Publication Number Publication Date
SG11202009696WA true SG11202009696WA (en) 2020-10-29

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202009696WA SG11202009696WA (en) 2018-04-13 2019-04-15 Machine learning implementation for multi-analyte assay of biological samples

Country Status (8)

Country Link
US (3) US11681953B2 (de)
EP (1) EP3776381A4 (de)
JP (2) JP7455757B2 (de)
KR (1) KR20200143462A (de)
AU (1) AU2019253118B2 (de)
CA (1) CA3095056A1 (de)
SG (1) SG11202009696WA (de)
WO (1) WO2019200410A1 (de)

Families Citing this family (117)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019060716A1 (en) 2017-09-25 2019-03-28 Freenome Holdings, Inc. SAMPLE EXTRACTION METHODS AND SYSTEMS
US11461891B2 (en) * 2018-03-06 2022-10-04 Case Western Reserve University Phenotyping tumor infiltrating lymphocytes on hematoxylin and eosin (HandE) stained tissue images to predict recurrence in lung cancer
US11569981B1 (en) * 2018-08-28 2023-01-31 Amazon Technologies, Inc. Blockchain network based on machine learning-based proof of work
US11719618B2 (en) * 2018-08-28 2023-08-08 Essenlix Corporation Assay accuracy improvement
AU2019356497A1 (en) * 2018-10-08 2021-03-18 Freenome Holdings, Inc. Transcription factor profiling
US11308325B2 (en) * 2018-10-16 2022-04-19 Duke University Systems and methods for predicting real-time behavioral risks using everyday images
JP7568276B2 (ja) 2018-12-28 2024-10-16 国立大学法人大阪大学 個体の形質情報を予測するためのシステムまたは方法
WO2020150258A1 (en) * 2019-01-15 2020-07-23 Luminist, Inc. Methods and systems for detecting liver disease
CN114341619A (zh) * 2019-04-05 2022-04-12 Essenlix 公司 测定准确度以及可靠性提高
AU2020313915A1 (en) * 2019-07-12 2022-02-24 Tempus Ai, Inc. Adaptive order fulfillment and tracking methods and systems
US20210062272A1 (en) * 2019-08-13 2021-03-04 10X Genomics, Inc. Systems and methods for using the spatial distribution of haplotypes to determine a biological condition
US11829871B2 (en) * 2019-08-20 2023-11-28 Lg Electronics Inc. Validating performance of a neural network trained using labeled training data
US20220351864A1 (en) * 2019-09-30 2022-11-03 Hoffmann-La Roche Inc. Means and methods for assessing huntington's disease (hd)
CN117036248A (zh) * 2019-10-01 2023-11-10 10X基因组学有限公司 用于识别组织样品中的形态学模式的系统和方法
US11367189B2 (en) * 2019-10-18 2022-06-21 Carnegie Mellon University Method for object detection using hierarchical deep learning
CN111833965B (zh) * 2019-11-08 2024-06-04 中国科学院北京基因组研究所(国家生物信息中心) 一种尿沉渣基因组dna的分类方法、装置和用途
US11593590B2 (en) 2019-11-25 2023-02-28 Essenlix Corporation Efficient training and accuracy improvement of imaging based assay
WO2021111410A1 (en) * 2019-12-05 2021-06-10 Multiplai Health Ltd. Analysis of selectively normalized spatial representations of data
WO2021110987A1 (en) * 2019-12-06 2021-06-10 Life & Soft Methods and apparatuses for diagnosing cancer from cell-free nucleic acids
US20230135171A1 (en) * 2019-12-24 2023-05-04 Lexent Bio, Inc. Methods and systems for molecular disease assessment via analysis of circulating tumor dna
CN111048207B (zh) * 2019-12-27 2023-06-16 四川九八村信息科技有限公司 一种供血浆者评价方法及系统
CN113052199A (zh) * 2019-12-28 2021-06-29 中移(成都)信息通信科技有限公司 病情检测模型的训练方法、装置、设备及计算机存储介质
US20230055370A1 (en) 2020-01-09 2023-02-23 Healios Gmbh Methods for staging of diseases
EP3854887A1 (de) * 2020-01-23 2021-07-28 Institut Jean Paoli & Irène Calmettes In vitro verfahren zur identifizierung effizienter therapeutischer molekule zur behandlung des pankreatischen duktalen adenokarzinoms
AU2021213150A1 (en) 2020-01-30 2022-08-04 Prognomiq Inc Lung biomarkers and methods of use thereof
CN111351942B (zh) * 2020-02-25 2024-03-26 北京尚医康华健康管理有限公司 肺癌肿瘤标志物筛选系统及肺癌风险分析系统
EP4115427A1 (de) * 2020-03-04 2023-01-11 Grail, LLC Systeme und verfahren zur bestimmung des krebszustands mit autoencodern
WO2021188354A1 (en) * 2020-03-14 2021-09-23 DataRobot, Inc. Automated and adaptive design and training of neural networks
CN111584064A (zh) * 2020-03-27 2020-08-25 湖州市中心医院 一种结、直肠癌转移预测系统及其使用方法
JP2023524627A (ja) * 2020-03-31 2023-06-13 フリーノム ホールディングス,インク. 核酸のメチル化分析による結腸直腸癌を検出するための方法およびシステム
WO2021202620A1 (en) * 2020-03-31 2021-10-07 The Board Of Trustees Of The Leland Stanford Junior University Metabolomics approach combined with machine learning to recognize a medical condition
US12080426B2 (en) * 2020-04-06 2024-09-03 University Of Florida Research Foundation, Incorporated Functional deep neural network for high-dimensional data analysis
GB202006144D0 (en) * 2020-04-27 2020-06-10 Univ Oxford Innovation Ltd Method of diagnosing a biological entity, and diagnostic device
CA3181389A1 (en) * 2020-04-29 2021-11-04 Freenome Holdings, Inc. Rna markers and methods for identifying colon cell proliferative disorders
CA3177168A1 (en) * 2020-04-30 2021-11-04 Dermot P. Mcgovern Methods and systems for assessing fibrotic disease with deep learning
IL297949A (en) * 2020-05-04 2023-01-01 Carmel Haifa Univ Economic Corporation Ltd Predicting the biological role of tissue receptors
CN111583998B (zh) * 2020-05-06 2023-05-02 西安交通大学 一种考虑拷贝数变异因素的基因组结构变异分型方法
US11574140B2 (en) * 2020-05-08 2023-02-07 PAIGE.AI, Inc. Systems and methods to process electronic images to determine salient information in digital pathology
WO2021252514A1 (en) * 2020-06-09 2021-12-16 Zymergen Inc. Metabolite fingerprinting
CA3177118A1 (en) * 2020-06-16 2021-12-23 Ruth E. MAUNTZ Methods for analysis of cell-free rna
US20230274834A1 (en) * 2020-07-22 2023-08-31 Spora Health, Inc. Model-based evaluation of assessment questions, assessment answers, and patient data to detect conditions
US20220028547A1 (en) * 2020-07-22 2022-01-27 Iterative Scopes, Inc. Systems and methods for analysis of medical images for scoring of inflammatory bowel disease
US20220042106A1 (en) * 2020-08-06 2022-02-10 Agendia NV Systems and methods of using cell-free nucleic acids to tailor cancer treatment
CN112002380B (zh) * 2020-08-14 2023-05-05 四川大学 基于机器学习的高生成热含能材料的自适应设计方法
US11909482B2 (en) * 2020-08-18 2024-02-20 Qualcomm Incorporated Federated learning for client-specific neural network parameter generation for wireless communication
EP4200874A4 (de) * 2020-08-19 2024-09-11 Tempus Ai Inc Systeme und verfahren zur homogenisierung von ungleichen datensätzen
US11769048B2 (en) * 2020-09-15 2023-09-26 Microsoft Technology Licensing, Llc Recommending edges via importance aware machine learned model
CN116210011A (zh) * 2020-09-23 2023-06-02 富士胶片株式会社 特征量选择方法、特征量选择程序、及特征量选择装置、多类分类方法、多类分类程序、及多类分类装置、以及特征量集
KR20230079198A (ko) * 2020-10-05 2023-06-05 프리놈 홀딩스, 인크. 결장 세포 증식성 장애의 조기 검출을 위한 마커
CN112233722B (zh) * 2020-10-19 2024-01-30 北京诺禾致源科技股份有限公司 品种鉴定的方法、其预测模型的构建方法和装置
US20230417694A1 (en) * 2020-11-16 2023-12-28 Nathan Swami Automated classification of biological subpopulations using impedance parameters
CN112466389B (zh) * 2020-12-04 2024-05-17 深圳市新合生物医疗科技有限公司 一种基于机器学习算法获取肿瘤标记物的方法和系统
AU2021401813A1 (en) * 2020-12-17 2023-07-06 Dana-Farber Cancer Institute, Inc. Methods of cancer detection using extraembryonically methylated cpg islands
IL303811A (en) * 2020-12-21 2023-08-01 Univ Johns Hopkins Detection of lung cancer through cell dissection without DNA
JP2024505333A (ja) * 2020-12-21 2024-02-06 フリーノム ホールディングス,インク. 結腸細胞増殖障害の早期検出のためのマーカー
US20240085304A1 (en) * 2021-01-15 2024-03-14 Essenlix Corporation Imaging Based Assay Accuracy Improvement Through Guided Training
CN112837743B (zh) * 2021-02-04 2024-03-26 东北大学 一种基于机器学习的药物重定位方法
WO2022203093A1 (ko) * 2021-03-22 2022-09-29 이원다이애그노믹스(주) 암 발생여부를 진단 또는 예측하는 방법
WO2022212583A1 (en) * 2021-03-31 2022-10-06 PrognomIQ, Inc. Multi-omic assessment
JP2024516522A (ja) * 2021-03-31 2024-04-16 プログノミック インコーポレイテッド マルチオミクス評価
US20220328155A1 (en) * 2021-04-09 2022-10-13 Endocanna Health, Inc. Machine-Learning Based Efficacy Predictions Based On Genetic And Biometric Information
CN113130004B (zh) * 2021-04-27 2024-05-14 上海海事大学 一种识别阿尔茨海默症相关生物标志物的相关性分析方法
WO2022240875A1 (en) * 2021-05-13 2022-11-17 Scipher Medicine Corporation Assessing responsiveness to therapy
EP4341701A1 (de) * 2021-05-20 2024-03-27 Clara Foods Co. Systeme und verfahren zur algorithmischen schätzung von proteinkonzentrationen
CN113355421B (zh) * 2021-07-03 2023-02-28 南京世和基因生物技术股份有限公司 肺癌早筛标志物、模型构建方法、检测装置以及计算机可读取介质
US20230039614A1 (en) * 2021-08-06 2023-02-09 Grail, Llc Microsimulation of multi-cancer early detection effects using parallel processing and integration of future intercepted incidences over time
CN113718031B (zh) * 2021-08-17 2022-05-20 浙江大学医学院附属妇产科医院 一种卵巢癌早期诊断组合物的建立
WO2023023282A1 (en) * 2021-08-19 2023-02-23 Rheos Medicines, Inc. Transcriptional subsetting of patient cohorts based on metabolic pathway activity
JP2024534992A (ja) 2021-09-13 2024-09-26 プログノミック インコーポレイテッド 生体分子の増強された検出および定量
CN113823356B (zh) * 2021-09-27 2024-05-28 电子科技大学长三角研究院(衢州) 一种甲基化位点识别方法及装置
EP4409436A1 (de) * 2021-09-30 2024-08-07 Algorithmic Biologics Private Limited System zum nachweis und zur quantifizierung mehrerer moleküle in mehreren biologischen proben
JPWO2023074829A1 (de) * 2021-10-29 2023-05-04
US12100484B2 (en) 2021-11-01 2024-09-24 Matterworks Inc Methods and compositions for analyte quantification
US20230137741A1 (en) 2021-11-01 2023-05-04 Matterworks Inc Methods and compositions for analyte quantification
EP4427227A1 (de) * 2021-11-01 2024-09-11 Personalis, Inc. Bestimmung von fragmentomischen signaturen auf basis von latenten variablen von nukleinsäuremolekülen
EP4184514A1 (de) * 2021-11-23 2023-05-24 Eone Reference Laboratory Vorrichtung und verfahren zur krebsdiagnose unter verwendung von flüssigkeitsbiopsiedaten
CN113872024A (zh) * 2021-12-01 2021-12-31 中国工程物理研究院电子工程研究所 面向光纤激光系统多源物理监测量的智能故障诊断方法
EP4445389A1 (de) * 2021-12-08 2024-10-16 Artera Inc. Verfahren und systeme zur digitalen pathologiebeurteilung von krebs durch tiefenlernen
WO2023154967A2 (en) * 2022-02-14 2023-08-17 Venn Biosciences Corporation Diagnosis of colorectal cancer using targeted quantification of site-specific protein glycosylation
CN114694748B (zh) * 2022-02-22 2022-10-28 中国人民解放军军事科学院军事医学研究院 一种基于预后信息与强化学习的蛋白质组学分子分型方法
WO2023164672A2 (en) * 2022-02-24 2023-08-31 Venn Biosciences Corporation Sample preparation for glycoproteomic analysis that includes diagnosis of disease
KR102491322B1 (ko) * 2022-03-29 2023-01-27 주식회사 아이엠비디엑스 암 진단을 위한 다중 분석 예측 모델의 제조 방법
WO2023190136A1 (ja) * 2022-03-30 2023-10-05 富士フイルム株式会社 学習システム、決定システム、及び予測システム、並びに学習方法、決定方法、及び予測方法
WO2023212509A1 (en) * 2022-04-25 2023-11-02 Whitehead Institute For Biomedical Research Methods And Systems For Quantifying Partitioning Of Agents In Vivo Based on Partitioning Of Agents In Vitro
WO2023212116A1 (en) * 2022-04-26 2023-11-02 Ge Healthcare Limited Model generation apparatus for therapeutic prediction and associated methods and models
WO2023212332A1 (en) * 2022-04-29 2023-11-02 Icahn School Of Medicine At Mount Sinai Biomarker set identification for lyme disease
WO2023220192A1 (en) * 2022-05-11 2023-11-16 Foundation Medicine, Inc. Methods and systems for predicting an origin of an alteration in a sample using a statistical model
WO2023225004A1 (en) * 2022-05-16 2023-11-23 Bioscreening & Diagnostics Llc Prediction of alzheimer's disease
WO2023235878A2 (en) * 2022-06-03 2023-12-07 Freenome Holdings, Inc. Markers for the early detection of colon cell proliferative disorders
WO2023239714A1 (en) * 2022-06-07 2023-12-14 Pangea Biomed Ltd Predicting patient response to cancer therapy via histopathology images
KR20230168942A (ko) 2022-06-07 2023-12-15 주식회사 베르티스 단백질 정량을 위한 질량분석 피크의 자동 선별 방법
CN114724550B (zh) * 2022-06-10 2022-09-06 慕思健康睡眠股份有限公司 一种基于睡眠的音频识别方法、装置、床垫及存储介质
CN114973245B (zh) * 2022-06-20 2024-03-15 重庆医科大学 基于机器学习的细胞外囊泡分类方法、装置、设备及介质
WO2024006142A1 (en) * 2022-07-01 2024-01-04 Bioaffinity Technologies, Inc. Detection of early-stage lung cancer in sputum using automated flow cytometry and machine learning
WO2024010875A1 (en) * 2022-07-06 2024-01-11 The Regents Of The University Of California Repeat-aware profiling of cell-free rna
WO2024026413A2 (en) * 2022-07-27 2024-02-01 Durin Technologies, Inc. Early detection and monitoring of neurodegenerative diseases using a multi-disease diagnostic platform
CN115240854B (zh) * 2022-07-29 2023-10-03 中国医学科学院北京协和医院 一种胰腺炎预后数据的处理方法及其系统
CN115032376B (zh) * 2022-08-11 2022-10-21 乐比(广州)健康产业有限公司 一种驱蚊止痒组合物成分检测方法
CN115497630B (zh) * 2022-08-24 2023-11-03 中国医学科学院北京协和医院 一种急性重症溃疡性结肠炎数据的处理方法及其系统
CN115762796A (zh) * 2022-09-27 2023-03-07 京东方科技集团股份有限公司 目标模型的获取方法、预后评估值确定方法、装置、设备及介质
US20240117435A1 (en) * 2022-10-05 2024-04-11 Grail, Llc Systems and methods for performing methylation-based risk stratification for myelodysplastic syndromes
JP2024064128A (ja) * 2022-10-27 2024-05-14 チューニングフォーク・バイオ・インク 抗原探索方法及び抗原探索システム
CN115527612B (zh) * 2022-10-28 2023-11-14 四川天瓴创新科技集团有限公司 基于数值特征表达的基因组二四代融合组装方法及系统
WO2024097224A1 (en) * 2022-10-31 2024-05-10 William Marsh Rice University Analysis of mixture using combination of spectroscopy and machine learning
WO2024098073A1 (en) * 2022-11-06 2024-05-10 The Johns Hopkins University Detecting liver cancer using cell-free dna fragmentation
US20240161867A1 (en) * 2022-11-16 2024-05-16 Grail, Llc Optimization of model-based featurization and classification
WO2024117233A1 (ja) * 2022-12-02 2024-06-06 国立大学法人東京大学 一粒子生物分析のための方法及び装置
CN116230082B (zh) * 2022-12-06 2024-05-14 序科码医学检验实验室(广州)有限公司 基于样品基因型的数据拆分的无标记多样品混合单细胞测序方法
KR20240105981A (ko) * 2022-12-29 2024-07-08 씨제이올리브네트웍스 주식회사 인공지능에 기반한 미생물의 종을 예측하는 방법 및 장치
WO2024168114A1 (en) * 2023-02-08 2024-08-15 Battelle Memorial Institute Technologies for individualized metagenomic profiling
US20240273718A1 (en) * 2023-02-15 2024-08-15 Insitro, Inc. Machine-learning-enabled predictive biomarker discovery and patient stratification using standard-of-care data
WO2024187092A1 (en) * 2023-03-08 2024-09-12 The Trustees Of Dartmouth College Hierarchical artificial intelligence tumor classifier for tracing tissue of origin and tumor type
CN116622822A (zh) * 2023-03-17 2023-08-22 四川大学 一种多重混样直接rna纳米孔测序方法
CN116561627B (zh) * 2023-05-11 2024-04-16 中南大学 用于确定胚胎移植类型的方法、装置、处理器及存储介质
CN117890320B (zh) * 2024-01-22 2024-08-23 冠县新瑞实业有限公司 基于数据融合的面粉蛋白质含量在线监测的方法
CN117935914B (zh) * 2024-03-22 2024-06-14 北京求臻医学检验实验室有限公司 一种意义未明的克隆性造血识别及其应用方法
CN118366547B (zh) * 2024-06-19 2024-08-23 南京世和基因生物技术股份有限公司 基因标志物在多癌种早筛中的应用、早筛模型构建方法以及检测装置

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006044017A2 (en) * 2004-08-13 2006-04-27 Jaguar Bioscience Inc. Systems and methods for identifying diagnostic indicators
JP2008527351A (ja) 2005-01-06 2008-07-24 イースタン バージニア メディカル スクール 前立腺癌のバイオマーカーとしてのアポリポタンパク質a−iiアイソフォーム
CN101268367A (zh) * 2005-06-24 2008-09-17 赛弗吉生物系统公司 卵巢癌的生物标记
EP1975252A1 (de) 2007-03-29 2008-10-01 INSERM (Institut National de la Santé et de la Recherche Medicale) Verfahren zur Vorhersage oder Diagnose einer Schilddrüsenkrankheit
ES2781754T3 (es) 2008-11-07 2020-09-07 Adaptive Biotechnologies Corp Métodos para supervisar las condiciones por análisis de secuencia
US9495515B1 (en) * 2009-12-09 2016-11-15 Veracyte, Inc. Algorithms for disease diagnostics
US10295540B1 (en) * 2009-02-13 2019-05-21 Cancer Genetics, Inc. Systems and methods for phenotypic classification using biological samples of different sample types
US10446272B2 (en) * 2009-12-09 2019-10-15 Veracyte, Inc. Methods and compositions for classification of samples
CN103874770A (zh) 2011-08-08 2014-06-18 卡里斯生命科学卢森堡控股有限责任公司 生物标志物组合物和方法
EP2613278A2 (de) 2011-12-05 2013-07-10 Koninklijke Philips Electronics N.V. Retroaktive Gewinnung von klinisch relevanten Informationen aus Patientensequenzierungsdaten zur Unterstützung bei klinischen Entscheidungen
WO2014012176A1 (en) * 2012-07-20 2014-01-23 Diagnocure Inc. Methods, kits and compositions for providing a clinical assessment of prostate cancer
CA2893158A1 (en) * 2012-11-30 2014-06-05 Applied Proteomics, Inc. Method for evaluation of presence of or risk of colon tumors
US20140274767A1 (en) * 2013-01-23 2014-09-18 The Johns Hopkins University Dna methylation markers for metastatic prostate cancer
US20150324527A1 (en) * 2013-03-15 2015-11-12 Northrop Grumman Systems Corporation Learning health systems and methods
SG11201506723XA (en) * 2013-03-15 2015-09-29 Veracyte Inc Methods and compositions for classification of samples
US9710606B2 (en) * 2014-10-21 2017-07-18 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues
US10388407B2 (en) * 2014-10-21 2019-08-20 uBiome, Inc. Method and system for characterizing a headache-related condition
WO2016094330A2 (en) 2014-12-08 2016-06-16 20/20 Genesystems, Inc Methods and machine learning systems for predicting the liklihood or risk of having cancer
CN107208149B (zh) 2015-01-30 2021-09-21 深圳华大生命科学研究院 结直肠癌相关疾病的生物标志物
AU2016222788B2 (en) * 2015-02-24 2022-03-31 Adaptive Biotechnologies Corp. Methods for diagnosing infectious disease and determining HLA status using immune repertoire sequencing
WO2017065959A2 (en) * 2015-09-25 2017-04-20 Veracyte, Inc. Methods and compositions that utilize transcriptome sequencing data in machine learning-based classification
CN108369659B (zh) * 2015-09-30 2020-11-06 扎斯特有限公司 用于识别具有目标性质的实体的系统和方法
CN108474040B (zh) 2015-10-09 2023-05-16 夸登特健康公司 使用无细胞dna的基于群体的治疗推荐
JP6903672B2 (ja) 2016-03-08 2021-07-14 マグアレイ,インコーポレイテッド 肺癌の診断および治療のための蛋白質と自己抗体バイオマーカー
US11499196B2 (en) * 2016-06-07 2022-11-15 The Regents Of The University Of California Cell-free DNA methylation patterns for disease and condition analysis
WO2018009723A1 (en) 2016-07-06 2018-01-11 Guardant Health, Inc. Methods for fragmentome profiling of cell-free nucleic acids
JP2019521706A (ja) 2016-07-13 2019-08-08 ユーバイオーム, インコーポレイテッド 微生物ゲノム薬理学のための方法およびシステム
US20190391151A1 (en) * 2017-03-07 2019-12-26 Elypta Ab Cancer biomarkers
US10318350B2 (en) * 2017-03-20 2019-06-11 International Business Machines Corporation Self-adjusting environmentally aware resource provisioning
US10650911B2 (en) * 2017-06-13 2020-05-12 Bostongene Corporation Systems and methods for generating, visualizing and classifying molecular functional profiles
CA3072195A1 (en) * 2017-08-07 2019-04-04 The Johns Hopkins University Methods and materials for assessing and treating cancer
CA3095030A1 (en) * 2018-03-30 2019-10-03 Juno Diagnostics, Inc. Deep learning-based methods, devices, and systems for prenatal testing
CA3094717A1 (en) * 2018-04-02 2019-10-10 Grail, Inc. Methylation markers and targeted methylation probe panels

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