SG11202009338SA - Modulators of g-protein coupled receptors - Google Patents
Modulators of g-protein coupled receptorsInfo
- Publication number
- SG11202009338SA SG11202009338SA SG11202009338SA SG11202009338SA SG11202009338SA SG 11202009338S A SG11202009338S A SG 11202009338SA SG 11202009338S A SG11202009338S A SG 11202009338SA SG 11202009338S A SG11202009338S A SG 11202009338SA SG 11202009338S A SG11202009338S A SG 11202009338SA
- Authority
- SG
- Singapore
- Prior art keywords
- modulators
- protein coupled
- coupled receptors
- receptors
- protein
- Prior art date
Links
- 102000003688 G-Protein-Coupled Receptors Human genes 0.000 title 1
- 108090000045 G-Protein-Coupled Receptors Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/545—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862647604P | 2018-03-23 | 2018-03-23 | |
| PCT/US2019/023726 WO2019183577A1 (fr) | 2018-03-23 | 2019-03-22 | Modulateurs de récepteurs couplés à la protéine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202009338SA true SG11202009338SA (en) | 2020-10-29 |
Family
ID=67986596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202009338SA SG11202009338SA (en) | 2018-03-23 | 2019-03-22 | Modulators of g-protein coupled receptors |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11535660B1 (fr) |
| EP (1) | EP3768294A4 (fr) |
| JP (1) | JP7526716B2 (fr) |
| KR (1) | KR20210008834A (fr) |
| CN (1) | CN112236161A (fr) |
| AR (1) | AR115016A1 (fr) |
| AU (1) | AU2019237507A1 (fr) |
| BR (1) | BR112020019148A2 (fr) |
| CA (1) | CA3094820A1 (fr) |
| EA (1) | EA202092269A1 (fr) |
| IL (2) | IL311177A (fr) |
| MX (1) | MX2020009950A (fr) |
| PH (1) | PH12020551539A1 (fr) |
| SG (1) | SG11202009338SA (fr) |
| TW (1) | TWI840348B (fr) |
| WO (1) | WO2019183577A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CR20230530A (es) * | 2021-05-13 | 2024-02-19 | Carmot Therapeutics Inc | Moduladores de los receptores acoplados a proteínas g. |
| WO2024033374A1 (fr) | 2022-08-11 | 2024-02-15 | Syngenta Crop Protection Ag | Nouveaux composés arylcarboxamide ou arylthioamide |
| WO2024089216A1 (fr) | 2022-10-27 | 2024-05-02 | Syngenta Crop Protection Ag | Nouveaux composés hétéroaryl-carboxamides contenant du soufre |
| WO2024096361A1 (fr) * | 2022-11-04 | 2024-05-10 | 주식회사 엘지화학 | Support d'enregistrement d'hologramme et élément optique le comprenant |
| KR20240064272A (ko) * | 2022-11-04 | 2024-05-13 | 주식회사 엘지화학 | 불소계 화합물, 광중합성 조성물, 홀로그램 기록 매체, 이의 제조 방법 및 이를 포함하는 광학 소자 |
| WO2024126650A1 (fr) | 2022-12-15 | 2024-06-20 | Syngenta Crop Protection Ag | Nouveaux composés bicycliques-carboxamide utiles en tant que pesticides |
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| CN1072649C (zh) | 1995-09-13 | 2001-10-10 | 武田药品工业株式会社 | 苯并氧杂吖庚因化合物,其生产方法和用途 |
| US6432947B1 (en) | 1997-02-19 | 2002-08-13 | Berlex Laboratories, Inc. | N-heterocyclic derivatives as NOS inhibitors |
| WO1999043707A1 (fr) | 1998-02-27 | 1999-09-02 | Novo Nordisk A/S | Derives de glp-1 modifies a l'extremite n-terminale |
| CZ295768B6 (cs) * | 1998-12-07 | 2005-10-12 | Societe De Conseils De Recherches Et D'application | Analogy GLP-1, mající beta-alanin na pozici 35, jejich použití a farmaceutické prostředky je obsahující |
| WO2001062765A2 (fr) | 1999-02-26 | 2001-08-30 | Arena Pharmaceuticals, Inc. | Modulateurs a petites molecules du recepteur six couple a la proteine g |
| CA2383794A1 (fr) | 1999-09-07 | 2001-03-15 | Conjuchem Inc. | Methodes et compositions destinees a la production d'agents anticancereux a activite prolongee |
| CA2416384A1 (fr) | 2000-07-17 | 2003-01-16 | Takeda Chemical Industries, Ltd. | Derives de sulfonate, leur production et utilisation |
| EP1556032A1 (fr) | 2002-11-01 | 2005-07-27 | Takeda Pharmaceutical Company Limited | Agent pour la prevention ou le traitement de neuropathie |
| WO2004041266A1 (fr) | 2002-11-08 | 2004-05-21 | Takeda Pharmaceutical Company Limited | Agent de controle de la fonction recepteur |
| EP1564213A4 (fr) | 2002-11-22 | 2009-05-27 | Takeda Pharmaceutical | Derives d'imidazole, leur procede de production et d'utilisation |
| US20050059605A1 (en) * | 2003-01-31 | 2005-03-17 | Krishna Peri | Chemically modified metabolites of regulatory peptides and methods of producing and using same |
| US7820837B2 (en) | 2003-05-30 | 2010-10-26 | Takeda Pharmaceutical Company Limited | Condensed ring compound |
| BRPI0414539B8 (pt) | 2003-09-19 | 2021-05-25 | Novo Nordisk As | composto, composição farmacêutica, e, uso de um composto |
| WO2005030740A1 (fr) | 2003-09-30 | 2005-04-07 | Takeda Pharmaceutical Company Limited | Derive thiazoline et utilisation |
| US7820673B2 (en) | 2003-12-17 | 2010-10-26 | Takeda Pharmaceutical Company Limited | Urea derivative, process for producing the same, and use |
| RU2006126978A (ru) | 2003-12-25 | 2008-01-27 | Такеда Фармасьютикал Компани Лимитед (Jp) | Производные 3-(4-бензилоксифенил)пропановой кислоты |
| EP1698624B1 (fr) | 2003-12-26 | 2012-06-27 | Takeda Pharmaceutical Company Limited | Derives d'acide phenylpropanoique |
| CA2560111A1 (fr) | 2004-03-15 | 2005-09-22 | Takeda Pharmaceutical Company Limited | Derive de l'acide aminophenylpropanoique |
| US7517910B2 (en) | 2004-03-30 | 2009-04-14 | Takeda Pharmaceutical Company Limited | Alkoxyphenylpropanoic acid derivatives |
| TWI396686B (zh) | 2004-05-21 | 2013-05-21 | Takeda Pharmaceutical | 環狀醯胺衍生物、以及其製品和用法 |
| US20060275288A1 (en) | 2005-01-20 | 2006-12-07 | Grihalde Nelson D | GLP-1 receptor agonist and allosteric modulator monoclonal antibodies and uses thereof |
| WO2006112549A1 (fr) | 2005-04-20 | 2006-10-26 | Takeda Pharmaceutical Company Limited | Compose heterocyclique fusionne |
| CA2607566A1 (fr) | 2005-05-06 | 2006-11-16 | Bayer Pharmaceuticals Corporation | Agonistes vis-a-vis du recepteur peptidique de type glucagon 1 (glp-1) et procedes pharmacologiques d'utilisation |
| EP1916234B1 (fr) | 2005-07-29 | 2014-11-12 | Takeda Pharmaceutical Company Limited | Composé d'acide cyclopropanecarboxylique |
| US20090054435A1 (en) | 2005-07-29 | 2009-02-26 | Hiroshi Imoto | Phenoxyalkanoic Acid Compound |
| MX2008001386A (es) | 2005-08-10 | 2008-04-07 | Takeda Pharmaceutical | Agente terapeutico para diabetes. |
| JP2007063225A (ja) | 2005-09-01 | 2007-03-15 | Takeda Chem Ind Ltd | イミダゾピリジン化合物 |
| CN101420941A (zh) * | 2006-04-11 | 2009-04-29 | 艾尼纳制药公司 | Gpr119受体激动剂用于增加骨质量和用于治疗骨质疏松症的用途,和其相关组合疗法 |
| PT2248812E (pt) | 2006-06-27 | 2014-03-12 | Takeda Pharmaceutical | Compostos cíclicos fundidos como moduladores do receptor gpr40 |
| JP5399244B2 (ja) * | 2006-08-17 | 2014-01-29 | アミリン・ファーマシューティカルズ，リミテッド・ライアビリティ・カンパニー | 選択可能な特性を持つｄｐｐ−ｉｖ耐性ｇｉｐハイブリッドポリペプチド |
| US8492405B2 (en) | 2006-10-18 | 2013-07-23 | Takeda Pharmaceutical Company Limited | Glucokinase-activating fused heterocyclic compounds and methods of treating diabetes and obesity |
| MX2009003972A (es) | 2006-10-19 | 2009-04-27 | Takeda Pharmaceutical | Compuesto de indol. |
| EP2128138A1 (fr) | 2007-01-29 | 2009-12-02 | Takeda Pharmaceutical Company Limited | Composé de pyrazole |
| BRPI0807014A2 (pt) | 2007-02-09 | 2014-04-22 | Takeda Pharmaceutical | Composto, pró-droga, agente farmacêutico, métodos para melhorar a resistência a insulina em um mamífero, método para a profilaxia ou o tratamento de diabetes em um mamífero, e, uso de um composto. |
| EP2149550A4 (fr) | 2007-04-27 | 2010-08-11 | Takeda Pharmaceutical | Composé hétérocyclique à cinq chaînons à teneur en azote |
| US20110301155A1 (en) | 2007-06-19 | 2011-12-08 | Tsuneo Yasuma | Indazole compounds for activating glucokinase |
| CN102105159B (zh) | 2008-06-17 | 2015-07-08 | 印第安纳大学研究及科技有限公司 | 基于gip的混合激动剂用于治疗代谢紊乱和肥胖症 |
| TW201006821A (en) * | 2008-07-16 | 2010-02-16 | Bristol Myers Squibb Co | Pyridone and pyridazone analogues as GPR119 modulators |
| US20120148586A1 (en) | 2009-08-27 | 2012-06-14 | Joyce Ching Tsu Chou | Glucagon-like protein-1 receptor (glp-1r) agonists for treating autoimmune disorders |
| US8426414B2 (en) | 2009-10-09 | 2013-04-23 | Bristol-Myers Squibb Company | Modulators of G protein-coupled receptor 88 |
| MX2012008603A (es) * | 2010-01-27 | 2013-01-25 | Univ Indiana Res & Tech Corp | Conjugados de antagonista de glucagon-agonista de gip y composiciones para el tratamiento de desordenes metabolicos y obesidad. |
| US20120021979A1 (en) | 2010-06-24 | 2012-01-26 | Vanderbilt University | GLP-1 receptor modulation of addiction, neuropsychiatric disorders and erectile dysfunction |
| US20150087586A1 (en) | 2012-03-29 | 2015-03-26 | Cebix, Inc. | Pegylated c-peptide |
| WO2014074218A1 (fr) * | 2012-11-12 | 2014-05-15 | Redwood Bioscience, Inc. | Composés et procédés pour produire un conjugué |
| US9764037B2 (en) | 2012-12-06 | 2017-09-19 | Victoria Link Limited | Conjugate compounds |
| US9766239B2 (en) | 2013-03-13 | 2017-09-19 | Arizona Board Of Regents On Behalf Of Arizona State University | Synbodies for detection of human norovirus |
| AU2014300503B2 (en) | 2013-06-28 | 2018-11-22 | Auckland Uniservices Limited | Amino acid and peptide conjugates and conjugation process |
| WO2015031268A1 (fr) | 2013-08-26 | 2015-03-05 | Arizona Board Of Regents On Behalf Of Arizona State University | Corps de synthèse à affinité élevée pour la grippe |
| EP3218414A1 (fr) * | 2014-11-14 | 2017-09-20 | Angiochem Inc. | Conjugués comprenant une partie anticorps, un polypeptide capable de traverser la barrière hémato-encéphalique, et une cytokine |
| WO2016131893A1 (fr) | 2015-02-18 | 2016-08-25 | Medimmune Limited | Polypeptides de fusion de l'incrétine |
| CN105219802A (zh) * | 2015-10-10 | 2016-01-06 | 广西大学 | 胰岛组织特异性表达GIPRdn慢病毒载体及其应用 |
| GB2551945B (en) * | 2015-12-18 | 2021-09-08 | Heptares Therapeutics Ltd | Novel GLP-1 receptor agonist peptides |
-
2019
- 2019-03-22 IL IL311177A patent/IL311177A/en unknown
- 2019-03-22 AU AU2019237507A patent/AU2019237507A1/en active Pending
- 2019-03-22 SG SG11202009338SA patent/SG11202009338SA/en unknown
- 2019-03-22 MX MX2020009950A patent/MX2020009950A/es unknown
- 2019-03-22 BR BR112020019148-5A patent/BR112020019148A2/pt unknown
- 2019-03-22 IL IL277495A patent/IL277495B2/en unknown
- 2019-03-22 CA CA3094820A patent/CA3094820A1/fr active Pending
- 2019-03-22 CN CN201980032743.8A patent/CN112236161A/zh active Pending
- 2019-03-22 JP JP2021500508A patent/JP7526716B2/ja active Active
- 2019-03-22 KR KR1020207030531A patent/KR20210008834A/ko not_active Application Discontinuation
- 2019-03-22 US US17/040,653 patent/US11535660B1/en active Active
- 2019-03-22 EP EP19772275.4A patent/EP3768294A4/fr active Pending
- 2019-03-22 EA EA202092269A patent/EA202092269A1/ru unknown
- 2019-03-22 WO PCT/US2019/023726 patent/WO2019183577A1/fr active Application Filing
- 2019-03-25 TW TW108110353A patent/TWI840348B/zh active
- 2019-03-25 AR ARP190100749A patent/AR115016A1/es unknown
-
2020
- 2020-09-23 PH PH12020551539A patent/PH12020551539A1/en unknown
-
2022
- 2022-12-22 US US18/087,063 patent/US20230357347A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN112236161A (zh) | 2021-01-15 |
| MX2020009950A (es) | 2021-04-28 |
| CA3094820A1 (fr) | 2019-09-26 |
| BR112020019148A2 (pt) | 2021-01-26 |
| JP2021531259A (ja) | 2021-11-18 |
| EP3768294A4 (fr) | 2022-05-04 |
| IL277495B2 (en) | 2024-08-01 |
| IL277495A (en) | 2020-11-30 |
| AR115016A1 (es) | 2020-11-18 |
| IL277495B1 (en) | 2024-04-01 |
| US11535660B1 (en) | 2022-12-27 |
| EA202092269A1 (ru) | 2020-12-14 |
| KR20210008834A (ko) | 2021-01-25 |
| AU2019237507A1 (en) | 2020-10-08 |
| TW202012432A (zh) | 2020-04-01 |
| EP3768294A1 (fr) | 2021-01-27 |
| TWI840348B (zh) | 2024-05-01 |
| PH12020551539A1 (en) | 2021-06-07 |
| US20230357347A1 (en) | 2023-11-09 |
| IL311177A (en) | 2024-04-01 |
| WO2019183577A1 (fr) | 2019-09-26 |
| JP7526716B2 (ja) | 2024-08-01 |
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