SG11202004260YA - Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives - Google Patents

Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives

Info

Publication number
SG11202004260YA
SG11202004260YA SG11202004260YA SG11202004260YA SG11202004260YA SG 11202004260Y A SG11202004260Y A SG 11202004260YA SG 11202004260Y A SG11202004260Y A SG 11202004260YA SG 11202004260Y A SG11202004260Y A SG 11202004260YA SG 11202004260Y A SG11202004260Y A SG 11202004260YA
Authority
SG
Singapore
Prior art keywords
antihelmintic
quinoline
amino
preparing
carboxamide derivatives
Prior art date
Application number
SG11202004260YA
Other languages
English (en)
Inventor
Florian Erver
Frank Memmel
Thomas Himmler
Andreas Steib
Marc Nowakowski
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of SG11202004260YA publication Critical patent/SG11202004260YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J23/00Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
    • B01J23/38Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
    • B01J23/40Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals of the platinum group metals
    • B01J23/44Palladium
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Quinoline Compounds (AREA)
SG11202004260YA 2017-12-15 2018-12-14 Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives SG11202004260YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17207586 2017-12-15
PCT/EP2018/084964 WO2019115768A1 (en) 2017-12-15 2018-12-14 Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives

Publications (1)

Publication Number Publication Date
SG11202004260YA true SG11202004260YA (en) 2020-06-29

Family

ID=60673654

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202004260YA SG11202004260YA (en) 2017-12-15 2018-12-14 Process for preparing antihelmintic 4-amino-quinoline-3-carboxamide derivatives

Country Status (18)

Country Link
US (1) US11505544B2 (zh)
EP (1) EP3692037A1 (zh)
JP (1) JP2021506774A (zh)
KR (1) KR20200099548A (zh)
CN (1) CN111448192B (zh)
AU (1) AU2018382999B2 (zh)
BR (1) BR112020011901A2 (zh)
CA (1) CA3085675A1 (zh)
CL (1) CL2020001589A1 (zh)
CO (1) CO2020007222A2 (zh)
DO (1) DOP2020000118A (zh)
IL (1) IL275216A (zh)
MX (1) MX2020006185A (zh)
PH (1) PH12020550905A1 (zh)
SG (1) SG11202004260YA (zh)
TW (1) TWI809018B (zh)
UY (1) UY38009A (zh)
WO (1) WO2019115768A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202109786UA (en) 2019-03-19 2021-10-28 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic aza-benzothiophene and aza-benzofuran compounds
CN115667221A (zh) * 2020-04-09 2023-01-31 拜耳动物保健有限责任公司 作为驱虫化合物的取代的稠合嗪类
BR112022024156A2 (pt) 2020-05-29 2023-02-14 Boehringer Ingelheim Animal Health Usa Inc Compostos heterocílicos antelmínticos
EP4148052A1 (en) * 2021-09-09 2023-03-15 Bayer Animal Health GmbH New quinoline derivatives
TW202333665A (zh) 2021-11-01 2023-09-01 德商百靈佳殷格翰維美迪加股份有限公司 驅蟲吡咯幷嗒𠯤化合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2309882A1 (en) * 1997-12-22 1999-07-01 Pharmacia & Upjohn Company 4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents
JP4234344B2 (ja) 1999-12-28 2009-03-04 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホンアミド含有複素環化合物
KR100767000B1 (ko) 2000-02-03 2007-10-15 에자이 알앤드디 매니지먼트 가부시키가이샤 인테그린 발현 저해제
JP2008214323A (ja) 2007-03-08 2008-09-18 Kyowa Hakko Kogyo Co Ltd 皮膚疾患の治療及び/または予防剤
WO2013118071A1 (en) 2012-02-09 2013-08-15 Glenmark Pharmaceuticals S.A. BICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
AR098475A1 (es) * 2013-11-26 2016-06-01 Bayer Cropscience Ag Compuestos pesticidas y usos
EP3124482B1 (en) * 2014-03-24 2019-09-11 Guangdong Zhongsheng Pharmaceutical Co., Ltd Quinoline derivatives as smo inhibitors
RU2018126105A (ru) 2015-12-17 2020-01-17 Астекс Терапьютикс Лимитед Хинолин-3-карбоксамиды в качестве ингибиторов h-pgds
CN109890793B (zh) 2016-11-11 2022-11-18 拜耳动物保健有限责任公司 新的抗蠕虫药喹啉-3-甲酰胺衍生物

Also Published As

Publication number Publication date
MX2020006185A (es) 2020-09-03
IL275216A (en) 2020-07-30
TW201927773A (zh) 2019-07-16
AU2018382999A1 (en) 2020-05-28
US11505544B2 (en) 2022-11-22
TWI809018B (zh) 2023-07-21
CO2020007222A2 (es) 2020-11-20
EP3692037A1 (en) 2020-08-12
CN111448192A (zh) 2020-07-24
UY38009A (es) 2019-07-31
WO2019115768A1 (en) 2019-06-20
CA3085675A1 (en) 2019-06-20
AU2018382999B2 (en) 2023-11-23
KR20200099548A (ko) 2020-08-24
US20200308153A1 (en) 2020-10-01
DOP2020000118A (es) 2020-08-31
CL2020001589A1 (es) 2020-11-20
BR112020011901A2 (pt) 2020-11-24
PH12020550905A1 (en) 2021-05-17
RU2020123282A (ru) 2022-01-17
JP2021506774A (ja) 2021-02-22
CN111448192B (zh) 2024-04-12

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